Journal of International Medical Research, Volume 48, Issue 5, May 2020. ObjectiveNOD-like receptor family caspase recruitment domain family domain-containing 5 (NLRC5) is involved in the development of cancer. Our objective was to explore the role of NLRC5 in the progression of endometrial cancer (EC).MethodsThe roles of NLRC5 in migration and invasion of AN3CA EC cells were examined by cell wound-healing assay, Transwell migration, and invasion analysis. Overexpression of NLRC5 was achieved with...
Wed May 20, 2020 13:15
Journal of International Medical Research, Volume 48, Issue 5, May 2020. Acute mediastinitis (AM) is a rare but life-threatening disease. Here, we report a case of AM secondary to endobronchial tuberculosis (EBTB) and pseudomembranous Aspergillus tracheobronchitis (PMATB) co-infection. EBTB was confirmed by tissue culture for Mycobacterium tuberculosis and GeneXpert MTB/RIF (Cepheid, Sunnyvale, CA, USA) detection (simultaneous detection of M. tuberculosis and resistance to rifampin) using endobronchial...
Wed May 20, 2020 13:13
Journal of International Medical Research, Volume 48, Issue 5, May 2020. ObjectiveWe aimed to analyze the risk factors and to establish a predictive tool for the occurrence of bloodstream infections (BSI) in patients with cirrhosis.MethodsA total of 2888 patients with cirrhosis were retrospectively included. Multivariate analysis for risk factors of BSI were tested using logistic regression. Multivariate logistic regression was validated using five-fold cross-validation.ResultsVariables that were...
Wed May 20, 2020 13:09
Journal of International Medical Research, Volume 48, Issue 5, May 2020. ObjectiveTo identify glioma radiomic features associated with proliferation-related Ki-67 antigen and cellular tumour antigen p53 levels, common immunohistochemical markers for differentiating benign from malignant tumours, and to generate radiomic prediction models.MethodsPatients with glioma, who were scanned before therapy using standard brain magnetic resonance imaging (MRI) protocols on T1 and T2 weighted imaging, were...
Wed May 20, 2020 13:06
Journal of International Medical Research, Volume 48, Issue 5, May 2020. ObjectiveThis study was performed to compare the modified direct closure method and traditional skin grafting for wounds at the anterolateral thigh (ALT) flap donor site.MethodsAmong 29 consecutive patients with wounds at the ALT flap donor site, 14 underwent the modified direct closure method (MDC group) and 15 underwent traditional skin grafting (SG group). The operative time, follow-up time, complications, Vancouver Scar...
Wed May 20, 2020 10:52
Journal of International Medical Research, Volume 48, Issue 5, May 2020. ObjectiveTo analyse the incidence and baseline predictors of the left ventricular ejection fraction (LVEF) returning to normal after dilated cardiomyopathy (DCM) following intervention with standard anti-heart failure (HF) medication in postmenopausal women.MethodsData from consecutive postmenopausal women who were first diagnosed with DCM and received anti-HF treatment during 2011 to 2018 were prospectively retrieved. The study...
Wed May 20, 2020 10:36
Journal of International Medical Research, Volume 48, Issue 5, May 2020.
Wed May 20, 2020 10:30
Journal of International Medical Research, Volume 48, Issue 5, May 2020. The entry of a metallic foreign body into the thyroid gland via the esophagus is a rare occurrence, with no previously reported cases. We present a 42-year-old woman who was admitted to hospital with right-sided neck pain, reporting that she had inadvertently swallowed a fish bone. She underwent laryngoscopy, which showed no fish bone in the throat, and no obvious bleeding in the bilateral tonsils and pear-shaped fossa. X-ray...
Tue May 19, 2020 13:57
Journal of International Medical Research, Volume 48, Issue 5, May 2020. Ligamentum arteriosum calcification is the calcification or ossification of arterial ligaments. However, on computed tomography images, ligamentum arteriosum calcification is often mistaken for esophageal perforation when a patient has a medical history of foreign body ingestion. Ligamentum arteriosum calcification is uncommon in clinical practice. In this case report, we confirm the presence of this condition intraoperatively,...
Tue May 19, 2020 13:53
Journal of International Medical Research, Volume 48, Issue 5, May 2020. ObjectiveTo investigate the clinical features and evaluate the prognostic factors in patients with bone metastases from non-small cell lung cancer (NSCLC).MethodsWe retrospectively investigated 356 patients with NSCLC with bone metastases from January 2012 to December 2017. The overall survival (OS) and 1-year survival rate were calculated by Kaplan–Meier analysis and compared by univariate analysis using the log-rank test....
Tue May 19, 2020 13:48
Journal of International Medical Research, Volume 48, Issue 5, May 2020. ObjectiveThis study was performed to investigate the influence of a standard Oxford vertical cut on the coronal coverage and rotation of the tibial component and determine whether a relationship exists between coverage and rotation.MethodsWe retrospectively analyzed 71 patients with anteromedial osteoarthritis of the knee treated by Oxford unicompartmental knee arthroplasty in one center from October 2016 to October 2017. The...
Tue May 19, 2020 13:42
Journal of Neurotrauma, Ahead of Print.
Wed May 20, 2020 10:00
Tissue Engineering Part A, Ahead of Print.
Wed May 20, 2020 10:00
Abstact Objective to compare the smallest thickness that can be perceived between occluding teeth (occlusal tactile acuity, OTA) of Temporomandibular Disorder pain (TMD‐P) patients with that of control (CTR) individuals. Methods Twenty TMD‐P patients (17 women, 3 men, mean age: 31.3±10.4 years) diagnosed according to the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) protocol and 20 age‐ and gender‐matched controls (17 women, 3 men, mean age: 31.4±10.5 years) were enrolled....
Wed May 20, 2020 11:09
The cover image is based on the Original Article The relationship between sarcopenia and oral sarcopenia in elderly people by Ryuichiro Kobuchi et al., https://doi.org/10.1111/joor.12948.
Fri May 15, 2020 21:36
Fri May 15, 2020 21:36
Tue May 19, 2020 16:53
Abstract Background Most clinical studies in dentistry are conducted in university‐based settings. However, whether findings can be generalized to private dental practices is not clear. Aims of this study were to determine patients’ criteria for choosing a dentist, and to assess whether criteria differ between patients in university dental clinic and private dental practices. Material and Methods In this cross‐sectional study, a convenience sample of 300 subjects involving dental patients...
Tue May 19, 2020 12:29
ABSTRACT Background In 2016, the Japanese Society of Gerodontology (JSG) proposed the concept of “oral hypofunction (OHF),” and recommended two initial criteria for reduced occlusal force (ROF): <200 N of maximum occlusal force (MOF) and <20 remaining teeth. However, the JSG stated that these criteria need to be reviewed by accumulating further evidence. Objective To examine the validity and equivalence of the two criteria for ROF in the diagnostic criteria for OHF by using the incidence...
Tue May 19, 2020 12:00
JPRAS is a global journal, and that world changed on 9th January 2020 when the causative agent for a cluster of pneumonia cases of unknown origin in Wuhan, Hubei Province, China was characterised as novel coronavirus disease 2019 (COVID-19). Recent weeks have seen COVID-19 finally transform from a devastating regional epidemic into a true global pandemic. While 80% of cases are self-limiting, 14% merit inpatient care and ∼6% require intensive care.1 At the time of writing, 3,664,143 individuals had...
Fri May 01, 2020 03:00
As COVID-19 spreads quickly from Asia via Europe to the rest of the world, hospitals are evolving into hot zones for treatment and transmission of this disease. With the increasing acceptance that operating theatres are high risk areas for transmission of respiratory infections for both patients and surgeons,1 and with our health care systems being generally well-designed to only deal with occasional high-risk cases, there is an obvious need to evolve our practice. Although social media campaigns...
Wed May 20, 2020 03:00
S2k guidelines for the treatment of pemphigus vulgaris/foliaceus and bullous pemphigoid: 2019 update
Fri May 15, 2020 11:54
Zusammenfassung Hintergrund Psoriasis ist eine chronische, schubförmig verlaufende Erkrankung, die häufig mit Komorbiditäten einhergeht. Während die Wechselwirkungen mit kardiovaskulären und metabolischen Einflussfaktoren bereits untersucht wurden, ist über den Zusammenhang mit einer Beeinträchtigung der Nierenfunktion wenig bekannt. Materialien und Methodik Wir führten eine Kohortenstudie mit 219 Psoriasis‐Patienten durch, in der wir die chronische Nierenerkrankung (CKD), die eGFR und...
Fri May 15, 2020 11:54
Fri May 15, 2020 11:54
Streben nach Symmetrie bei der Rekonstruktion des apikalen Oberlippendreiecks mit einem Hatchet flap
Fri May 15, 2020 11:54
Fri May 15, 2020 11:54
Zusammenfassung Hintergrund und Ziele Die histopathologische Diagnose eines Fluoroskopie‐induzierten Röntgenulkus (RU) kann eine Herausforderung darstellen, insbesondere wenn keine Informationen über eine vorausgegangene Strahlenexposition vorliegen. Die wichtigste Differenzialdiagnose ist die zirkumskripte Sklerodermie (ZS). Ziel dieser Studie war die Identifikation klinischer und histopathologischer Merkmale, mit deren Hilfe sich RU und ZS unterscheiden lassen. Patienten und Methodik Wir...
Fri May 15, 2020 11:54
Fri May 15, 2020 11:54
Fri May 15, 2020 11:54
Zusammenfassung Bisher sind nur wenige Ergebnisse einer Re‐Induktion (Rechallenge) von Checkpoint‐Inhibitor‐Therapien publiziert. Wir präsentieren die erste Übersicht aller dazu international, englischsprachig veröffentlichten Arbeiten. 570 Patienten konnten in die Analyse eingeschlossen werden. Für die Auswertung wurde in vier Gruppen unterteilt: 1) Rechallenge mit Anti‐PD1 nach Progress unter Anti‐PD1‐Therapie 2) Rechallenge mit Anti‐PD1 und CTLA4 nach Progress unter Anti‐PD1‐Therapie, 3) Rechallenge...
Fri May 15, 2020 11:54
Summary Background and objectives Histopathologic diagnosis of fluoroscopy‐induced radiation ulcer (FIRU) can be challenging if the past history of radiation exposure is unknown. Morphea is the most important differential diagnosis. This study was intended to identify clinical and pathologic features that can be used to distinguish FIRU from morphea. Patients and methods We performed a retrospective study on 25 specimens from 15 patients with FIRU and 21 specimens from 21 patients with...
Fri May 15, 2020 11:54
Fri May 15, 2020 11:54
Summary Various techniques have been described for the reconstruction of surgical defects of the upper lip after skin cancer. Here, we propose a technique for reconstructing medium or large defects located at the junction of the nasogenian and nasolabial folds with a hatchet flap. We report on three patients treated with this technique, describing the surgical procedure and some interesting caveats. Two patients reconstructed with direct closure in this location are described in order to emphasize...
Fri May 15, 2020 11:54
Fri May 15, 2020 11:54
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