IJMS, Vol. 21, Pages 3612: What Do We Know About the Genetic Basis of Seed Desiccation Tolerance and Longevity? International Journal of Molecular Sciences doi: 10.3390/ijms21103612 Authors: Kijak Ratajczak Long-term seed storage is important for protecting both economic interests and biodiversity. The extraordinary properties of seeds allow us to store them in the right conditions for years. However, not all types of seeds are resilient, and some do not tolerate extreme desiccation...
Wed May 20, 2020 03:00
IJMS, Vol. 21, Pages 3611: Multiplatform Investigation of Plasma and Tissue Lipid Signatures of Breast Cancer Using Mass Spectrometry Tools International Journal of Molecular Sciences doi: 10.3390/ijms21103611 Authors: Alex Ap. Rosini Silva Marcella R. Cardoso Luciana Montes Resende John Q. Lin Fernando Guimaraes Geisilene R. Paiva Silva Michael Murgu Denise Gonçalves Priolli Marcos N. Eberlin Alessandra Tata Livia S. Eberlin Sophie F. M. Derchain Andreia...
Wed May 20, 2020 03:00
IJMS, Vol. 21, Pages 3610: Mir-370-3p Impairs Glioblastoma Stem-Like Cell Malignancy Regulating a Complex Interplay between HMGA2/HIF1A and the Oncogenic Long Non-Coding RNA (lncRNA) NEAT1 International Journal of Molecular Sciences doi: 10.3390/ijms21103610 Authors: Lulli Buccarelli Ilari Castellani De Dominicis Di Giamberardino D′Alessandris Giannetti Martini Stumpo Boe De Luca Biffoni Marziali Pallini Ricci-Vitiani Glioblastoma...
Wed May 20, 2020 03:00
IJMS, Vol. 21, Pages 3609: Early Reactive A1 Astrocytes Induction by the Neurotoxin 3-Nitropropionic Acid in Rat Brain International Journal of Molecular Sciences doi: 10.3390/ijms21103609 Authors: Lopez-Sanchez Garcia-Martinez Poejo Garcia-Lopez Salazar Gutierrez-Merino 3-Nitropropionic acid (NPA) administration to rodents produces degeneration of the striatum, accompanied by neurological disturbances that mimic Huntington’s disease (HD) motor neurological...
Wed May 20, 2020 03:00
IJMS, Vol. 21, Pages 3606: The Role of Autophagy for the Regeneration of the Aging Liver International Journal of Molecular Sciences doi: 10.3390/ijms21103606 Authors: Fengming Xu Chuanfeng Hua Hans-Michael Tautenhahn Olaf Dirsch Uta Dahmen Age is one of the key risk factors to develop malignant diseases leading to a high incidence of hepatic tumors in the elderly population. The only curative treatment for hepatic tumors is surgical removal, which initiates liver regeneration....
Wed May 20, 2020 03:00
IJMS, Vol. 21, Pages 3608: Plasma Oxalate as a Predictor of Kidney Function Decline in a Primary Hyperoxaluria Cohort International Journal of Molecular Sciences doi: 10.3390/ijms21103608 Authors: Ronak Jagdeep Shah Lisa E. Vaughan Felicity T. Enders Dawn S. Milliner John C. Lieske This retrospective analysis investigated plasma oxalate (POx) as a potential predictor of end-stage kidney disease (ESKD) among primary hyperoxaluria (PH) patients. PH patients with type 1, 2,...
Wed May 20, 2020 03:00
IJMS, Vol. 21, Pages 3607: Physical Exercise and Myokines: Relationships with Sarcopenia and Cardiovascular Complications International Journal of Molecular Sciences doi: 10.3390/ijms21103607 Authors: Sandra Maria Barbalho Uri Adrian Prync Flato Ricardo José Tofano Ricardo de Alvares Goulart Elen Landgraf Guiguer Cláudia Rucco P. Detregiachi Daniela Vieira Buchaim Adriano Cressoni Araújo Rogério Leone Buchain Fábio Tadeu Rodrigues Reina Piero Biteli Daniela...
Wed May 20, 2020 03:00
IJMS, Vol. 21, Pages 3604: On-Target CRISPR/Cas9 Activity Can Cause Undesigned Large Deletion in Mouse Zygotes International Journal of Molecular Sciences doi: 10.3390/ijms21103604 Authors: Korablev Lukyanchikova Serova Battulin Genome engineering has been tremendously affected by the appearance of the clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (CRISPR/Cas9)-based approach. Initially discovered as an adaptive immune system...
Wed May 20, 2020 03:00
IJMS, Vol. 21, Pages 3603: Clinical and Genetic Overview of Paroxysmal Movement Disorders and Episodic Ataxias International Journal of Molecular Sciences doi: 10.3390/ijms21103603 Authors: Garone Capuano Travaglini Graziola Stregapede Zanni Vigevano Bertini Nicita Paroxysmal movement disorders (PMDs) are rare neurological diseases typically manifesting with intermittent attacks of abnormal involuntary movements. Two main categories of PMDs are recognized...
Wed May 20, 2020 03:00
IJMS, Vol. 21, Pages 3605: Epidermal Growth Factor (EGF) Augments the Invasive Potential of Human Glioblastoma Multiforme Cells via the Activation of Collaborative EGFR/ROS-Dependent Signaling International Journal of Molecular Sciences doi: 10.3390/ijms21103605 Authors: Pudełek Król Catapano Wróbel Czyż Ryszawy Abnormal secretion of epidermal growth factor (EGF) by non-neuronal cells (e.g., glioma-associated microglia) establishes a feedback loop between glioblastoma...
Wed May 20, 2020 03:00
IJMS, Vol. 21, Pages 3600: Zygotic Vsx1 Plays a Key Role in Defining V2a Interneuron Sub-Lineage by Directly Repressing tal1 Transcription in Zebrafish International Journal of Molecular Sciences doi: 10.3390/ijms21103600 Authors: Qi Zhang Haomang Xu Wei Zhao Jianbo Zheng Lei Sun Chen Luo In the spinal cord, excitatory V2a and inhibitory V2b interneurons are produced together by the final division of common P2 progenitors. During V2a and V2b diversification, Tal1 is necessary...
Wed May 20, 2020 03:00
IJMS, Vol. 21, Pages 3602: Synthesis of Fmoc-Triazine Amino Acids and Its Application in the Synthesis of Short Antibacterial Peptidomimetics International Journal of Molecular Sciences doi: 10.3390/ijms21103602 Authors: Gunasekaran Kim Lee Ryu Shin Bang To combat the escalating rise of antibacterial resistance, the development of antimicrobial peptides (AMPs) with a unique mode of action is considered an attractive strategy. However, proteolytic degradation of AMPs...
Wed May 20, 2020 03:00
IJMS, Vol. 21, Pages 3601: MicroRNAs in Intervertebral Disc Degeneration, Apoptosis, Inflammation, and Mechanobiology International Journal of Molecular Sciences doi: 10.3390/ijms21103601 Authors: Cazzanelli Wuertz-Kozak Intervertebral disc (IVD) degeneration is a multifactorial pathological process associated with low back pain, the leading cause of years lived in disability worldwide. Key characteristics of the pathological changes connected with degenerative disc disease (DDD)...
Wed May 20, 2020 03:00
IJMS, Vol. 21, Pages 3599: Understanding the Differentiation, Expansion, Recruitment and Suppressive Activities of Myeloid-Derived Suppressor Cells in Cancers International Journal of Molecular Sciences doi: 10.3390/ijms21103599 Authors: Lim Kim Poh There has been a great interest in myeloid-derived suppressor cells (MDSCs) due to their biological functions in tumor-mediated immune escape by suppressing antitumor immune responses. These cells arise from altered myelopoiesis...
Wed May 20, 2020 03:00
IJMS, Vol. 21, Pages 3598: Role of microRNAs in Hemophilia and Thrombosis in Humans International Journal of Molecular Sciences doi: 10.3390/ijms21103598 Authors: Jankowska Sauna Atreya MicroRNAs (miRNA) play an important role in gene expression at the posttranscriptional level by targeting the untranslated regions of messenger RNA (mRNAs). These small RNAs have been shown to control cellular physiological processes including cell differentiation and proliferation. Dysregulation...
Wed May 20, 2020 03:00
IJMS, Vol. 21, Pages 3597: Placental Microarray Profiling Reveals Common mRNA and lncRNA Expression Patterns in Preeclampsia and Intrauterine Growth Restriction International Journal of Molecular Sciences doi: 10.3390/ijms21103597 Authors: Diana Medina-Bastidas Mario Guzmán-Huerta Hector Borboa-Olivares César Ruiz-Cruz Sandra Parra-Hernández Arturo Flores-Pliego Ivan Salido-Guadarrama Lisbeth Camargo-Marín Eliakym Arambula-Meraz Guadalupe Estrada-Gutierrez Preeclampsia...
Wed May 20, 2020 03:00
JCM, Vol. 9, Pages 1549: Identification of Potential Oral Microbial Biomarkers for the Diagnosis of Periodontitis Journal of Clinical Medicine doi: 10.3390/jcm9051549 Authors: Na Kim Han Kim Lee Lee Chung Periodontitis is a chronic and multifactorial inflammatory disease that can lead to tooth loss. At present, the diagnosis for periodontitis is primarily based on clinical examination and radiographic parameters. Detecting the periodontal pathogens at the subgingival...
Wed May 20, 2020 03:00
JCM, Vol. 9, Pages 1547: An Efficient COVID-19 Prediction Model Validated with the Cases of China, Italy and Spain: Total or Partial Lockdowns? Journal of Clinical Medicine doi: 10.3390/jcm9051547 Authors: Samuel Sanchez-Caballero Miguel A. Selles Miguel A. Peydro Elena Perez-Bernabeu The present work develops an accurate prediction model of the COVID-19 pandemic, capable not only of fitting data with a high regression coefficient but also to predict the overall infections and...
Wed May 20, 2020 03:00
JCM, Vol. 9, Pages 1548: Early Predictors of Clinical Deterioration in a Cohort of 239 Patients Hospitalized for Covid-19 Infection in Lombardy, Italy Journal of Clinical Medicine doi: 10.3390/jcm9051548 Authors: Cecconi Piovani Brunetta Aghemo Greco Ciccarelli Angelini Voza Omodei Vespa Pugliese Parigi Folci Danese Bonovas We described features of hospitalized Covid-19 patients and identified predictors of clinical deterioration....
Wed May 20, 2020 03:00
JCM, Vol. 9, Pages 1545: Specific EEG Encephalopathy Pattern in SARS-CoV-2 Patients Journal of Clinical Medicine doi: 10.3390/jcm9051545 Authors: Pastor Vega-Zelaya Martín Abad We used quantified electroencephalography (qEEG) to define the features of encephalopathy in patients released from the intensive care unit after severe illness from COVID-19. Artifact-free 120–300 s epoch lengths were visually identified and divided into 1 s windows with 10% overlap. Differential...
Wed May 20, 2020 03:00
JCM, Vol. 9, Pages 1546: Agreement between Type 2 Diabetes Risk Scales in a Caucasian Population: A Systematic Review and Report Journal of Clinical Medicine doi: 10.3390/jcm9051546 Authors: Ayensa-Vazquez Leiva Tauler López-González Aguiló Tomás-Salvá Bennasar-Veny Early detection of people with undiagnosed type 2 diabetes (T2D) is an important public health concern. Several predictive equations for T2D have been proposed but most of them have not been externally...
Wed May 20, 2020 03:00
JCM, Vol. 9, Pages 1544: Associations of Sedentary Behaviour, Physical Activity, Cardiorespiratory Fitness and Body Composition with Risk of Sleep-Related Breathing Disorders in Children with Overweight/Obesity: A Cross-Sectional Study Journal of Clinical Medicine doi: 10.3390/jcm9051544 Authors: Lucia V. Torres-Lopez Cristina Cadenas-Sanchez Jairo H. Migueles Mireia Adelantado-Renau Abel Plaza-Florido Patricio Solis-Urra Pablo Molina-Garcia Francisco B. Ortega The...
Wed May 20, 2020 03:00
JCM, Vol. 9, Pages 1543: Increased Cell-Free DNA Plasma Concentration Following Liver Transplantation Is Linked to Portal Hepatitis and Inferior Survival Journal of Clinical Medicine doi: 10.3390/jcm9051543 Authors: Felix Krenzien Shadi Katou Alba Papa Bruno Sinn Christian Benzing Linda Feldbrügge Can Kamali Philipp Brunnbauer Katrin Splith Ralf Roland Lorenz Paul Ritschl Leke Wiering Robert Öllinger Wenzel Schöning Johann Pratschke Moritz Schmelzle...
Wed May 20, 2020 03:00
JCM, Vol. 9, Pages 1540: Comparing Eight Prognostic Scores in Predicting Mortality of Patients with Acute-On-Chronic Liver Failure Who Were Admitted to an ICU: A Single-Center Experience Journal of Clinical Medicine doi: 10.3390/jcm9051540 Authors: Bo-Huan Chen Hsiao-Jung Tseng Wei-Ting Chen Pin-Cheng Chen Yu-Pin Ho Chien-Hao Huang Chun-Yen Lin Limited data is available on long-term outcome predictions for patients with acute-on-chronic liver failure (ACLF) in an intensive...
Wed May 20, 2020 03:00
JCM, Vol. 9, Pages 1541: Liquid Biopsies in Hepatocellular Carcinoma: Are We Winning? Journal of Clinical Medicine doi: 10.3390/jcm9051541 Authors: Tudor Mocan André L. Simão Rui E. Castro Cecília M. P. Rodrigues Artur Słomka Bingduo Wang Christian Strassburg Aliona Wöhler Arnulf G. Willms Miroslaw Kornek Hepatocellular carcinoma (HCC) represents the sixth most common cancer worldwide and the third most common cause of cancer-related death. One of the major...
Wed May 20, 2020 03:00
JCM, Vol. 9, Pages 1542: Outcomes of Chronic Phase Chronic Myeloid Leukemia after Treatment with Multiple Tyrosine Kinase Inhibitors Journal of Clinical Medicine doi: 10.3390/jcm9051542 Authors: Jee Hyun Kong Elliott F. Winton Leonard T. Heffner Manila Gaddh Brittany Hill Jessica Neely Angela Hatcher Meena Joseph Martha Arellano Fuad El-Rassi Audrey Kim Jean Hanna Khoury Vamsi K. Kota We sought to evaluate the outcomes of chronic phase (CP) chronic...
Wed May 20, 2020 03:00
JCM, Vol. 9, Pages 1538: Impact of Midurethral Sling Implantation on Sexual Function in Women with Stress Urinary Incontinence Journal of Clinical Medicine doi: 10.3390/jcm9051538 Authors: Horosz Zwierzchowska Pomian Majkusiak Tomasik Barcz Stress urinary incontinence (SUI) negatively influences sexual functions. However, the available data on sexual activity of patients who underwent midurethral sling (MUS) implantation are inconsistent. Our aim was to evaluate...
Wed May 20, 2020 03:00
JCM, Vol. 9, Pages 1539: Present and Future of Bronchopulmonary Dysplasia Journal of Clinical Medicine doi: 10.3390/jcm9051539 Authors: Bonadies Zaramella Porzionato Perilongo Muraca Baraldi Bronchopulmonary dysplasia (BPD) is the most common respiratory disorder among infants born extremely preterm. The pathogenesis of BPD involves multiple prenatal and postnatal mechanisms affecting the development of a very immature lung. Their combined effects alter the lung’s...
Wed May 20, 2020 03:00
JCM, Vol. 9, Pages 1537: Relationship between Performance on the Mini-Mental State Examination Sub-Items and Activities of Daily Living in Patients with Alzheimer’s Disease Journal of Clinical Medicine doi: 10.3390/jcm9051537 Authors: Gwanghee Han Michio Maruta Yuriko Ikeda Tomohisa Ishikawa Hibiki Tanaka Asuka Koyama Ryuji Fukuhara Shuken Boku Minoru Takebayashi Takayuki Tabira Mini-mental state examination (MMSE) subitems provide useful information about...
Wed May 20, 2020 03:00
JFB, Vol. 11, Pages 33: Anti-Bacterial Properties and Biocompatibility of Novel SiC Coating for Dental Ceramic Journal of Functional Biomaterials doi: 10.3390/jfb11020033 Authors: Samira Esteves Afonso Camargo Azeem S. Mohiuddeen Chaker Fares Jessica L. Partain Patrick H. Carey Fan Ren Shu-Min Hsu Arthur E. Clark Josephine F. Esquivel-Upshaw A 200 nm plasma-enhanced chemical vapor-deposited SiC was used as a coating on dental ceramics to improve anti-bacterial...
Wed May 20, 2020 03:00
JFB, Vol. 11, Pages 32: Determination and Quantification of the Distribution of CN-NL Nanoparticles Encapsulating Glycyrrhetic Acid on Novel Textile Surfaces with Hyperspectral Imaging Journal of Functional Biomaterials doi: 10.3390/jfb11020032 Authors: Kudirat A. Obisesan Simona Neri Elodie Bugnicourt Inmaculada Campos Laura Rodriguez-Turienzo Chitin Lignin nanoparticles (CN-NL), standalone and encapsulating glycyrrhetic acid (GA), were applied on novel substrates for textiles...
Wed May 20, 2020 03:00
JoF, Vol. 6, Pages 68: Fungal Pigments: Potential Coloring Compounds for Wide Ranging Applications in Textile Dyeing Journal of Fungi doi: 10.3390/jof6020068 Authors: Venil Velmurugan Dufossé Devi Ravi Synthetic pigments/non-renewable coloring sources used normally in the textile industry release toxic substances into the environment, causing perilous ecological challenges. To be safer from such challenges of synthetic colorants, academia and industries have explored...
Wed May 20, 2020 03:00
JoF, Vol. 6, Pages 67: High-Frequency Direct Detection of Triazole Resistance in Aspergillus fumigatus from Patients with Chronic Pulmonary Fungal Diseases in India Journal of Fungi doi: 10.3390/jof6020067 Authors: Ashutosh Singh Brijesh Sharma Kaushal Kumar Mahto Jacques F. Meis Anuradha Chowdhary Aspergillosis due to azole-resistant Aspergillus fumigatus is a worldwide problem with major therapeutic implications. In patients with invasive aspergillosis, a low yield of fungal...
Wed May 20, 2020 03:00
J. Imaging, Vol. 6, Pages 36: Comparative Study of Contact Repulsion in Control and Mutant Macrophages Using a Novel Interaction Detection Journal of Imaging doi: 10.3390/jimaging6050036 Authors: José Alonso Solís-Lemus Besaiz J Sánchez-Sánchez Stefania Marcotti Mubarik Burki Brian Stramer Constantino Carlos Reyes-Aldasoro In this paper, a novel method for interaction detection is presented to compare the contact dynamics of macrophages in the Drosophila embryo. The study...
Wed May 20, 2020 03:00
Life, Vol. 10, Pages 73: Higher Responsiveness to Rosuvastatin in Polygenic versus Monogenic Hypercholesterolaemia: A Propensity Score Analysis Life doi: 10.3390/life10050073 Authors: Mickiewicz Futema Ćwiklinska Kuchta Jankowski Kaszubowski Chmara Wasąg Fijałkowski Jaguszewski Humphries Gruchała Background: The monogenic defect in familial hypercholesterolemia (FH) is detected in ∼40% of cases. The majority of mutation-negative patients...
Wed May 20, 2020 03:00
Life, Vol. 10, Pages 72: Ubiquitous Electron Transport in Non-Electron Transfer Proteins Life doi: 10.3390/life10050072 Authors: Stuart Lindsay Many proteins that have no known role in electron transfer processes are excellent electronic conductors. This surprising characteristic is not generally evident in bulk aggregates or crystals, or in isolated, solvated peptides, because the outer hydrophilic shell of the protein presents a barrier to charge injection. Ligands that penetrate this...
Wed May 20, 2020 03:00
Medicina, Vol. 56, Pages 245: Relationship between Vitamin Deficiencies and Co-Occurring Symptoms in Autism Spectrum Disorder Medicina doi: 10.3390/medicina56050245 Authors: Robea Luca Ciobica Recently, connections have been made between feeding and eating problems and autism spectrum disorder (ASD) and between autism pathophysiology and diet issues. These could explain some of the mechanisms which have not yet been discovered or are not sufficiently characterized. Moreover,...
Wed May 20, 2020 03:00
Medicina, Vol. 56, Pages 248: Pleomorphic Adenoma of External Auditory Canal: Case Report of First Endoscopic Resection and Literature Review Medicina doi: 10.3390/medicina56050248 Authors: Sven Beckmann Matthias S. Dettmer Marco D. Caversaccio Roland Giger Lukas Anschuetz Ceruminous pleomorphic adenoma is a very rare, mostly benign tumor originating from the ceruminal glands in the external auditory canal. Histologically, it is a mixed tumor with epithelial and stromal parts...
Wed May 20, 2020 03:00
Medicina, Vol. 56, Pages 249: Are Force Enhancement after Stretch and Muscle Fatigue Due to Effects of Elevated Inorganic Phosphate and Low Calcium on Cross Bridge Kinetics? Medicina doi: 10.3390/medicina56050249 Authors: Degens Jones Background and Objectives: Muscle fatigue is characterised by (1) loss of force, (2) decreased maximal shortening velocity and (3) a greater resistance to stretch that could be due to reduced intracellular Ca2+ and increased Pi, which alter cross bridge...
Wed May 20, 2020 03:00
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