Publication date: Available online 11 November 2019Source: Annals of Anatomy - Anatomischer AnzeigerAuthor(s): Robert Haładaj, Grzegorz Wysiadecki, R. Shane Tubbs, Mirosław TopolSummaryBackgroundThe levator palpebrae superioris muscle (LPS) acts as the upper eyelid's major elevator and retractor and is innervated by the oculomotor nerve. The muscle's paralysis is manifested by ptosis.Material and Methods70 orbits were dissected. After removing the orbital roof, the LPS’ shape and anatomical variations...
Tue Nov 12, 2019 18:55
Publication date: Available online 11 November 2019Source: Annals of Anatomy - Anatomischer AnzeigerAuthor(s): Shogo Hayashi, Hidetomo Hirouchi, Gen Murakami, Jőrg Wilting, Jose Francisco Rodríguez-Vázquez, Ji Jyun KimSummaryThe inferior pharyngeal constrictor (IPC) originates from the thyroid and cricoid cartilages and inserts to the pharyngeal raphe. In serial sagittal sections of 37 embryos and fetuses at 6-15 weeks (crown rump length 15-115 mm), we found 1) the IPC connecting to the sternothyroideus...
Tue Nov 12, 2019 18:55
Publication date: Available online 11 November 2019Source: Annals of Anatomy - Anatomischer AnzeigerAuthor(s): Christina Schmitt, Vivian Adamski, Florian Rasch, Rainer Adelung, Ralph Lucius, Michael Synowitz, Kirsten Hattermann, Janka Held-FeindtSummaryBackgroundThe treatment of glioblastomas (GBM) is still a clinical challenge. Current GBM therapeutic plans focus on the development of new strategies for local drug administration in the tumor cavity to realize an efficient long-term treatment with...
Tue Nov 12, 2019 18:55
Publication date: Available online 11 November 2019Source: Annals of Anatomy - Anatomischer AnzeigerAuthor(s): Agnieszka Przystańska, Artur Rewekant, Alicja Sroka, Tomasz Gedrange, Michał Ekkert, Katarzyna Jończyk-Potoczna, Agata Czajka-JakubowskaSummaryBackgroundIn the postnatal period, some sexual dimorphism is observed from the moment of birth, but it is most pronounced from puberty. The aim of the study based on CT images was to assess possible sexual dimorphism of the maxillary sinus in children...
Tue Nov 12, 2019 18:55
Publication date: Available online 11 November 2019Source: Artificial Intelligence in MedicineAuthor(s): Xianlun Tang, Ting Wang, Yiming Du, Yuyan DaiAbstractAs new human-computer interaction technology, brain-computer interface has been widely used in various fields of life. The study of EEG signals can not only improve people's awareness of the brain, but also establish new ways for the brain to communicate with the outside world. This paper takes the motion imaging EEG signal as the research object...
Tue Nov 12, 2019 17:30
Publication date: Available online 11 November 2019Source: Clinical BiochemistryAuthor(s): Li Liu, Michael R. Shurin, Sarah E. WheelerAbstractObjectivesMultiple myeloma (MM) is characterized by malignant growth of plasma cells, usually producing a monoclonal antibody (mAb). New treatments for MM include therapeutic monoclonal antibodies (tmAbs), but patients treated with tmAb demonstrate interference on serum electrophoresis (SPE) and immunoprecipitation electrophoresis (IEP). Evaluation of treatment...
Tue Nov 12, 2019 12:33
Publication date: Available online 11 November 2019Source: Clinical Psychology ReviewAuthor(s): Joseph K. Carpenter, Kristina Conroy, Angelina F. Gomez, Laura C. Curren, Stefan G. HofmannAbstractTrait mindfulness appears to be related to lower levels of negative affective symptoms, but it remains uncertain which facets of mindfulness are most important in this relationship. Accordingly, the present meta-analysis examined studies reporting correlations between affective symptoms and trait mindfulness...
Tue Nov 12, 2019 16:55
Publication date: November 2019Source: Clinical Psychology Review, Volume 73Author(s): Danique Smeijers, Erik B.H. Bulten, Inti A. BrazilAbstractOur behavior is partly a product of our perception of the world, and aggressive individuals have been found to have ‘hostility biases’ in their perception and interpretation of social information. Four types of hostility biases can be distinguished: the hostile attribution, interpretation, expectation, and perception bias. Such low-level biases are believed...
Tue Nov 12, 2019 16:55
Publication date: Available online 11 November 2019Source: European Annals of Otorhinolaryngology, Head and Neck DiseasesAuthor(s): A. Cakır Cetın, E.A. Gunerı
Tue Nov 12, 2019 17:48
Publication date: Available online 11 November 2019Source: European Annals of Otorhinolaryngology, Head and Neck DiseasesAuthor(s): E. Chabrillac, G. De Bonnecaze, M. Rives, V. Lubrano, E. Serrano, S. VergezAbstractIntroductionIn old and frail patients, oncologic anterior skull-base surgery through an endonasal endoscopic approach avoids the morbidity incurred by transfacial and transcranial approaches, sometimes considered unreasonable, although surgery remains the gold standard treatment for sinonasal...
Tue Nov 12, 2019 17:48
Publication date: Available online 11 November 2019Source: Experimental Cell ResearchAuthor(s): Xiaomi Li, Huimin Lu, Yanzheng Gu, Xueguang Zhang, Guangbo Zhang, Tongguo Shi, Weichang ChenAbstractGamma delta (γδ) T cell-based tumor immunotherapy has been one of the most promising cancer immunotherapeutic strategies. However, the key regulators of the Vγ9Vδ2 T cell-mediated antitumor response remain unclear. Recently, mounting reports have indicated that Tim-3 performs critical roles in the regulation...
Tue Nov 12, 2019 17:30
Publication date: Available online 12 November 2019Source: Food ControlAuthor(s): Bille Laura, Crovato Stefania, Manfrin Amedeo, Dalla Pozza Manuela, Toson Marica, Franzago Eleonora, Pinto Anna, Mascarello Giulia, Muzzolon Orietta, Tosi Federica, Negroni Gianluigi, Cappi Gualberto, Obregon Pablo, Ravarotto Licia, Binato GiovanniAbstractPurposeof the present study was to evaluate the total Hg (THg) level in Billfish caught in the Western Central Atlantic and to assess the potential health consequences...
Tue Nov 12, 2019 17:35
Publication date: Available online 12 November 2019Source: Food ControlAuthor(s): Seockmo Ku, Suyoung Yang, Hyun Ha Lee, Deokyeong Choe, Tony V. Johnston, Geun Eog Ji, Myeong Soo ParkAbstractIn this work, the previously identified Bifidobacterium strain, Bifidobacterium animalis subsp. lactis AD011 (obtained from an infant fecal sample), intended as a potential probiotic microorganism, is assessed for its safety using multiple in vitro virulence assays (ammonia and biogenic amine synthesis, hemolytic...
Tue Nov 12, 2019 17:35
Publication date: 19 November 2019Source: Journal of the American College of Cardiology, Volume 74, Issue 20Author(s): Martijn W. Smulders, Bas L.J.H. Kietselaer, Joachim E. Wildberger, Pieter C. Dagnelie, Hans-Peter Brunner–La Rocca, Alma M.A. Mingels, Yvonne J.M. van Cauteren, Ralph A.L.J. Theunissen, Mark J. Post, Simon Schalla, Sander M.J. van Kuijk, Marco Das, Raymond J. Kim, Harry J.G.M. Crijns, Sebastiaan C.A.M. BekkersAbstractBackgroundPatients with non–ST-segment elevation myocardial infarction...
Tue Nov 12, 2019 12:34
Publication date: 19 November 2019Source: Journal of the American College of Cardiology, Volume 74, Issue 20Author(s): Henry H. Ting, Pablo Moreno Franco
Tue Nov 12, 2019 12:34
Publication date: 19 November 2019Source: Journal of the American College of Cardiology, Volume 74, Issue 20Author(s): Nirav Patel, Anirudh Bhargava, Rajat Kalra, Vibhu Parcha, Garima Arora, Paul Muntner, Pankaj Arora
Tue Nov 12, 2019 12:34
Publication date: 19 November 2019Source: Journal of the American College of Cardiology, Volume 74, Issue 20Author(s): David Z. Cherney, Ayodele Odutayo, Ronnie Aronson, Justin Ezekowitz, John D. ParkerAbstractPoorly controlled type 2 diabetes mellitus is associated with the development of cardiovascular and renal complications, resulting in significant morbidity and mortality. Intensive glycemic control has been a major focus for clinical trials and novel drug development. However, narrow treatment...
Tue Nov 12, 2019 12:34
Publication date: 19 November 2019Source: Journal of the American College of Cardiology, Volume 74, Issue 20Author(s): Nathan D. WongCorresponding Author
Tue Nov 12, 2019 12:34
Publication date: 19 November 2019Source: Journal of the American College of Cardiology, Volume 74, Issue 20Author(s): Lisandro D. Colantonio, Erin D. Shannon, Kate K. Orroth, Rebecca Zaha, Elizabeth A. Jackson, Robert S. Rosenson, Jason Exter, Katherine E. Mues, Paul MuntnerAbstractBackgroundThe 2018 American Heart Association/American College of Cardiology (AHA/ACC) cholesterol guideline includes recommendations for intensive lipid-lowering therapy in patients at very high risk for atherosclerotic...
Tue Nov 12, 2019 12:34
Publication date: 19 November 2019Source: Journal of the American College of Cardiology, Volume 74, Issue 20Author(s): Jean-Louis Vanoverschelde, David VancraeynestCorresponding Author
Tue Nov 12, 2019 12:34
Publication date: 19 November 2019Source: Journal of the American College of Cardiology, Volume 74, Issue 20Author(s): Li-Tan Yang, Maurice Enriquez-Sarano, Hector I. Michelena, Vuyisile T. Nkomo, Christopher G. Scott, Kent R. Bailey, Didem Oguz, Muhammad Wajih Ullah, Patricia A. PellikkaAbstractBackgroundThe natural history of stage B aortic regurgitation (AR) is unknown.ObjectivesThis study sought to examine determinants, rate, and consequences of progression of AR.MethodsConsecutive patients with ≤moderate...
Tue Nov 12, 2019 12:34
Publication date: 19 November 2019Source: Journal of the American College of Cardiology, Volume 74, Issue 20Author(s): Admir Dedic, Murat Arslan, Joseph S. AlpertCorresponding Author
Tue Nov 12, 2019 12:34
Publication date: 19 November 2019Source: Journal of the American College of Cardiology, Volume 74, Issue 20Author(s): George A. Mensah, Gregory A. Roth, Valentin Fuster
Tue Nov 12, 2019 12:34
Publication date: 19 November 2019Source: Journal of the American College of Cardiology, Volume 74, Issue 20Author(s): Gregory G. Schwartz, Bernard R. ChaitmanCorresponding Author
Tue Nov 12, 2019 12:34
Publication date: 19 November 2019Source: Journal of the American College of Cardiology, Volume 74, Issue 20Author(s): Ron BlanksteinCorresponding Author
Tue Nov 12, 2019 12:34
Publication date: 19 November 2019Source: Journal of the American College of Cardiology, Volume 74, Issue 20Author(s): Giovanni Donato Aquaro, Yacob Ghebru Habtemicael, Giovanni Camastra, Lorenzo Monti, Santo Dellegrottaglie, Claudio Moro, Chiara Lanzillo, Alessandra Scatteia, Mauro Di Roma, Gianluca Pontone, Martina Perazzolo Marra, Andrea Barison, Gianluca Di Bella, “Cardiac Magnetic Resonance” Working Group of the Italian Society of CardiologyAbstractBackgroundCardiac magnetic resonance (CMR)...
Tue Nov 12, 2019 12:34
Publication date: 19 November 2019Source: Journal of the American College of Cardiology, Volume 74, Issue 20Author(s):
Tue Nov 12, 2019 12:34
Publication date: 19 November 2019Source: Journal of the American College of Cardiology, Volume 74, Issue 20Author(s):
Tue Nov 12, 2019 12:34
Publication date: 19 November 2019Source: Journal of the American College of Cardiology, Volume 74, Issue 20Author(s):
Tue Nov 12, 2019 12:34
Publication date: 19 November 2019Source: Journal of the American College of Cardiology, Volume 74, Issue 20Author(s): David E. Winchester
Tue Nov 12, 2019 12:34
Publication date: Available online 11 November 2019Source: Journal of the American College of CardiologyAuthor(s): Rodrigo Fernandez-Jimenez, Risa Jaslow, Sameer Bansilal, Raquel Diaz-Munoz, Monali Fatterpekar, Maribel Santana, Andrea Clarke-Littman, Jacqueline Latina, Ana V. Soto, Christopher A. Hill, Mohamed Al-Kazaz, Rajeev Samtani, Rajesh Vedanthan, Chiara Giannarelli, Jason C. Kovacic, Emilia Bagiella, Andrew Kasarskis, Zahi A. Fayad, Valentin FusterAbstractBackgroundThe current trends of unhealthy...
Tue Nov 12, 2019 12:34
Publication date: Available online 11 November 2019Source: Journal of the American College of CardiologyAuthor(s): Connie R. Bezzina, Roddy Walsh, Najim LahrouchiCorresponding Author
Tue Nov 12, 2019 12:34
Publication date: Available online 11 November 2019Source: Journal of the American College of CardiologyAuthor(s): Amit V. Khera, Heather Mason-Suares, Deanna Brockman, Minxian Wang, Martin J. VanDenburgh, Ozlem Senol-Cosar, Candace Patterson, Christopher Newton-Cheh, Seyedeh M. Zekavat, Julie Pester, Daniel I. Chasman, Christopher Kabrhel, Majken K. Jensen, JoAnn E. Manson, J. Michael Gaziano, Kent D. Taylor, Nona Sotoodehnia, Wendy S. Post, Stephen S. Rich, Jerome I. RotterAbstractBackgroundSudden...
Tue Nov 12, 2019 12:34
Publication date: Available online 11 November 2019Source: Journal of the American College of CardiologyAuthor(s): Muthiah Vaduganathan, Gregg C. Fonarow, Stephen J. Greene, Adam D. DeVore, Nancy M. Albert, Carol I. Duffy, C. Larry Hill, John A. Spertus, Laine E. Thomas, Javed Butler
Tue Nov 12, 2019 12:34
Publication date: Available online 11 November 2019Source: Journal of the American College of CardiologyAuthor(s): Janet W. Rich-EdwardsCorresponding Author
Tue Nov 12, 2019 12:34
Publication date: Available online 11 November 2019Source: Journal of the American College of CardiologyAuthor(s): Michael C. Honigberg, Seyedeh Maryam Zekavat, Krishna Aragam, Derek Klarin, Deepak L. Bhatt, Nandita S. Scott, Gina M. Peloso, Pradeep NatarajanAbstractBackgroundHistory of a hypertensive disorder of pregnancy (HDP) among women may be useful to refine atherosclerotic cardiovascular disease risk assessments. However, future risk of diverse cardiovascular conditions in asymptomatic middle-aged...
Tue Nov 12, 2019 12:34
Publication date: Available online 11 November 2019Source: Journal of the American College of CardiologyAuthor(s): Sean Murphy, Cian McCarthy, Joshua A. Cohen, Saad Rehman, Maeve Jones-O’Connor, David S. Olshan, Avinainder Singh, Muthiah Vaduganathan, Jinghan Cui, James L. Januzzi, Jason H. Wasfy
Tue Nov 12, 2019 12:34
Publication date: Available online 11 November 2019Source: Journal of the American College of CardiologyAuthor(s): Muthiah Vaduganathan, Brian L. Claggett, Akshay S. Desai, Stefan D. Anker, Sergio V. Perrone, Stefan Janssens, Davor Milicic, Juan L. Arango, Milton Packer, Victor C. Shi, Martin P. Lefkowitz, John J.V. McMurray, Scott D. SolomonAbstractBackgroundThe period shortly after hospitalization for heart failure (HF) represents a high-risk window for recurrent clinical events, including rehospitalization...
Tue Nov 12, 2019 12:34
Publication date: Available online 11 November 2019Source: Microbiological ResearchAuthor(s): Shu Chen, Gaofu Qi, Gaoqiang Ma, Xiuyun ZhaoAbstractLong-term continuous cropping has led to epidemic of bacterial wilt disease in Southern China. Bacterial wilt disease is caused by Ralstonia solanacearum and difficult to control. In order to control bacterial wilt, rice hull biochar was applied to soil with different doses (0, 7.5, 15, 30 and 45 t ha-1) in a field trial. After three years, the influence...
Tue Nov 12, 2019 17:53
Publication date: Available online 11 November 2019Source: New BiotechnologyAuthor(s): Bin Liu, Shuang Long, Jianghai LiuAbstractThe Kunkel method is a widely used site-directed mutagenesis strategy that introduces point mutations by annealing mutation-containing oligonucleotides to single-stranded uracil-containing DNA (dU-ssDNA) templates. The method is fast and inexpensive and has been routinely employed to generate point mutations and multi-site mutations. However, its efficiency for point mutations...
Tue Nov 12, 2019 17:47
Publication date: Available online 11 November 2019Source: Operative Techniques in Otolaryngology-Head and Neck SurgeryAuthor(s): Shivani Shah-BeckerMost benign tumors of the larynx are epithelial in origin, with nearly 85% being laryngeal papilloma. Nonepithelial laryngeal tumors are uncommon and more than 50% of these are malignant. Therefore, benign nonepithelial solid tumors of the larynx are quite rare. The management of these tumors varies based on the site of origin, specific pathology, tumor...
Tue Nov 12, 2019 12:17
Publication date: Available online 11 November 2019Source: Respiratory Physiology & NeurobiologyAuthor(s): Hongshu Sui, Mingjiu Luo, Yaya Miao, Wanjing Cheng, Shan Wen, Bohou Zhao, Yuming Li, Zengyun Qiao, Yaling Liu, Changlong XuAbstractObjectiveThe beneficial role of Cystic fibrosis transmembrane conductance regulator (CFTR) was reported in acute lung injury (ALI), however, there was no direct evidence supporting the relationship between CFTR and cell autophagy in ALI. Here, this study is to...
Tue Nov 12, 2019 17:08
Publication date: Available online 11 November 2019Source: Toxicology LettersAuthor(s): Guodong Lin, Yawei Sun, Jianhai Long, Xin Sui, Jun Yang, Qian Wang, Shuai Wang, Huanhuan He, Yuan Luo, Zewu Qiu, Yongan WangAbstractThallium ion (Tl+) and its neurotoxic products are widely known to cause severe neurological complications. However, the exact mechanism of action remains unknown, with limited therapeutic options available. This study aims to examine the toxic effects of Thallium (I) nitrate (TlNO3)...
Tue Nov 12, 2019 11:47
Authors: Oft M Abstract The expansion and activation of tumor antigen reactive CD8+ T cells are primary goals of immunotherapies for cancer. IL-10 is an anti-inflammatory cytokine with an essential role in the development and proliferation of regulatory T cells, restricting myeloid and chronic inflammatory T cell responses. However, IL-10 is also essential for the expansion of antigen activated, tumor specific CD8+ T cells, leading to spontaneous tumor development in IL-10 deficient patients...
Wed Nov 06, 2019 00:00
Authors: Geginat J PMID: 31706854 [PubMed - as supplied by publisher] (Source: Seminars in Immunology)
Wed Nov 06, 2019 00:00
Authors: Boonpiyathad T, Sözener ZC, Satitsuksanoa P, Akdis CA Abstract Asthma is a chronic airway disease, which affects more than 300 million people. The pathogenesis of asthma exhibits marked heterogeneity with many phenotypes defining visible characteristics and endotypes defining molecular mechanisms. With the evolution of novel biological therapies, patients, who do not-respond to conventional asthma therapy require novel biologic medications, such as anti-IgE, anti-IL-5 and anti-IL4/IL13...
Tue Nov 05, 2019 00:00
Disturbances in complement recognition and control in human disease - An editorial to a special issue on "Complement Regulation". Semin Immunol. 2019 Nov 05;:101345 Authors: Meri S PMID: 31703833 [PubMed - as supplied by publisher] (Source: Seminars in Immunology)
Tue Nov 05, 2019 00:00
Abstract Privacy is a psychological topic suffering from historical neglect—a neglect that is increasingly consequential in an era of social media connectedness, mass surveillance, and the permanence of our electronic footprint. Despite fundamental changes in the privacy landscape, social and personality psychology journals remain largely unrepresented in debates on the future of privacy. By contrast, in disciplines like computer science and media and communication studies, engaging directly with...
Tue Nov 12, 2019 12:44
Sprache Stimme GehörDOI: 10.1055/a-0949-7081© Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents | Full text
Tue Nov 12, 2019 01:00
Sprache Stimme GehörDOI: 10.1055/a-0949-6520The aim of the present study was a systematic literature review on selected evidence-based voice therapy programs for the treatment of various types of dysphonia. The results showed that nine of seventeen voice therapy programs complied the selection criteria. All nine voice therapy programs revealed significant improvements in various aspects of laryngeal evaluation, voice quality, vocal function, and/or self-evaluation. These improvements might be expected...
Tue Nov 12, 2019 01:00
Abstract Purpose We present a case of a bilateral reversed palmaris longus muscle and a systematic review of the literature on this anatomical variation. Methods Routine dissection of a 90-year-old male cadaver revealed a rare bilateral reversed palmaris longus. This was documented photographically, and length and relation to anatomical landmarks were recorded....
Tue Nov 12, 2019 02:00
Related ArticlesNon-thermal plasma treated solution with potential as a novel therapeutic agent for nasal mucosa regeneration. Sci Rep. 2018 09 13;8(1):13754 Authors: Won HR, Kang SU, Kim HJ, Jang JY, Shin YS, Kim CH Abstract Adequate and rapid mucosal regeneration is one of the most important factors in the healing process of nasal mucosa after surgery or trauma. In particular, delayed mucosal regeneration after surgery is an important cause of surgical...
Tue Nov 12, 2019 13:18
Related ArticlesRemote-access thyroid surgery-progress, assessment, and reflection. J Surg Oncol. 2018 09;118(3):388-389 Authors: Patel KN, Ganly I, Shaha AR PMID: 30176175 [PubMed - indexed for MEDLINE]
Tue Nov 12, 2019 13:18
Related ArticlesIn response to Double-blind, placebo-controlled study with alginate suspension for laryngopharyngeal reflux disease. Laryngoscope. 2018 10;128(10):E349-E350 Authors: Lechien JR, Karkos PD, Harmegnies B, Saussez S PMID: 29603239 [PubMed - indexed for MEDLINE]
Tue Nov 12, 2019 13:18
Colin Levey takes a look at a systematic review assessing the 10-year survival of titanium roughened surface, solid screw dental implants in adults. 4 RCTs and 14 prospective studies) were included traditional analysis and sensitivity analysis taking into account missing data was conducted providing a more conservative estimate of survival and a broader prediction interval. The post Dental Implant ‘drop out’ rates at 10 years – do they matter? appeared first on National Elf Service.
08:02
By LISE ALSCHULER, ND, FABNO I am a naturopathic doctor, and because I operate outside of insurance-based medicine, I have, what most healthcare providers would consider, lots of time with my patients. My typical first patient appointment is 90 minutes long and my follow-up visits are 30 minutes long. What, you may ask, do I do with all this time? I get to know my patients by listening to their stories, their concerns and their hopes. We delve into their health concerns, we...
Tue Nov 12, 2019 17:25
Upadacitinib 15 mg was efficacious and well tolerated in patients with active ankylosing spondylitis who had an inadequate response or contraindication to non-steroidal anti-inflammatory drugs. These data support the further investigation of upadacitinib for the treatment of axial spondyloarthritis.
Tue Nov 12, 2019 18:00
JAK and signal transducers and activators of the transcription signal transduction (known as STAT) pathway and upstream cytokine receptor signalling have a principal role in the pathogenesis of many inflammatory and autoimmune conditions, including inflammatory bowel disease, psoriasis, rheumatoid arthritis, spondyloarthritis, and systemic lupus erythematosus.1 There are four JAKs in humans, JAK1, JAK2, and JAK3, and TYK2. Several JAK inhibitors have been developed over the past decade targeting...
Tue Nov 12, 2019 18:00
Objectives To investigate the prognostic impact of primary tumor‐specific growth rate (TSGR) on treatment outcomes after definitive radiation therapy (RT) for nonoropharyngeal squamous cell carcinoma (non‐OPSCC). Methods The diagnostic tumor and nodal volumes of 39 non‐OPSCC patients were contoured and compared to corresponding RT planning scan volumes to determine TSGR. Overall survival (OS), disease‐free survival (DFS), and local recurrence‐free survival were evaluated according to the Kaplan‐Meier...
Tue Nov 12, 2019 17:13
Objective To determine the natural history of vocal fold cysts, by undertaking a retrospective analysis of data from a single clinical institute. Methods All patients diagnosed with vocal fold cysts were identified from January 2006 to June 2018. A total of 87 patients that elected not to have surgery or who had an interval of observation greater than 90 days prior to surgical intervention were further analyzed. The primary outcome was whether the cyst enlarged, reduced in size, resolved or...
Tue Nov 12, 2019 17:10
Objectives/Hypothesis Patients are frequently advised to sneeze with an open mouth and avoid nose‐blowing following an endoscopic endonasal approache (EEA) to the skull base, despite a lack of quantitative evidence. This study applies computational fluid dynamics (CFD) to quantify sinus pressures along the skull base during sneezing. Study Design Case–control series. Methods Computed tomography or magnetic resonance imaging scans of four post‐EEA patients and four healthy controls were...
Tue Nov 12, 2019 17:05
Objective To estimate the diagnostic performance of Narrow Band Imaging (NBI) in patients with cervical metastasis from head and neck squamous cell carcinoma of unknown primary (SCCUP) origin. Methods PubMed, Embase, and Scopus databases were systematically scrutinized up to July 1, 2019, looking for studies that encompassed the NBI in the SCCUP diagnostic work up. The main inclusion criteria for eligible articles for the meta‐analysis were non‐evidence of primary tumor after physical examination...
Tue Nov 12, 2019 17:00
Objective Compare intraoperative and postoperative outcomes of endoscopic and microscopic stapes surgery to provide objective evidence on whether the former is a better alternative than the latter. Methods We performed a systematic review and meta‐analysis for studies that compared endoscopic stapes surgery with microscopic stapes surgery. Only studies that met predetermined criteria were selected and assessed for bias and quality. Primary outcomes were postoperative air–bone gap (ABG) and...
Tue Nov 12, 2019 17:00
Tue Nov 12, 2019 16:56
Objectives/Hypothesis To assess the face, content, construct, and concurrent validity of the PHACON Sinonasal Surgery Simulator (SNSS). Study Design Prospective cohort study. Methods A total of 12 otolaryngology residents were recruited to perform sinonasal surgery on the simulator followed by cadaveric heads. Resident performances were recorded and de‐identified. Face and content validities were evaluated based on 5‐point Likert scale questionnaires. The recordings were evaluated by...
Tue Nov 12, 2019 16:55
Abstract We read with interest the recent retrospective study by Querido et al (1) investigating the incidence of Hepatitis B virus (HBV) reactivation in kidney transplant (KT) recipients with positive anti‐Hepatitis B core (HBcAb) and negative Hepatitis B surface antigen (HBsAg). This study found that 2 out of 70 KT patients with HBcAb positivity developed HBV reactivation with reemergence of HBs Ag and HBV DNA viremia. Only 15% of the patients received rituximab as part of induction therapy (1);...
Tue Nov 12, 2019 11:46
CONCLUSIONS: Tanzania's integrated EIR-eLMIS may increase vaccine availability compared to its paper and Excel based system. Post-introduction of an eLMIS, the odds of a vaccine stock-out reduced over time. Further research could determine the impact of this intervention on vaccine wastage and replenishment response times. PMID: 31706808 [PubMed - as supplied by publisher] (Source: Vaccine)
Thu Nov 07, 2019 00:00
CONCLUSIONS: Influenza vaccination coverage among Polish teachers is alarmingly low; vaccine receipt was associated with teacher attitudes and beliefs. Future interventions related to maximizing vaccination coverage in this group should take advantage of the involvement of family physicians and specifically focus on teachers who have never been vaccinated before. As knowledge about influenza positively influences vaccination decisions, education strategies should focus on reducing knowledge gaps...
Wed Nov 06, 2019 00:00
Summary of the Vaccines and Related Biological Products Advisory Committee meeting held to consider evaluation of vaccine candidates for the prevention of respiratory syncytial virus disease in RSV-naïve infants. Vaccine. 2019 Nov 06;: Authors: Browne SK, Beeler JA, Roberts JN Abstract Respiratory syncytial virus (RSV), is a common cause of serious acute lower respiratory tract illness in infants and young children, causing substantial morbidity and mortality globally. Treatment...
Wed Nov 06, 2019 00:00
Authors: Harmon SHE, Faour D, MacDonald NE, Graham J, Steffen C, Henaff L, Shendale S Abstract In 2017, the Strategic Advisory Group of Experts on Immunization's Assessment Report of the Global Vaccine Action Plan noted the need to "better document the ways in which legislation and regulations have been used to promote or undermine immunization at the national level". Despite National Immunization Technical Advisory Groups (NITAGs) now existing in over 134 countries worldwide, there has...
Wed Nov 06, 2019 00:00
In conclusion, administration of LetiFend® was able to reduce CIC elicited after experimental infection with L. infantum in a dog model in a process that may be related to complement system activation. PMID: 31706810 [PubMed - as supplied by publisher] (Source: Vaccine)
Wed Nov 06, 2019 00:00
Authors: Kim E, Won G, Lee JH Abstract Efforts to develop a safe, effective, and affordable dengue vaccine have focused on providing simultaneous immunity against all four serotypes of the dengue virus (DENV). In the current study, Salmonella Typhimurium (ST) lysed by gene E activation was genetically constructed to deliver the envelope protein domain III (EDIII) of all four serotypes of DENV using a foreign antigen delivery and expression vector, pJHL184. Each DENV-EDIII protein expressed...
Wed Nov 06, 2019 00:00
This study established surface shaving in B. pertussis, confirmed key expression differences and identified unknown surface proteins which may be potential vaccine antigens. PMID: 31703933 [PubMed - as supplied by publisher] (Source: Vaccine)
Tue Nov 05, 2019 00:00
CONCLUSION: Non-inferiority of IPV-Al to IPV with respect to seroconversion was confirmed and a robust booster response was demonstrated. Both vaccines had a similar safety profile. ClinicalTrials.gov identifier: NCT03032419. PMID: 31703934 [PubMed - as supplied by publisher] (Source: Vaccine)
Tue Nov 05, 2019 00:00
Authors: Mottram L, Lundgren A, Svennerholm AM, Leach S Abstract Antibody avidity is an important measure of the quality of vaccine-induced immune responses. Murine and human studies suggest that antibody avidity may be augmented by limiting access to antigen. The primary objective of this study was to evaluate in primed Swedish adults if booster vaccination with fractional doses (1/5th and 1/25th) of a model oral vaccine, the cholera vaccine Dukoral®, results in higher avidity antibody...
Tue Nov 05, 2019 00:00
In this study, we evaluated the genetic stability of the recombinant vaccine after eight serial passages in embryonated chicken eggs (ECE). The vaccine master seed virus at the original egg-passage level 3 (EP3) was diluted and passaged in three separate repetitions (A, B and C) in ECE eight times (EP4 to EP11). RT-PCR analysis of the vaccine seed and egg-passaged virus stocks showed that there was no detectable insertion/deletion in the ILTV gD insert region. Next-generation sequencing analysis...
Tue Nov 05, 2019 00:00
Background: Clinical observations suggest that many patients with obsessive-compulsive disorder (OCD) suffer from severe feelings of guilt. These observations, which are consistent with psychoanalytic assumptions (overly strict super-ego), have rarely been subjected to systematic empirical investigation. Even cognitive approaches broach the issue of guilt as a facet of OCD only indirectly. The purpose of our research was to investigate whether more patients with OCD report feelings of guilt as compared...
Tue Nov 12, 2019 11:30
Hintergrund: Trotz vielfach belegter Wirksamkeit expositionsbasierter Methoden bei Angststörungen werden diese in verhaltenstherapeutischen Praxen häufig nicht oder nicht vertieft genug umgesetzt. Planungs- und Zeitaufwand sind häufige Hinderungsgründe. In dieser Studie wurden Usability (Gebrauchstauglichkeit), User Experience (Nutzererleben) und Nutzerakzeptanz eines Systems zur Fernbegleitung von Expositionstherapie mittels Smart Glass evaluiert. Methoden: In einer standardisierten Laboruntersuchung...
Tue Nov 12, 2019 10:44
Abstract Medical conditions involving the hair are typically managed by a dermatologist. However, a significant psychosocial association has been found both in the development of hair conditions through primary pathologic involvement and as secondary co‐morbidity. Trichopsychodermatology is an emerging field aiming to better understand the psychiatric and psychosocial impact of disorders involving the hair. Trichotillomania or hair‐pulling disorder, alopecia areata, telegenic effluvium, anagen effluvium,...
Tue Nov 12, 2019 18:09
Abstract Background Itch is the most bothersome symptom in psoriasis, often leading to impaired quality of life. Treatment of psoriasis‐induced itch is frequently unsatisfactory as the various therapies employed have a delayed onset of effect. Histamine‐1 receptor (H1)‐antihistamines are not recommended in treatment guidelines as histamine is not considered a key mediator in psoriasis. However, patients using H1‐antihistamines frequently report benefits in questionnaire‐based studies. To address...
Tue Nov 12, 2019 18:04
Abstract Introduction Hori's nevus is a pigmentation disorder reported mainly in middle‐aged Asian women. There is no systematic review addressing its pharmacotherapy. Materials and methods The population for our systematic review was patients with a clinical/ histological diagnosis of Hori's nevus (both sex, any age group). We screened 5 literature databases using relevant keywords. All RCTs, observational studies and case series mentioning at least one intervention and outcome of that...
Tue Nov 12, 2019 18:03
Το δίκτυο υγιών πόλεων απασχόλησε τη σύσκεψη και συνέντευξη μεταξύ του ΕΔΔΥΠΙΠΥ και του ΙΣΑ όπου μίλησαν οι πρόεδροι, Γιώργος Πατούλης, Περιφερειάρχη Αττικής,και Ελένη Γιαμαρέλλου, Καθηγήτρια Παθολογίας ΕΚΠΑ, Λοιμωξιολόγος και Πρόεδρο της Ελληνικής Εταιρείας Χημειοθεραπείας, τον Αθανάσιο Σκουτέλη Καθηγητή και Συντονιστή Διευθυντή Ε΄ Παθολογικής Κλινικής, νοσοκομείου Ευαγγελισμού και Μέλους της Ελληνικής Εταιρείας Λοιμώξεων και την Κυριακή Κανελλακοπούλου, Καθηγήτρια Παθολογίας – Λοιμώξεων ΕΚΠΑ και...
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