Related ArticlesPotential of robotic systems in phonosurgery. Robot Surg. 2019;6:3-8 Authors: Vasan N, Sharum M, Rodney JP Abstract There has been rapid growth in the utilization of robotic surgery in the head and neck. Its utilization in the phonosurgical space has lagged owing to difficulty with access and exposure to the laryngeal site, small working space due to the size of the larynx and the need to work around an endotracheal tube. The goal of...
Related ArticlesDetermining correct tracheal tube insertion depth by measuring distance between endotracheal tube cuff and vocal cords by ultrasound in Chinese adults: a prospective case-control study. BMJ Open. 2018 12 06;8(12):e023374 Authors: Chen X, Zhai W, Yu Z, Geng J, Li M Abstract OBJECTIVES: Unrecognised malposition of the endotracheal tube can lead to severe complications in patients under general anaesthesia. The purpose of this study was...
Related ArticlesA humanized mouse model to study asthmatic airway inflammation via the human IL-33/IL-13 axis. JCI Insight. 2018 11 02;3(21): Authors: Ito R, Maruoka S, Soda K, Katano I, Kawai K, Yagoto M, Hanazawa A, Takahashi T, Ogura T, Goto M, Takahashi R, Toyoshima S, Okayama Y, Izuhara K, Gon Y, Hashimoto S, Ito M, Nunomura S Abstract Asthma is one of the most common immunological diseases and is characterized by airway hyperresponsiveness (AHR),...
Related ArticlesStatPearls Book. 2019 01 Authors: Abstract The laryngopharynx, also referred to as the hypopharynx, is the most caudal portion of the pharynx and is a crucial connection point through which food, water, and air pass. Specifically, it refers to the point at which the pharynx divides anteriorly into the larynx and posteriorly into the esophagus. The act of swallowing, or deglutination, is a complex multistep process performed by several essential structures...
Related ArticlesStatPearls Book. 2019 01 Authors: Abstract Otalgia (ear pain) divides into two broad categories: primary and secondary otalgia. Primary otalgia is ear pain that arises directly from pathology within the inner, middle, or external ear. Secondary or referred otalgia is ear pain that occurs from pathology located outside the ear. A complex neural network innervates the ear as a result of complex embryologic development. The ear shares this neural network...
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Related ArticlesCase 272: Decubital Ischemic Fasciitis. Radiology. 2019 Dec;293(3):721-724 Authors: Kuyumcu G, Zhang Y, Ilaslan H Abstract HistoryA 92-year-old bedridden woman presented to the emergency department from an assisted living facility with fever, cough, and swelling over the right lateral hip. She had baseline dementia and frailty and had been bedridden for 4 years. She did not have any recent falls or history of trauma at the site of swelling....
Related ArticlesCase 276. Radiology. 2019 Dec;293(3):718-720 Authors: Delhaye C, Walsdorff M, Hackx M Abstract HistoryA 34-year-old man presented to the emergency department of our hospital for progressive shortness of breath and worsening productive cough of 2 weeks duration. He reported a 10-kg weight loss over 4 months but denied experiencing fever, chills, night sweats, or gastrointestinal, musculoskeletal, or neurologic symptoms. His medical history...
Related ArticlesThe SRU Consensus Statement on Simple Adnexal Cysts: Updated Guidelines for the Practitioner. Radiology. 2019 Dec;293(3):726 Authors: Grant EG PMID: 31751190 [PubMed - in process]
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Related ArticlesUse of 13-Valent Pneumococcal Conjugate Vaccine and 23-Valent Pneumococcal Polysaccharide Vaccine Among Adults Aged ≥65 Years: Updated Recommendations of the Advisory Committee on Immunization Practices. MMWR Morb Mortal Wkly Rep. 2019 Nov 22;68(46):1069-1075 Authors: Matanock A, Lee G, Gierke R, Kobayashi M, Leidner A, Pilishvili T Abstract Two pneumococcal vaccines are currently licensed for use in adults in the United States: a 13-valent...
Related ArticlesRadial Forearm Free Tissue Transfer to Clival Defect. J Neurol Surg B Skull Base. 2019 Dec;80(Suppl 4):S380-S381 Authors: Moy JD, Gardner PA, Sridharan S, Wang EW Abstract Introduction Reconstruction of craniocervical junction (CCJ) defects after endoscopic endonasal skull base surgery (ESBS) remains challenging, despite advancements in vascularized intranasal and regional flaps. Microvascular free tissue transfers have revolutionized...
Related ArticlesHeadache, Cerebrospinal Fluid Leaks, and Pseudomeningoceles after Resection of Vestibular Schwannomas: Efficacy of Venous Sinus Stenting Suggests Cranial Venous Outflow Compromise as a Unifying Pathophysiological Mechanism. J Neurol Surg B Skull Base. 2019 Dec;80(6):640-647 Authors: Higgins JN, Macfarlane R, Axon PR, Mannion RA, Tysome JR, Donnelly N, Moffat DA, Pickard JD Abstract Background Regardless of the operative approach, headache,...
Related ArticlesCSF Rhinorrhea Following Medical Treatment for Prolactinoma: Management and Challenges. J Neurol Surg B Skull Base. 2019 Dec;80(6):620-625 Authors: Arimappamagan A, Sadashiva N, Kandregula S, Shukla D, Somanna S Abstract Objective Cerebrospinal fluid (CSF) rhinorrhea following medical management of prolactinoma is a rare complication. We evaluated the clinical background of this condition, identify potential risk factors, and discuss...
Related ArticlesHospital Charge Variability across New York State: Sociodemographic Factors in Pituitary Surgery. J Neurol Surg B Skull Base. 2019 Dec;80(6):612-619 Authors: Kidwai SM, Yang A, Gray ML, McKee S, Iloreta AM, Shrivastava R, Govindaraj S Abstract Introduction Significant charge disparities exist across New York State (NYS). Race and income are associated with increased charges. To determine risk factor, we correlate hospital charges for...
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Related ArticlesNon-pharmacological Approach in the Management of Funcioanl Dyspepsia. J Neurogastroenterol Motil. 2019 Nov 22;: Authors: Wang YP, Herndon CC, Lu CL Abstract Functional dyspepsia (FD) is a common functional gastrointestinal disease which bears asignificant burden on society and individuals. Despite the high prevalence of FD, itspathophysiology remains poorly understood and the treatment options are limited andunsatisfactory. In the absence...
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Related ArticlesThe Use of Imaging to Detect Intracranial Tumors in Idiopathic Olfactory Dysfunction: A Systematic Review. Am J Rhinol Allergy. 2019 Nov 20;:1945892419889325 Authors: Birkenbeuel JL, Cheung DC, Sahyouni R, Goshtasbi K, Chua JT, Choy JAI, Bitner B, Kuan EC PMID: 31747774 [PubMed - as supplied by publisher]
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Sepsis is a severe condition associated with intestinal barrier failure, bacterial translocation, and intestinal inflammation. Administration of intestinal alkaline phosphatase partially restored this impaired gastrointestinal barrier in a murine model for sepsis, while influencing several tight junction proteins and cytokines. Abstract Background Sepsis is a severe pathological condition associated with systemic inflammation, intestinal inflammation, and gastrointestinal barrier dysfunction....
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Related ArticlesSerum Metabolome of Coffee Consumption and its Association with Bone Mineral Density: The Hong Kong Osteoporosis Study. J Clin Endocrinol Metab. 2019 Nov 21;: Authors: Chau YP, Au PCM, Li GHY, Sing CW, Cheng VKF, Tan KCB, Kung AWC, Cheung CL Abstract BACKGROUND: Inconsistent associations between coffee consumption and bone mineral density (BMD) have been observed in epidemiological studies. Moreover, the relationship of bioactive components...
Related ArticlesIn situ analysis reveals that CFTR is expressed in only a small minority of β-cells in normal adult human pancreas. J Clin Endocrinol Metab. 2019 Nov 21;: Authors: White MG, Maheshwari RR, Anderson SJ, Berlinguer-Palmini R, Jones C, Richardson SJ, Rotti PG, Armour SL, Ding Y, Krasnogor N, Engelhardt JF, Gray MA, Morgan NG, Shaw JAM Abstract CONTEXT: Although diabetes affects 40-50% of adults with cystic fibrosis, remarkably little is...
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Related ArticlesOffice-Based Steroid Injections for Idiopathic Subglottic Stenosis: Patient-Reported Outcomes, Effect on Stenosis, and Side Effects. Ann Otol Rhinol Laryngol. 2019 Nov 20;:3489419889066 Authors: Hoffman MR, Francis DO, Mai JP, Dailey SH Abstract OBJECTIVE: Office-based steroid injection has shown promise for idiopathic subglottic stenosis (iSGS). It is important to understand safety and patient-lived experience. We report patient experience...
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Related ArticlesRivaroxaban-Induced Acute Interstitial Nephritis: A Case Report. Am J Case Rep. 2019 Nov 21;20:1719-1722 Authors: Zafar F, Iqbal AM, Mubarik A, Rojas M, Muddassir S Abstract BACKGROUND Direct oral anticoagulant agents (DOACs) have become increasingly more popular in recent years and have largely replaced warfarin in the treatment of certain conditions, such as atrial fibrillation, and in the prevention of thromboembolic events. Rivaroxaban...
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Related ArticlesDifferent Pathological Complete Response Rates According to PAM50 Subtype in HER2+ Breast Cancer Patients Treated With Neoadjuvant Pertuzumab/Trastuzumab vs. Trastuzumab Plus Standard Chemotherapy: An Analysis of Real-World Data. Front Oncol. 2019;9:1178 Authors: Díaz-Redondo T, Lavado-Valenzuela R, Jimenez B, Pascual T, Gálvez F, Falcón A, Alamo MDC, Morales C, Amerigo M, Pascual J, Sanchez-Muñoz A, González-Guerrero M, Vicioso L, Laborda A, Ortega MV,...
Related ArticlesDistichiasis in association with entropion in metastatic HER2-positive breast cancer treated by pertuzumab, trastuzumab, and docetaxel combination chemotherapy. Breast J. 2019 Nov 20;: Authors: Tas F, Ozturker C Abstract We report the first case of distichiasis combined with entropion in a HER2-positive metastatic breast cancer patient treated by pertuzumab, trastuzumab, and docetaxel combination therapy. After 7 months, she had ocular...
Related ArticlesValidation of the AJCC prognostic stage for HER2-positive breast cancer in the ShortHER trial. BMC Med. 2019 Nov 21;17(1):207 Authors: Dieci MV, Bisagni G, Brandes AA, Frassoldati A, Cavanna L, Giotta F, Aieta M, Gebbia V, Musolino A, Garrone O, Donadio M, Rimanti A, Beano A, Zamagni C, Soto Parra H, Piacentini F, Danese S, Ferro A, Cagossi K, Sarti S, Gambaro AR, Romito S, Bazan V, Amaducci L, Moretti G, Foschini MP, Balduzzi S, Vicini R, D'Amico R, Griguolo...
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Related ArticlesTrajectory of ambulatory blood pressure after adenotonsillectomy in children with obstructive sleep apnea: comparison at three- and six-month follow-up. Sleep Med. 2019 Aug 14;65:127-133 Authors: Kang KT, Chiu SN, Lin CY, Weng WC, Lee PL, Hsu WC Abstract OBJECTIVE: Limited information is currently available on 24-h ambulatory blood pressure (ABP) changes after adenotonsillectomy (T&A) in children with obstructive sleep apnea (OSA)....
Related ArticlesUnattended sleep study in screening for sleep apnea in the acute phase of ischemic stroke. Sleep Med. 2019 Aug 08;65:121-126 Authors: Huhtakangas JK, Huhtakangas J, Bloigu R, Saaresranta T Abstract OBJECTIVES: We aimed to compare the feasibility of automatically and manually scored cardiorespiratory polygraphy results for sleep apnea screening in the acute phase of ischemic stroke. METHODS: Prospective study included 204 ischemic...
Related ArticlesReflex swallowing elicited by electrical stimulation in obstructive sleep apnea patients: a preliminary study. Respir Physiol Neurobiol. 2019 Nov 18;:103351 Authors: Mousa M, Sommer JU, Maurer JT Abstract This study tested whether electrical stimulation of the pharyngeal mucosa is able to induce reliably the swallowing reflex in awake and asleep obstructive sleep apnea (OSA) patients, and whether the induced reflexes affect the sleep...
Related ArticlesSignificance of sleep stability using cardiopulmonary coupling in sleep disordered breathing. Laryngoscope. 2019 Nov 21;: Authors: Seo MY, Hwang SJ, Nam KJ, Lee SH Abstract OBJECTIVES: The aim of this study was to assess the sleep quality and sleep stability according to the severity of obstructive sleep apnea (OSA) by using questionnaires and cardiopulmonary coupling (CPC) analysis. METHODS: Two hundred and twenty-one adults...
Related ArticlesMicrovascular Dysfunction in Heart Failure With Preserved Ejection Fraction. Front Physiol. 2019;10:1347 Authors: D'Amario D, Migliaro S, Borovac JA, Restivo A, Vergallo R, Galli M, Leone AM, Montone RA, Niccoli G, Aspromonte N, Crea F Abstract Heart failure with preserved ejection fraction (HFpEF) is an increasingly studied entity accounting for 50% of all diagnosed heart failure and that has claimed its own dignity being markedly different...
Related ArticlesSelective microstructural integrity impairments of the anterior corpus callosum are associated with cognitive deficits in obstructive sleep apnea. Brain Behav. 2019 Nov 20;:e01482 Authors: Zhang B, Zhu DM, Zhao W, Zhang Y, Yang Y, Zhang C, Zhu J, Yu Y Abstract BACKGROUND: There is some evidence that obstructive sleep apnea (OSA) patients have white matter integrity abnormality in the corpus callosum (CC). However, whether the CC subregions...
Related ArticlesExamining the Utility of a Novel Neurologic Test in Patients With Obstructive Sleep Apnea: A Pilot Study. J Prim Care Community Health. 2019 Jan-Dec;10:2150132719886951 Authors: Grover ML, Grover LL, Mookadam M, Mi L, Chang YH, Parish J Abstract Purpose: To test the association between participant King-Devick Test (KDT) times and obstructive sleep apnea (OSA) severity and evaluate for improvement after continuous positive airway pressure...
Related ArticlesContinuous positive airway pressure. Can Fam Physician. 2018 10;64(10):745 Authors: Yang PR, Korownyk C PMID: 30315020 [PubMed - indexed for MEDLINE]
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Related ArticlesOptogenetic stimulation of basal forebrain parvalbumin neurons modulates the cortical topography of auditory steady-state responses. Brain Struct Funct. 2019 May;224(4):1505-1518 Authors: Hwang E, Brown RE, Kocsis B, Kim T, McKenna JT, McNally JM, Han HB, Choi JH Abstract High-density electroencephalographic (hdEEG) recordings are widely used in human studies to determine spatio-temporal patterns of cortical electrical activity. How...
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Related ArticlesA Rare Case of Middle Ear Myxoma. Ear Nose Throat J. 2019 Nov 21;:145561319887273 Authors: Kelava I, Ajduk J, Ries M, Trotić R, Penezić A, Bedeković V PMID: 31749381 [PubMed - as supplied by publisher]
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Related ArticlesA Review on the Assessment of Radiation Induced Salivary Gland Damage After Radiotherapy. Front Oncol. 2019;9:1090 Authors: Wu VWC, Leung KY Abstract Head and neck cancers are common in Southern China including Hong Kong. Intensity modulated radiotherapy has been the treatment of choice for these patients. Although radiotherapy provides good local control, radiotherapy treatment side-effects are still inevitable due to close proximity...
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Publication date: Available online 21 November 2019Source: International ImmunopharmacologyAuthor(s): Yufu Ye, Wei Wang, Weichen Zhang, Yifan Peng, Yuanxing Liu, Songfeng Yu, Qi Chen, Lei Geng, Lin Zhou, Haiyang Xie, Mingchun Lai, Jun Yu, Shusen ZhengAbstractBackgroundHepatic ischemia reperfusion injury (IRI) is a primary cause of organ dysfunction occurring during liver resection surgery and transplantation. Galectin-1, an endogenous lectin expressed on lymphoid organs, plays an important role in...
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Related ArticlesCo-targeting p53-R249S and CDK4 synergistically suppresses survival of hepatocellular carcinoma cells. Cancer Biol Ther. 2019 Nov 21;:1-9 Authors: Wang H, Liao P, Zeng SX, Lu H Abstract p53-R249S (p53-RS) is frequently detected in human hepatocellular carcinoma (HCC) that is highly associated with hepatitis B infection and aflatoxin B1 exposure. Our previous study showed that CDK4/Cyclin D1 phosphorylates p53-RS at the cancer-derived...
Related ArticlesTRIM58 suppresses the tumor growth in gastric cancer by inactivation of β-catenin signaling via ubiquitination. Cancer Biol Ther. 2019 Nov 21;:1-10 Authors: Liu X, Long Z, Cai H, Yu S, Wu J Abstract Objective: To investigate and define the underlying molecular mechanism of tripartite motif-containing 58 (TRIM58) in regulating the tumor growth of gastric cancer (GC).Methods: TRIM58 expression in GC tissues and cells was detected by real-time...
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