Single-Cell Functional Proteomics Accelerates Immunotherapy Development,

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Introduction to Cell Therapy: CAR-T therapies have transformed Immunotherapy CAR-T therapies have quickly shifted the direction of treatments for aggressive diseases, such as blood cancers, where previous treatments were limited. There are currently over 1000 cell and gene therapy trials and two approved cell therapies, Axicabtagene ciloleucel and Tisagenlecleucel, but determining cellular fitness is still a top need in moving the next generation of cell therapy treatments forward.  Read More Introduction to Checkpoint Therapy: An Overview and Analysis Checkpoint immunotherapy development continues to grow at an incredible rate—as of 2018 there were more than 2250 clinical immunotherapy trials incorporating checkpoint therapy, with two of the three largest selling oncology drugs being checkpoint-based immunotherapies. As this field becomes even more cutting-edge, immuno-oncology trials have become much more complex, combining inhibitors with a variety of small molecules, agonists, vaccines, and multiple checkpoint therapies.  Read More The IsoPlexis Three-Step Single Cell Proteomics Workflow View Infographic A Power Tool for Immune Profiling: Single-Cell Functional Proteomics Many companies are racing to develop cancer immunotherapies—a market estimated to be worth $50 billion and expected to grow exponentially over the next several years. Some of the earliest such approved products have shown great promise, but one of the challenges to overcome is that these therapies have had mixed results in a limited number of patients.  Read More

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