Antibiotics, Vol. 9, Pages 243: Identification and Rational Design of a Novel Antibacterial Peptide Dermaseptin-AC from the Skin Secretion of the Red-Eyed Tree Frog Agalychnis callidryas Antibiotics doi: 10.3390/antibiotics9050243 Authors: Gong Pei Ren Chen Wang Ma Xi Chen Shaw Zhou Antibiotic resistance represents a tremendous contemporary clinical challenge. Given this challenge, antimicrobial peptides (AMPs) are regarded as one of the most promising...
Sun May 10, 2020 03:00
Antibiotics, Vol. 9, Pages 242: Encapsulation of the Antistaphylococcal Endolysin LysRODI in pH-Sensitive Liposomes Antibiotics doi: 10.3390/antibiotics9050242 Authors: Silvia Portilla Lucía Fernández Diana Gutiérrez Ana Rodríguez Pilar García Phage lysins are promising new therapeutics against multidrug-resistant bacteria. These so-called enzybiotics offer, amongst their most notable advantages, high target specificity and low resistance development. Moreover, there are...
Sat May 09, 2020 03:00
Antibiotics, Vol. 9, Pages 241: Salvage Bacteriophage Therapy for a Chronic MRSA Prosthetic Joint Infection Antibiotics doi: 10.3390/antibiotics9050241 Authors: James B. Doub Vincent Y. Ng Aaron J. Johnson Magdalena Slomka Joseph Fackler Bri’Anna Horne Michael J. Brownstein Matthew Henry Francisco Malagon Biswajit Biswas This is a case of a 72 year old male with a chronic methicillin-resistant Staphylococcus aureus prosthetic joint infection. After the third...
Sat May 09, 2020 03:00
Antibiotics, Vol. 9, Pages 239: Counting Replication Origins to Measure Growth of Pathogens Antibiotics doi: 10.3390/antibiotics9050239 Authors: Charbon Haugan Frimodt-Møller Løbner-Olesen For the past several decades, the success of bacterial strains in infecting their host has been essentially ascribed to the presence of canonical virulence genes. While it is unclear how much growth rate impacts the outcome of an infection, it is long known that the efficacy of the most...
Fri May 08, 2020 03:00
Antibiotics, Vol. 9, Pages 240: PYED-1 Inhibits Biofilm Formation and Disrupts the Preformed Biofilm of Staphylococcus aureus Antibiotics doi: 10.3390/antibiotics9050240 Authors: Vollaro Esposito Esposito Zarrilli Guaragna Gregorio Pregnadiene-11-hydroxy-16α,17α-epoxy-3,20-dione-1 (PYED-1), a heterocyclic corticosteroid derivative of deflazacort, exhibits broad-spectrum antibacterial activity against Gram-negative and Gram-positive bacteria. Here,...
Fri May 08, 2020 03:00
Antibiotics, Vol. 9, Pages 237: High Abundance of Proteobacteria in Ileo-Anal Pouch Anastomosis and Increased Abundance of Fusobacteria Associated with Increased Pouch Inflammation Antibiotics doi: 10.3390/antibiotics9050237 Authors: Andreas Munk Petersen Hengameh Chloé Mirsepasi-Lauridsen Marianne K. Vester-Andersen Nikolaj Sørensen Karen Angeliki Krogfelt Flemming Bendtsen Low diversity intestinal dysbiosis has been associated with inflammatory bowel disease, including...
Fri May 08, 2020 03:00
Antibiotics, Vol. 9, Pages 238: Toxic Effect of Vancomycin on Viability and Functionality of Different Cells Involved in Tissue Regeneration Antibiotics doi: 10.3390/antibiotics9050238 Authors: Joy Braun Stefanie Eckes Pol Maria Rommens Katja Schmitz Daniela Nickel Ulrike Ritz To prevent infections local delivery of antibiotics is a useful tool. Especially in bone fractures, vancomycin impregnated bone cements are often used allowing high concentrations of antibiotics...
Fri May 08, 2020 03:00
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