Stowe RC. Acute drug-induced symptoms of restless legs syndrome in an emergency department: what's in a name? J Clin Sleep Med. 2019;15(9):1381.
Mu S, Howard ME, Hannan L. Autocycling during noninvasive positive pressure ventilation producing a prolonged severe apnea and syncope, further insights. J Clin Sleep Med. 2019;15(9):1379.
Karim HMR, Esquinas AM. Autocycling during noninvasive positive pressure ventilation as a factor for severe syncope: exciting observation, but needs more scrutiny. J Clin Sleep Med. 2019;15(9):1377.
Lobl M, Zandieh SO. Obstructive sleep apnea as the first presentation of juvenile nasal angiofibroma. J Clin Sleep Med. 2019;15(9):1373–1375.
Idiopathic rapid eye movement sleep behavior disorder is characterized by vocalizations and complex motor behaviors during sleep. We report a case of a 44-year-old male with a 20-year history of dream enactment behavior that was incidentally captured on a polysomnogram during an evaluation for obstructive sleep apnea. Genetic testing found the patient had a homozygous deletion for one of the five tandem repeats in exon 18 of the PER3 gene. This case highlights a potential genetic basis for idiopathic...
Excessive daytime sleepiness (EDS) is one of the leading reasons that patients present to sleep clinics. Approximately 10% to 14% of the adults report that excessive sleepiness interferes with their daily lives. Common causes of EDS include obstructive sleep apnea, sleep deprivation, circadian rhythm disorders, medication effects, psychiatric conditions especially depression, and primary hypersomnia such as narcolepsy or central idiopathic hypersomnia. Vitamin B12 deficiency is a rare cause of EDS....
Study Objectives:(1) Review the prevalence and comorbidity of sleep disorders among United States military personnel and veterans. (2) Describe the status of sleep care services at Veterans Health Administration (VHA) facilities. (3) Characterize the demand for sleep care among veterans and the availability of sleep care across the VHA. (4) Describe the VA TeleSleep Program that was developed to address this demand.Methods:PubMed and Medline databases (National Center for Biotechnology Information,...
Study Objectives:To quantitatively evaluate the functional integrity of sensory nerve fibers of the palate in patients with obstructive sleep apnea (OSA) using the Neurometer system.Methods:A total of 32 patients with OSA and 18 healthy control patients were included in the study. All participants were selected based on medical history, physical examination, and nocturnal polysomnography (PSG) and divided into two groups. The palatal sensory status of participants was examined with a Neurometer current...
Study Objectives:To compare the quality and consistency in sleep measurement of a consumer wearable device and a research-grade actigraph with polysomnography (PSG) in adolescents.Methods:Fifty-eight healthy adolescents (aged 15–19 years; 30 males) underwent overnight PSG while wearing both a Fitbit Alta HR and a Philips Respironics Actiwatch 2 (AW2) for 5 nights, with either 5 hours or 6.5 hours time in bed (TIB) and for 4 nights with 9 hours TIB. AW2 data were evaluated using two different wake...
Study Objectives:There is growing evidence to support sleep impairment as a core feature of posttraumatic stress disorder (PTSD). Sleep impairment in PTSD is associated with severe distress and poorer treatment outcomes. Therefore, specific attention to this symptom of PTSD is warranted and accurate assessment of sleep impairment is critical. The current study investigated the association between self-reported and objective assessment of sleep and sustained attention in women with PTSD.Methods:Study...
Study Objectives:We hypothesized that sleep duration in the Amish would be longer than in non-Amish.Methods:Sleep duration was obtained by questionnaire administered to Amish individuals (n = 3,418) and from the 2015–2016 National Health and Nutrition Examination Survey (NHANES; n = 1,912). Self-reported sleep duration was calculated as the difference in usual times that the participants went to bed at night and woke up in the morning.Results:In Amish (43.7 ± 16.7 years) and NHANES (50.0 ± 20.6 years),...
Study Objectives:To determine the effect of continuous positive airway pressure (CPAP) treatment on health-related quality of life (HRQoL) in adults with coronary artery disease (CAD) and nonsleepy obstructive sleep apnea (OSA).Methods:This was a secondary outcome analysis of the RICCADSA trial, conducted in Sweden between 2005 and 2013. Adults with CAD, nonsleepy OSA (apnea-hypopnea index [AHI] ≥ 15 events/h; Epworth Sleepiness Scale [ESS] score < 10) and complete Short-Form (SF)-36 questionnaires...
Study Objectives:Postpartum depression (PPD) occurs in 15% to 20% of mothers worldwide and is associated with adverse outcomes for mother and child. Prior research has established a relationship between concurrent sleep quality and PPD. We conducted a secondary analysis in 45 women with mood disorders to study overall sleep quality (and individual components of sleep), measured in the early postpartum period, as a predictor of subsequent PPD.Methods:We measured sleep quality using the Pittsburgh...
Study Objectives:Several studies have reported an association between obstructive sleep apnea (OSA) and neuro-otologic diseases, such as Ménière’s disease or sudden sensorineural hearing loss (SSNHL). However, the exact relationship between OSA and those diseases has not been fully evaluated. Therefore, the aim of this study was to investigate the prospective link between OSA and Ménière’s disease or SSNHL.Methods:We used a nationwide cohort sample of data for 2002–2013 representing approximately...
Study Objectives:The safety profile of the dual orexin receptor antagonists (DORAs) are currently unknown with regard to nocturnal responsivity among people with insomnia. We compared the auditory awakening thresholds (AATs) of the DORA suvorexant (10 and 20 mg) versus placebo in 12 individuals with DSM-5 insomnia.Methods:The study used a double-blind, placebo-controlled, three-way crossover design. Participants were randomly assigned to a treatment sequence that included placebo, suvorexant 10 mg,...
Study Objectives:Drowsiness leads to 20% of fatal road crashes, while inability to assess drowsiness has hampered drowsiness interventions. This study examined the accuracy of eye-blink parameters for detecting drowsiness related driving impairment in real time.Methods:Twelve participants undertook two sessions of 2-hour track-driving in an instrumented vehicle following a normal night’s sleep or 32 to 34 hours of extended wake in a randomized crossover design. Eye-blink parameters and lane excursion...
Study Objectives:The association between obstructive sleep apnea (OSA) and hypertension in prior studies has been determined using a definition of hypopnea requiring a 4% O2 desaturation. However, the American Academy of Sleep Medicine (AASM) recommends using a 3% O2 desaturation or an arousal. This analysis assesses the relationship between OSA and hypertension utilizing the AASM recommended definition and the 2018 American College of Cardiology/American Heart Association hypertension guidelines.Methods:Data...
Study Objectives:Adenotonsillectomy (AT) is the treatment of choice for obstructive sleep apnea (OSA) in children with adenotonsillar hypertrophy. Severe OSA, identified by the apnea-hypopnea index (AHI), is a risk factor for surgical complications and AHI thresholds are used by surgeons to decide elective postoperative hospital admissions. The objective of this study was to identify the prevalence of surgical complications of AT in children with severe OSA and determine their association with specific...
Study Objectives:The current value-based medical climate has led to scrutiny of all medical costs. Given the relationship between obstructive sleep apnea (OSA) and many significant comorbid medical conditions, treating patients with OSA via positive airway pressure (PAP) therapy might reduce health care expenditures. Our goal was to determine the relationship between PAP use and acute care utilization and costs.Methods:This was a retrospective cohort study of adult patients who initiated PAP therapy...
Study Objectives:The association between posttraumatic stress disorder (PTSD) and obstructive sleep apnea (OSA) has been reported inconsistently, and the association between antidepressant use and the risk of developing OSA in patients with PTSD has not been previously studied. Therefore, we used the Longitudinal National Health Insurance Database (LHID) to investigate the impact of PTSD and antidepressant use on the risk of OSA development.Methods:Identified from the LHID, 2,316 individuals aged...
Study Objectives:Published literature documents increased risk for psychiatric adverse events (P-AEs) following dopamine agonist (DA) initiation for treatment of primary restless legs syndrome (RLS). We examined the association between DA initiation and subsequent new-onset P-AEs among patients with a new diagnosis of RLS who had no history of psychiatric disorder or DA use.Methods:Selected were adults (age 18 years or older) enrolled through United States employer-sponsored plans and Medicare Advantage...
Study Objectives:Insomnia disorder (ID) is highly associated with Parkinson disease (PD) with great negative effect on health-related quality of life. Nonetheless, the relevance of psychological processes involved in the maintenance of insomnia is yet to be established in the context of this neurological condition. Our aim was to examine a serial meditation model of sleep-related safety behaviors and dysfunctional beliefs about sleep in association with presleep cognitive arousal and ID in patients...
Study Objectives:In nightmare etiology, trait and state factors play important roles. However, the interaction of state and trait factors has never been studied in a longitudinal design.Methods:The current sample included 406 pregnant women who were followed up approximately 6 months after giving birth (n = 375) and 4 years later (n = 302). A nightmare frequency scale and several stress-related questionnaires were presented at three measurement points.Results:Despite the major life events in this...
Study Objectives:This secondary analysis characterized sleep patterns for toddlers born preterm and tested effects of docosahexaenoic acid (DHA)+ arachidonic acid (AA) supplementation on children’s caregiver-reported sleep. Exploratory analyses tested whether child sex, birth weight, and caregiver depressive symptomatology were moderators of the treatment effect.Methods:Omega Tots was a single-site 180-day randomized (1:1), double-blinded, placebo-controlled trial. Children (n = 377) were age 10...
Colvin L. Telehealth: helping solve a problem we created. J Clin Sleep Med. 2019;15(9):1195–1196.
Weaver TE. Do we finally know whether CPAP improves quality of life in non-sleepy patients? J Clin Sleep Med. 2019;15(9):1193–1194.
Rizzo D, Baltzan M. An objective measure of drowsy driving: are we there yet? J Clin Sleep Med. 2019;15(9):1191–1192.
Javaheri S, Gay PC. To die, to sleep – to sleep, perchance to dream…without hypertension: dreams of the visionary Christian Guilleminault revisited. J Clin Sleep Med. 2019;15(9):1189–1190.
Kirsch DB. Disruption in health care (and sleep medicine): “it’s the end of the world as we know it…and I feel fine.”. J Clin Sleep Med. 2019;15(9):1185–1188.
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Abstract Objectives To investigate the effects on pain, movement kinematics, and cerebral representation by a 3-month mandibular splint therapy. Material and methods Thirteen patients with temporo-mandibular joint disease (TMD) and moderate pain intensity were investigated before (PRE), within (after 2 weeks, POST1) and after a period of 12 weeks (POST2)...
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Laryngo-Rhino-OtolDOI: 10.1055/a-0996-1087Ein 96-jähriger Patient wurde durch den niedergelassen HNO-Facharzt mit Verdacht auf einen Stimmlippenpolypen in die Hochschulambulanz überwiesen. Er litt seit ca. vier Monaten unter Heiserkeit und verminderter stimmlicher Belastbarkeit. Weitere Symptome wie Dyspnoe, Dysphagie, Schmerzen oder eine B-Symptomatik bestanden nicht. Es lagen weder Nikotin- noch Alkoholabusus vor.[...]© Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table...
Laryngo-Rhino-OtolDOI: 10.1055/a-1007-1913© Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents | Full text
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Journal of the American Chemical SocietyDOI: 10.1021/jacs.9b07448
Journal of the American Chemical SocietyDOI: 10.1021/jacs.9b07986
Journal of the American Chemical SocietyDOI: 10.1021/jacs.9b08634
Journal of the American Chemical SocietyDOI: 10.1021/jacs.9b04729
Journal of the American Chemical SocietyDOI: 10.1021/jacs.9b08273
Journal of the American Chemical SocietyDOI: 10.1021/jacs.9b06794
Journal of the American Chemical SocietyDOI: 10.1021/jacs.9b06064
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