Pharmaceutics, Vol. 12, Pages 441: MERS-CoV Spike Protein Vaccine and Inactivated Influenza Vaccine Formulated with Single Strand RNA Adjuvant Induce T-Cell Activation through Intranasal Immunization in Mice Pharmaceutics doi: 10.3390/pharmaceutics12050441 Authors: Kim Kwak Kang Bang Lee Park Kim Park Hwang Lee Nam The effectiveness of vaccines is enhanced by adding adjuvants. Furthermore, the selection of an inoculation route depends on the type...
Sun May 10, 2020 03:00
Pharmaceutics, Vol. 12, Pages 440: Vascular Drug Delivery Using Carrier Red Blood Cells: Focus on RBC Surface Loading and Pharmacokinetics Pharmaceutics doi: 10.3390/pharmaceutics12050440 Authors: Patrick M. Glassman Carlos H. Villa Anvay Ukidve Zongmin Zhao Paige Smith Samir Mitragotri Alan J. Russell Jacob S. Brenner Vladimir R. Muzykantov Red blood cells (RBC) have great potential as drug delivery systems, capable of producing unprecedented changes in pharmacokinetics,...
Sat May 09, 2020 03:00
Pharmaceutics, Vol. 12, Pages 439: PLGA Nanoparticles for the Intraperitoneal Administration of CBD in the Treatment of Ovarian Cancer: In Vitro and In Ovo Assessment Pharmaceutics doi: 10.3390/pharmaceutics12050439 Authors: Ana I. Fraguas-Sánchez Ana I. Torres-Suárez Marie Cohen Florence Delie Daniel Bastida-Ruiz Lucile Yart Cristina Martin-Sabroso Ana Fernández-Carballido The intraperitoneal administration of chemotherapeutics has emerged as a potential route in...
Sat May 09, 2020 03:00
Pharmaceutics, Vol. 12, Pages 438: Compression-Induced Phase Transitions of Bicalutamide Pharmaceutics doi: 10.3390/pharmaceutics12050438 Authors: Joanna Szafraniec-Szczęsny Agata Antosik-Rogóż Justyna Knapik-Kowalczuk Mateusz Kurek Ewa Szefer Karolina Gawlak Krzysztof Chmiel Sebastian Peralta Krzysztof Niwiński Krzysztof Pielichowski Marian Paluch Renata Jachowicz The formation of solid dispersions with the amorphous drug dispersed in the polymeric matrix...
Sat May 09, 2020 03:00
Pharmaceutics, Vol. 12, Pages 436: Erratum: Mangas-Sanjuán, V.; et al. Assessment of the Inter-Batch Variability of Microstructure Parameters in Topical Semisolids and Impact on the Demonstration of Equivalence. Pharmaceutics 2019, 11, 503 Pharmaceutics doi: 10.3390/pharmaceutics12050436 Authors: Víctor Mangas-Sanjuán María Pleguezuelos-Villa Matilde Merino-Sanjuán Mᵃ Jesús Hernández Amparo Nácher Alfredo García-Arieta Daniel Peris Irene Hidalgo Lluís Soler Marta...
Sat May 09, 2020 03:00
Pharmaceutics, Vol. 12, Pages 437: Enhanced Oral Bioavailability of the Pharmacologically Active Lignin Magnolol via Zr-Based Metal Organic Framework Impregnation Pharmaceutics doi: 10.3390/pharmaceutics12050437 Authors: Joshua H. Santos Mark Tristan J. Quimque Allan Patrick G. Macabeo Mary Jho-Anne T. Corpuz Yun-Ming Wang Tsai-Te Lu Chia-Her Lin Oliver B. Villaflores Bioavailability plays an important role in drug activity in the human body, as certain drug amounts...
Sat May 09, 2020 03:00
Pharmaceutics, Vol. 12, Pages 434: Lactoferrin Contributes a Renoprotective Effect in Acute Kidney Injury and Early Renal Fibrosis Pharmaceutics doi: 10.3390/pharmaceutics12050434 Authors: Yung-Ho Hsu I-Jen Chiu Yuh-Feng Lin Yi-Jie Chen Yu-Hsuan Lee Hui-Wen Chiu Patients with acute kidney injury (AKI) who survive the acute stage are at notable risk for chronic kidney disease (CKD) progression. There is no single therapy that can effectively prevent the AKI to CKD transition....
Fri May 08, 2020 03:00
Pharmaceutics, Vol. 12, Pages 435: Erythrocytes as Carriers of Therapeutic Enzymes Pharmaceutics doi: 10.3390/pharmaceutics12050435 Authors: Bridget E. Bax Therapeutic enzymes are administered for the treatment of a wide variety of diseases. They exert their effects through binding with a high affinity and specificity to disease-causing substrates to catalyze their conversion to a non-noxious product, to induce an advantageous physiological change. However, the metabolic and clinical...
Fri May 08, 2020 03:00
Pharmaceutics, Vol. 12, Pages 433: Physicochemical Properties of Poly-Vinyl Polymers and Their Influence on Ketoprofen Amorphous Solid Dispersion Performance: A Polymer Selection Case Study Pharmaceutics doi: 10.3390/pharmaceutics12050433 Authors: Emer Browne Zelalem A. Worku Anne Marie Healy When developing an amorphous solid dispersion (ASD), a prudent choice of polymer is critical to several aspects of ASD performance including: processability, solid state stability and dissolution...
Fri May 08, 2020 03:00
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