Publication date: Available online 1 November 2019Source: Otolaryngologic Clinics of North AmericaAuthor(s): Kwaku K. Ohemeng, Kourosh Parham
12:01
Publication date: Available online 1 November 2019Source: Otolaryngologic Clinics of North AmericaAuthor(s): Sujana S. Chandrasekhar
12:01
Publication date: Available online 1 November 2019Source: Otolaryngologic Clinics of North AmericaAuthor(s): Angela Zhu, Ahad A. Qureshi, Elliott Kozin, Daniel J. Lee
12:01
Publication date: Available online 1 November 2019Source: Otolaryngologic Clinics of North AmericaAuthor(s): Johanna L. Wickemeyer, Jeffrey D. Sharon, Heather M. Weinreich
12:01
Publication date: Available online 1 November 2019Source: Otolaryngologic Clinics of North AmericaAuthor(s): Eric H. Holbrook, Daniel H. Coelho
12:01
Publication date: Available online 31 October 2019Source: Otolaryngologic Clinics of North AmericaAuthor(s): James G. Naples, Michael J. Ruckenstein
Fri Nov 01, 2019 17:29
Publication date: Available online 31 October 2019Source: Otolaryngologic Clinics of North AmericaAuthor(s): Joost Johannes Antonius Stultiens, Alida Annechien Postma, Nils Guinand, Angélica Pérez Fornos, Hermanus Kingma, Raymond van de Berg
Fri Nov 01, 2019 17:29
Publication date: Available online 1 November 2019Source: Aggression and Violent BehaviorAuthor(s): Nadia S. AnsaryAbstractEmerging evidence has revealed that many characteristics of cyberbullying—its definition, prevalence rates, risk and protective factors, outcomes, and prevention strategies—are related and yet somewhat unique from traditional bullying. The ubiquity of technology in the lives of youth presents an opportunity for individuals to intentionally and repetitively harm others, 24 h per...
11:59
Publication date: Available online 31 October 2019Source: Aggression and Violent BehaviorAuthor(s): Wen-Chen Ouyang, Gwo-Ching Sun, Mei-Chi HsuAbstractSchizophrenia is a disabling neurological disorder. Patients with this disease are at higher risk to violence. This paper reviewed the recent literatures with respect to the heterogeneous nature of the abnormalities and pathophysiological and biological risk markers that link to violent behavior in patients with schizophrenia with a particular interest...
Fri Nov 01, 2019 17:46
CONCLUSION The PC utilization was very high for older trauma patients who died in hospital. In contrast, the majority of those who were discharged alive, but with poor outcomes, did not have PC. Development of triggers to identify older trauma patients, who would benefit from PC, could close this gap and improve quality of care and outcomes. (Source: The Journal of Trauma: Injury, Infection, and Critical Care)
Fri Nov 01, 2019 06:00
Conclusion Our personal experience indicated that chemotherapy might provide a survival benefit in SCLC patients with metastasis-induced pancreatitis, especially those with good performance status. (Source: Pancreas)
Fri Nov 01, 2019 06:00
AbstractChildren with single ventricle congenital heart defects (SVCHD) experience a significant risk of early mortality throughout their lifespan, particularly during their first year of life. Due to the intense care needed for these children and families, pediatric palliative care (PPC) team consults should be routine; however, medical staff are often reluctant to broach the idea of PPC to families. The involvement of PPC for many carries with it an association to end-of-life (EOL) care. Setting...
Fri Nov 01, 2019 00:00
CONCLUSION: Timely EOL communication between caregivers and the providers is key to the patient's optimal transition to hospice care. Providers need to be aware of the caregivers' informational needs relating to patient symptoms and health condition as well as hospice care. It is important to be aware of the impact of cultural values on hospice care placement. A clear explanation about the purpose and functions of hospice care and its benefit can better guide the family caregivers in making hospice...
Wed Oct 30, 2019 00:00
"Farewell" to Prognosis in Shared Decision-Making. Am J Hosp Palliat Care. 2019 Oct 30;:1049909119885323 Authors: Johnson RF Abstract Whether because of a cultural pattern or personal preference, palliative care clinicians encounter persons approaching the end of life who wish to limit or forego prognostic information relating to their situation. This scenario has received attention in a recent motion picture as well as a newly available advance directive modification-the...
Wed Oct 30, 2019 00:00
Authors: Hilal T PMID: 31665899 [PubMed - as supplied by publisher] (Source: The American Journal of Hospice and Palliative Care)
Wed Oct 30, 2019 00:00
ConclusionParticipants perceived that social disparities may increase symptom complexity in populations with advanced cancer. Participants did not identify ethnicity and gender as influencing symptom burden. Further research is needed to examine the interactions of social disparities, patient individuality, and symptom burden. (Source: Supportive Care in Cancer)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
Fri Nov 01, 2019 13:38
Malignant fungating wounds present in 5–14% of advanced cancer patients in the United States and are a result of cancerous cells infiltrating and proliferating in the skin. Presentation of malignant fungating wounds often occurs in the last 6 months of life and therefore become symbols of impending death for patients and their families. Due to the incurable and severe nature of these wounds, patients require palliative care until death to minimize pain and suffering. Symptoms associated with these...
Fri Nov 01, 2019 00:00
Domains other than those commonly measured (physical, psychological, social, and sometimes existential/spiritual) are important to the quality of life of people with life-threatening illness. The McGill Quality o... (Source: BMC Palliative Care)MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.
Thu Oct 31, 2019 01:00
Internationally there is an increasing concern about the quality of end-of-life care (EoLC) provided in acute hospitals. More people are cared for at end of life and die in acute hospitals than in any other he... (Source: BMC Palliative Care)
Thu Oct 31, 2019 01:00
General Practitioners (GPs) often play an important role in caring for people at the end of life. While some international studies suggest that GPs experience a number of barriers to providing palliative care,... (Source: BMC Palliative Care)
Thu Oct 31, 2019 01:00
Conflict is frequently reported by both clinicians and surrogate decision-makers for adult patients in intensive care units (ICUs). Since religious clinicians view religion as an important dimension of end-of-life care, we hypothesized that religious critical care attendings (intensivists) would be more comfortable and perceive less conflict when discussing a patient ’s critical illness with a religious surrogate (12). (Source: Journal of Pain and Symptom Management)
Thu Oct 31, 2019 00:00
Opioids are prescribed to manage moderate to severe pain and can be used with older adults; however, they may lead to several adverse effects, including cognitive impairment. (Source: Journal of Pain and Symptom Management)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
Thu Oct 31, 2019 00:00
Despite complex illness trajectories and a high symptom burden, palliative care has been sub-optimal for patients with end-stage kidney disease and hemodialysis treatment who have a high rate of hospitalizatio... (Source: BMC Palliative Care)
Wed Oct 30, 2019 01:00
Breathlessness is associated with depression, but its relationship to anxiety or impaired function is less clear. (Source: Journal of Pain and Symptom Management)
Tue Oct 22, 2019 00:00
Tufts University researchers have transplanted engineered pancreatic beta cells into diabetic mice, then caused the cells to produce more than two to three times the typical level of insulin by exposing them to light. The light-switchable cells are designed to compensate for the lower insulin production or reduced insulin response found in diabetic individuals. The study published in ACS Synthetic Biology shows that glucose levels can be controlled in a mouse model of diabetes without pharmacological...
11:55
How variable are gene transcripts and proteins, the molecules of life, across the tissues and organs of the human body? Furthermore, how variable are they within the same tissue type from different people? Understanding this variability will be key for the realization of personalized medicine. These questions are the focus of a new study led by researchers from Uppsala University, which is published in NAR Genomics and Bioinformatics.
Fri Nov 01, 2019 16:40
Researchers at TU Delft have succeeded in replicating a biological mechanism that is essential for cell division in bacteria in the lab. The research is an important step within a larger project with the ultimate goal of creating a fully artificial cell that can sustain and divide itself. The researchers have published their findings in Nature Communications.
Fri Nov 01, 2019 14:49
In temperate latitudes, the right timing is crucial for almost all living things: Plants sprout with the advent of spring, bees know the best times to visit flowers, people get tired in the evening and wake up again in the morning. The constant change between light and dark is the rhythm to which all living beings must adapt if they want to survive and reproduce. Circadian clocks regulate the timekeeping mechanism in each organism and adjust it to changes.
Fri Nov 01, 2019 13:51
Can scrambled eggs unscramble themselves? Well, sort of.
Fri Nov 01, 2019 13:50
One-third of all approved drugs target the same family of receptors: the G-protein-coupled receptors (GPCRs). Now, researchers from the University of Copenhagen, along with two American labs, have expanded the known network of peptides that activate GPCRs by 19 percent.
Fri Nov 01, 2019 13:49
JCM, Vol. 8, Pages 1850: Mitotane Concentrations Influence the Risk of Recurrence in Adrenocortical Carcinoma Patients on Adjuvant Treatment Journal of Clinical Medicine doi: 10.3390/jcm8111850 Authors: Soraya Puglisi Anna Calabrese Vittoria Basile Filippo Ceccato Carla Scaroni Chiara Simeoli Massimo Torlontano Salvatore Cannavò Giorgio Arnaldi Antonio Stigliano Pasqualino Malandrino Laura Saba Barbara Altieri Silvia Della Casa Paola Perotti Paola...
02:00
JCM, Vol. 8, Pages 1847: Development of Oxadiazole-Based ODZ10117 as a Small-Molecule Inhibitor of STAT3 for Targeted Cancer Therapy Journal of Clinical Medicine doi: 10.3390/jcm8111847 Authors: Kim Lee Song Park Gadhe Choi Lee Pae Kim Ye Persistently activated STAT3 is a promising target for a new class of anticancer drug development and cancer therapy, as it is associated with tumor initiation, progression, malignancy, drug resistance, cancer stem...
02:00
JCM, Vol. 8, Pages 1849: Pink1-Mediated Chondrocytic Mitophagy Contributes to Cartilage Degeneration in Osteoarthritis Journal of Clinical Medicine doi: 10.3390/jcm8111849 Authors: Hyo Jung Shin Hyewon Park Nara Shin Hyeok Hee Kwon Yuhua Yin Jeong-Ah Hwang Hee-Jung Song Jinhyun Kim Dong Woon Kim Jaewon Beom Cartilage loss is a central event in the pathogenesis of osteoarthritis (OA), though other than mechanical loading, the biochemical mechanisms underlying...
02:00
JCM, Vol. 8, Pages 1845: Effectiveness of Chronic Wound Debridement with the Use of Larvae of Lucilia Sericata Journal of Clinical Medicine doi: 10.3390/jcm8111845 Authors: Dariusz Bazaliński Maria Kózka Magdalena Karnas Paweł Więch The process of successful wound healing depends on effective debridement and infection control. One method of wound debridement, known since antiquity, is based on the use of fly larvae. Solid scientific evidence proves that maggot debridement therapy...
02:00
JCM, Vol. 8, Pages 1846: Targeting Endotypic Traits with Medications for the Pharmacological Treatment of Obstructive Sleep Apnea. A Review of the Current Literature Journal of Clinical Medicine doi: 10.3390/jcm8111846 Authors: Taranto-Montemurro Messineo Wellman Obstructive sleep apnea (OSA) is a highly prevalent condition with few therapeutic options. To date there is no approved pharmacotherapy for this disorder, but several attempts have been made in the past and are currently...
02:00
JCM, Vol. 8, Pages 1844: Sarcopenia in Older Adults Journal of Clinical Medicine doi: 10.3390/jcm8111844 Authors: David Scott Sarcopenia was first described in 1988 as the age-related decline of skeletal muscle mass [...]
02:00
JCM, Vol. 8, Pages 1843: Gastrointestinal Microbiota and Type 1 Diabetes Mellitus: The State of Art Journal of Clinical Medicine doi: 10.3390/jcm8111843 Authors: Marilena Durazzo Arianna Ferro Gabriella Gruden The incidence of autoimmune type 1 diabetes (T1DM) is increasing worldwide and disease onset tends to occur at a younger age. Unfortunately, clinical trials aiming to detect predictive factors of disease, in individuals with a high risk of T1DM, reported negative results....
02:00
JCM, Vol. 8, Pages 1842: Investigation of the Correlation between Graves’ Ophthalmopathy and CTLA4 Gene Polymorphism Journal of Clinical Medicine doi: 10.3390/jcm8111842 Authors: Ding-Ping Chen Yen-Chang Chu Ying-Hao Wen Wei-Tzu Lin Ai-Ling Hour Wei-Ting Wang Graves’ disease (GD) is an autoimmune inflammatory disease, and Graves’ ophthalmopathy (GO) occurs in 25–50% of patients with GD. Several susceptible genes were identified to be associated...
02:00
JCM, Vol. 8, Pages 1841: Usefulness of Liquid Biopsy Biomarkers from Aqueous Humor in Predicting Anti-VEGF Response in Diabetic Macular Edema: Results of a Pilot Study Journal of Clinical Medicine doi: 10.3390/jcm8111841 Authors: Patricia Udaondo Cristina Hernández Laura Briansó-Llort Salvador García-Delpech Olga Simó-Servat Rafael Simó The objective was to investigate the usefulness of the “liquid biopsy” of aqueous humor (AH) to predict the clinical...
02:00
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου