Related ArticlesRisk and Rate of Occult Contralateral Nodal Disease in Surgically Treated Patients With Human Papillomavirus-Related Squamous Cell Carcinoma of the Base of the Tongue. JAMA Otolaryngol Head Neck Surg. 2019 Nov 07;: Authors: Last AS, Pipkorn P, Chen S, Kallogjeri D, Zenga J, Rich JT, Paniello R, Zevallos J, Chernock R, Adkins D, Oppelt P, Gay H, Daly M, Thorstad W, Jackson RS Abstract Importance: The optimal treatment strategy for patients...
Fri Nov 08, 2019 14:18
Related ArticlesA Technology-Assisted, Brief Mind-Body Intervention to Improve the Waiting Room Experience for Chemotherapy Patients: Randomized Quality Improvement Study. JMIR Cancer. 2019 Nov 07;5(2):e13217 Authors: Bao T, Deng G, DeMarzo LA, Zhi WI, DeRito JL, Blinder V, Chen C, Li QS, Green J, Pendleton E, Mao JJ Abstract BACKGROUND: Patients waiting for chemotherapy can experience stress, anxiety, nausea, and pain. Acupressure and meditation have...
Fri Nov 08, 2019 14:18
Related ArticlesPannexin 1 activation and inhibition is permeant-selective. J Physiol. 2019 Nov 07;: Authors: Nielsen BS, Toft-Bertelsen TL, Lolansen SD, Anderson C, Nielsen MS, Thompson RJ, MacAulay N Abstract KEY POINTS: •The large-pore channel pannexin 1 (Panx1) is expressed in many cell types and can open upon different, yet not fully established, stimuli. •Panx1 permeability is often inferred from channel permeability to fluorescent dyes, but it...
Fri Nov 08, 2019 15:13
Related ArticlesImmediate brain plasticity after one hour of brain-computer interface (BCI). J Physiol. 2019 Nov 06;: Authors: Nierhaus T, Vidaurre C, Sannelli C, Mueller KR, Villringer A Abstract KEY POINTS: Two groups of inexperienced brain-computer interface users underwent a purely mental EEG-BCI session that rapidly impacted on their brain. Modulations in structural and functional MRI were found after only 1 h of BCI training. Two different types...
Fri Nov 08, 2019 15:13
Related ArticlesGlobal REACH 2018: The influence of acute and chronic hypoxia on cerebral haemodynamics and related functional outcomes during cold and heat stress. J Physiol. 2019 Nov 07;: Authors: Gibbons TD, Tymko MM, Thomas KN, Wilson LC, Stembridge M, Caldwell HG, Howe CA, Hoiland RL, Akerman AP, Dawkins TG, Patrician A, Coombs GB, Gasho C, Stacey BS, Ainslie PN, Cotter JD Abstract KEY POINTS: •Thermal and hypoxic stress commonly coexist in environmental,...
Fri Nov 08, 2019 15:13
Related ArticlesInsulin-induced membrane permeability to glucose in human muscles at rest and following exercise. J Physiol. 2019 Nov 07;: Authors: McConell GK, Sjøberg KA, Ceutz F, Gliemann L, Nyberg MP, Hellsten Y, Frøsig C, Kiens B, Wojtaszewski JFP, Richter EA Abstract KEY POINTS: Increased insulin action is an important component of the health benefits of exercise, but its regulation is complex and not fully elucidated. Previous studies of insulin-stimulated...
Fri Nov 08, 2019 15:13
Related ArticlesMaximum voluntary retrusion or habitual bite position for mandibular advancement assessment in the treatment of obstructive sleep apnoea patients. J Oral Rehabil. 2019 Nov 07;: Authors: Ippolito DR, Stipa C, Cameli M, Sorrenti G, Pelligra I, Alessandri-Bonetti G Abstract BACKGROUND: There is no consensus on whether the range of mandibular advancement for the construction of mandibular advancement devices in obstructive sleep apnoea (OSA)...
Fri Nov 08, 2019 14:42
Related ArticlesTargeting cyclooxygenase by indomethacin decelerates progression of acute lymphoblastic leukemia in a xenograft model. Blood Adv. 2019 Nov 12;3(21):3181-3190 Authors: Richartz N, Duthil E, Ford A, Naderi EH, Bhagwat S, Gilljam KM, Burman MM, Ruud E, Blomhoff HK, Skah S Abstract Acute lymphoblastic leukemia (ALL) develops in the bone marrow in the vicinity of stromal cells known to promote tumor development and treatment resistance. We...
Fri Nov 08, 2019 14:42
Related ArticlesAssociation Between Head and Neck Cancers and Polymorphisms 869T/C, 509C/T, and 915G/C of the Transforming Growth Factor-β1 Gene: A Meta-Analysis of Case-Control Studies. Med Sci Monit. 2019 Nov 07;25:8389-8402 Authors: Qu Y, Feng J, Wang L, Wang H, Liu H, Sun X, Li J, Yu H Abstract BACKGROUND Worldwide, head and neck cancers are the eighth most common malignancy. Single nucleotide polymorphisms (SNPs) are associated with susceptibility...
Fri Nov 08, 2019 14:42
Related ArticlesThe Pectoralis Major Island Flap: Short Scar Modified Muscle-Sparing Harvesting Technique Improves Aesthetic Outcome in Reconstructive Head and Neck Surgery. ORL J Otorhinolaryngol Relat Spec. 2019 Nov 07;:1-11 Authors: Rauchenwald T, Dejaco D, Morandi EM, Djedovic G, Wolfram D, Riechelmann H, Pierer G Abstract BACKGROUND: Pectoralis major flap reconstruction is often associated with large unappealing scars in head-neck surgery. We recently...
Fri Nov 08, 2019 14:42
Related Articles[A Case of Dedifferentiated Liposarcoma of the Spermatic Cord]. Hinyokika Kiyo. 2019 Oct;65(10):429-434 Authors: Tobiume M, Aoki S, Yamada Y, Hara K, Muramatsu H, Nishikawa G, Ono K, Nakamura K Abstract Liposarcomas are most commonly found in the extremities, in the retroperitoneum and, less often, in the head and neck area. The spermatic cord is a rare site of origin, accounting for about 4-7% of all liposarcomas. We report a case of...
Fri Nov 08, 2019 14:42
Related ArticlesInvolvement of extracellular vesicles in the macrophage-tumor cell communication in head and neck squamous cell carcinoma. PLoS One. 2019;14(11):e0224710 Authors: Bellmunt ÀM, López-Puerto L, Lorente J, Closa D Abstract BACKGROUND: Exosomes are cell-derived vesicles that mediate cellular communication in health and multiple diseases, including cancer. However, its role in head and neck cancer has been poorly defined. Here, we investigated...
Fri Nov 08, 2019 14:42
Related ArticlesAssessing reliability of intra-tumor heterogeneity estimates from single sample whole exome sequencing data. PLoS One. 2019;14(11):e0224143 Authors: Abécassis J, Hamy AS, Laurent C, Sadacca B, Bonsang-Kitzis H, Reyal F, Vert JP Abstract Tumors are made of evolving and heterogeneous populations of cells which arise from successive appearance and expansion of subclonal populations, following acquisition of mutations conferring them a selective...
Fri Nov 08, 2019 14:42
Related ArticlesEffects of Language History on Sentence Recognition in Noise or Two-Talker Speech: Monolingual, Early Bilingual, and Late Bilingual Speakers of English. Am J Audiol. 2019 Nov 07;:1-12 Authors: Regalado D, Kong J, Buss E, Calandruccio L Abstract Purpose Language history is an important factor in masked speech recognition. Listeners who acquire the target language later in life perform more poorly than native speakers. However, there are...
Fri Nov 08, 2019 14:42
Related ArticlesPhase-sensitive fluorescence detector for parathyroid glands during thyroidectomy: a preliminary report. J Biophotonics. 2019 Nov 07;:e201960078 Authors: Kim Y, Kim SW, Lee KD, Ahn YC Abstract Despite advances in medical technology, the parathyroid glands are still damaged during thyroid surgery. Our previous studies exploring methods for locating the parathyroid glands using autofluorescence have limitations, such as turning off the...
Fri Nov 08, 2019 14:42
Related ArticlesThe 2019 AHNS Annual Meeting Presidential Address-The Future of AHNS in a Competitive Environment. JAMA Otolaryngol Head Neck Surg. 2019 Nov 07;: Authors: Hanna E PMID: 31697364 [PubMed - as supplied by publisher]
Fri Nov 08, 2019 14:42
Related ArticlesCost-effectiveness of Stapedectomy vs Hearing Aids in the Treatment of Otosclerosis. JAMA Otolaryngol Head Neck Surg. 2019 Nov 07;: Authors: Gillard DM, Harris JP Abstract Importance: Otosclerosis can be managed through surgical treatment, such as stapedectomy, or through hearing amplification with hearing aids. To our knowledge, there has been no cost-effectiveness analysis of these 2 treatment methods. Objective: To determine...
Fri Nov 08, 2019 14:42
Related ArticlesSupraomohyoid Neck Dissection for the Clinically Node-Negative Neck in Oral Cavity Squamous Cell Carcinoma: Time to Change Practices? JAMA Otolaryngol Head Neck Surg. 2019 Nov 07;: Authors: Subash A PMID: 31697346 [PubMed - as supplied by publisher]
Fri Nov 08, 2019 14:42
Investigation on ciliary functionality of different airway epithelial cell lines in 3D cell culture.
Related ArticlesInvestigation on ciliary functionality of different airway epithelial cell lines in 3D cell culture. Tissue Eng Part A. 2019 Nov 07;: Authors: Lodes NT, Seidensticker K, Perniss A, Nietzer SL, Oberwinkler H, May T, Walles T, Hebestreit H, Hackenberg S, Steinke M Abstract 3D respiratory tissue models have been generated using, for example, human primary airway epithelial cells (hAEC) or respective cell lines. To investigate ciliopathies,...
Fri Nov 08, 2019 14:42
Related ArticlesWhat is the oncologic safety of using the submental flap to reconstruct oral cavity cancer defects? Laryngoscope. 2019 11;129(11):2443-2444 Authors: Chang BA, Asarkar AA, Nathan CO PMID: 31424567 [PubMed - indexed for MEDLINE]
Fri Nov 08, 2019 13:11
Related ArticlesTLR4 in skin cancer: From molecular mechanisms to clinical interventions. Mol Carcinog. 2019 07;58(7):1086-1093 Authors: Dickinson SE, Wondrak GT Abstract The health and economic burden imposed by skin cancer is substantial, creating an urgent need for the development of improved molecular strategies for its prevention and treatment. Cutaneous exposure to solar ultraviolet (UV) radiation is a causative factor in skin carcinogenesis, and...
Fri Nov 08, 2019 13:11
Related ArticlesRevisiting age-related admission following tonsillectomy in the pediatric population. Laryngoscope. 2019 Nov;129(11):E389-E394 Authors: Evans SS, Cho DY, Richman J, Kulbersh B Abstract OBJECTIVES/HYPOTHESIS: The objectives of this study were to examine patient outcomes using a 36-month age cutoff as a strict admission criterion following tonsillectomy, and review the safety and determine the plausibility of same-day discharge of children...
Fri Nov 08, 2019 13:11
Hypoglossal nerve stimulation in three adults with down syndrome and severe obstructive sleep apnea.
Related ArticlesHypoglossal nerve stimulation in three adults with down syndrome and severe obstructive sleep apnea. Laryngoscope. 2019 Nov;129(11):E402-E406 Authors: Li C, Boon M, Ishman SL, Suurna MV Abstract We present three adults with Down syndrome and obstructive sleep apnea (OSA) treated with hypoglossal nerve stimulation. The average age of these three males was 37.3 years. All patients had severe OSA on polysomnography. Postimplantation titration...
Fri Nov 08, 2019 13:11
Related ArticlesNovel therapies hijack the blood-brain barrier to eradicate glioblastoma cancer stem cells. Carcinogenesis. 2019 03 12;40(1):2-14 Authors: Vengoji R, Ponnusamy MP, Rachagani S, Mahapatra S, Batra SK, Shonka N, Macha MA Abstract Glioblastoma (GBM) is amongst the most aggressive brain tumors with a dismal prognosis. Despite significant advances in the current multimodality therapy including surgery, postoperative radiotherapy (RT) and temozolomide...
Fri Nov 08, 2019 13:11
STAT3- and GSK3β-mediated Mcl-1 regulation modulates TPF resistance in oral squamous cell carcinoma.
Related ArticlesSTAT3- and GSK3β-mediated Mcl-1 regulation modulates TPF resistance in oral squamous cell carcinoma. Carcinogenesis. 2019 03 12;40(1):173-183 Authors: Maji S, Shriwas O, Samal SK, Priyadarshini M, Rath R, Panda S, Das Majumdar SK, Muduly DK, Dash R Abstract Cisplatin alone or in combination with 5FU (5-fluorouracil) and docetaxel (TPF) are common regimen chemotherapeutics for treatment of advanced oral squamous cell carcinoma (OSCC)....
Fri Nov 08, 2019 13:11
Related ArticlesMortality and long-term quality of life after percutaneous tracheotomy in Intensive Care Unit: a prospective observational study. Minerva Anestesiol. 2018 09;84(9):1024-1031 Authors: Vargas M, Sutherasan Y, Brunetti I, Micalizzi C, Insorsi A, Ball L, Folentino M, Sileo R, De Lucia A, Cerana M, Accattatis A, De Lisi D, Gratarola A, Mora F, Peretti G, Servillo G, Pelosi P Abstract BACKGROUND: Quality of life and mortality after percutaneous...
Fri Nov 08, 2019 13:11
Related ArticlesMatrix metalloproteinase 1: a better biomarker for squamous cell carcinoma by multiple microarray analyses. G Ital Dermatol Venereol. 2019 Jun;154(3):327-337 Authors: Zheng LQ, Wang R, Chi SM, Li CX Abstract BACKGROUND: The present study aimed to validate MMP1 role in the development of squamous cell carcinoma (SCC) by bioinformatics methods. METHODS: Gene expression data of 10 GSE series (5 HNSCCs and 5 cSCCs) were obtained...
Fri Nov 08, 2019 13:11
Related ArticlesUse of ustekinumab in five psoriatic patients with hepatitis B virus infection. G Ital Dermatol Venereol. 2019 Jun;154(3):376-377 Authors: Piaserico S, Conti A, Coati I, Galdo G, Bernabucci V, Zanca A, Drabeni M, Masutti F, Musumeci ML, Alberti A, Russo FP PMID: 28712266 [PubMed - indexed for MEDLINE]
Fri Nov 08, 2019 13:11
Related ArticlesReview of treatments for generalized pustular psoriasis manuscript. J Dermatolog Treat. 2019 Nov 07;:1-13 Authors: Kearns DG, Chat VS, Zang PD, Han G, Wu JJ Abstract Background: Generalized pustular psoriasis (GPP) is an uncommon variant of psoriasis that is characterized clinically by sterile pustule formation superimposed over inflamed, erythematous skin.Methods: In June 2019, we conducted a systematic search of the PubMed Medline database...
Fri Nov 08, 2019 15:04
Related ArticlesFractional CO2 laser is as effective as Pulsed Dye laser for the treatment of Hypertrophic scars. J Dermatolog Treat. 2019 Nov 07;:1-17 Authors: Radmanesh M, Mehramiri S, Radmanesh R Abstract Background: Both pulsed dye laser(PDL) and Fractional CO2 laser(FCO2L) are used commonly for the treatment of hypertrophic scars.Objective: to compare the efficacy of PDL and FCO2L on hypertrophic scars.Patients and Method: One part of each scar,...
Fri Nov 08, 2019 15:04
Related ArticlesA Systematic Review of Cognitive and Behavioral Treatments for Individuals with Psoriasis. J Dermatolog Treat. 2019 Nov 07;:1-26 Authors: Sijercic I, Ennis N, Monson CM Abstract Background: Although there are effective dermatological treatments for psoriasis, a proportion of individuals also experience psychological distress not addressed by these treatments. Psychological factors may be targeted by cognitive behavioral therapy (CBT)...
Fri Nov 08, 2019 15:04
Related ArticlesAssociation between infliximab concentrations and clinical response in psoriasis: a prospective cohort study. J Dermatolog Treat. 2019 Nov 07;:1-27 Authors: Colls-Gonzalez M, Notario-Rosa J, Bas-Minguet J, Padullés-Zamora A, Morandeira-Rego F, Valentí-Medina F, Colom-Codina H, Padullés-Zamora N Abstract BACKGROUND: Infliximab (IFX) trough concentrations (Cmin) have been linked to treatment efficacy in psoriatic patients. Inter-individual...
Fri Nov 08, 2019 15:04
Related ArticlesMohs Surgery for the treatment of Lentigo Maligna and Lentigo Maligna Melanoma - A Systematic Review. J Dermatolog Treat. 2019 Nov 07;:1-23 Authors: Sharma AN, Foulad DP, Doan L, Lee PK, A Mesinkovska N Abstract BACKGROUND: The role of Mohs micrographic surgery (MMS) in the treatment of lentigo maligna (LM) and lentigo maligna melanoma (LMM) has been controversial. The use of frozen sections is commonly cited as a suboptimal way to distinguish...
Fri Nov 08, 2019 15:04
Related ArticlesIxekizumab Treatment Patterns and Healthcare Utilization and Costs for Patients with Psoriasis. J Dermatolog Treat. 2019 Nov 07;:1-26 Authors: Murage MJ, Gilligan AM, Tran O, Goldblum O, Burge R, Lin CY, Qureshi A Abstract Objectives: To describe ixekizumab treatment patterns, all-cause healthcare utilization, and costs among psoriasis patients.Methods: Adults diagnosed with psoriasis having ≥1 ixekizumab claim were selected from MarketScan®...
Fri Nov 08, 2019 15:04
Related ArticlesTranslational genomics of ovarian clear cell carcinoma. Semin Cancer Biol. 2019 Nov 04;: Authors: Khalique S, Lord CJ, Banerjee S, Natrajan R Abstract Ovarian clear cell carcinomas (OCCC) are rare aggressive, chemo-resistant tumours comprising approximately 13% of all epithelial ovarian cancers, which have distinct clinical and molecular features, when compared to other gynaecological malignancies. At present, there are no specific licensed...
Fri Nov 08, 2019 14:17
Related ArticlesA novel EWSR1-VGLL1 gene fusion in a soft tissue malignant myoepithelial tumor. Genes Chromosomes Cancer. 2019 Nov 07;: Authors: Komatsu M, Kawamoto T, Kanzawa M, Kawakami Y, Hara H, Akisue T, Kuroda R, Nakamura H, Hokka D, Jimbo N, Itoh T, Hirose T Abstract Soft tissue myoepithelial tumors are very rare mesenchymal tumors that are currently categorized as miscellaneous neoplasms with uncertain differentiation. Although the molecular...
Fri Nov 08, 2019 14:17
Related ArticlesImaging Manifestations of Acute and Chronic Renal Infection That Mimics Malignancy: How to Make the Diagnosis Using Computed Tomography and Magnetic Resonance Imaging. Can Assoc Radiol J. 2019 Nov;70(4):424-433 Authors: Udare A, Abreu-Gomez J, Krishna S, McInnes M, Siegelman E, Schieda N Abstract PURPOSE: To review the computed tomography and magnetic resonance imaging manifestations of acute and chronic renal infections that may mimic...
Fri Nov 08, 2019 13:07
Related ArticlesFinding a cure for tuberous sclerosis complex: From genetics through to targeted drug therapies. Adv Genet. 2019;103:91-118 Authors: McEneaney LJ, Tee AR Abstract Tuberous sclerosis complex (TSC) is a rare, autosomal dominant genetic condition caused by a mutation in either the TSC1 or TSC2 gene. Phenotypically, this leads to aberrant cell growth and the formation of benign tumors called hamartomas in multiple organs. Understanding the...
Fri Nov 08, 2019 13:07
Related ArticlesDisseminated "Haemophilus quentini" infection in a patient with multiple myeloma - a case report and review of the literature. Diagn Microbiol Infect Dis. 2019 Jul;94(3):293-296 Authors: Cohen R, Finn T, Babushkin F, Karalnik S, Paikin S, Adler A, Geffen Y, Rokney A, Ron M Abstract We describe a case report of a 56-year-old male with undiagnosed multiple myeloma who had severe sepsis associated with pneumonia, meningitis, polyarthritis,...
Fri Nov 08, 2019 13:07
Related ArticlesGlycemic control and complications in glycogen storage disease type I: Results from the Swiss registry. Mol Genet Metab. 2019 04;126(4):355-361 Authors: Kaiser N, Gautschi M, Bosanska L, Meienberg F, Baumgartner MR, Spinas GA, Hochuli M Abstract BACKGROUND: Regular carbohydrate intake to avoid hypoglycemia is the mainstay of dietary treatment in glycogen storage disease type I (GSDI). The aim of this study was to evaluate the quality...
Fri Nov 08, 2019 13:07
Related ArticlesElucidating the role of Agl in bladder carcinogenesis by generation and characterization of genetically engineered mice. Carcinogenesis. 2019 03 12;40(1):194-201 Authors: Sottnik JL, Mallaredy V, Chauca-Diaz A, Ritterson Lew C, Owens C, Dancik GM, Pagliarani S, Lucchiari S, Moggio M, Ripolone M, Comi GP, Frierson HF, Clouthier D, Theodorescu D Abstract Amylo-α-1,6-glucosidase,4-α-glucanotransferase (AGL) is an enzyme primarily responsible...
Fri Nov 08, 2019 13:07
Related ArticlesRadiological characteristics and predisposing factors of venous tumor thrombus in pelvic osteosarcoma: A mono-institutional retrospective study of 115 cases. Cancer Med. 2018 10;7(10):4903-4913 Authors: Liang H, Guo W, Yang R, Tang X, Yan T, Ji T, Yang Y, Li D, Xie L, Xu J Abstract BACKGROUND: Venous tumor thrombus (VTT) in pelvic osteosarcoma has been regarded as a rare oncological condition and few literatures investigated this issue....
Fri Nov 08, 2019 13:07
Related ArticlesSequential Imaging in Patient With Suspected Menière's Disease Identifies Endolymphatic Sac Tumor. Otol Neurotol. 2018 10;39(9):e856-e859 Authors: Kirsh ER, Kozin ED, Knoll RM, Wong K, Faquin W, Reinshagen KL, Kieff D, Rauch SD, Jung DH Abstract OBJECTIVE: The standard evaluation of patients with suspected Menière's disease (MD) includes initial imaging to rule out tumors of the temporal bone. Few guidelines, however, advocate sequential...
Fri Nov 08, 2019 13:07
Related ArticlesFalse-Positive Plasma Genotyping Due to Clonal Hematopoiesis. Clin Cancer Res. 2018 09 15;24(18):4437-4443 Authors: Hu Y, Ulrich BC, Supplee J, Kuang Y, Lizotte PH, Feeney NB, Guibert NM, Awad MM, Wong KK, Jänne PA, Paweletz CP, Oxnard GR Abstract Purpose: Plasma cell-free DNA (cfDNA) genotyping is increasingly used in cancer care, but assay accuracy has been debated. Because most cfDNA is derived from peripheral blood cells (PBC), we...
Fri Nov 08, 2019 13:07
Related Articles[Primary central nervous system lymphoma: pathogenesis and histomorphology]. Magy Onkol. 2017 Mar 08;61(1):81-87 Authors: Méhes G Abstract Lymphoproliferative diseases of the central nervous system are rare, diagnostics and treatment are accordingly challenging. Since the introduction of the 2008 WHO lymphoma classification, primary CNS DLBCL - also covering the associated primary ocular (vitreoretinal) lymphoma - is a separate entity....
Fri Nov 08, 2019 13:07
Related Articles[How can we treat Waldenström's macroglobulinemia?] Magy Onkol. 2017 03 08;61(1):12-20 Authors: Mucsi AO, Nagy Z Abstract Waldenström's macroglobulinemia is a rare, low-grade non-Hodgkin lymphoma of B cell origin, most common in elderly male patients with a median age of 64 years at diagnosis. It accounts for approximately 2% of hematologic malignancies. The disease is incurable now with a median overall survival of 6.2 years. In the...
Fri Nov 08, 2019 13:07
[The pathology and genetic background of lymphoplasmacytic lymphoma/Waldenström macroglobulinaemia].
Related Articles[The pathology and genetic background of lymphoplasmacytic lymphoma/Waldenström macroglobulinaemia]. Magy Onkol. 2017 Mar 08;61(1):6-11 Authors: Timár B Abstract Lymphoplasmacytic lymphoma is a rare low-grade B-cell lymphoma, which is composed of a mixture of small lymphocytes, plasmacytoid cells and plasma cells that typically infiltrate the bone marrow, but lymph nodes and rarely other organs can be involved as well. Waldenström macroglobulinaemia...
Fri Nov 08, 2019 13:07
Related ArticlesEstimation of cerebral blood flow velocity during breath-hold challenge using artificial neural networks. Comput Biol Med. 2019 Oct 17;115:103508 Authors: Al-Abed MA, Al-Bashir AK, Al-Rawashdeh A, Alex RM, Zhang R, Watenpaugh DE, Behbehani K Abstract The effect of untreated Obstructive Sleep Apnoea (OSA) on cerebral haemodynamics and CA impairment is an active field of research interest. A breath-hold challenge is usually used in clinical...
Fri Nov 08, 2019 14:36
Related ArticlesAssociation of obstructive sleep apnea and cerebral small vessel disease: a systematic review and meta-analysis. Sleep. 2019 Nov 07;: Authors: Huang Y, Yang C, Yuan R, Liu M, Hao Z Abstract STUDY OBJECTIVES: The objective of the present study was to investigate the association between obstructive sleep apnea (OSA) and the presence of various neuroimaging marker of cerebral small vessel disease (CSVD). METHODS: We systematically...
Fri Nov 08, 2019 14:36
Related ArticlesRisk of obstructive sleep apnea among senegalese dialysis patients. Saudi J Kidney Dis Transpl. 2019 Sep-Oct;30(5):1097-1102 Authors: Seck SM, Moussa Tondi ZM, Niang S, Ould Lemraboot AT, Ka EF Abstract Obstructive sleep apnea syndrome (OSAS) is a common condition in patients undergoing chronic dialysis and is associated with increased cardiovascular morbidity and mortality. This study aimed to determine the prevalence and risk factors...
Fri Nov 08, 2019 14:36
Related ArticlesA randomized controlled trial on ambulatory blood pressure lowering effect of CPAP in patients with obstructive sleep apnea and nocturnal hypertension. Blood Press. 2019 Nov 07;:1-10 Authors: Chen Q, Cheng YB, Shen M, Yin B, Yi HH, Feng J, Li M, Li QY, Li Y, Wang JG Abstract Objective: In a randomised controlled trial, we investigated the blood pressure (BP) lowering effect of continuous positive airway pressure (CPAP) in patients with...
Fri Nov 08, 2019 14:36
Related ArticlesPatient-Ventilator Asynchronies during Polysomnography. Ann Am Thorac Soc. 2018 10;15(10):1229-1233 Authors: Alter A, Mireles-Cabodevila E, Aboussouan LS PMID: 30272502 [PubMed - indexed for MEDLINE]
Fri Nov 08, 2019 13:04
Related ArticlesContinuous Positive Airway Pressure Titration: A Minor Change Can Make a Major Difference. Ann Am Thorac Soc. 2018 09;15(9):1105-1107 Authors: Gu C, Jun JC PMID: 30168748 [PubMed - indexed for MEDLINE]
Fri Nov 08, 2019 13:04
Related ArticlesInvited Commentary on "Postoperative outcomes in elderly patients undergoing pancreatic resection for pancreatic adenocarcinoma: A systematic review and meta-analysis". Int J Surg. 2019 Sep 30. pii: S1743-9191(19)30262-6. https://doi.org/10.1016/j.ijsu.2019.09.030. [Epub ahead of print]. Int J Surg. 2019 Nov 04;: Authors: Baram A PMID: 31698092 [PubMed - as supplied by publisher]
Fri Nov 08, 2019 15:02
Related ArticlesAn Invited Commentary on "Postoperative outcomes in elderly patients undergoing pancreatic resection for pancreatic adenocarcinoma: A systematic review and meta-analysis" (Int J Surg 2019 Sep 30. pii: S1743-9191(19)30262-6. https://doi.org/10.1016/j.ijsu.2019.09.030. [Epub ahead of print]). Int J Surg. 2019 Nov 04;: Authors: Moaven O PMID: 31698091 [PubMed - as supplied by publisher]
Fri Nov 08, 2019 15:02
Publication date: January 2020Source: Biomedicine & Pharmacotherapy, Volume 121Author(s): Yan Meng, Mengyuan Tian, Shuhua Yin, Songqing Lai, Ying Zhou, Junye Chen, Ming He, Zhangping LiaoAbstractTranslocator protein (TSPO) is highly expressed in the cardiovascular system, exerting crucial effects on both myocardial damage and protection. However, the role and mechanism of TSPO in myocardial ischemia/reperfusion (I/R) injury remains elusive. In the current study, we subjected H9c2 cardiomyocytes...
Fri Nov 08, 2019 12:59
Publication date: January 2020Source: Biomedicine & Pharmacotherapy, Volume 121Author(s): Yun Zhan, Rui Li, Chenlin Feng, Xiaolin Li, Shuai Huang, Lulu Wang, Zhihua Liu, Jiandong Jiang, Yanxing HanAbstractEsophageal squamous cell carcinoma (ESCC) is one of the most common cancers in China, accompanied by an extremely high mortality rate. Chlorogenic acid (CGA) is a small-molecule compound, that has been shown to have a wide range of biological activities, including antitumor. However, the efficacy...
Fri Nov 08, 2019 12:59
Publication date: January 2020Source: Biomedicine & Pharmacotherapy, Volume 121Author(s): Mahboubeh Tajaldini, Firooz Samadi, Ayyoob Khosravi, Azim Ghasemnejad, Jahanbakhsh AsadiAbstractBackgroundchemotherapy drugs are the common therapy for cancer cells with side effects. Recent studies reported that natural products may contribute to decreasing the side effects of chemotherapy drugs. Here, we aimed to investigate the effects of orange peel extract (OPE) and its main compound; naringin (NR)...
Fri Nov 08, 2019 12:59
Publication date: January 2020Source: Biomedicine & Pharmacotherapy, Volume 121Author(s): Zhe Liu, Xianmin Ge, Yuchen Gu, Yingying Huang, Hao Liu, Meiling Yu, Yamin LiuAbstractSignal transducer and activator of transcription 3 (STAT3) protein frequently overexpressed in many malignancies and plays an essential role in regulating proliferation, apoptosis, migration and invasion in cancer cells. However, No STAT3 inhibitor was used clinically. In this study, we evaluated the toxic potential of...
Fri Nov 08, 2019 12:59
Publication date: January 2020Source: Biomedicine & Pharmacotherapy, Volume 121Author(s): Wei-jun Huang, Wei-jing Liu, Yong-hua Xiao, Hui-juan Zheng, Yao Xiao, Qi Jia, Han-xue Jiang, Ze-bing Zhu, Chen-hui Xia, Xue-ting Han, Rui-xi Sun, He Nan, Zheng-dong Feng, Shi-dong Wang, Jin-xi ZhaoAbstractDiabetic nephropathy (DN) is a common but intractable diabetic microvascular complication. Tripterygium, a Chinses herb, has been proven to be effective for DN treatment. In this review, the efficacy and...
Fri Nov 08, 2019 12:59
Publication date: January 2020Source: Biomedicine & Pharmacotherapy, Volume 121Author(s): Ruheng Hua, Jiawei Yu, Xiyue Yan, Qingfeng Ni, Xiaofei Zhi, Xiaolong Li, Bin Jiang, Jianwei ZhuAbstractPurposeIn this study, we aimed to elucidate the biological roles of Syndecan-2 (SDC2) in colorectal cancer (CRC), thereby further understanding its clinical role.MethodsThe expression of SDC2 was assessed by qRT-PCR and Western blot analysis. To understand the potential biological role of SDC2, we also...
Fri Nov 08, 2019 12:59
Publication date: Available online 7 November 2019Source: Journal of VoiceAuthor(s): Geun-Hyo Kim, Ben Barsties von Latoszek, Yeon-Woo LeeSummaryObjectivesThis study aimed to verify the Acoustic Voice Quality Index (AVQI) version 3.01 and the Acoustic Breathiness Index (ABI) as tools for acoustic analyses in the Korean language.MethodsConcatenated voice samples of sustained vowels (SV) and continuous speech (CS) were collected from 151 subjects with dysphonia and 71 vocally healthy subjects. The...
Fri Nov 08, 2019 12:58
Publication date: Available online 7 November 2019Source: Journal of VoiceAuthor(s): Nico P. Paolillo, Luca Carrozza, Maurizio Osio, Elisabetta Rosa, Matteo ScalabrinSummaryObjectiveInspiratory Vocal Fry (IVF) is the voice production during inspiration of a sound with vocal fry perceptual characteristics. The existing scientific literature shows a lack of studies on it. The aim of the study is to highlight anatomical and physiological characteristics of IVF, to assess its effects on spoken and singing...
Fri Nov 08, 2019 12:58
Publication date: Available online 7 November 2019Source: Acta HistochemicaAuthor(s): Jirasuda Nakeim, Napamanee Kornthong, Jirawat Saetan, Supawadee Duangprom, Prasert Sobhon, Prapee SretarugsaAbstractSerotonin (5-HT) plays pivotal roles in many physiological processes including reproduction of crustaceans, which are mediated 5-HT receptors. The distributions of 5-HT and its receptor have never been explored in Portunus pelagicus. To validate the targets which indirectly indicate the roles of 5-HT...
Fri Nov 08, 2019 12:40
Abstract Purpose The aim of this study was to evaluate the influence of cyclobenzaprine and dexamethasone on the electrical activity of the masticatory muscles in patients who had undergone lower third molar surgery. Methods Thirty bilateral impacted lower third molars with indication of extraction were randomised into three groups: the control...
Fri Nov 08, 2019 12:40
Abstract Introduction Intraoperative mobile Cone-Beam Computed Tomography (CBCT) trends to develop for the management of complex facial fractures. It allows a real-time imaging and surgical navigation. Aim Through the presentation of two clinical cases, we aimed at presenting the procedure of intra-operative CBCT and new applications in maxillofacial...
Fri Nov 08, 2019 12:40
Abstract Diglycosidases hydrolyze the heterosidic linkage of diglycoconjugates, releasing the disaccharide and the aglycone. Usually, these enzymes do not hydrolyze or present only low activities towards monoglycosylated compounds. The flavonoid degrading fungus Acremonium sp. DSM 24697 produced two diglycosidases, which were termed 6-O-α-rhamnosyl-β-glucosidase I and II (αRβG I and II) because of their function of releasing the disaccharide rutinose (6-O-α-L-rhamnosyl-β-D-glucose)...
Fri Nov 08, 2019 02:00
Abstract Differentiating carotid near-occlusion (tight atherosclerotic stenosis causing distal artery size reduction) from conventional stenosis is the first step when grading carotid stenoses with NASCET method. The internal carotid artery (ICA) can be asymmetrically associated with Circle of Willis variations. When such ICA asymmetry coincides with stenosis, it may mimic near-occlusion. We studied ICA anatomical variant prevalence in 4042 consecutive CTA exams from all indications,...
Fri Nov 08, 2019 02:00
Background Physiotherapy of carpal tunnel syndrome (CTS) involves manual therapy based on neurodynamic techniques. Until now, two randomized controlled trials have shown that immediately after therapy, CTS patients who received neurodynamic techniques had significant improvement in nerve conduction, pain, symptom severity (SSS), functional state (FSS), muscle strength (MS) and two-point discrimination (2PD). However, long-term effects seem to be more important, as they are the only...
Fri Nov 08, 2019 02:00
Small sea urchins Strongylocentrotus intermedius (1–2 cm of test diameter) are exposed to different environments of light intensities after being reseeded to the sea bottom. With little information available about the behavioral responses of S. intermedius to different light intensities in the environment, we carried out an investigation on how S. intermedius is affected by three light intensity environments in terms of phototaxis, foraging and righting behaviors. They were no light (zero lx), low...
Fri Nov 08, 2019 02:00
Background The risk-taking behavior is largely modulated by the subject’s history, its lifestyles, by the characteristics of the situations with which it is compared, and also by the effects of prenatal androgens. Thus, the personality of the single person is a significant predictor of such way of acting. Methods The present study aimed to explore the relationship between Digit Ratio Measurement (2D:4D) and personality...
Fri Nov 08, 2019 02:00
Predatory dinosaurs were an important ecological component of terrestrial Mesozoic ecosystems. Though theropod dinosaurs carried this role during the Jurassic and Cretaceous Periods (and probably the post-Carnian portion of the Triassic), it is difficult to depict the Carnian scenario, due to the scarcity of fossils. Until now, knowledge on the earliest predatory dinosaurs mostly relies on herrerasaurids recorded in Carnian strata of South America. Phylogenetic investigations recovered the clade...
Fri Nov 08, 2019 02:00
Abstract This study identifies one possible mechanism whereby gene flow is interrupted in populations undergoing evolutionary divergence in sympatry; this is an important issue in evolutionary biology that remains poorly understood. Variation in trophic morphology was induced in three-spined stickleback by exposing them from an early age either to large benthic or to small pelagic prey. At sexual maturity, females given a choice between two breeding males, showed positive assortative...
Fri Nov 08, 2019 02:00
Thu Nov 07, 2019 21:58
Journal of International Medical Research, Ahead of Print.
Fri Nov 08, 2019 06:38
Distance measurements in the F 0 F 1 -ATP synthase from E. coli using smFRET and PELDOR spectroscopy
Abstract Fluorescence resonance energy transfer in single enzyme molecules (smFRET, single-molecule measurement) allows the measurement of multicomponent distance distributions in complex biomolecules similar to pulsed electron–electron double resonance (PELDOR, ensemble measurement). Both methods use reporter groups: FRET exploits the distance dependence of the electric interaction between electronic transition dipole moments of the attached fluorophores, whereas PELDOR spectroscopy...
Fri Nov 08, 2019 02:00
Journal of Cutaneous Medicine and Surgery, Ahead of Print. BackgroundThe literature contains conflicting reports on the epidemiology and frequency of hidradenitis suppurativa (HS), a chronic, recurrent inflammatory disease of the apocrine glands.ObjectiveTo evaluate the clinical and demographic characteristics of HS cases in Turkey and investigate the similarities with world epidemiology.MethodThe records of 208 patients that presented to our polyclinics and were diagnosed with HS between June 2012...
Fri Nov 08, 2019 08:12
Abstract Objectives The aim of the present study was to establish a rodent peri‐implantitis model induced by a mixed bacterial infection characterized by bone loss and semi‐quantitative graduation of peri‐implant inflammation in histological sections. Materials and Methods Two titanium implants were implanted in Spraque‐Dawley rats, bilaterally in each maxilla. After 3 weeks healing the rats were randomized into 3 groups according to different treatments over the next 3 months: Antibiotic‐Group...
Thu Nov 07, 2019 20:40
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