Biomolecules, Vol. 10, Pages 742: Blueberry-Derived Exosome-Like Nanoparticles Counters the Response to TNF-α-Induced Change on Gene Expression in EA.hy926 Cells

Biomolecules, Vol. 10, Pages 742: Blueberry-Derived Exosome-Like Nanoparticles Counters the Response to TNF-α-Induced Change on Gene Expression in EA.hy926 Cells Biomolecules doi: 10.3390/biom10050742 Authors: Mariangela De Robertis Angelo Sarra Valentina D’Oria Francesco Mura Federico Bordi Paolo Postorino Deborah Fratantonio Exosome-like nanoparticles (ELNs) are attracting interest as important vehicles of intercellular communication, both in prokaryotes and eukaryotes....

Biomolecules

Sun May 10, 2020 03:00

Biomolecules, Vol. 10, Pages 741: Sorbaria kirilowii Ethanol Extract Exerts Anti-Inflammatory Effects In Vitro and In Vivo by Targeting Src/Nuclear Factor (NF)-κB

Biomolecules, Vol. 10, Pages 741: Sorbaria kirilowii Ethanol Extract Exerts Anti-Inflammatory Effects In Vitro and In Vivo by Targeting Src/Nuclear Factor (NF)-κB Biomolecules doi: 10.3390/biom10050741 Authors: Jiwon Jang Jong Sub Lee Young-Jin Jang Eui Su Choung Wan Yi Li Sang Woo Lee Eunji Kim Jong-Hoon Kim Jae Youl Cho Inflammation is a fundamental process for defending against foreign antigens that involves various transcriptional regulatory processes as well...

Biomolecules

Sun May 10, 2020 03:00

Biomolecules, Vol. 10, Pages 740: Ticagrelor Prevents Endothelial Cell Apoptosis through the Adenosine Signalling Pathway in the Early Stages of Hypoxia

Biomolecules, Vol. 10, Pages 740: Ticagrelor Prevents Endothelial Cell Apoptosis through the Adenosine Signalling Pathway in the Early Stages of Hypoxia Biomolecules doi: 10.3390/biom10050740 Authors: Catherine Feliu Hélène Peyret Sylvie Brassart-Pasco Floriane Oszust Gaël Poitevin Philippe Nguyen Hervé Millart Zoubir Djerada Background: Several studies have reported the beneficial effects of anti-platelet drugs in cardioprotection against ischaemia–reperfusion...

Biomolecules

Sat May 09, 2020 03:00

Biomolecules, Vol. 10, Pages 739: Identification and Evolution of the WUSCHEL-Related Homeobox Protein Family in Bambusoideae

Biomolecules, Vol. 10, Pages 739: Identification and Evolution of the WUSCHEL-Related Homeobox Protein Family in Bambusoideae Biomolecules doi: 10.3390/biom10050739 Authors: Xiangyu Li Juan Li Miaomiao Cai Huifang Zheng Zhanchao Cheng Jian Gao Bamboos (Bambusoideae) are fast-growing species due to their rapid growth rate and ability to reproduce annually via cloned buds produced on the rhizome. WUSCHEL-related homeobox (WOX) genes have been reported to regulate shoot apical...

Biomolecules

Sat May 09, 2020 03:00

Biomolecules, Vol. 10, Pages 738: Chemoenzymatic Synthesis and Biological Evaluation for Bioactive Molecules Derived from Bacterial Benzoyl Coenzyme A Ligase and Plant Type III Polyketide Synthase

Biomolecules, Vol. 10, Pages 738: Chemoenzymatic Synthesis and Biological Evaluation for Bioactive Molecules Derived from Bacterial Benzoyl Coenzyme A Ligase and Plant Type III Polyketide Synthase Biomolecules doi: 10.3390/biom10050738 Authors: Kamal Adhikari I-Wen Lo Chun-Liang Chen Yung-Lin Wang Kuan-Hung Lin Saeid Malek Zadeh Rajesh Rattinam Yi-Shan Li Chang-Jer Wu Tsung-Lin Li Plant type III polyketide synthases produce diverse bioactive molecules with...

Biomolecules

Sat May 09, 2020 03:00

Biomolecules, Vol. 10, Pages 737: Histidyl-Proline Diketopiperazine Isomers as Multipotent Anti-Alzheimer Drug Candidates

Biomolecules, Vol. 10, Pages 737: Histidyl-Proline Diketopiperazine Isomers as Multipotent Anti-Alzheimer Drug Candidates Biomolecules doi: 10.3390/biom10050737 Authors: Hasan Turkez Ivana Cacciatore Mehmet Enes Arslan Erika Fornasari Lisa Marinelli Antonio Di Stefano Adil Mardinoglu Cyclic dipeptides administered by both parenteral and oral routes are suggested as promising candidates for the treatment of neurodegeneration-related pathologies. In this study, we tested...

Biomolecules

Sat May 09, 2020 03:00

Biomolecules, Vol. 10, Pages 736: D-Loop Mutation G42A/G46A Decreases Actin Dynamics

Biomolecules, Vol. 10, Pages 736: D-Loop Mutation G42A/G46A Decreases Actin Dynamics Biomolecules doi: 10.3390/biom10050736 Authors: Matsuzaki Fujiwara Kashima Matsumoto Oda Hayashi Maeda Takiguchi Maéda Narita Depolymerization and polymerization of the actin filament are indispensable in eukaryotes. The DNase I binding loop (D-loop), which forms part of the interface between the subunits in the actin filament, is an intrinsically disordered loop...

Biomolecules

Fri May 08, 2020 03:00

Biomolecules, Vol. 10, Pages 735: Nanotechnology-Based Strategies to Develop New Anticancer Therapies

Biomolecules, Vol. 10, Pages 735: Nanotechnology-Based Strategies to Develop New Anticancer Therapies Biomolecules doi: 10.3390/biom10050735 Authors: Magro Venerando Macone Canettieri Agostinelli Vianello The blooming of nanotechnology has made available a limitless landscape of solutions responding to crucial issues in many fields and, nowadays, a wide choice of nanotechnology-based strategies can be adopted to circumvent the limitations of conventional therapies...

Biomolecules

Fri May 08, 2020 03:00

Biomolecules, Vol. 10, Pages 734: Challenges and Advances in Genome Editing Technologies in Streptomyces

Biomolecules, Vol. 10, Pages 734: Challenges and Advances in Genome Editing Technologies in Streptomyces Biomolecules doi: 10.3390/biom10050734 Authors: Yawei Zhao Guoquan Li Yunliang Chen Yinhua Lu The genome of Streptomyces encodes a high number of natural product (NP) biosynthetic gene clusters (BGCs). Most of these BGCs are not expressed or are poorly expressed (commonly called silent BGCs) under traditional laboratory experimental conditions. These NP BGCs represent an...

Biomolecules

Fri May 08, 2020 03:00