Σάββατο 2 Νοεμβρίου 2019


piRNA-Guided CRISPR-like Immunity in Eukaryotes
Publication date: Available online 31 October 2019Source: Trends in ImmunologyAuthor(s): Youdiil Ophinni, Umberto Palatini, Yoshitake Hayashi, Nicholas F. ParrishEukaryotic genomes contain virus-derived sequences called endogenous virus elements (EVEs). The majority of EVEs are related to retroviruses, which integrate into the host genome in order to replicate. Some retroviral EVEs encode a function; for example, some produce proteins that block infection by related viruses. EVEs derived from nonretroviral...
ScienceDirect Publication Trends in Immunology
Fri Nov 01, 2019 19:27
Immune Networks and Therapeutic Targeting of iNKT Cells in Cancer
Publication date: Available online 31 October 2019Source: Trends in ImmunologyAuthor(s): Shin-Ichiro Fujii, Kanako ShimizuOne of the primary goals in tumor immunotherapy is to reset the immune system from tolerogenic to immunogenic – a process in which invariant natural killer T (iNKT) cells are implicated. iNKT cells develop in the thymus and perform immunosurveillance against tumor cells peripherally. When optimally stimulated, iNKT cells differentiate and display more efficient immune functions....
ScienceDirect Publication Trends in Immunology
Fri Nov 01, 2019 19:27

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