Abstract Blunt renal artery injury (BRAI) is a rare finding with incidence ranging from 0.05% to 0.08% among blunt abdominal trauma patients. BRAI occurs in 1% to 4% of patients with renal injury, and the most common cause is motor vehicle accidents. An unusual case of BRAI in a 47-year-old man at work is reported. The victim accidentally fell from a scaffold (approximately 3 m in height). He was transported to the hospital where he was intubated, but he died after 30 min despite...
Abstract Over 3 million cases of skin and soft tissue infections (SSTI) including cellulitis and abscesses are managed in U.S. emergency departments (EDs) each year.1‐4 Overlap in presentations of cellulitis and abscess, which require different therapeutic approaches, has prompted increasing research into point‐of‐care ultrasound (POCUS) to help differentiate the two.2,5,6
Abstract Objectives Survivors of acute cardiovascular disease events, such as acute coronary syndrome and stroke may experience significant psychological distress during and following the acute event. Long term adverse effects may follow, including the development of posttraumatic stress disorder (PTSD) and increased overall all‐cause mortality and recurrent cardiac events. The goal of this concepts paper is to describe and summarize the rates of adverse psychological outcomes, such as PTSD,...
Abstract 13R, a core gene of Andrias davidianus ranavirus (ADRV), encoded a protein containing a transmembrane domain (TMD) and a restriction endonuclease-like domain. However, the characterization and function of 13R and the protein it encodes remain unclear. In this study, Chinese giant salamander thymus cell (GSTC) was used to investigate the function of 13R. The results showed that the 13R transcripts were detected first at 8 h post-infection (hpi) by RT-PCR and the protein...
Abstract Cultivation of the castor crop is hindered by various factors and one of the approaches for genetic improvement of the crop is through exploitation of biotechnological tools. Response of castor tissues to in vitro culture is poor which necessitated this study on understanding the molecular basis of organogenesis in cultured tissues of castor, through de novo transcriptome analysis and by comparing with jatropha and sunflower having good regeneration ability. Transcriptome...
MacromoleculesDOI: 10.1021/acs.macromol.9b01526
MacromoleculesDOI: 10.1021/acs.macromol.9b01762
MacromoleculesDOI: 10.1021/acs.macromol.9b01777
BiomacromoleculesDOI: 10.1021/acs.biomac.9b01158
Journal of Natural ProductsDOI: 10.1021/acs.jnatprod.9b00567
Molecular PharmaceuticsDOI: 10.1021/acs.molpharmaceut.9b00945
Molecular PharmaceuticsDOI: 10.1021/acs.molpharmaceut.9b01046
Abstract WD-repeat (WDR) proteins are highly abundant and participate in a seemingly wide range of interactions and cellular functions acting as scaffolding molecules. However, WDR identification in potato has not been conducted so far. In this study, we demonstrated the presence of at least 168 WDR genes in potato (Solanum tuberosum L.) which can be subdivided into five discrete clusters (Cluster I–V) and 10 classes inferred from their phylogenetic features of the constituent...
Related Articles[Radicalization and psychiatry: a plea for a broad perspective]. Tijdschr Psychiatr. 2019;61(8):554-562 Authors: de Ridder B, Fassaert T, Grimbergen C Abstract BACKGROUND: The extent to which psychiatry can, and should, contribute to the prevention of terrorism and the countering of radicalization is under debate. The political dimension of the problem raises questions about the desirability of active psychiatric involvement.<br/>...
Related Articles[Reflecting on intramural incidents: how do judges think about intramural crimes in mental health care?] Tijdschr Psychiatr. 2019;61(8):536-543 Authors: Visscher AJE, Tonkens E, Braam AW Abstract BACKGROUND: Various measures aim to stimulate prosecution of violence and aggression against mental-health workers. Considering a possible increase of inpatient incidents through article 2.3 of the Bill Forensic Care, this is a desirable development....
Related ArticlesIn Vitro Metabolism of 25B-NBF, 2-(4-Bromo-2,5-Dimethoxyphenyl)-N-(2-Fluorobenzyl)ethanamine, in Human Hepatocytes Using Liquid Chromatography⁻Mass Spectrometry. Molecules. 2019 Feb 25;24(4): Authors: Kim JH, Kim S, Lee J, In S, Cho YY, Kang HC, Lee JY, Lee HS Abstract 25B-NBF, 2-(4-bromo-2,5-dimethoxyphenyl)-N-(2-fluorobenzyl)ethanamine, is a new psychoactive substance classified as a phenethylamine. It is a potent agonist of the 5-hydroxytryptamine...
Related ArticlesThe HNF1α-Regulated LncRNA HNF1α-AS1 Is Involved in the Regulation of Cytochrome P450 Expression in Human Liver Tissues and Huh7 Cells. J Pharmacol Exp Ther. 2019 03;368(3):353-362 Authors: Wang Y, Yan L, Liu J, Chen S, Liu G, Nie Y, Wang P, Yang W, Chen L, Zhong X, Han S, Zhang L Abstract Expression of cytochrome P450s (P450s) is regulated by epigenetic factors, such as DNA methylation, histone modifications, and noncoding RNAs through...
Related ArticlesAssociation of the drug of abuse in road traffic collision death in Hospital Kuala Lumpur. Med J Malaysia. 2018 10;73(5):272-275 Authors: Subramaniam K, Mohd Shah M, Fatin Farisha F, Poh SL, Nor Fadhilah M, Hilmi S Abstract INTRODUCTION: The role of pathologist not only confined in performing post mortem but also can assist in prevention. The aim of this study to determine the prevalence and association of drug of abuse (DoA) in road...
Related ArticlesGenetic polymorphisms of GZMB and vitiligo: A genetic association study based on Chinese Han population. Sci Rep. 2018 08 29;8(1):13001 Authors: Xu M, Liu Y, Liu Y, Li X, Chen G, Dong W, Xiao S Abstract Vitiligo is a skin disease that affects 1% of the population worldwide. Both environmental and genetic factors contribute to the risk of vitiligo. GZMB encodes the enzyme Granzyme B, which plays an important role in cytotoxic T cell-induced...
Abstract The phase-appropriate application of analytical methods to characterize, monitor, and control particles is an important aspect of the development of safe and efficacious biotherapeutics. The AAPS Product Attribute and Biological Consequences (PABC) focus group (which has since transformed into an AAPS community) conducted a survey where participating labs rated their method of choice to analyze protein aggregation/particle formation during the different stages of the...
MacromoleculesDOI: 10.1021/acs.macromol.9b01710
Chemical Research in ToxicologyDOI: 10.1021/acs.chemrestox.9b00236
Chemical Research in ToxicologyDOI: 10.1021/acs.chemrestox.9b00338
Chemical Research in ToxicologyDOI: 10.1021/acs.chemrestox.9b00332
Chemical Research in ToxicologyDOI: 10.1021/acs.chemrestox.9b00294
Journal of Natural ProductsDOI: 10.1021/acs.jnatprod.9b00512
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00415
Molecular PharmaceuticsDOI: 10.1021/acs.molpharmaceut.9b00861
Molecular PharmaceuticsDOI: 10.1021/acs.molpharmaceut.9b00855
Publication date: January 2020Source: Accident Analysis & Prevention, Volume 134Author(s): Yen-Chun Kuo, Lian-Yu Chen, Hu-Ming Chang, Tien-Wei Yang, Ming-Chyi Huang, Wan-Ju ChengAbstractBackgroundDriving/riding under the influence (DUI) of alcohol is a major public concern worldwide. Only a few studies have distinguished DUI-related variables between motorcyclists and car drivers. This study examined the differences in demographic characteristics and drinking behaviors among first-time DUI offenders...
Publication date: Available online 1 November 2019Source: Forensic Science InternationalAuthor(s): Frances A. Procter, Graeme T. Swindles, Natasha L.M. BarlowAbstract•Soil forensics has proven instrumental in assisting criminal investigation, and there is an increasing demand for experimental studies on such trace evidence. Here we present the first detailed study on the influence of clothing materials in soil transfer. We adopt an experimental approach to test the transfer of five common UK soils...
Publication date: Available online 1 November 2019Source: Forensic Science InternationalAuthor(s): Luciana Domingues Conceição, Alexandre S. Masotti, Andrew H. Forgie, Fábio Renato Manzolli LeiteAbstractIntroductionThe identification of aesthetic dental materials during clinical dental examination can be challenging especially as patients and dental manufacturers place great emphasis on filling materials being as close as possible in appearance to the natural tooth. This makes dental identification...
Publication date: Available online 31 October 2019Source: Forensic Science InternationalAuthor(s): Rubén Darío Diaz-Martin, Javier R. Ambrosio, Ricardo Mondragón Flores, Sirenia Gonzáles-Pozos, Lorena Valencia-CaballeroAbstractDue the proteins from bone remains are highly resistant to pass of time and environmental conditions, they could tell us about the events that probably happened in the past. In the forensic and physical anthropology context, burnt bone remains are one of the most common pieces...
Publication date: Available online 31 October 2019Source: Forensic Science InternationalAuthor(s): Burkhard Madea, Elke Doberentz, Christian JackowskiAbstractThe question whether an injury was sustained during life or not is one of the most important subjects in forensic medicine. Therefore, vital reactions have been a main research topic in forensic medicine for a long period and many renowned forensic pathologists have devoted important papers to this field. The research area ranges from macroscopically...
Publication date: Available online 1 November 2019Source: Acta BiomaterialiaAuthor(s): Jieni Fu, Xiangmei Liu, Lei Tan, Zhenduo Cui, Yanqin Liang, Zhaoyang Li, Shengli Zhu, Yufeng Zheng, Kelvin Wai Kwok Yeung, Paul K Chu, Shuilin WuAbstractGrowing evidence suggests that the physical microenvironment can guide cell fate. However, cells sense cues from the adjacent physical microenvironment over a limited distance. In the present study, murine mesenchymal stem cells (MSCs) and murine preosteoblastic...
Publication date: Available online 31 October 2019Source: Acta BiomaterialiaAuthor(s): Rahul Atmaramani, Bitan Chakraborty, Rashed T. Rihani, Joshua Usoro, Audrey Hammack, Justin Abbott, Patrick Nnoromele, Bryan J. Black, Joseph J. Pancrazio, Stuart F. CoganAbstractWe have characterized the in vitro and in vivo extracellular neural recording and stimulation properties of ruthenium oxide (RuOx) based microelectrodes. Cytotoxicity and functional neurotoxicity assays were carried out to confirm the...
Publication date: Available online 31 October 2019Source: Acta BiomaterialiaAuthor(s): L. Casarrubios, N. Gómez-Cerezo, S. Sánchez-Salcedo, M.J. Feito, M.C. Serrano, M. Saiz-Pardo, L. Ortega, D. de Pablo, I. Díaz-Güemes, B. Fernández-Tomé, S. Enciso, F.M. Sánchez-Margallo, M.T. Portolés, D. Arcos, M. Vallet-RegíAbstractSilicon-substituted hydroxyapatite (SiHA) macroporous scaffolds have been prepared by robocasting. In order to optimize their bone regeneration properties, we have manufactured these...
MacromoleculesDOI: 10.1021/acs.macromol.9b01942
Publication date: Available online 31 October 2019Source: Journal of Forensic and Legal MedicineAuthor(s): Clara-Sophie Schwarz, Katrin Uebbing, Tanja Germerott, Astrid KrauskopfAbstractA fatality of an 83-year-old female experiencing acute circulatory failure as a result of a type II odontoid fracture is compared with the case of an 86-year-old female who died from delayed cardiopulmonary complications due to a lower cervical spine injury. Falls on the forehead from minor height can cause odontoid...
Publication date: Available online 31 October 2019Source: Forensic Science International: GeneticsAuthor(s): Alexandra L. Emmons, Jonathan Davoren, Jennifer M. DeBruyn, Amy Z. MundorffAbstractOur ability to identify skeletal remains often relies on the quality and quantity of DNA extracted from bone and teeth. Current research on buried remains has been retrospective, and no study to our knowledge has comprehensively assessed both intra-individual and inter-individual variation in human skeletal...
Abstract Bladder cancer is the most common cancer of the urinary system and often presents with hematuria. Despite its relatively high incidence, bladder cancer is often under-recognized sonographically. Moreover, even when bladder abnormalities are identified, numerous other entities may mimic the appearance of bladder cancer. Given the incidence and prevalence of bladder cancer, it is important to recognize its variable appearance sonographically and distinguish it from its common...
Introduction: The Acibadem Health Group (AHG) has been using telepathology/digital pathology stations since 2006. In 2013, the system was changed from videoconferencing to digital pathology (whole-slide imaging) utilizing 3DHISTECH scanners and software. In 2017, digital cytology started to be used for routine cytopathologic diagnosis for thyroid fine-needle aspiration (FNA) cases. Material and Methods: Two hundred and twenty-seven thyroid cases were received for analysis using telecytology (TC)...
Publication date: Available online 31 October 2019Source: Archives of Oral BiologyAuthor(s): Marta Estela Saravia, Lea Assed Bezerra da Silva, Raquel Assed Bezerra da Silva, Norma Mercedes Cudmani, Silvina Tineo, Norma Elena Hillen, Marília Pacífico Lucisano, Alexandra Mussolino de Queiroz, Claes-Göran Emilson, Paulo Nelson-FilhoAbstractObjectivesThe objective of this study was to evaluate the efficiency of SB-20 M culture medium to perform differential morphological identification of S. mutans and...
Publication date: Available online 31 October 2019Source: Archives of Oral BiologyAuthor(s): A.J.M. Ligtenberg, M. Meuffels, E.C.I. VeermanAbstractObjectiveThe aim of this study is to evaluate the short term effects of environmental temperature on saliva flow rate and composition.MethodsIn a cross-over study design 20 subjects (18-25 years old, 14 women, 6 men) were exposed in randomized order at different days to three temperatures (4 °C, 21 °C and 37 °C). Five minutes after a subject was exposed...
Publication date: Available online 31 October 2019Source: Archives of Oral BiologyAuthor(s): Rabab Hassan, Amany A. Rabea, Alyaa Ragae, Dina SabryAbstractObjectiveTo elucidate the effect of Alzheimer’s disease on the structure of circumvallate papilla taste buds and the possible role of exosomes on the taste buds in Alzheimer’s disease.DesignForty two ovariectomized female adult albino rats were utilized and divided into: Group I: received vehicle. Group II: received aluminum chloride to induce Alzheimer’s...
International Journal of Offender Therapy and Comparative Criminology, Ahead of Print. To date, international comparisons of self-reported crime have been mostly limited to Western countries. The current study explores offending for large samples of university students in Malaysia (N = 2,058) and the United States (N = 2,511), and utilizes measures of social bond theory to test its predictive utility cross-nationally. The descriptive results reveal that for both males and females, offending rates...
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