Pathogens, Vol. 8, Pages 214: Rapid Discrimination of Methicillin-Resistant Staphylococcus aureus by MALDI-TOF MS Pathogens doi: 10.3390/pathogens8040214 Authors: Kim Kim Chung Chung Han Kim Methicillin-resistant Staphylococcus aureus (MRSA) is a serious pathogen in clinical settings and early detection is critical. Here, we investigated the MRSA discrimination potential of matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS)...
Fri Nov 01, 2019 02:00
Pathogens, Vol. 8, Pages 215: West Nile Virus Induced Cell Death in the Central Nervous System Pathogens doi: 10.3390/pathogens8040215 Authors: Peng Wang West Nile virus (WNV), a mosquito-borne, single-stranded flavivirus, has caused annual outbreaks of viral encephalitis in the United States since 1999. The virus induces acute infection with a clinical spectrum ranging from a mild flu-like febrile symptom to more severe neuroinvasive conditions, including meningitis, encephalitis,...
Fri Nov 01, 2019 02:00
Pharmaceutics, Vol. 11, Pages 573: Highly Water-Soluble Solid Dispersions of Honokiol: Preparation, Solubility, and Bioavailability Studies and Anti-Tumor Activity Evaluation Pharmaceutics doi: 10.3390/pharmaceutics11110573 Authors: Wang Wu Wang Wang Zhao Honokiol (HK), a well-tolerated natural product, has many multiple pharmacological activities. However, its poor water solubility and low bioavailability limit its clinical application and development. The aim of this...
Fri Nov 01, 2019 02:00
Pharmaceutics, Vol. 11, Pages 572: Nanomedicine Against Aβ Aggregation by β–Sheet Breaker Peptide Delivery: In Vitro Evidence Pharmaceutics doi: 10.3390/pharmaceutics11110572 Authors: Pederzoli Ruozi Duskey Hagmeyer Sauer Grabrucker Coelho Oddone Ottonelli Daini Zoli Vandelli Tosi Grabrucker The accumulation of amyloid β (Aβ) triggers a cascade of toxic events in Alzheimer’s disease (AD). The KLVFF peptide...
Fri Nov 01, 2019 02:00
Pharmaceutics, Vol. 11, Pages 570: Evaluation of Electrospun Poly(ε-Caprolactone)/Gelatin Nanofiber Mats Containing Clove Essential Oil for Antibacterial Wound Dressing Pharmaceutics doi: 10.3390/pharmaceutics11110570 Authors: Irem Unalan Stefan J. Endlein Benedikt Slavik Andrea Buettner Wolfgang H. Goldmann Rainer Detsch Aldo R. Boccaccini The objective of this study was to produce antibacterial poly(ε-caprolactone) (PCL)-gelatin (GEL) electrospun nanofiber...
Fri Nov 01, 2019 02:00
Pharmaceutics, Vol. 11, Pages 571: Silicon Nanotubes as Potential Therapeutic Platforms Pharmaceutics doi: 10.3390/pharmaceutics11110571 Authors: Nguyen T. Le Yuan Tian Roberto Gonzalez-Rodriguez Jeffery L. Coffer Silicon nanotubes (SiNTs) with unique well-defined structural morphologies have been successfully fabricated and recognized as a novel architecture in the nanoscale Si family. While the typical dendritic microstructure of mesoporous silicon prepared anodically has...
Fri Nov 01, 2019 02:00
Pharmaceutics, Vol. 11, Pages 569: High Potency of SN-38-Loaded Bovine Serum Albumin Nanoparticles Against Triple-Negative Breast Cancer Pharmaceutics doi: 10.3390/pharmaceutics11110569 Authors: Lin Chuang Cheng Lin Fang Triple-negative breast cancer (TNBC) is an aggressive type of breast cancer with a worse prognosis than other types. There are currently no specific approved treatments for TNBC. Albumin is a promising biomimetic material that may be fabricated into...
Fri Nov 01, 2019 02:00
Pharmacy, Vol. 7, Pages 145: BundlED Up: A Narrative Review of Antimicrobial Stewardship Initiatives and Bundles in the Emergency Department Pharmacy doi: 10.3390/pharmacy7040145 Authors: Maressa Santarossa Emily N. Kilber Eric Wenzler Fritzie S. Albarillo Ethan J. Sterk Antimicrobial stewardship (ASP) is becoming an increasingly high priority worldwide, yet the emergency department (ED) is an area where stewardship is often neglected. Implementing care bundles, guidelines,...
Fri Nov 01, 2019 02:00
Plants, Vol. 8, Pages 469: Fitness of Herbicide-Resistant Weeds: Current Knowledge and Implications for Management Plants doi: 10.3390/plants8110469 Authors: Vila-Aiub Herbicide resistance is the ultimate evidence of the extraordinary capacity of weeds to evolve under stressful conditions. Despite the extraordinary plant fitness advantage endowed by herbicide resistance mutations in agroecosystems under herbicide selection, resistance mutations are predicted to exhibit an adaptation...
Fri Nov 01, 2019 02:00
Psych, Vol. 1, Pages 491-503: Polypharmacy and Depressive Symptoms in U.S.-Born Mexican American Older Adults Psych doi: 10.3390/psych1010038 Authors: Shervin Assari Cheryl Wisseh Mohammed Saqib Hamid Helmi Mohsen Bazargan Background: Although some studies have suggested a link between polypharmacy and poor mental health, less is known about the association between polypharmacy and depressive symptomology among U.S.-born older Mexican Americans. Aim: This study aimed to test...
Fri Nov 01, 2019 02:00
Religions, Vol. 10, Pages 605: Social Cohesion in Australia: Comparing Church and Community Religions doi: 10.3390/rel10110605 Authors: Pepper Powell Bouma In a context of increasing ethnic and religious diversity, Australia’s future prosperity may depend, in part, on the ability to maintain social cohesion. Drawing on the framework developed by the Scanlon Foundation Social Cohesion Research Program, this study examines data from the 2016 National Church Life Survey...
Fri Nov 01, 2019 02:00
Risks, Vol. 7, Pages 111: High Frequency Price Change Spillovers in Bitcoin Markets Risks doi: 10.3390/risks7040111 Authors: Giudici Pagnottoni The study of connectedness is key to assess spillover effects and identify lead-lagrelationships among market exchanges trading the same asset. By means of an extension of Dieboldand Yilmaz (2012) econometric connectedness measures, we examined the relationships of five majorBitcoin exchange platforms during two periods of main interest:...
Fri Nov 01, 2019 02:00
Risks, Vol. 7, Pages 110: Quantitative and Comparative Analyses of Limit Order Books with General Compound Hawkes Processes Risks doi: 10.3390/risks7040110 Authors: Qiyue He Anatoliy Swishchuk In this paper, we solve the problem of mid price movements arising in high-frequency and algorithmic trading using real data. Namely, we introduce different new types of General Compound Hawkes Processes (GCHPDO, GCHP2SDO, GCHPnSDO) and find their diffusive limits to model the mid price movements...
Fri Nov 01, 2019 02:00
Sci, Vol. 1, Pages 63: Fall Risk in Older Adults Transitioning between Different Flooring Materials Sci doi: 10.3390/sci1030063 Authors: Hyung Nam Kim Thurmon E. Lockhart As there is lack of understanding about the effect of transitioning between different flooring materials on the gait of older adults, this study investigated the effect of transitioning between a carpeted floor and a vinyl floor on the gait characteristics of older adults. Fourteen older (65 years old and over) and...
Fri Nov 01, 2019 02:00
Sci. Pharm., Vol. 87, Pages 29: In Silico Mapping of Essential Residues in the Catalytic Domain of PDE5 Responsible for Stabilization of Its Commercial Inhibitors Scientia Pharmaceutica doi: 10.3390/scipharm87040029 Authors: Ivan Pires de Oliveira Caroline Honaiser Lescano Gilberto De Nucci Phosphodiesterase type 5 (PDE5) is an important enzyme associated with the hydrolysis of cyclic guanosine monophosphate (cGMP) to guanosine monophosphate (GMP). Due to the relevant role of second...
Fri Nov 01, 2019 02:00
Technologies, Vol. 7, Pages 79: Advanced Coatings by Thermal Spray Processes Technologies doi: 10.3390/technologies7040079 Authors: Joshi Nylen Coatings are pivotal in combating problems of premature component degradation in aggressive industrial environments and constitute a strategic area for continued development. Thermal spray (TS) coatings offer distinct advantages by combining versatility, cost-effectiveness, and the ability to coat complex geometries without constraints of...
Fri Nov 01, 2019 02:00
Toxins, Vol. 11, Pages 638: Total Dietary Intake and Health Risks Associated with Exposure to Aflatoxin B1, Ochratoxin A and Fuminisins of Children in Lao Cai Province, Vietnam Toxins doi: 10.3390/toxins11110638 Authors: Huong Tuyen Madsen Brimer Friis Dalsgaard The health burden of foodborne mycotoxins is considerable, but particularly for children due to their lower detoxification capacity, rapid growth and high intake of food in proportion to their weight. Through...
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Toxins, Vol. 11, Pages 636: Morphological and Transcriptomic Analysis of the Inhibitory Effects of Lactobacillus plantarum on Aspergillus flavus Growth and Aflatoxin Production Toxins doi: 10.3390/toxins11110636 Authors: Zhao Zhang Folly Chang Wang Zhou Zhang Liu Lactobacillus plantarum, as a natural bio-preservative, has attracted a great deal of attention in recent years. In this study, 22 L. plantarum strains were tested against the aflatoxin-producing...
Fri Nov 01, 2019 02:00
Toxins, Vol. 11, Pages 635: Elevation of Trimethylamine-N-Oxide in Chronic Kidney Disease: Contribution of Decreased Glomerular Filtration Rate Toxins doi: 10.3390/toxins11110635 Authors: Caroline C. Pelletier Mikael Croyal Lavinia Ene Audrey Aguesse Stephanie Billon-Crossouard Michel Krempf Sandrine Lemoine Fitsum Guebre-Egziabher Laurent Juillard Christophe O. Soulage Gut microbiota-dependent Trimethylamine-N-oxide (TMAO) has been reported to be strongly...
Fri Nov 01, 2019 02:00
Toxins, Vol. 11, Pages 637: Hadrurid Scorpion Toxins: Evolutionary Conservation and Selective Pressures Toxins doi: 10.3390/toxins11110637 Authors: Carlos E. Santibáñez-López Matthew R. Graham Prashant P. Sharma Ernesto Ortiz Lourival D. Possani Scorpion toxins are thought to have originated from ancestral housekeeping genes that underwent diversification and neofunctionalization, as a result of positive selection. Our understanding of the evolutionary origin of these peptides...
Fri Nov 01, 2019 02:00
TropicalMed, Vol. 4, Pages 134: Active Case Finding for Tuberculosis through TOUCH Agents in Selected High TB Burden Wards of Kolkata, India: A Mixed Methods Study on Outcomes and Implementation Challenges Tropical Medicine and Infectious Disease doi: 10.3390/tropicalmed4040134 Authors: Abhijit Dey Pruthu Thekkur Ayan Ghosh Tanusree Dasgupta Soumyajyoti Bandopadhyay Arista Lahiri Chidananda Sanju S V Milan K. Dinda Vivek Sharma Namita Dimari Dibyendu Chatterjee...
Fri Nov 01, 2019 02:00
TropicalMed, Vol. 4, Pages 135: Semi-Quantitative, Duplexed qPCR Assay for the Detection of Leishmania spp. Using Bisulphite Conversion Technology Tropical Medicine and Infectious Disease doi: 10.3390/tropicalmed4040135 Authors: Ineka Gow Douglas Millar John Ellis John Melki Damien Stark Leishmaniasis is caused by the flagellated protozoan Leishmania, and is a neglected tropical disease (NTD), as defined by the World Health Organisation (WHO). Bisulphite conversion technology...
Fri Nov 01, 2019 02:00
TropicalMed, Vol. 4, Pages 133: What Proportion of New Tuberculosis Patients Has a History of Household Tuberculosis Exposure? A Cross-Sectional Study from Udupi District, South India Tropical Medicine and Infectious Disease doi: 10.3390/tropicalmed4040133 Authors: Chidananda Sanju SV Nikhil Srinivasapura Venkateshmurthy Divya Nair Vrinda Hari Ankolekar Ajay MV Kumar While tuberculosis (TB) preventive therapy among household contacts is effective at an individual level, its...
Fri Nov 01, 2019 02:00
Vaccines, Vol. 7, Pages 171: Post-Glycosylation Modification of Sialic Acid and Its Role in Virus Pathogenesis Vaccines doi: 10.3390/vaccines7040171 Authors: Park Sialic acids are a family of nine carbon keto-aldononulosonic acids presented at the terminal ends of glycans on cellular membranes. α-Linked sialoglycoconjugates often undergo post-glycosylation modifications, among which O-acetylation of N-acetyl neuraminic acid (Neu5Ac) is the most common in mammalian cells. Isoforms...
Fri Nov 01, 2019 02:00
Vaccines, Vol. 7, Pages 169: Development of Universal Influenza Vaccines Targeting Conserved Viral Proteins Vaccines doi: 10.3390/vaccines7040169 Authors: Jazayeri Poh Vaccination is still the most efficient way to prevent an infection with influenza viruses. Nevertheless, existing commercial vaccines face serious limitations such as availability during epidemic outbreaks and their efficacy. Existing seasonal influenza vaccines mostly induce antibody responses to the surface proteins...
Fri Nov 01, 2019 02:00
Vaccines, Vol. 7, Pages 168: Vaccination against Paediatric Respiratory Pathogens Vaccines doi: 10.3390/vaccines7040168 Authors: Bianchini Argentiero Camilloni Silvestri Alunno Esposito Acute respiratory infections (ARIs) are extremely common in children, especially those under 5 years old. They can lead to complications, super-infection, respiratory failure, and even compromised respiratory function in adulthood. For some of the responsible pathogens, vaccines are...
Fri Nov 01, 2019 02:00
Vaccines, Vol. 7, Pages 170: A Recombinant La Sota Vaccine Strain Expressing Multiple Epitopes of Infectious Bronchitis Virus (IBV) Protects Specific Pathogen-Free (SPF) Chickens against IBV and NDV Challenges Vaccines doi: 10.3390/vaccines7040170 Authors: Tan Wen Qiu Yuan Meng Sun Liao Song Liu Shi Shao Ding Infectious bronchitis (IB) and Newcastle disease (ND) are two major infectious diseases that are a threat to the domestic poultry industry....
Fri Nov 01, 2019 02:00
Vaccines, Vol. 7, Pages 166: First-In-Human Trials of GamTBvac, a Recombinant Subunit Tuberculosis Vaccine Candidate: Safety and Immunogenicity Assessment Vaccines doi: 10.3390/vaccines7040166 Authors: Vasina Kleymenov Manuylov Mazunina Koptev Tukhovskaya Murashev Gintsburg Gushchin Tkachuk Tuberculosis is known to be the biggest global health problem, causing the most deaths by a single infectious agent. Vaccine-development efforts are extremely...
Fri Nov 01, 2019 02:00
Veterinary Sciences, Vol. 6, Pages 89: Purification and Characterisation of Badger IgA and Its Detection in the Context of Tuberculosis Veterinary Sciences doi: 10.3390/vetsci6040089 Authors: Deanna Dalley Sandrine Lesellier Francisco J. Salguero Mark A. Chambers European badgers are a wildlife reservoir of bovine tuberculosis in parts of Great Britain. Accurate diagnosis of tuberculosis in badgers is important for the development of strategies for the control of the disease....
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Viruses, Vol. 11, Pages 1017: Measles Encephalitis: Towards New Therapeutics Viruses doi: 10.3390/v11111017 Authors: Ferren Horvat Mathieu Measles remains a major cause of morbidity and mortality worldwide among vaccine preventable diseases. Recent decline in vaccination coverage resulted in re-emergence of measles outbreaks. Measles virus (MeV) infection causes an acute systemic disease, associated in certain cases with central nervous system (CNS) infection leading to lethal...
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Viruses, Vol. 11, Pages 1016: A Single Point Mutation in the Mumps V Protein Alters Targeting of the Cellular STAT Pathways Resulting in Virus Attenuation Viruses doi: 10.3390/v11111016 Authors: Malik Ngo Bosma Rubin Mumps virus (MuV) is a neurotropic non-segmented, negative-stranded, enveloped RNA virus in the Paramyxovirus family. The 15.4 kb genome encodes seven genes, including the V/P, which encodes, among other proteins, the V protein. The MuV V protein has been shown...
Fri Nov 01, 2019 02:00
Viruses, Vol. 11, Pages 1015: Emergence of Rare Bovine–Human Reassortant DS-1-Like Rotavirus A Strains with G8P[8] Genotype in Human Patients in the Czech Republic Viruses doi: 10.3390/v11111015 Authors: Moutelíková Sauer Dvořáková Heroldová Holá Prodělalová Group A Rotaviruses (RVA) are the leading cause of acute gastroenteritis in children and a major cause of childhood mortality in low-income countries. RVAs are mostly host-specific, but interspecies transmission...
Fri Nov 01, 2019 02:00
Viruses, Vol. 11, Pages 1014: No Evidence of Mosquito Involvement in the Transmission of Equine Hepacivirus (Flaviviridae) in an Epidemiological Survey of Austrian Horses Viruses doi: 10.3390/v11111014 Authors: Marcha Badenhorst Phebe de Heus Angelika Auer Till Rümenapf Birthe Tegtmeyer Jolanta Kolodziejek Norbert Nowotny Eike Steinmann Jessika-M.V. Cavalleri Prevalence studies have demonstrated a global distribution of equine hepacivirus (EqHV), a member of the...
Fri Nov 01, 2019 02:00
Viruses, Vol. 11, Pages 1012: HIV-1 Envelope Glycoprotein Amino Acids Signatures Associated with Clade B Transmitted/Founder and Recent Viruses Viruses doi: 10.3390/v11111012 Authors: Alexis Kafando Christine Martineau Mohamed El-Far Eric Fournier Florence Doualla-Bell Bouchra Serhir Adama Kazienga Mohamed Ndongo Sangaré Mohamed Sylla Annie Chamberland Hugues Charest Cécile L. Tremblay Background: HIV-1 transmitted/founder viruses (TF) are selected during...
Fri Nov 01, 2019 02:00
Viruses, Vol. 11, Pages 1013: The Role of Temperature in Transmission of Zoonotic Arboviruses Viruses doi: 10.3390/v11111013 Authors: Ciota Keyel We reviewed the literature on the role of temperature in transmission of zoonotic arboviruses. Vector competence is affected by both direct and indirect effects of temperature, and generally increases with increasing temperature, but results may vary by vector species, population, and viral strain. Temperature additionally has a significant...
Fri Nov 01, 2019 02:00
Water, Vol. 11, Pages 2296: Modeling and Dynamic-Simulating the Water Distribution of a Fixed Spray-Plate Sprinkler on a Lateral-Move Sprinkler Irrigation System Water doi: 10.3390/w11112296 Authors: Uniformity of water distribution plays an important role in evaluating irrigation quality. As necessities in calculating irrigation uniformity during designing a lateral-move sprinkler irrigation system (LMSIS), the water distribution patterns of individual sprinkler in motion are crucial....
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Water, Vol. 11, Pages 2294: A Feasibility Study of Wastewater Treatment Using Domestic Microalgae and Analysis of Biomass for Potential Applications Water doi: 10.3390/w11112294 Authors: Jeong-Mi Do Seung-Woo Jo Il-Sup Kim Ho Na Jae Hak Lee Han Soon Kim Ho-Sung Yoon Water scarcity and emerging demands for renewable energy have increased concerns about energy security and advanced wastewater treatment, and microalgae have emerged as promising candidates to solve these...
Fri Nov 01, 2019 02:00
Water, Vol. 11, Pages 2295: Fine Characterization of the Effects of Aquifer Heterogeneity on Solute Transport: A Numerical Sandbox Experiment Water doi: 10.3390/w11112295 Authors: Zhang Wu Hu Yeh Hao Lv Hydraulic conductivity (K) and the specific storage coefficient (S) are among the most important hydrogeological parameters of an aquifer. Traditionally, the hydrogeological parameters of a field aquifer system are mainly determined through a range of experiments...
Fri Nov 01, 2019 02:00
Water, Vol. 11, Pages 2293: Hydrochemical Characteristics, Controlling Factors, and Solute Sources of Streamflow and Groundwater in the Hei River Catchment, China Water doi: 10.3390/w11112293 Authors: Kou Li Hua Li Water scarcity in arid regions is exacerbated by water quality degradation from anthropogenic contamination. In water-scarce regions, it is crucial to identify hydrochemical characteristics and pollution sources for effective water resource management. In this...
Fri Nov 01, 2019 02:00
Water, Vol. 11, Pages 2292: Landslide Susceptibility Mapping Using GIS-Based Data Mining Algorithms Water doi: 10.3390/w11112292 Authors: Vali Vakhshoori Hamid Reza Pourghasemi Mohammad Zare Thomas Blaschke The aim of this study was to apply data mining algorithms to produce a landslide susceptibility map of the national-scale catchment called Bandar Torkaman in northern Iran. As it was impossible to directly use the advanced data mining methods due to the volume of data at...
Fri Nov 01, 2019 02:00
Water, Vol. 11, Pages 2291: Assessing the Impacts of Extreme Climate Events on Vegetation Activity in the North South Transect of Eastern China (NSTEC) Water doi: 10.3390/w11112291 Authors: Zhou Pei Xia Wu Zhong Wang Wang Cao Extreme climate events frequently exert serious effects on terrestrial vegetation activity. However, these effects are still uncertain in widely distributed areas with different climate zones. Transect analysis is important to understand...
Fri Nov 01, 2019 02:00
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