Abstract Purpose of Review This review summarizes the evidence leading towards the development of new guidelines that recommend early introduction of peanut to prevent the development of peanut allergy. It also reviews the current understanding of challenges faced with implementation of these recommendations on a widespread basis. Recent Findings ...
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Publication date: Available online 7 November 2019Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Ceazon T. Edwards, Hossam S. Alslaim, Mohanad M. Alebbini, Moses Evbuomwan, Jonathan C. Chan, Shadi Hamouri, Nathan M. Novotny
Fri Nov 08, 2019 13:52
Publication date: Available online 7 November 2019Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Stefan Hamilton, Agnieszka Dzioba, Murad HuseinIntroductionRobin sequence (RS) is a congenital set of abnormalities of the head and neck, consisting of a hypoplastic mandible (micrognathia), a tongue that is displaced posteriorly (glossoptosis), and obstruction of the airway. A clear set of diagnostic criteria for this complex condition has recently been established, but there...
Fri Nov 08, 2019 13:52
Publication date: Available online 7 November 2019Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Kenny H. Chan, Jordyn K. Dinwiddie, Gurpreet S. Ahuja, Erica C. Bennett, Matthew T. Brigger, David H. Chi, Daniel I. Choo, Michael J. Cunningham, Ravindhra G. Elluru, Carla M. Giannoni, Steven L. Goudy, Jeffrey A. Koempel, Carol J. MacArthur, Barbara Malone, Anna H. Messner, Ron B. Mitchell, Albert H. Park, Gresham T. Richter, Kristina W. Rosbe, Udayan K. ShahAbstractINTRODUCTIONAdvanced...
Fri Nov 08, 2019 13:52
Related ArticlesDoes host socio-spatial behavior lead to a fine-scale spatial genetic structure in its associated parasites? Parasite. 2019;26:64 Authors: Portanier E, Garel M, Devillard S, Duhayer J, Poirel MT, Henri H, Régis C, Maillard D, Redman E, Itty C, Michel P, Bourgoin G Abstract Gastro-intestinal nematodes, especially Haemonchus contortus, are widespread pathogenic parasites of small ruminants. Studying their spatial genetic structure is...
Fri Nov 08, 2019 17:44
Related ArticlesSTEAP2 is down-regulated in breast cancer tissue and suppresses PI3K/AKT signaling and breast cancer cell invasion in vitro and in vivo. Cancer Biol Ther. 2019 Nov 07;:1-14 Authors: Yang Q, Ji G, Li J Abstract The six-transmembrane epithelial antigen of prostate 2 (STEAP2) protein was identified in advanced prostate cancer, and is highly over-expressed in various types of cancer. This study aimed to investigate the prognostic value and...
Fri Nov 08, 2019 15:45
Related ArticlesTesticular ultrasound to stratify hormone references in a cross-sectional Norwegian study of male puberty. J Clin Endocrinol Metab. 2019 Oct 26;: Authors: Madsen A, Oehme NB, Roelants M, Bruserud IS, Eide GE, Viste K, Bjerknes R, Almås B, Rosendahl K, Sagen JV, Mellgren G, Juliusson PB Abstract CONTEXT: Testicular growth represents the best clinical variable to evaluate male puberty, but current pediatric hormone references are based...
Fri Nov 08, 2019 15:38
Related ArticlesGenetic modifiers of cystic fibrosis-related diabetes have extensive overlap with type 2 diabetes and related traits. J Clin Endocrinol Metab. 2019 Oct 19;: Authors: Aksit MA, Pace RG, Vecchio-Pagan B, Ling H, Rommens JM, Boelle PY, Guillot L, Raraigh KS, Pugh E, Zhang P, Strug LJ, Drumm ML, Knowles MR, Cutting GR, Corvol H, Blackman SM Abstract CONTEXT: Individuals with cystic fibrosis (CF) develop a distinct form of diabetes characterized...
Fri Nov 08, 2019 15:38
Related ArticlesFeasibility of differentially measuring afferent and efferent neural activity with a single nerve cuff electrode. J Neural Eng. 2019 Nov 07;: Authors: Sabetian P, Yoo PB Abstract OBJECTIVE: Advances in electrode technology have facilitated the development of neuroprostheses for restoring motor/sensory function in disabled individuals. Information extracted from whole nerve, recorded using cuffs, can provide signals that control the operation...
Fri Nov 08, 2019 15:34
Related ArticlesOptimal adjuvant radiotherapy dose for stage I, II or III Merkel cell carcinoma: an analysis of the National Cancer Database. Jpn J Clin Oncol. 2019 Nov 07;: Authors: Yusuf M, Gaskins J, Wall W, Tennant P, Bumpous J, Dunlap N Abstract BACKGROUND: We performed an analysis of the National Cancer Database to determine optimal doses of conventionally-fractionated adjuvant radiotherapy for patients with stage I/II or III Merkel cell carcinoma....
Fri Nov 08, 2019 14:30
Related ArticlesDual inhibition of EGFR and MET by Echinatin retards cell growth and induces apoptosis of lung cancer cells sensitive or resistant to gefitinib. Phytother Res. 2019 Nov 07;: Authors: Oh HN, Lee MH, Kim E, Kwak AW, Seo JH, Yoon G, Cho SS, Choi JS, Lee SM, Seo KS, Chae JI, Shim JH Abstract Patients with non-small-cell lung cancer (NSCLC) containing epidermal growth factor receptor (EGFR) amplification or sensitive mutations initially respond...
Fri Nov 08, 2019 14:28
Related ArticlesHuganpian, a traditional chinese medicine, inhibits liver cancer growth in vitro and in vivo by inducing autophagy and cell cycle arrest. Biomed Pharmacother. 2019 Nov 04;120:109469 Authors: Gao X, Wang Y, Li Y, Wang Y, Yan M, Sun H, Chen S, Pan X Abstract Huganpian (HGP), a traditional chinese medicine composed of 6 herbs, possesses excellent therapeutic effects in clinical application. In this study, we aimed to elucidate the anti-tumor...
Fri Nov 08, 2019 14:28
Related ArticlesNon-canonical Transcriptional Consequences of BET Inhibition in Cancer. Pharmacol Res. 2019 Nov 04;:104508 Authors: Letson C, Padron E Abstract Inhibition of the bromo and extra-terminal domain (BET) protein family in preclinical studies has demonstrated that BET proteins are critical for cancer progression and important therapeutic targets. Downregulation of the MYC oncogene, CDK6, BCL2 and FOSL1 are just a few examples of the effects...
Fri Nov 08, 2019 14:28
Related ArticlesSalt-Inducible Kinase inhibition suppresses acute myeloid leukemia progression in vivo. Blood. 2019 Nov 01;: Authors: Tarumoto Y, Lin S, Wang J, Milazzo JP, Xu Y, Lu B, Yang Z, Wei Y, Polyanskaya S, Wunderlich M, Gray NS, Stegmaier K, Vakoc CR Abstract Lineage-defining transcription factors (TFs) are compelling targets for leukemia therapy, yet they are among the most challenging proteins to modulate directly with small molecules. We...
Fri Nov 08, 2019 14:28
Related ArticlesAnticancer Activity of Alkynylgold(I) with P(NMe2)3 Phosphane in Mouse Colon Tumors and Human Colon Carcinoma Caco-2 Cell Line. Inorg Chem. 2019 Nov 07;: Authors: Abas E, Espallargas N, Burbello G, Mesonero JE, Rodriguez-Dieguez A, Grasa L, Laguna M Abstract New alkynylgold(I) with P(NMe2)3 (HMPT) phosphane complexes, [Au(C≡C-R)(HMPT)] (R= 4-Ph, 4-MePh, 4-OMe, 4-Br, 4-Cl, 2-py, and 3-py) have been synthesized and characterized, including...
Fri Nov 08, 2019 14:28
Related ArticlesSNHG16 as the miRNA let-7b-5p sponge facilitates the G2/M and epithelial-mesenchymal transition by regulating CDC25B and HMGA2 expression in hepatocellular carcinoma. J Cell Biochem. 2019 Nov 07;: Authors: Li S, Peng F, Ning Y, Jiang P, Peng J, Ding X, Zhang J, Jiang T, Xiang S Abstract Long noncoding RNAs (lncRNAs) play crucial roles in hepatocellular carcinoma (HCC). However, the underlying molecular mechanisms of small nucleolar RNA...
Fri Nov 08, 2019 14:28
Related ArticlesPossible Selective Cytotoxicity of Vanadium Complex on Breast Cancer Cells Involving Pathophysiological Pathways. Anticancer Agents Med Chem. 2019 Oct 24;: Authors: El-Shafey ES, Elsherbiny ES Abstract BACKGROUND: Triple-Negative Breast Cancers (TNBC) are among the most aggressive and therapy resistant breast tumors. Development of new treatment strategies that target pathways involved in cancer cells resistance is an attractive candidate...
Fri Nov 08, 2019 14:28
Related ArticlesMolecular Docking Study, Cytotoxicity, Cell Cycle Arrest and Apoptotic Induction of Novel Chalcones Incorporating Thiadiazolyl Isoquinoline in Cervical Cancer. Anticancer Agents Med Chem. 2019 Oct 24;: Authors: Tantawy MA, Sroor FM, Mohamed MF, El-Naggar ME, Saleh FM, Hassaneen HM, Abdelhamid IA Abstract BACKGROUND: Chalcones are naturally occurring compounds found in various plant species which are widely used for traditional popular...
Fri Nov 08, 2019 14:28
Related ArticlesEpimagnolin targeting on an active pocket of mammalian target of rapamycin suppressed cell transformation and colony growth of lung cancer cells. Mol Carcinog. 2019 07;58(7):1221-1233 Authors: Yoo SM, Lee CJ, Kang HC, Lee HS, Lee JY, Kim KD, Kim DJ, An HJ, Cho YY Abstract Mammalian target of rapamycin (mTOR) has a pivotal role in carcinogenesis and cancer cell proliferation in diverse human cancers. In this study, we observed that epimagnolin,...
Fri Nov 08, 2019 13:27
Related ArticlesSmall RNA-induced INTS6 gene up-regulation suppresses castration-resistant prostate cancer cells by regulating β-catenin signaling. Cell Cycle. 2018;17(13):1602-1613 Authors: Chen H, Shen HX, Lin YW, Mao YQ, Liu B, Xie LP Abstract Small RNAs play an important role in gene regulatory networks. The gene suppressive effect of small RNAs was previously the dominant focus of studies, but during the recent decade, small RNA-induced gene activation...
Fri Nov 08, 2019 13:27
Related ArticlesA new inhibitor of glucose-6-phosphate dehydrogenase blocks pentose phosphate pathway and suppresses malignant proliferation and metastasis in vivo. Cell Death Dis. 2018 05 01;9(5):572 Authors: Mele L, Paino F, Papaccio F, Regad T, Boocock D, Stiuso P, Lombardi A, Liccardo D, Aquino G, Barbieri A, Arra C, Coveney C, La Noce M, Papaccio G, Caraglia M, Tirino V, Desiderio V Abstract Pentose phosphate pathway (PPP) is a major glucose metabolism...
Fri Nov 08, 2019 13:27
Related ArticlesTSPY1 suppresses USP7-mediated p53 function and promotes spermatogonial proliferation. Cell Death Dis. 2018 05 01;9(5):542 Authors: Shen Y, Tu W, Liu Y, Yang X, Dong Q, Yang B, Xu J, Yan Y, Pei X, Liu M, Xu W, Yang Y Abstract Testis-specific protein Y-linked 1 (TSPY1) is expressed predominantly in adult human spermatogonia and functions in the process of spermatogenesis; however, our understanding of the underlying mechanism is limited....
Fri Nov 08, 2019 13:27
Related ArticlesInhibition of cancer progression by a novel trans-stilbene derivative through disruption of microtubule dynamics, driving G2/M arrest, and p53-dependent apoptosis. Cell Death Dis. 2018 05 01;9(5):448 Authors: Parida PK, Mahata B, Santra A, Chakraborty S, Ghosh Z, Raha S, Misra AK, Biswas K, Jana K Abstract Resveratrol, a trans-stilbene polyphenolic compound and its synthetic analogs are widely used bioactive molecules due to their remarkable...
Fri Nov 08, 2019 13:27
Related ArticlesA Case of Primary Central Nervous System Vasculitis That Worsened Despite Early Corticosteroid Therapy. Brain Tumor Res Treat. 2019 Oct;7(2):164-167 Authors: Yoon SY, Park KS, Park SH, Park JY Abstract Primary central nervous system vasculitis (PCNSV) is rare, and the diagnosis is difficult to make because of its variable radiologic expressions. Early corticosteroid therapy often is effective. Herein we report the case of a 56-year-old...
Fri Nov 08, 2019 13:26
Related ArticlesIntratumoral Hemorrhage of the Cervical Spinal Schwannoma Presenting: Acute Quadriparesis. Brain Tumor Res Treat. 2019 Oct;7(2):160-163 Authors: Jung GS, Lee YM, Kim YZ, Kim JS Abstract Schwannomas are the most common extramedullary spinal tumors, with chronic progressive symptoms being the most common presenting features. The acute hemorrhagic onset of a spinal schwannoma is a rare occurrence. Here, we report the case of a 37-year-old...
Fri Nov 08, 2019 13:26
Related ArticlesAngioleiomyoma in the Orbital Apex: A Case Report. Brain Tumor Res Treat. 2019 Oct;7(2):156-159 Authors: Lee B, Park SJ, Moon JH, Kim SH, Chang JH, Kim SH, Kim EH Abstract A 56-year woman presented eyeball pain and blurred vision. MRI revealed a small well-delineated solid tumor in the apex of right orbit with optic nerve compression. Intraoperatively, the tumor was found very fibrous, hypervascular and adhesive to surrounding structures....
Fri Nov 08, 2019 13:26
Related ArticlesLateral Ventricular Meningioma Presenting with Intraventricular Hemorrhage. Brain Tumor Res Treat. 2019 Oct;7(2):151-155 Authors: Moon JS, Cha SH, Cho WH Abstract A 35-year-old female visited emergency department for a sudden onset of headache with vomiting after management for abortion at local department. Neurological examination revealed drowsy mentality without focal neurological deficits. CT showed 3.2×3.4 cm hyperdense intraventricular...
Fri Nov 08, 2019 13:26
Related ArticlesA Case of Sporadic Suprasellar Hemangioblastoma Mimicking Meningioma. Brain Tumor Res Treat. 2019 Oct;7(2):147-150 Authors: Kang BM, Youn SM Abstract Hemangioblastoma (HBL) in the suprasellar region is very rare and a few cases have been reported. Suprasellar HBL without von Hippel-Lindau disease is much rarer. A 76-year old male patient presented progressively deteriorating visual disturbance. MRI demonstrated solid suprasellar mass...
Fri Nov 08, 2019 13:26
Related ArticlesFound at Old Age and Continuously Growing WHO Grade II Fourth Ventricle Ependymoma: A Case Report. Brain Tumor Res Treat. 2019 Oct;7(2):141-146 Authors: Park M, Hong EK, Lee SH, Gwak HS Abstract A 74-year-old woman presented with a month-long nausea and vomiting, then she could not take a meal. She had found an asymptomatic 4th ventricular mass 6 year ago as a preoperative work-up for ovarian cancer. And during the yearly follow-up, the...
Fri Nov 08, 2019 13:26
Related ArticlesDiscordance of Epidermal Growth Factor Receptor Mutation between Brain Metastasis and Primary Non-Small Cell Lung Cancer. Brain Tumor Res Treat. 2019 Oct;7(2):137-140 Authors: Kim KM, Lee SH, Kim SM, Kim NY, Gwak HS, Shin SH, Kwon JW, Yoo H Abstract BACKGROUND: The aim of this study was to compare epidermal growth factor receptor (EGFR) mutations between non-small cell lung cancer (NSCLC) and corresponding brain metastases (BMs) in Korea...
Fri Nov 08, 2019 13:26
Related ArticlesThe Effect of Pain Reduction during Headframe Fixation for Stereotactic Radiosurgery by the Preceded Local Anesthesia under the Needle Cap Guidance. Brain Tumor Res Treat. 2019 Oct;7(2):132-136 Authors: Kim DH, Cho WH, Hur BI, Cha SH, Lee SW, Choi CH Abstract BACKGROUND: Gamma knife radiosurgery (GKRS) has become a major alternative in the neurosurgical field. However, many patients complained of considerable discomfort during the fixation...
Fri Nov 08, 2019 13:26
Related ArticlesRacial Differences in Hospital Stays among Patients Undergoing Craniotomy for Tumour Resection at a Single Academic Hospital. Brain Tumor Res Treat. 2019 Oct;7(2):122-131 Authors: Sheppard JP, Lagman C, Romiyo P, Nguyen T, Azzam D, Alkhalid Y, Duong C, Yang I Abstract BACKGROUND: Racial differences in American patients undergoing brain tumour surgery remain poorly characterized within urban medical centres. Our objective was to assess...
Fri Nov 08, 2019 13:26
Related ArticlesDemographic and Socioeconomic Factors for Renouncing Further Active Therapy for Patients with Brain Metastasis of Non-Small Cell Lung Cancer. Brain Tumor Res Treat. 2019 Oct;7(2):112-121 Authors: Jung G, Kim SH, Kim TG, Kim YZ Abstract BACKGROUND: As patients with brain metastasis (BM) of non-small cell lung cancer (NSCLC) have dismal prognosis, some of them decide to discontinue further treatment for BM. The objective of this study was...
Fri Nov 08, 2019 13:26
Related ArticlesExperience Profiling of Fluorescence-Guided Surgery II: Non-Glioma Pathologies. Brain Tumor Res Treat. 2019 Oct;7(2):105-111 Authors: Ji SY, Kim JW, Park CK Abstract BACKGROUND: Only sporadic reports of fluorescence-guided surgery (FGS) have been published for non-glioma conditions. In this study, we focus on epidemiological data of fluorescence patterns and report the diverse experiences of FGS in non-gliomas. METHODS: During...
Fri Nov 08, 2019 13:26
Related ArticlesExperience Profiling of Fluorescence-Guided Surgery I: Gliomas. Brain Tumor Res Treat. 2019 Oct;7(2):98-104 Authors: Ji SY, Kim JW, Park CK Abstract BACKGROUND: Numerous studies reported a usefulness of 5-aminolevulinic acid (5-ALA) fluorescence-guided surgery (FGS) in high grade gliomas. However, fluorescence patterns and intensities are variable among gliomas. In this study, we report our extensive experience with FGS in various gliomas,...
Fri Nov 08, 2019 13:26
Related ArticlesSurvival and Prognosis of Patients with Pilocytic Astrocytoma: A Single-Center Study. Brain Tumor Res Treat. 2019 Oct;7(2):92-97 Authors: Park JH, Jung N, Kang SJ, Kim HS, Kim E, Lee HJ, Jung HR, Choe M, Shim YJ Abstract BACKGROUND: Pilocytic astrocytoma (PA) is a brain tumor that is relatively more common in children and young adults. METHODS: We retrospectively reviewed the medical records of patients with PA treated at a single...
Fri Nov 08, 2019 13:26
Related ArticlesEfficacy of Slow Rate Ventriculolumbar Perfusion Chemotherapy for Leptomeningeal Carcinomatosis: Interim Result of a Phase II Study. Brain Tumor Res Treat. 2019 Oct;7(2):85-91 Authors: Choi YH, Gwak HS, Joo J, Kwon JW, Shin SH, Yoo H, Lee JH, Youn JH Abstract BACKGROUND: To evaluate the efficacy of modified ventriculolumbar perfusion (VLP) chemotherapy with methotrexate on leptomeningeal carcinomatosis in terms of symptomatic response...
Fri Nov 08, 2019 13:26
Related ArticlesThe Korean Society for Neuro-Oncology (KSNO) Guideline for WHO Grade II Cerebral Gliomas in Adults: Version 2019.01. Brain Tumor Res Treat. 2019 Oct;7(2):74-84 Authors: Kim YZ, Kim CY, Wee CW, Roh TH, Hong JB, Oh HJ, Kang SG, Kang SH, Kong DS, Kim SH, Kim SH, Kim SH, Kim YJ, Kim EH, Kim IA, Kim HS, Park JS, Park HJ, Song SW, Sung KS, Yang SH, Yoon WS, Yoon HI, Lee J, Lee ST, Lee SW, Lee YS, Lim J, Chang JH, Jung TY, Jung HL, Cho JH, Choi SH, Choi HS, Lim...
Fri Nov 08, 2019 13:26
Related ArticlesThe Korean Society for Neuro-Oncology (KSNO) Guideline for WHO Grade III Cerebral Gliomas in Adults: Version 2019.01. Brain Tumor Res Treat. 2019 Oct;7(2):63-73 Authors: Kim YZ, Kim CY, Lim J, Sung KS, Lee J, Oh HJ, Kang SG, Kang SH, Kong DS, Kim SH, Kim SH, Kim SH, Kim YJ, Kim EH, Kim IA, Kim HS, Roh TH, Park JS, Park HJ, Song SW, Yang SH, Yoon WS, Yoon HI, Lee ST, Lee SW, Lee YS, Wee CW, Chang JH, Jung TY, Jung HL, Cho JH, Choi SH, Choi HS, Hong JB,...
Fri Nov 08, 2019 13:26
Publication date: Available online 7 November 2019Source: European Journal of CancerAuthor(s): Wiebke Sondermann, Jochen Sven Utikal, Alexander H. Enk, Dirk Schadendorf, Joachim Klode, Axel Hauschild, Michael Weichenthal, Lars E. French, Carola Berking, Bastian Schilling, Sebastian Haferkamp, Stefan Fröhling, Christof von Kalle, Titus J. Brinker
Fri Nov 08, 2019 13:26
Related ArticlesElectronic spectroscopic characterization of the formation of iron(III) metal complexes: The 8-HydroxyQuinoline as ligand case study. J Inorg Biochem. 2019 Oct 26;203:110864 Authors: Huyen Vu T, Serradji N, Seydou M, Brémond É, Ha-Duong NT Abstract Synthetic siderophores derivated from 8-HydroxyQuinoline (HQ) present various biological and pharmacological activities, such as anti-neurodegenerative or anti-oxydative. However, their affinity...
Fri Nov 08, 2019 14:26
Related ArticlesEarly insight into the potential contribution of aluminum to neurodegeneration - A tribute to the research work of Robert D. Terry, Igor Klatzo, Henryk M. Wisniewski and Donald R.C. Mclachlan. J Inorg Biochem. 2019 Sep 12;203:110860 Authors: Hill JM, Percy ME, Lukiw WJ Abstract The first successful attempt to obtain purified aluminum metal was accomplished by the Danish physicist and chemist Hans Christian Orsted in 1824, however it was...
Fri Nov 08, 2019 14:26
Related ArticlesZn(II) and Co(II) derivatives anchored with scorpionate precursor: Antiproliferative evaluation in human cancer cell lines. J Inorg Biochem. 2019 Oct 23;202:110881 Authors: Das K, Datta A, Frontera A, Wen YS, Roma-Rodrigues C, Raposo LR, Fernandes AR, Hung CH Abstract A 'scorpionate' type precursor [bdtbpza = bis(3,5-di-t-butylpyrazol-1-yl)acetate] has been employed to synthesize two mononuclear ZnII and CoII derivatives, namely [Zn(bdtbpza)2...
Fri Nov 08, 2019 14:26
Related ArticlesThe metal-binding properties of the long chaplin from Streptomyces mobaraensis: A bioinformatic and biochemical approach. J Inorg Biochem. 2019 Oct 21;202:110878 Authors: Anderl A, Kolmar H, Fuchsbauer HL Abstract Chaplins are amphiphilic proteins coating the surface of aerial hyphae under formation of amyloid-like rodlet layers in streptomycetes. The long chaplin from Streptomyces mobaraensis, Sm-Chp1, harbors extended histidine-rich...
Fri Nov 08, 2019 14:26
Related ArticlesEpileptiform activity promotes decreasing of Ca2+ conductivity of NMDARs, AMPARs, KARs, and voltage-gated calcium channels in Mg2+-free model. Epilepsy Res. 2019 Oct 23;158:106224 Authors: Gaidin SG, Zinchenko VP, Teplov IY, Tuleukhanov ST, Kosenkov AM Abstract NMDA, AMPA, and kainate receptors are the principal excitatory receptors in the brain. These receptors have been considered as the main targets in the treatment of epilepsy in...
Fri Nov 08, 2019 15:20
Related ArticlesPsychogenic nonepileptic seizures: Comparing what South African healthcare providers communicate to patients at the point of diagnosis against international guidelines. Epilepsy Behav. 2019 Nov 04;101(Pt A):106399 Authors: Hartwig L, Pretorius C Abstract The process of communicating a diagnosis of psychogenic nonepileptic seizures (PNES) has been widely studied internationally and found to be an important factor in the reduction of symptoms...
Fri Nov 08, 2019 15:20
Related ArticlesGenetic backgrounds have unique seizure response profiles and behavioral outcomes following convulsant administration. Epilepsy Behav. 2019 Nov 04;101(Pt A):106547 Authors: Copping NA, Adhikari A, Petkova SP, Silverman JL Abstract Three highly utilized strains of mice, common for preclinical genetic studies, were evaluated for seizure susceptibility and behavioral outcomes common to the clinical phenotypes of numerous psychiatric disorders...
Fri Nov 08, 2019 15:20
Related ArticlesNetwork connectivity separate from the hypothesized irritative zone correlates with impaired cognition and higher rates of seizure recurrence. Epilepsy Behav. 2019 Nov 04;101(Pt A):106585 Authors: Neal EG, Di L, Reale-Caldwell A, Maciver S, Schoenberg MR, Vale FL Abstract INTRODUCTION: Surgery remains an essential option for the treatment of medically intractable temporal lobe epilepsy (TLE). However, only 66% of patients achieve postoperative...
Fri Nov 08, 2019 15:20
Related ArticlesTreatment with brivaracetam in children - The experience of a pediatric epilepsy center. Epilepsy Behav. 2019 Nov 04;101(Pt A):106541 Authors: Nissenkorn A, Tzadok M, Bar-Yosef O, Ben-Zeev B Abstract INTRODUCTION: The new anticonvulsant brivaracetam is a levetiracetam analog which binds to the synaptic vesicle protein 2A, and inhibits excitatory neurotransmitters' release. Brivaracetam was Food and Drug Administration (FDA) and European...
Fri Nov 08, 2019 15:20
Related ArticlesEpisodic simulation and empathy in older adults and patients with unilateral medial temporal lobe excisions. Neuropsychologia. 2019 Nov 04;:107243 Authors: Sawczak C, McAndrews MP, Gaesser B, Moscovitch M Abstract Recent work shows that vividly imagining oneself helping others in situations of need (episodic simulation) increases one's willingness to help. The mechanisms underlying this effect are unclear, though it is known that the...
Fri Nov 08, 2019 15:20
Parental Attitudes Toward Deep Brain Stimulation in Adolescents with Treatment-Resistant Conditions.
Related ArticlesParental Attitudes Toward Deep Brain Stimulation in Adolescents with Treatment-Resistant Conditions. J Child Adolesc Psychopharmacol. 2019 Nov 07;: Authors: Storch EA, Cepeda SL, Lee E, Goodman SLV, Robinson AD, De Nadai AS, Schneider SC, Sheth SA, Torgerson L, Lázaro-Muñoz G Abstract Objective: To examine parent's perceptions of deep brain stimulation (DBS) and whether DBS is perceived to be a viable and safe treatment for their adolescent...
Fri Nov 08, 2019 15:20
Related ArticlesRecessive GM3 synthase deficiency: Natural history, biochemistry, and therapeutic frontier. Mol Genet Metab. 2019 04;126(4):475-488 Authors: Bowser LE, Young M, Wenger OK, Ammous Z, Brigatti KW, Carson VJ, Moser T, Deline J, Aoki K, Morlet T, Scott EM, Puffenberger EG, Robinson DL, Hendrickson C, Salvin J, Gottlieb S, Heaps AD, Tiemeyer M, Strauss KA Abstract GM3 synthase, encoded by ST3GAL5, initiates synthesis of all downstream cerebral...
Fri Nov 08, 2019 13:16
Related ArticlesCorrelation between Nurr1 expression and drug resistance in the brain of rats with epilepsy. Eur Rev Med Pharmacol Sci. 2018 03;22(5):1506-1513 Authors: Li HY, Liu F, Wang HR Abstract OBJECTIVE: To investigate the correlation between nuclear receptor related 1 (Nurr1) expression and drug resistance in the brain of rats with epilepsy. MATERIALS AND METHODS: A total of 60 adult male Sprague-Dawley rats were selected, and the animal...
Fri Nov 08, 2019 13:16
Related ArticlesBioactive Small Molecules: Promising Novel Therapies in Cardiovascular Diseases - PART II. Curr Top Med Chem. 2019;19(21):1877 Authors: Yu Y AbstractPMID: 31696800 [PubMed - in process]
Fri Nov 08, 2019 15:15
Related ArticlesTargeting Protein-Protein Interaction with Covalent Small-Molecule Inhibitors. Curr Top Med Chem. 2019;19(21):1872-1876 Authors: Li B, Rong D, Wang Y Abstract PPIs are involved in diverse biochemical events and perform their functions through the formation of protein-protein complexes or PPI networks. The large and flat interacting surfaces of PPIs make discovery of small-molecule modulators a challenging task. New strategies and more...
Fri Nov 08, 2019 15:15
Related ArticlesToxins of Animal Venoms and Inhibitors: Molecular and Biotechnological Tools Useful to Human and Animal Health. Curr Top Med Chem. 2019;19(21):1868-1871 Authors: Soares AM, Zuliani JP AbstractPMID: 31696798 [PubMed - in process]
Fri Nov 08, 2019 15:15
Related ArticlesBioactive Small Molecules: Promising Novel Therapies in Cardiovascular Diseases - PART I. Curr Top Med Chem. 2019;19(20):1789 Authors: Yu Y AbstractPMID: 31696796 [PubMed - in process]
Fri Nov 08, 2019 15:15
Related ArticlesInternational Pediatric Otolaryngology Group (IPOG): Juvenile-onset recurrent respiratory papillomatosis consensus recommendations. Int J Pediatr Otorhinolaryngol. 2019 Sep 28;128:109697 Authors: Lawlor C, Balakrishnan K, Bottero S, Boudewyns A, Campisi P, Carter J, Cheng A, Cocciaglia A, DeAlarcon A, Derkay C, Fayoux P, Hart C, Hartnick C, LeBoulanger N, Moreddu E, Muntz H, Nicollas R, Peer S, Pransky S, Rahbar R, Russell J, Rutter M, Seedat R, Sidell...
Fri Nov 08, 2019 15:12
Related ArticlesA novel rat model for tracheal mucosal damage assessment of following long term intubation. Int J Pediatr Otorhinolaryngol. 2019 Oct 24;128:109738 Authors: Jahshan F, Ertracht O, Eisenbach N, Daoud A, Sela E, Atar S, Abu Ammar A, Gruber M Abstract OBJECTIVE: Tracheal mucosal damage is a well-known complication of endo-tracheal intubation and animal models are essential for studying the underlying cellular injury cascade. The novel rat...
Fri Nov 08, 2019 15:12
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