Cancers, Vol. 12, Pages 1202: Regulation of Tumor Immunity by Lysophosphatidic Acid Cancers doi: 10.3390/cancers12051202 Authors: Sue Chin Lee Mélanie A. Dacheux Derek D. Norman Louisa Balázs Raul M. Torres Corinne E. Augelli-Szafran Gábor J. Tigyi The tumor microenvironment (TME) may be best conceptualized as an ecosystem comprised of cancer cells interacting with a multitude of stromal components such as the extracellular matrix (ECM), blood and lymphatic networks,...
Cancers, Vol. 12, Pages 1201: mTOR Pathway Expression as Potential Predictive Biomarker in Patients with Advanced Neuroendocrine Tumors Treated with Everolimus Cancers doi: 10.3390/cancers12051201 Authors: Fabio Gelsomino Andrea Casadei-Gardini Francesco Caputo Giulio Rossi Federica Bertolini Tiziana Petrachi Andrea Spallanzani Elisa Pettorelli Shaniko Kaleci Gabriele Luppi Background. Everolimus (Eve), which is a mammalian target of Rapamicin (mTOR) inhibitor,...
Cancers, Vol. 12, Pages 1200: Long Non-Coding RNA PANTR1 is Associated with Poor Prognosis and Influences Angiogenesis and Apoptosis in Clear-Cell Renal Cell Cancer Cancers doi: 10.3390/cancers12051200 Authors: Maximilian Seles Georg C. Hutterer Johannes Foßelteder Marek Svoboda Margit Resel Dominik A. Barth Renate Pichler Thomas Bauernhofer Richard E. Zigeuner Karl Pummer Ondrej Slaby Christiane Klec Martin Pichler POU3F3 adjacent non-coding transcript...
Cancers, Vol. 12, Pages 1199: Clinical Theragnostic Potential of Diverse miRNA Expressions in Prostate Cancer: A Systematic Review and Meta-Analysis Cancers doi: 10.3390/cancers12051199 Authors: Rama Jayaraj Greg Raymond Sunil Krishnan Katherine S. Tzou Siddhartha Baxi M. Ravishankar Ram Suresh Kumar Govind Harish C. Chandramoorthy Faisal N. Abu-Khzam Peter Shaw Background: Prostate cancer (PrC) is the second-most frequent cancer in men, its incidence is emerging...
Cancers, Vol. 12, Pages 1198: Nanoemulsions as Delivery Systems for Poly-Chemotherapy Aiming at Melanoma Treatment Cancers doi: 10.3390/cancers12051198 Authors: Chiara Dianzani Chiara Monge Gianluca Miglio Loredana Serpe Katia Martina Luigi Cangemi Chiara Ferraris Silvia Mioletti Sara Osella Casimiro Luca Gigliotti Elena Boggio Nausicaa Clemente Umberto Dianzani Luigi Battaglia Aims: Advanced melanoma is characterized by poor outcome. Despite the...
Cancers, Vol. 12, Pages 1197: Long Non-Coding RNA HOTAIR in Breast Cancer Therapy Cancers doi: 10.3390/cancers12051197 Authors: Monica Cantile Maurizio Di Bonito Margherita Cerrone Francesca Collina Michelino De Laurentiis Gerardo Botti Breast cancer (BC) is the most common cancer type among women, and morbidity and mortality rates are still very high. Despite new innovative therapeutic approaches for all BC molecular subtypes, the discovery of new molecular biomarkers...
Cancers, Vol. 12, Pages 1192: The Role of HPV and Non-HPV Sexually Transmitted Infections in Patients with Oropharyngeal Carcinoma: A Case Control Study Cancers doi: 10.3390/cancers12051192 Authors: Barbara Kofler Johannes Laimer Emanuel Bruckmoser Teresa B. Steinbichler Annette Runge Volker H. Schartinger Dorothee von Laer Wegene Borena Background: Certain high-risk (hr) types of human papillomavirus (HPV) can cause cervical cancer in women and penile cancer in...
Cancers, Vol. 12, Pages 1195: Real-Time Visualization of the Mascagni-Sappey Pathway Utilizing ICG Lymphography Cancers doi: 10.3390/cancers12051195 Authors: Anna Rose Johnson Melisa D. Granoff Hiroo Suami Bernard T. Lee Dhruv Singhal Background: Anatomic variations in lymphatic drainage pathways of the upper arm may have an important role in the pathophysiology of lymphedema development. The Mascagni–Sappey (M–S) pathway, initially described in 1787 by...
Cancers, Vol. 12, Pages 1196: Oncogene-Addicted Non-Small-Cell Lung Cancer: Treatment Opportunities and Future Perspectives Cancers doi: 10.3390/cancers12051196 Authors: Miriam Grazia Ferrara Vincenzo Di Noia Ettore D’Argento Emanuele Vita Paola Damiano Antonella Cannella Marta Ribelli Sara Pilotto Michele Milella Giampaolo Tortora Emilio Bria Before the introduction of tyrosine kinase inhibitors (TKIs) for a particular subgroup of patients, despite platinum-based...
Cancers, Vol. 12, Pages 1193: Chromenopyrimidinone Controls Stemness and Malignancy by suppressing CD133 Expression in Hepatocellular Carcinoma Cancers doi: 10.3390/cancers12051193 Authors: Yeonhwa Song Sanghwa Kim Hyeryon Lee Joo Hwan No Hyung Chul Ryu Jason Kim Jee Woong Lim Moonhee Kim Inhee Choi Haeng Ran Seo Hepatocellular carcinoma (HCC) is a highly malignant human cancer that has increasing mortality rates worldwide. Because CD133+ cells control tumor...
Cancers, Vol. 12, Pages 1194: Relationships and Qualitative Evaluation Between Diffusion-Weighted Imaging and Pathologic Findings of Resected Lung Cancers Cancers doi: 10.3390/cancers12051194 Authors: Katsuo Usuda Shun Iwai Aika Yamagata Atsushi Sekimura Nozomu Motono Munetaka Matoba Mariko Doai Sohsuke Yamada Yoshimichi Ueda Keiya Hirata Hidetaka Uramoto For detecting malignant tumors, diffusion-weighted magnetic resonance imaging (DWI) as well as fluoro-2-deoxy-glucose...
Cancers, Vol. 12, Pages 1190: Added Value of Computed Tomography to Ultrasonography for Assessing LN Metastasis in Preoperative Patients with Thyroid Cancer: Node-By-Node Correlation Cancers doi: 10.3390/cancers12051190 Authors: Roh-Eul Yoo Ji-hoon Kim Inpyeong Hwang Koung Mi Kang Tae Jin Yun Seung Hong Choi Chul-Ho Sohn Sun-Won Park Diagnostic accuracy of US in the evaluation of lymph node (LN) metastasis for thyroid cancer patients is limited. We investigated the...
Cancers, Vol. 12, Pages 1191: The Role of Hyperglycemia in Endometrial Cancer Pathogenesis Cancers doi: 10.3390/cancers12051191 Authors: Byrne Martin Kosasih Caruana Farrell Endometrial cancer is one of the most common cancers in women worldwide and its incidence is increasing. Epidemiological evidence shows a strong association between endometrial cancer and obesity, and multiple mechanisms linking obesity and cancer progression have been described. However, it remains...
Cancers, Vol. 12, Pages 1188: PIM-1 Is Overexpressed at a High Frequency in Circulating Tumor Cells from Metastatic Castration-Resistant Prostate Cancer Patients Cancers doi: 10.3390/cancers12051188 Authors: Markou Tzanikou Strati Zavridou Mastoraki Bournakis Lianidou PIM-1 is an oncogene involved in cell cycle progression, cell growth, cell survival and therapy resistance, activated in many types of cancer, and is now considered as a very promising target for...
Cancers, Vol. 12, Pages 1187: The Relationship between ECOG-PS, mGPS, BMI/WL Grade and Body Composition and Physical Function in Patients with Advanced Cancer Cancers doi: 10.3390/cancers12051187 Authors: Dolan Daly Simmons Ryan Sim Fallon Power Wilcock Maddocks Bennett Usborne Laird McMillan Cancer remains one of the leading causes of mortality worldwide and the associated reduction in physical function has a marked impact on both quality...
Cancers, Vol. 12, Pages 1189: Targeted Dual Intervention-Oriented Drug-Encapsulated (DIODE) Nanoformulations for Improved Treatment of Pancreatic Cancer Cancers doi: 10.3390/cancers12051189 Authors: Madamsetty Pal Dutta Wang Mukhopadhyay Despite recent advancements, effective treatment for pancreatic ductal adenocarcinoma (PDAC) has remained elusive. The overall survival rate in PDAC patients has been dismally low due to resistance to standard therapies. In fact, the...
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