Authors: Saw Bawm, Tay Zar Bhone Win, Shwe Yee Win, Lat Lat Htun, Ryo Nakao and Ken Katakura.Parasite Vol. 27 , page 38Published online: 19/05/2020 Keywords: Eimeria arloingi ; Eimeria hirci ; Eimeria christenseni ; Domesticated goats ; Myanmar.
Tue May 19, 2020 03:00
Authors: František Moravec and Jean-Lou Justine.Parasite Vol. 27 , page 37Published online: 19/05/2020 Keywords: Nematode parasite ; Seuratoidea ; Mugiliformes ; Perciformes ; Tetraodontiformes ; South Pacific.
Tue May 19, 2020 03:00
Authors: Michel Boussinesq, Peter Enyong, Patrick Chounna-Ndongmo, Abdel-Jelil Njouendou, Sébastien David Pion, Anthony Rech, Christophe Roberge, Georges Gaudriault and Samuel Wanji.Parasite Vol. 27 , page 36Published online: 18/05/2020 Keywords: Onchocerciasis ; Onchocerca ochengi ; Ivermectin ; Long-acting formulation ; Microfilaricidal effect ; Macrofilaricidal effect.
Mon May 18, 2020 03:00
Authors: Zi-Hua Zhou, You-Zhi Li, Lin Liu, Xue-Juan Ding and Kai Yuan.Parasite Vol. 27 , page 33Published online: 15/05/2020 Keywords: Monogenea ; Microcotylidae ; Paracaesicola nanshaensis n. gen. n. sp. ; Paracaesio sordida ; The South China Sea.
Fri May 15, 2020 03:00
Authors: Junqiang Li, Yueyue Yuan, Yuxi Jiang, Wen Wang, Liqin Chao, Ruiqin Sun, Jun Li, Md Robiul Karim and Meng Qi.Parasite Vol. 27 , page 35Published online: 15/05/2020 Keywords: Blastocystis sp. ; Identification ; Subtype ; Laboratory rats.
Fri May 15, 2020 03:00
Authors: Vivek Bhakta Mathema, Supatchara Nakeesathit, Nicholas J. White, Arjen M. Dondorp and Mallika Imwong.Parasite Vol. 27 , page 34Published online: 15/05/2020 Keywords: Tandem repeats ; Gene ontology ; Microsatellite markers ; Malaria.
Fri May 15, 2020 03:00
On December 31, 2019, China reported a cluster of pneumonia cases of unknown cause that would later be identified as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Patients with the illness, called coronavirus disease 2019 (Covid-19), frequently present with fever, cough, and…
03:00
Abstract Sialodochitis fibrinosa (also known as Kussmaul disease) was originally described by Kussmaul in 1879. This condition involves recurrent parotid grand swelling and mucus plugs containing leukocytes and Charcot–Leyden crystals (CLCs) (Ray et al., 2015) (Baer et al., 2017) (Flores et al., 2016). Sialodochitis fibrinosa also includes recurrent salivary gland swelling with fibrinous eosinophil‐rich mucus plugs. Although the disease is relatively rare, a recent review of Japanese and English...
Wed May 20, 2020 21:40
The hetero‐arylation of alkenes with aryl iodides has been efficiently achieved with the (MeDalphos)AuCl complex via Au(I)/Au(III) catalysis. The possibility to combine oxidative addition of aryl iodides and π‐activation of alkenes at gold is demonstrated for the first time. The reaction is robust and general (>30 examples including internal alkenes, 5, 6 and 7‐membered rings). It is regioselective and leads exclusively to trans addition products. The (P,N) gold complex is most efficient with...
10:26
It has been long‐pursued but remains great challenge to precisely manipulate the molecule assembly process to have desired functional structures. Here, we report such a control over the assembly of solute molecules, via a programmed recrystallization of solvent crystal grains, to form micro/nano‐ particles with tunable sizes and crystalline forms. A quantitative correlation between the protocol of recrystallization temperature and the assembly kinetics results in the precise control over the size...
Wed May 20, 2020 13:19
Light makes a difference : An unprecedented photoredox‐controlled regioselective radical inverse hydroboration (compared with ionic hydroboration) of α,β‐unsaturated amides with NHC‐BH3 has been developed. This protocol provides a general and convenient route to construct a wide range of structurally diverse β‐borylated amides in synthetically useful yields under mild conditions. Abstract In this Communication, we report an unprecedented β‐regioselective radical inverse hydroboration (compared...
Wed May 20, 2020 11:34
The completely stereoselective assembly of fungal Aspergillus fumigatus galactosaminogalactans, incorporating α‐Gal, α‐GalN and α‐GalNac residues up to dodecasaccharides, is reported. Structural studies reveal a non‐canonical C−H⋅⋅⋅O hydrogen bond to stabilize the elongated, linear structure that displays the Gal‐functional groups to the outside of the polymer, available for interactions with binding partners. Abstract Galactosaminogalactan (GAG) is a prominent cell wall component of the...
Wed May 20, 2020 11:32
The DNA Code : A novel steganography and cryptography molecular information coding (MIC) strategy in a reconfigurable DNA origami domino array (DODA) is demonstrated. This strategy opens new opportunities for high‐density information storage and information security against decoding, duplication, and forgery, overcoming the key difficulties in MIC technologies. Abstract DNA nanostructures with programmable nanoscale patterns has been achieved in the past decades, and molecular information coding...
Wed May 20, 2020 11:32
Supercharged : The in situ pyrolysis and real‐time progressive phase evolution of a binary zinc molecular cluster are tracked. The supercapacitive porous carbon, which is obtained under 900 °C, has a record capacitance of 662 F g−1 at 0.5 A g−1. Abstract The in situ tracking of the pyrolysis of a binary molecular cluster [Zn7(μ3‐CH3O)6(L)6][ZnLCl2]2 is presented with one brucite disk and two mononuclear fragments (L=mmimp: 2‐methoxy‐6‐((methylimino)‐methyl)phenolate) to porous carbon using...
Wed May 20, 2020 11:30
Analysis of the substrate binding mode of amino‐steroids to a supramolecular catalyst enables rational prediction of site selectivity in C(sp3)−H oxidation of amino‐steroids. This strategy was applied to late‐stage C(sp3)−H oxidation of amino‐steroids at C15 (or C16), with a selectivity tunable by modification of the catalyst chirality and metal. Abstract Predictability is a key requirement to encompass late‐stage C−H functionalization in synthetic routes. However, prediction (and control)...
Wed May 20, 2020 11:29
Stable narrow‐band green emitter : Dual‐shelled moisture‐resistant RbLi(Li3SiO4)2:Eu2+@Al2O3@ODTMS, is prepared in two steps. Atomic layer deposition (ALD) coats alumina on the surface of RbLi(Li3SiO4)2:Eu2+. Then the surface is modified with ODTMS to make it hydrophobic giving a composite phosphor with good moisture stability, which is crucial for commercial LED applications. Abstract The stability of luminescent materials is a key factor for the practical application in white light‐emitting...
Wed May 20, 2020 11:28
That couple has great chemistry : A chemical ligation of peptides with C‐terminal salicylaldehyde esters to peptides with N‐terminal cysteine/penicillamine was developed. This method shows tolerance of steric hinderance from the side groups on either ligating terminus, thereby allowing flexible disconnection at sites that are otherwise difficult. This method can also be expanded to selective desulfurization and one‐pot ligation/desulfurization reactions. Abstract The chemical ligation of two...
Wed May 20, 2020 11:24
Close encounters : Carbon nanodots have been functionalized with phthalocyanine chromophores by a covalent synthetic approach. This approach made possible the formation of symmetry‐breaking charge transfer/separation states between two or more chromophore units connected on the carbon dot surface. Abstract Carbon dots (CDs) and their derivatives are useful platforms for studying electron‐donor/acceptor interactions and dynamics therein. Herein, we couple amorphous CDs with phthalocyanines (Pcs)...
Wed May 20, 2020 11:24
Harvest home : Through‐bond energy transfer (TBET) strategy was employed to construct a low‐cost copper(I) photosensitizer (PS) with high visible‐light harvesting ability and a long‐lived excited state. For energy‐ and electron‐transfer reactions it dramatically outperforms that of traditional Cu‐PS and noble‐metal PSs (Ru(bpy)32+ and Ir(ppy)3+). Abstract Developing strong visible‐light‐absorbing (SVLA) earth‐abundant photosensitizers (PSs) for significantly improving the utilization of solar...
Wed May 20, 2020 11:22
The right location : Solubilization location in micelles is accurately measured by FRET between anchored AIE donors and solubilized substances. In comparison with the current polarity‐based strategies, this method is independent of micellar polarities. Abstract Solubilization locations play a critical role in developing advanced surfactants and improving solubilization power in micelle‐based applications. However, the current polarity‐based techniques for measuring solubilization locations...
Wed May 20, 2020 11:22
Two sites are better than one : A redox mechanism with dual metal active site was found for the water‐gas shift (WGS) reaction on the Ir1/FeOx single‐atom catalyst by theoretical and experimental studies. The Ir1 and Fe atoms jointly facilitate the creation of an oxygen vacancy at the Fe species neighbouring the Ir1 atom, leading to sequential production of CO2 and H2. Abstract Herein, we report a theoretical and experimental study of the water‐gas shift (WGS) reaction on Ir1/FeOx single‐atom...
Wed May 20, 2020 11:21
Polymeric carbon nitride modified with selected heteroatom dopants in a cyclic melon was prepared and used as a model photocatalyst to identify and understand the key mechanisms required for efficient photoproduction of H 2 O 2 via selective oxygen reduction reaction (ORR). The photochemical production of H 2 O 2 was achieved at a millimolar level per hour under visible light irradiation along with 100% apparent quantum yield (in 360‐450 nm region) and 96% selectivity in an electrochemical...
Wed May 20, 2020 11:08
A cyclophane incorporating two units of a heptagon‐containing extended polycyclic aromatic hydrocarbon (PAH), analogue of the hexa‐ peri ‐hexabenzocoronene (HBC) moiety (hept‐HBC), is reported. This cyclophane represents a new class of macrocyclic structures that incorporate for the first time seven‐membered rings within extended PAH frameworks. The saddle curvature of the hept‐HBC macrocycle units induced by the presence of the non‐hexagonal ring along with the flexible alkyl linkers generate...
Tue May 19, 2020 22:04
The heteroleptic dirhodium paddlewheel catalyst 7 with a chiral carboxylate/acetamidate ligand sphere is uniquely effective in asymmetric [2+1] cycloadditions with a‐diazo‐a‐trimethylstannyl (silyl, germyl) acetate. Originally discovered as a trace impurity in a sample of the homoleptic parent complex [Rh 2 (( R )‐TPCP) 4 ] ( 5 ), it is shown that the protic acetamidate ligand is quintessential for rendering 7 highly enantioselective. The –NH group is thought to lock the ensuing metal...
Tue May 19, 2020 22:00
Eukaryotic cell shapes are determined by the cytoskeleton associating to membrane proteins, however, the detailed mechanism of how the integral morphologies with structural stability is generated and maintained is still not fully understood. Here, based on the Frame‐Guided Assembly (FGA) strategy, we successfully prepared hetero‐liposomes with similar structural composition to eukaryotic cells by screening a series of transmembrane peptides as the leading hydrophobic groups (LHGs). It was demonstrated...
Tue May 19, 2020 20:42
Targeted protein degradation (TPD), the ability to control a proteins fate by triggering its degradation in a highly selective and effective manner, has created tremendous excitement in chemical biology and drug discovery within the past decades. The TPD field is spearheaded by small molecule induced protein degradation with molecular glues and proteolysis targeting chimeras (PROTACs) paving the way to expand the druggable space and to create a new paradigm in drug discovery. However, besides the...
Tue May 19, 2020 20:10
The impact of a reactant from the gas phase on the surface of a liquid and its transfer through this gas/liquid interface are crucial for various concepts applying ionic liquids (ILs) in catalysis. We investigated the first step of the adsorption dynamics of n‐butane on a series of 1‐alkyl‐3‐methylimidazolium bis(trifluoromethanesulfonyl)imide ILs ([C n C 1 Im][Tf 2 N]; n = 1, 2, 3, 8). Using a supersonic molecular beam in ultra‐high vacuum, the trapping of n‑butane on the frozen ILs was determined...
Tue May 19, 2020 19:11
In this work, we demonstrated a simple random ternary copolymerization strategy to synthesize a series of polymer acceptors PTPBT‐ET x by polymerizing a small molecule acceptor unit modified from Y6 with thiophene connecting unit and controlled amount of 3‐ethylesterthiophene (ET) unit. Compared PTPBT of only Y6‐like units and thiophene units, PTPBT‐ET x (where x represents the molar ratio of ET unit) with incorporating ET unit in the ternary copolymers show up‐shifted LUMO energy level, increased...
Tue May 19, 2020 17:42
A practically useful method for the formation of the highly oxygenated bicyclo[3.2.1]octane ring system by Mn(OAc) 3 ‐mediated radical cyclization of alkynyl ketones has been developed, which opens up a new avenue to the total synthesis of a number of highly oxidized diterpenoids. Application of this method allows the first total synthesis of (−)‐glaucocalyxin A. Other salient features of the synthesis include a highly enantioselective conjugate addition/ acylation cascade reaction, a Yamamoto...
Tue May 19, 2020 17:41
Vacancy engineering has been proved repeatedly as an adoptable strategy to boost electrocatalysis, while its poor selectivity restricts the usage in nitrogen reduction reaction (NRR) as overwhelming competition from hydrogen evolution reaction (HER). Revealed by density functional theory calculations, the selenium vacancy in ReSe 2 crystal can enhance its electroactivity for both NRR and HER by shifting the d ‐band from ‐2.91 to ‐2.33 eV. To restrict the HER, we report a novel method by burying...
Tue May 19, 2020 17:41
The combination of more than one bioactive moiety in a mulitargeted anticancer agent may result in synergistic activity of its components. Using this concept, bioorganometallic compounds were designed to feature a metal center, a 2‐pyridinecarbothioamide (PCA), and a hydroxamic acid, which is found in the anticancer drug vorinostat (SAHA). The organometallics showed inhibitory activity in the nanomolar range against histone deacetylases (HDACs) as the key target for SAHA. In particular, Rh complex...
Tue May 19, 2020 17:39
Cancer nanovaccines that use nanomaterials as antigens and/or adjuvant‐delivering carriers can induce tumor antigen‐specific T cell immunity and have shown potential as therapeutic modalities in in vivo animal models. Moreover, the addition of immune checkpoint blockade (ICB) immunotherapy to cancer nanovaccines can further potentiate the antitumor efficacy of the latter. However, little effort has been made to develop an optimal treatment regimen based on treatment sequence and the timing of each...
Tue May 19, 2020 16:39
Buckyballs (Fullerenes) were first reported over 30 years ago, but still little is known regarding their natural occurrence, as they were only found at sites of high energy incidents, such as lightning strikes or meteor impacts but not reported in low energy materials like fossil fuels. Here, using ultrahigh‐resolution mass spectrometry, a wide range of Fullerenes from C 20 to C 114 was detected in an asphaltene fraction of a heavy crude oil, together with their building blocks of C 10n H ...
Tue May 19, 2020 16:10
In lithium metal batteries, electrolytes containing high‐concentration salts have demonstrated promising cyclability, but their practicality with respect to the cost of materials is yet to be warranted. Here we report a fluorinated aromatic compound, namely 1,2‐difluorobenzene, for use as a diluent solvent in the electrolyte to realize the “high‐concentration effect”. The low lowest unoccupied molecular orbital (LUMO) level, weak binding affinity for lithium ions, and high fluorine‐donating power...
Tue May 19, 2020 15:38
Stable operation at elevated temperature is necessary for lithium (Li) metal anode as the promising anode for next‐generation batteries in diversified scenarios. However, Li metal anode generally undergoes poor performances and even safety concerns at high temperature (> 55°C) due to the thermal instability of electrolyte and solid electrolyte interphase in a routine liquid electrolyte. Herein a Li metal anode working at an elevated temperature of 90°C is demonstrated in a thermal‐stable electrolyte....
Tue May 19, 2020 14:40
The first dinuclear Au(I) compounds containing bridging (CF 2 ) n chains (n = 4, 6, 8) and Au(III) metallaperfluorocyclopentanes have been obtained by photoinitiated reactions of LAuMe (L = PPh 3 , PMe 3 , PCy 3 or IPr) with α,ω‐diiodoperfluorocarbons. Complexes LAu(CF 2 ) 4 AuL present an unusual looped structure stabilized by an aurophilic interaction for L = PMe 3 , PPh 3 and PCy 3 . The study of their dynamic behaviour has provided new insights about the strength of aurophilic...
Tue May 19, 2020 14:10
Toroids and helices are fundamental geometrical structures in nature. Polymers can self‐assemble into various nanostructures, including both toroids and helices; however, nanostructures combining toroidal and helical morphologies, i.e., helical toroids, are rarely observed. Herein, we report that a binary system containing polypeptide homopolymer and its block copolymer can hierarchically self‐assemble into uniform helical nanotoroids in solution. The formation of the helical toroids is a successive...
Tue May 19, 2020 11:10
The world has faced various pandemics in the past, but COVID-19 is distinct from the previous ones. Rapidly, it has become the major global concern, causing more than 290,000 deaths—a number that continues to rise. While the world was not ready to prevent or combat the disease, respective countries took some measures to face it as quickly as possible. The pandemic has connected countries across the globe, but the response to it is diverse—largely determined by state boundaries and cultural implications....
Wed May 20, 2020 22:30
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