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ConclusionThe majority of our respondents perform a large proportion of the SRP surgeries in the UK with each of the respondents performing an average of 40 SRP surgeries per year. There is a need to recatergorise functional septorhinoplasty as a functional operation and recommend functional SRP surgery to be removed from the PoLCV list. (Source: European Archives of Oto-Rhino-Laryngology)
Tue Nov 12, 2019 00:00
ConclusionGP regimen is more cost-effective compared with FP regimen as the first-line treatment for Chinese patients with metastatic NPC. (Source: European Archives of Oto-Rhino-Laryngology)
Tue Nov 12, 2019 00:00
ConclusionsBetter hearing outcomes were obtained with SSCG than with PPORP. SSCG can be used as an alternative hearing reconstruction technique in cases of type 3 tympanoplasty. (Source: European Archives of Oto-Rhino-Laryngology)
Tue Nov 12, 2019 00:00
Taher, Inc., in conjunction with Mann Packing Co., as part of a multi-state recall due to the potential risk of Listeria monocytogenes, in an abundance of caution is announcing a voluntary recall of vegetable cups served in select locations in Minnesota.
Tue Nov 12, 2019 21:09
Amneal Pharmaceuticals, LLC. Bridgewater, New Jersey is voluntarily recalling Ranitidine Tablets, 150 mg and 300 mg, and Ranitidine Syrup (Ranitidine Oral Solution, USP), 15 mg/mL to the consumer level. A listing of the recalled lots is identified below. Ranitidine Tablets, USP, 150 mg and 300 mg
Tue Nov 12, 2019 21:13
Publication date: Available online 12 November 2019Source: Free Radical Biology and MedicineAuthor(s): Justine M. Abais-Battad, Hayley Lund, John Henry Dasinger, Daniel J. Fehrenbach, Allen W. Cowley, David L. MattsonAbstractPrevious studies utilizing the SSp67phox−/− rat have demonstrated the importance of systemic NADPH oxidase NOX2-derived reactive oxygen species (ROS) production in the pathogenesis of Dahl Salt-Sensitive (SS) hypertension and renal damage. It is established that the immune system...
Tue Nov 12, 2019 17:38
Mixture models of item response theory (IRT) can be used to detect inappropriate category use. Data collected by panel surveys where attitudes and traits are typically assessed by short scales with many response categories are prone to response styles indicating inappropriate category use. However, the application of mixed IRT models to this data type can be challenging because of many threshold parameters within items. Up to now, there is very limited knowledge about the sample size required for...
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BackgroundKnowledge about non-surgical weight loss (WL) is scarce among people with severe obesity (SO). Lifestyle changes are primarily self-driven, occasionally accompanied by professional guidance and weight-management support. Weight regain and intervention discontinuation are common challenges among guidance and support programmes. In the current study, we describe a model of meaningful strategies for maintaining WL after SO based on the experiences of successful cases.MethodsAiming to investigate...
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BackgroundAttentional bias modification (ABM) aims to reduce anxiety by attenuating bias toward threatening information. The current study incorporated virtual reality (VR) technology and three-dimensional stimuli with a dot-probe task to evaluate the effects of a VR-based ABM training on attentional bias and anxiety symptoms.MethodsA total of 100 participants were randomized to four training groups. Attentional bias was assessed at pre- and post-training, and anxiety symptoms were assessed at pre-training,...
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In the last decade, the Achievement Orientation Model (AOM) of Siegle and McCoach has often been used to quantitatively explore different pathways for academic achievement among intellectually gifted students in educational settings, mostly in secondary education. To study the dynamics of the different components in the AOM, we further examined the inhibiting and facilitating factors associated with academic achievement as experienced by well-performing and underperforming gifted students. Because...
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Obesity rates among children have climbed dramatically in the past two decades, a time period in which children also experienced greater exposure to portable media devices and smartphones. In the present study, we provide evidence of a potential link between media multitasking – using and switching between unrelated forms of digital media – and risk for obesity, as indexed by body mass index (BMI). Specifically, we recruited 179 pre-adolescent children (aged 9–11 years, 88 females) to participate...
07:04
The skills of thinking, reading conceptions and reading practice (literacy levels) found in textbook activities for the sixth year of Primary Education in Social Sciences and Spanish Language in Spain are analyzed in this paper. A mixed methodology is used to triangulate the data, integrating the critical analysis of discourse and two types of statistical analysis: descriptive (frequencies and percentages) and inferential (χ2, ANOVA, and the Mann-Whitney U Test). The results inform us of both the...
07:04
Publication date: Available online 11 November 2019Source: Journal of Functional FoodsAuthor(s): Shigenobu Ina, Aya Hamada, Hanae Nakamura, Yusuke Yamaguchi, Hitoshi Kumagai, Hitomi KumagaiAbstractThe mechanism of the suppressive effect of rice albumin (RA) on postprandial hyperglycemia after glucose loading was investigated. In order to examine if small peptides derived from RA are responsible for prevention of postprandial hyperglycemia, RA was hydrolysed to indigestible high-molecular-weight peptides...
Tue Nov 12, 2019 17:36
Publication date: Available online 11 November 2019Source: Journal of Functional FoodsAuthor(s): Di Tang, Yihua Wang, Wenyan Kang, Jiannan Zhou, Rui Dong, Qiang FengAbstractChitosan has been applied as a food additive due to its prebiotic functions, while the relationship between changes in the intestinal microbiota caused by chitosan and weight loss remains unclear. This study confirmed the weight control effect of chitosan in the context of high-fat diet consumption. Interestingly, chitosan increased...
Tue Nov 12, 2019 17:36
Future Oncology, Ahead of Print.
Tue Nov 12, 2019 06:17
Immunotherapy, Ahead of Print.
Tue Nov 12, 2019 14:02
The ecological approach is a framework for studying the behavior of animals in their environments. My version of an ecological approach focuses on learning in the context of development. I argue that the most important thing animals learn is behavioral flexibility. They must acquire the ability to flexibly guide their behavior from moment to moment in the midst of developmental changes in their bodies, brains, skills, and environments. They must select, modify, and create behaviors appropriate to...
Tue Nov 12, 2019 16:48
An underlying process metaphysics is, arguably, necessary, but it is not sufficient for understanding the world, and, in particular, for understanding the mind and its development. It is necessary for both logical and empirical reasons, but we also need to account, within such a dynamic framework, for emergent normativity, adaptability, and cognition, among other phenomena, in order to model development. I will sketch these arguments, and then outline a model of development within that framework,...
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Human-level recognition of blast cells in acute myeloid leukaemia with convolutional neural networks
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The association between total homocysteine and blood pressure in two independent Chinese populations
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Rift Valley Fever -- KenyaWhile addressing a County Steering Group (CSG) meeting on Friday [8 Nov 2019], the [Laikipia] County Livestock Production Officer (CLPO), Pius Butich, said that "the current meteorological reports have created alerts for Rift Valley fever [RVF], which is the most dangerous zoonotic disease."He proposed the need to put in place an early warning system on high alert as part of measures to protect both livestock and humans against the disease.Butich said all field staff, public...
01:14
Botulism -- United StatesSeveral Western gulls which were found dead on Huntington Beach last month [Oct 2019] have unexpectedly tested positive for a type of botulism which is more commonly detected in humans.The nonprofit Wetland and Wildlife Care Center (WWCC) initially reported that 8 Western gulls were discovered dead, and 4 more in critical condition, on [10 Oct 2019] at high tide on Huntington Beach. The 4 gulls found alive were unable to move or close their eyes. One of them died and the...
Tue Nov 12, 2019 23:13
Chikungunya -- Honduras[Editorial]-----------"Doctor, I will never normally work and live again; joint pain prevents me that." This was expressed by a patient in La Virginia, Colombia 3 years after having been infected with chikungunya virus (CHIKV).After more than 5 decades of obscurity, probably due to lack of studies, many clinical consequences of CHIKV began to be reported, particularly rheumatic ones, after the outbreaks in Réunion Island and India (Javelle et al, 2015) during the epidemic wave...
Tue Nov 12, 2019 20:47
Scrub Typhus -- IndiaThe ProMED-mail post erroneously identified this report as being dated Fri 8 Nov 2019. However, this news report actually was dated Sat 8 Sep 2018. We apologize for this error.--Communicated by:ProMED-mail[See Also:Scrub typhus - India (06): (MH) fatal
Tue Nov 12, 2019 18:09
Legionnaires' -- United StatesThe Tyler Morning Telegraph has learned [a man] died [Fri 8 Nov 2019] around 9:45 p.m. His family told reporter Cory McCoy he was fighting for his life after complications from legionnaires' disease and had been in and out of the hospital. They confirmed late Friday he passed away.The family said they believe he contracted the disease at East Texas State Fair more than a month and a half ago.[The man], a well-known volunteer, community leader and the precinct chair for...
Tue Nov 12, 2019 16:59
Γράφει ο Στυλιανός Λουκίδης, Πνευμονολόγος Το άσθμα χαρακτηρίζεται από φλεγμονή των αεραγωγών (βρόγχων), οι οποίοι είναι οι σωλήνες που μεταφέρουν τον αέρα στους πνεύμονες. Το άσθμα είναι μια χρόνια φλεγμονώδης νόσος, η οποία έχει εκλυτικούς παράγοντες που είτε συμβάλλουν στην παθογένεσή της, είτε την αποσταθεροποιούν (απώλεια ελέγχου), είτε την παροξύνουν. Οι ιώσεις συμμετέχουν με ένα ιδιαίτερα σημαντικό ρόλο σε όλο αυτό το φάσμα. Γι’ αυτό και όταν ένας ασθενής με άσθμα προσβάλλεται από αυτές...
Tue Nov 12, 2019 21:55
Γράφει ο Νικόλαος Τεντολούρης, Καθηγητής Παθολογίας Τα τελευταία χρόνια έχει γίνει μεγάλη πρόοδος στην κατανόηση της παθογένειας των προβλημάτων του Διαβητικού Ποδιού. Σήμερα γίνεται έρευνα σε παγκόσμια κλίμακα στον τομέα της πρόληψης με κύριο σημείο τη μείωση των ακρωτηριασμών, αφού εντοπισθούν τα άτομα που αντιμετωπίζουν αυξημένο κίνδυνο. Ο όρος “Σύνδρομο Διαβητικού Ποδιού” περιλαμβάνει έλκη, λοιμώξεις και γάγγραινα που συνδυάζονται με την παρουσία περιφερικής νευροπάθειας και περιφερικής αγγειοπάθειας....
Tue Nov 12, 2019 21:31
O ιός του κοινού κρυολογήματος χρειάζεται περίπου 3-4 μέρες για να κάνει τον κύκλο του, ωστόσο αυτό εξαρτάται από την κατάσταση του ανοσοποιητικού σας συστήματος και από το αν είστε καπνιστής. Ειδικά στη δεύτερη περίπτωση, η ταλαιπωρία μπορεί να κρατήσει διπλάσιο χρόνο. Υπάρχουν πάνω από 200 ιοί του κοινού κρυολογήματος που προσβάλλουν τον ανθρώπινο οργανισμό, με τους περισσότερους να στοχεύουν το αναπνευστικό σύστημα. Αν τις πρώτες 24 ώρες από την εμφάνιση των πρώτων συμπτωμάτων υπάρξει η σωστή...
Tue Nov 12, 2019 21:02
Αμερικανική μελέτη βρήκε ότι τα μοναχοπαίδια έχουν χειρότερες συνήθειες διατροφής και επιλογές ροφημάτων και χαμηλότερη βαθμολογία στον Δείκτη Υγιεινής Διατροφής, σε σχέση με τα παιδιά που έχουν αδέλφια. Η μελέτη δημοσιεύθηκε στο Journal of Nutrition Education and Behavior. Η σημαντικά χαμηλότερη βαθμολογία αφορούσε όλες τις ημέρες της εβδομάδας και τα Σαββατοκύριακα, υποδεικνύοντας σε γενικές γραμμές ότι υπάρχουν τόσο ατομικές όσο και συλλογικές διαφορές στα διατροφικά μοτίβα μεταξύ των οικογενειακών...
Tue Nov 12, 2019 20:44
Σε συνέχεια της σημερινής δημοσίευσης της έκθεσης της IQVIA για την «Αξιολόγηση των Ανθρωποκεντρικών Θεραπευτικών Καινοτομιών», η EFPIA κάνει έκκληση να συμπεριληφθούν τόσο η εμπειρία όσο και οι προτιμήσεις του ασθενούς στην αξιολόγηση της καινοτομίας μέσα από τη διαδικασία της Αξιολόγησης Τεχνολογιών Υγείας (ΗΤΑ) και της διαπραγμάτευσης, καθώς μόνο αυτοί μέσα από βιωματικές εμπειρίες μπορούν να αποτυπώσουν την προστιθέμενη αξία των θεραπειών. Οι ανθρωποκεντρικές θεραπευτικές καινοτομίες μπορούν...
Tue Nov 12, 2019 17:59
Οι γυναίκες με πρόωρη εμμηνόπαυση (πριν τα 40) διατρέχουν αυξημένο κίνδυνο εμφάνισης καρδιαγγειακών ασθενειών, όπως αποκαλύπτει νέα έρευνα η οποία uα παρουσιαστεί στο ετήσιο συνέδριο της Αμερικανικής Καρδιολογικής Εταιρείας που θα διεξαχθεί στις 16-18 Νοεμβρίου 2019, στη Φιλαδέλφεια. Ο Michael Honigberg, επικεφαλής συντάκτης της μελέτης και καρδιολόγος στο Πανεπιστήμιο του Χάρβαρντ, στη Βοστόνη και στο Γενικό Νοσοκομείο της Μασαχουσέτης, εξήγησε ότι είναι πολύ σημαντικό ο γιατρός να γνωρίζει το...
Tue Nov 12, 2019 13:40
«Εμπόδισε την εμφάνιση του στην δική σου Οικογένεια», είναι για 2η χρονιά το μήνυμα της ενημερωτικής εκστρατείας κατά του διαβήτη της Ελληνικής Διαβητολογικής Εταιρείας (ΕΔΕ), στο πλαίσιο της Παγκόσμιας Ημέρας Διαβήτη (14 Νοεμβρίου). Στόχος της εκστρατείας είναι η ευαισθητοποίηση του κοινού για τις επιπτώσεις του Σακχαρώδη Διαβήτη (ΣΔ) καθώς και η ανάδειξη και ενίσχυση του ρόλου της Οικογένειας στην Πρόληψη, Διαχείριση, Φροντίδα, και Εκπαίδευση, αναφορικά με το νόσημα. «Ο Διαβήτης αφορά κάθε...
Tue Nov 12, 2019 13:23
Τροπολογία που αλλάζει τους κανόνες της τιμολόγησης κατέθεσε το υπουργείο Υγείας σε νομοσχέδιο του υπουργείου Οικονομικών που βρίσκεται στη διαδικασία συζήτησης στις επιτροπές. Με την πρώτη διάταξη της τροπολογίας ρυθμίζεται ότι κατά τη διαδικασία διαμόρφωσης νέων τιμών δεν θα λαμβάνονται υπόψη για τη διαμόρφωση του κόστους, στοιχεία και δείγματα, χορηγούμενα άνευ εγκρίσεως του ΕΟΦ. Με τη δεύτερη διάταξη προβλέπεται, ότι ως τιμή διαμόρφωσης του φαρμάκου θα ορίζεται ο μέσος όρος των δύο χαμηλότερων...
Tue Nov 12, 2019 12:58
Η καρδιακή προσβολή συνδέεται με αυξημένο κίνδυνο ανάπτυξης καρκίνου στο μέλλον. Μια υψηλή βαθμολογία για τον 10ετή κίνδυνο αθηροσκληρωτικής καρδιαγγειακής νόσου (ASCVD: atherosclerotic cardiovascular disease) τριπλασιάζει τον κίνδυνο εμφάνισης καρκίνου. Η σχετική μελέτη θα παρουσιαστεί στις Επιστημονικές Συνεδρίες της American Heart Association 2019, στις 16-18 Νοεμβρίου, στη Φιλαδέλφεια. Τα άτομα με υψηλότερο κίνδυνο για καρδιαγγειακά νοσήματα έχουν υψηλότερο κίνδυνο εμφάνισης καρκίνου. Επίσης,...
Tue Nov 12, 2019 10:21
Η εφαρμογή της κατευθυντήριας γραμμής του 2013 από τα American College of Cardiology / American Heart Association για τη μείωση της χοληστερόλης στο αίμα οδήγησε σε βελτίωση των ολικών επιπέδων χοληστερόλης για τους Αμερικανούς ενήλικες που λαμβάνουν στατίνες. Η μελέτη εξέτασε τον αντίκτυπο της κατευθυντήριας γραμμής μερικά χρόνια μετά την έκδοσή της και δημοσιεύθηκε στο Journal of the American College of Cardiology. Όταν δημοσιεύθηκε το 2013, η κατευθυντήρια γραμμή των ACC / AHA για τη χοληστερόλη...
Tue Nov 12, 2019 09:13
Traumatic joint injury is known to cause cartilage deterioration and osteoarthritis. In order to study the mechanical mechanism of damage evolution on articular cartilage, taking the fresh porcine articular cartilage as the experimental samples, the creep experiments of the intact cartilages and the cartilages with different depth defect were carried out by using the noncontact digital image correlation technology. And then, the creep constitutive equations of cartilages were established. The results...
09:05
Hydraulic modelling is now, at increasing rates, used all over the world to provide flood risk maps for spatial planning, flood insurance, etc. This puts heavy pressure on the modellers and analysts to not only produce the maps but also information on the accuracy and uncertainty of these maps. A common means to deliver this is through performance measures or feature statistics. These look at the global agreement between the modelled flood area and the reference flood that is used. Previous studies...
09:05
Alveolar hemorrhage is the rarest pulmonary complication of catastrophic antiphospholipid syndrome and is associated with high mortality risk. This life-threatening complication results from autoimmune damage to the alveolar blood vessels. Given the limited literature addressing the association of these two pathologies, we report a series of three cases with this complication and then compare our findings with 6 cases reported in the literature.
09:05
Treatment of severe malaria with artemisinin derivatives in patients with comorbid conditions such as sickle cell anemia must be considered with precaution. We report here a case of possibly undocumented ventricular arrhythmia in a sickle cell anemia patient diagnosed with Plasmodium falciparum malaria and treated with intravenous artesunate. The patient suffered from wide complex tachycardia after treatment with artesunate 170 mg (2.4 mg/kg) i.v. bolus, tachycardia was managed with amiodarone (150 mg...
09:05
Nowadays, the gaseous pollutant emissions, including particulate matter (PM), sulfur dioxide (SO2), and nitrogen oxide (NOx) from household coal combustion, cause great threat to environment and public health by contributing to severe haze in China. Particularly, a clean coke free of the major pollutants precursors (sulfur and nitrogen compounds) by sulfur fixation and denitrification has been deemed as an effective strategy to reducing pollutants. In this paper, a preprocessed coke was prepared...
09:05
Background. Anaemia in children is a significant health problem that receives little attention. This study aimed at determining the factors significantly associated with anaemia in children aged 6 to 59 months in Kenya, Malawi, Tanzania, and Uganda while accounting for the spatial heterogeneity within and between the districts of the four countries. In addition, the performance of the districts with regard to their impact on anaemia was assessed and ranked. Methods. A generalised additive mixed model...
09:05
Determining insulin requirements for hemodialysis patients with end-stage renal disease (ESRD) is difficult. We performed a randomized crossover study among type 2 diabetes (T2DM) patients with ESRD on continuous hemodialysis and receiving standard insulin for glycemic control. The patients were randomized in 2 groups: daily insulin needed on the day after hemodialysis and a 25% decrease in daily insulin needed on the day after hemodialysis. A total of 51 T2DM patients with ESRD were enrolled. The...
08:05
The resistance of malaria parasites to the current antimalarial drugs has led to the search for novel effective drugs. Betula alnoides has been traditionally used for the treatment of malaria, but the scientific evidence to substantiate this claim is still lacking. Therefore, the present study aimed at evaluating the antimalarial activity and toxicity of an aqueous stem extract of B. alnoides in a mouse model. The in vivo antimalarial activity of an aqueous stem extract of B. alnoides was determined...
08:05
Inflammation plays a pivotal role in the development of pulmonary arterial hypertension (PAH). Meanwhile, serum glucocorticoid-regulated kinase-1 (SGK1) has been considered to be an important factor in the regulation of inflammation in some vascular disease. However, the role of SGK1 in hypoxia-induced inflammation and PAH is still unknown. WT and SGK1-/- mice were exposed to chronic hypoxia to induce PAH. The quantitative PCR and immunohistochemistry were used to determine the expression of SGK1....
07:05
This study presents a comparative analysis of the deformation control effect of the hydraulic servo steel struts and ordinary steel struts of a foundation pit based on the measured axial force of the steel struts, lateral wall deflection, and ground surface settlement due to pit excavation. The results indicate that ordinary steel struts installed via axial preloading exhibit a disadvantageous axial force loss with a maximum value equal to 86.7% of the axial preloading force. When compared with ordinary...
07:05
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