Chronic granulomatous disease (CGD) is a rare primary immunodeficiency disorder caused by a defect in the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase complex. The disease primarily presents wit...
The National Review of Asthma Deaths UK highlighted that 46% of deaths could be avoided and recommended that all sufferers receive a structured asthma annual review which assess asthma control. In primary care...
This study was performed to determine whether there was any association between abnormal DNA methylation of a thymic stromal lymphopoietin (TSLP) locus and pathogenesis of chronic rhinosinusitis (CRS).
In this paper, we review methodological approaches used in studies that evaluated the association between occupational exposure to quaternary ammonium compounds (quats) and occupational asthma. This associatio...
Blood has proven to be a useful resource for molecular analysis in numerous biomedical studies, with peripheral blood mononuclear cells (PBMCs) and whole blood being the major specimen types. However, comparat...
Background This study was intended to review our management strategy for sinonasal squamous cell carcinomas (SNSCCs) with orbital invasion and to explore the role of radiotherapy in orbital preservation. Methods We retrospectively analyzed 93 SNSCC patients with orbital invasion who underwent radiotherapy with or without surgery over the past 15 years. The degree of orbital invasion was classified into 3 grades. Results Eighty‐eight patients presented with T4 tumors and 36 had grade...
Background Sinonasal mucosal melanoma (SMM) is a rare, aggressive cancer, optimally managed with complete surgical resection. This study aimed to assess the impact of surgical approach on outcomes by comparison of cases managed with open vs endoscopic resection. Methods The National Cancer Database 2010–2015 datasets were queried for all cases of non‐metastatic SMM initially managed with definitive surgery. Patients were grouped according to surgical approach (open vs endoscopic) and compared...
This review provides an overview of the literature on hypersensitivity reactions during procedures to commonly used contrast agents and dyes. A synthesis of current knowledge on clinical symptoms, epidemiology and risk factors, pathomechanism and management of hypersensitivity reactions to these substances is presented.
Pediatric asthma affects 8 million U.S. children and approximately 50% experience an acute asthma exacerbation each year.1,2 Despite national guidelines recommending daily anti-inflammatory or controller medication to treat persistent and uncontrolled asthma,3 most inner-city children with persistent asthma do not receive guideline-based therapy.4 Understanding factors associated with underuse of controller medication may inform clinical interventions to improve asthma control in these high risk...
Allergic diseases such as atopic dermatitis (AD), food allergy (FA), asthma and allergic rhinitis (AR) are common; according to a national birth cohort study in Japan, almost half of pregnant women reported a history of allergic disease.1 Given that genetic factors, including family history, are predictors of allergic diseases in offspring, we expect the birth of many infants who carry a high risk of developing allergies. Among allergy prevention strategies, the effectiveness of primary prevention...
Previous studies have suggested that exposures to indoor air-polluting factors during pregnancy and early life can influence childhood allergy development. These exposures have been investigated in singularity, however the effect of simultaneous exposure to multiple factors remains unclear.
Anaphylaxis is commonly encountered in the allergy clinic especially in practices with a large number of patients on immunotherapy (IT). Risk factors which may increase the frequency or severity of anaphylaxis are still being investigated. To our knowledge, a study has not been conducted which evaluated the relationship between being on any antihypertensive and the severity of anaphylaxis, or if the number of antihypertensives is related to the severity of anaphylaxis. This study sought to investigate...
Publication date: December 2019Source: Annals of Allergy, Asthma & Immunology, Volume 123, Issue 6Author(s): Mitchell H. Grayson, Gailen D. Marshall
Publication date: December 2019Source: Annals of Allergy, Asthma & Immunology, Volume 123, Issue 6Author(s): Richard A. Page
Publication date: December 2019Source: Annals of Allergy, Asthma & Immunology, Volume 123, Issue 6Author(s): Wayne G. Shreffler
Publication date: December 2019Source: Annals of Allergy, Asthma & Immunology, Volume 123, Issue 6Author(s): Carmela Socolovsky, Wanda Phipatanakul
Publication date: December 2019Source: Annals of Allergy, Asthma & Immunology, Volume 123, Issue 6Author(s):
Publication date: December 2019Source: Annals of Allergy, Asthma & Immunology, Volume 123, Issue 6Author(s):
Publication date: December 2019Source: Annals of Allergy, Asthma & Immunology, Volume 123, Issue 6Author(s):
Publication date: December 2019Source: Annals of Allergy, Asthma & Immunology, Volume 123, Issue 6Author(s):
Publication date: Available online 22 November 2019Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): William W. Busse, Marc Humbert, Tmirah Haselkorn, Benjamin Ortiz, Benjamin L. Trzaskoma, Patricia Stephenson, Lorena Garcia Conde, Farid Kianifard, Stephen T. HolgateBackgroundOmalizumab improves clinical outcomes in patients with asthma. Several studies have shown lung function improvements with omalizumab; however, this has not been examined exclusively in adolescents.ObjectiveTo assess...
Publication date: Available online 21 November 2019Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Vivian Hernandez-Trujillo, John J. Oppenheimer, Stanley M. Fineman
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου