Escalating Mucus Inhibition to the Top of Our Priorities.Related ArticlesEscalating Mucus Inhibition to the Top of Our Priorities. Am J Respir Cell Mol Biol. 2019 Sep;61(3):275-276 Authors: Britto CJ, Cohn L PMID: 31063695 [PubMed - indexed for MEDLINE]- Endoscopic treatment of acquired subglottic stenosis in children: Predictors of success.Related ArticlesEndoscopic treatment of acquired subglottic stenosis in children: Predictors of success. Arch Argent Pediatr. 2018 12 01;116(6):418-425 Authors: Cuestas G, Rodríguez V, Doormann F, Bellia Munzón P, Bellia Munzón G Abstract Subglottic stenosis is a congenital or acquired disease characterized by the narrowing of the airways, from the vocal cords to the lower border of the cricoid carti
- Laryngeal Injury and Upper Airway Symptoms After Oral Endotracheal Intubation With Mechanical Ventilation During Critical Care: A Systematic Review.Related ArticlesLaryngeal Injury and Upper Airway Symptoms After Oral Endotracheal Intubation With Mechanical Ventilation During Critical Care: A Systematic Review. Crit Care Med. 2018 12;46(12):2010-2017 Authors: Brodsky MB, Levy MJ, Jedlanek E, Pandian V, Blackford B, Price C, Cole G, Hillel AT, Best SR, Akst LM Abstract OBJECTIVES: To systematically review the symptoms and types of laryngeal injur
- Impact of Infant Supraglottoplasty on Quality of Life.Related ArticlesImpact of Infant Supraglottoplasty on Quality of Life. Otolaryngol Head Neck Surg. 2018 09;159(3):564-571 Authors: Vandjelovic ND, Brown JR, Traboulsi HT, Thottam PJ Abstract Objectives The objective of the present study is to examine the impact of supraglottoplasty on the quality of life (QOL) of caregivers and infants with severe laryngomalacia and moderate laryngomalacia with feedi
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- Obstructive sleep apnoea in a paediatric patient with laryngeal Crohn's disease.Related ArticlesObstructive sleep apnoea in a paediatric patient with laryngeal Crohn's disease. J Paediatr Child Health. 2018 02;54(2):197-199 Authors: Pervez T, Lee CH, Seton C, Raftopulos M, Birman C, O'loughlin E PMID: 29105889 [PubMed - indexed for MEDLINE]
- Current topics in medicinal chemistry
- Advances in Dopamine D1 Receptor Ligands for Neurotherapeutics.Related ArticlesAdvances in Dopamine D1 Receptor Ligands for Neurotherapeutics. Curr Top Med Chem. 2019;19(16):1365-1380 Authors: Felsing DE, Jain MK, Allen JA Abstract The dopamine D1 receptor (D1R) is essential for neurotransmission in various brain pathways where it modulates key functions including voluntary movement, memory, attention and reward. Not surprisingly, the D1R has been validated as a
- Clinical Therapeutics
- Retrospective Study on the Association of Biomarkers With Real-world Outcomes of Omalizumab-treated Patients With Allergic AsthmaPublication date: Available online 25 September 2019Source: Clinical TherapeuticsAuthor(s): Abhishek Kavati, Maryia Zhdanava, Benjamin Ortiz, Jason Lecocq, Bradd Schiffman, Dominic Pilon, Harriet Ho, Patrick Lefebvre, Brian StoneAbstractPurposeBiomarkers, including blood eosinophils (EoS) and fractional exhaled nitric oxide (FeNO), may affect omalizumab outcomes in allergic asthma, but evidence in the literature remains mixed. This study assessed
- Safe Expectations: Current State and Future Directions for Medication Safety in Pregnancy ResearchPublication date: Available online 25 September 2019Source: Clinical TherapeuticsAuthor(s): Mollie E. Wood, Susan E. Andrade, Sengwee TohAbstractMedication use in pregnancy is common, but information about the safety of most medications in pregnant women or their infants is limited. In the absence of data from randomized clinical trials to guide decisions made by regulators, clinicians, and patients, we often have to rely on well-designed observa
- Cancer Immunology, Immunotherapy
- Activation of dendritic cells by targeted DNA: a potential addition to the armamentarium for anti-cancer immunotherapyAbstract In the past decade, remarkable progress has been made in immunotherapy against cancer. Specifically, the introduction of immune checkpoint inhibitors has revolutionized the field. However, many patients are unable to benefit significantly from this treatment option. One of the major reasons for this is most likely the absence of an adequate tumor-specific T cell response in these patients. A way to circumvent this prob
- Dermatologic Surgery - Current Issue
- Repair of Anterior Ear Defects Using Transcartilage Island Pedicle FlapsBACKGROUND Surgical reconstruction of the anterior surface of the ear (concha, antihelix, scapha, and triangular fossa) is complicated by the paucity of mobile local skin. OBJECTIVE This is a retrospective study of the transcartilage island pedicle flap for reconstruction of surgical defects of the anterior ear. METHODS AND MATERIALS Two hundred thirty-two Mohs micrographic surgery defects were included in the study. The technique in
- Pacemakers, Deep Brain Stimulators, Cochlear Implants, and Nerve Stimulators: A Review of Common Devices Encountered in the Dermatologic Surgery PatientBACKGROUND In dermatologic and procedural surgery settings, there are commonly encountered devices in patients. Safe surgical planning requires familiarity with these devices. OBJECTIVE To review the current implanted devices in patients and recommendations for surgical planning around these devices. METHODS AND MATERIALS A comprehensive review using PubMed and published device recommendations was performed, searching for those most
- Defining Fistular Patterns in Hidradenitis Suppurativa: Impact on the ManagementBACKGROUND Recent studies suggest that there are different fistular subtypes in hidradenitis suppurativa (HS) patients who are associated with variable therapeutic outcomes. OBJECTIVE To describe clinical and ultrasound features that characterize the different fistular patterns in HS and to evaluate the response to medical therapies. METHODS A retrospective study developed by a well-recognized center specialized in HS analyzing both
- Efficacy and Safety of a Sublative Bipolar Fractional Radiofrequency System Combined With Topical Tretinoin in Treating Striae Gravidarum: A Randomized Pilot StudyBACKGROUND Striae gravidarum is a common skin condition resulting after pregnancy, caused by fibroblast dysfunction. Although not considered a disease, it may be considered cosmetically unpleasant to sufferers and remains as a therapeutic challenge to date. OBJECTIVE To evaluate the efficacy and safety of a sublative bipolar fractional radiofrequency (FRF) system, associated with 0.1% topical tretinoin, in treating striae gravidarum. MA
- Combination of Sclerotherapy and Dual-Wavelength Laser in the Management of Infantile Hemangiomas in Chinese InfantsOBJECTIVE To evaluate the efficacy and safety of combination therapy with sclerotherapy and dual-wavelength pulsed dye laser (PDL) & Nd:YAG for infantile hemangiomas (IHs). PATIENTS AND METHODS Fifty-nine patients with IH received treatment with sclerotherapy and dual-wavelength PDL & Nd:YAG treatment at 4-week intervals. Observers assessed the size and color of IH using a size rating scale and color rating scale before and after treatmen
- A Diagnostic Challenge: Changes in Histopathologic Tumor Diagnosis of Atypical Squamous Proliferations After Surgical RemovalBACKGROUND Biopsy-proven “atypical squamous proliferations” (ASPs) may prove difficult to diagnose histologically because of partial sampling, lack of complete criteria for definitive diagnosis, or overlap of histopathological features with other neoplasms. There are no guidelines concerning the management of ASPs. OBJECTIVE To retrospectively clarify the diagnosis of biopsy-proven ASPs after surgical removal, specifically, to ascertain w
- Platelet-Rich Plasma as a Treatment for Androgenetic AlopeciaBACKGROUND Platelet-rich plasma (PRP) treatment may encourage hair growth by promoting cellular maturation, differentiation, and proliferation. OBJECTIVE The objective of this study was to evaluate the effectiveness of PRP as a treatment for androgenetic alopecia (AGA). MATERIALS AND METHODS A literature search combined with meta-analysis was used to calculate the overall standardized mean difference (SMD) in hair density in patients
- Clinical Assessment of 2 Licensed AbobotulinumtoxinA Injection Volumes for the Treatment of Glabellar LinesBACKGROUND Two licensed reconstitution volumes may be used to achieve the recommended abobotulinumtoxinA (ABO) dose for glabellar line correction. OBJECTIVE Comparison of efficacy, safety, and subject satisfaction concerning treatment of moderate to severe glabellar lines with 2 different ABO reconstitution volumes. MATERIALS AND METHODS Phase IV, prospective, randomized, multicenter, subject- and evaluator-blinded study: 60 subjects
- Real-World Experience With 100 Consecutive Patients Undergoing Neck Contouring With ATX-101 (Deoxycholic Acid): An Updated Report With A 2-Year AnalysisBACKGROUND Deoxycholic acid (DCA; ATX-101) injection was approved for the treatment of mild-to-moderate convexity associated with submental fat in 2015. OBJECTIVE To evaluate the experience with DCA injections in a clinical practice setting. MATERIALS AND METHODS This ongoing, prospective, single-center, single-arm, observational study evaluated 100 consecutive patients treated with subcutaneous DCA (2 mg/cm2) injections (maximum 6 s
- Safe, Effective Chin and Jaw Restoration With VYC-25L Hyaluronic Acid Injectable GelBACKGROUND VYC-25L, a hyaluronic acid soft-tissue filler with lidocaine, is designed to restore and create facial volume in the chin and jaw. OBJECTIVE To evaluate the safety and effectiveness of VYC-25L in subjects with chin retrusion. METHODS Adults with chin retrusion (145°–165° glabella–subnasale–pogonion facial angle) were randomized (3:1) to receive VYC-25L in the chin/jaw at study onset (treatment group) or 3 months later (con
- Efficacy and Safety of 3 New Resilient Hyaluronic Acid Fillers, Crosslinked With Decreased BDDE, for the Treatment of Dynamic Wrinkles: Results of an 18-Month, Randomized Controlled Trial Versus Already Available ComparatorsBACKGROUND Three new hyaluronic acid (HA)-based fillers made of long chains crosslinked with reduced amounts of 1,4-butanediol diglycidyl ether (BDDE) were developed for the treatment of dynamic facial areas. Their resilience and increased stretching ability were optimized to ease injectors' practice and provide patients with most natural aesthetic results. OBJECTIVE This study aimed at evaluating the efficacy, durability, and safety of t
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
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Πέμπτη 26 Σεπτεμβρίου 2019
- Current topics in medicinal chemistry
- Clinical Therapeutics
- Cancer Immunology, Immunotherapy
- Dermatologic Surgery - Current Issue
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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
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Ετικέτες
00302841026182,
00306932607174,
alsfakia@gmail.com,
Anapafseos 5 Agios Nikolaos 72100 Crete Greece,
Medicine by Alexandros G. Sfakianakis
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