Antioxidants, Vol. 8, Pages 431: Moderate Intensity Resistive Training Reduces Oxidative Stress and Improves Muscle Mass and Function in Older Individuals Antioxidants doi: 10.3390/antiox8100431 Authors: Vezzoli Mrakic-Sposta Montorsi Porcelli Vago Cereda Longo Maggio Narici An innovative moderate-intensity resistive exercise-training (RT) program was tested in thirty-five sarcopenic elders (SAR). The subjects were randomized into two groups: SAR training...
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Atmosphere, Vol. 10, Pages 584: Validation of the IPSL Venus GCM Thermal Structure with Venus Express Data Atmosphere doi: 10.3390/atmos10100584 Authors: Pietro Scarica Itziar Garate-Lopez Sebastien Lebonnois Giuseppe Piccioni Davide Grassi Alessandra Migliorini Silvia Tellmann General circulation models (GCMs) are valuable instruments to understand the most peculiar features in the atmospheres of planets and the mechanisms behind their dynamics. Venus makes no exception...
Atmosphere, Vol. 10, Pages 585: Analysis of a Sea Fog Episode at King George Island, Antarctica Atmosphere doi: 10.3390/atmos10100585 Authors: Jianqiao Chen Bo Han Qinghua Yang Lixin Wei Yindong Zeng Renhao Wu Lin Zhang Zhuoming Ding In this study, a marine fog episode at King George Island off the Antarctic Peninsula from 26–30 January 2017 was investigated using surface observations, upper-air soundings, and re-analysis data as well as the air mass backward...
Atmosphere, Vol. 10, Pages 583: Differentiation of Particulate Matter Sources Based on the Chemical Composition of PM10 in Functional Urban Areas Atmosphere doi: 10.3390/atmos10100583 Authors: Dusan Jandacka Daniela Durcanska Urban air quality is continuing to deteriorate. If we want to do something about this problem, we need to know the cause of the pollution. The big problem, not only in Europe, is the high concentrations of particulate matter (PM) in the urban environment. The...
Atmosphere, Vol. 10, Pages 582: The Baja California Peninsula, a Significant Source of Dust in Northwest Mexico Atmosphere doi: 10.3390/atmos10100582 Authors: Enrique Morales-Acuña Carlos R. Torres Francisco Delgadillo-Hinojosa Jean R. Linero-Cueto Eduardo Santamaría-del-Ángel Rubén Castro Despite their impacts on ecosystems, climate, and human health, atmospheric emissions of mineral dust from deserts have been scarcely studied. This work estimated dust emission flux...
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Behavioral Sciences, Vol. 9, Pages 104: Measuring Experiential Avoidance and Posttraumatic Stress in Families Behavioral Sciences doi: 10.3390/bs9100104 Authors: Meaghan M. Lewis Tamara M. Loverich Experiential avoidance (EA) is receiving attention as an emotion regulation strategy and critical factor in the development and maintenance of posttraumatic stress disorder (PTSD) Evidence suggests that EA explains co-varying relationships among topographically dissimilar problem behaviors....
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Bioengineering, Vol. 6, Pages 89: Development of High Cell Density Cultivation Strategies for Improved Medium Chain Length Polyhydroxyalkanoate Productivity Using Pseudomonas putida LS46 Bioengineering doi: 10.3390/bioengineering6040089 Authors: Warren Blunt Christopher Dartiailh Richard Sparling Daniel J. Gapes David B. Levin Nazim Cicek High cell density (HCD) fed-batch cultures are widely perceived as a requisite for high-productivity polyhydroxyalkanoate (PHA) cultivation...
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Biology, Vol. 8, Pages 73: Effects of Pulsed Electric Field on the Cell Wall and Infection Activity of Rhizoctonia solani Biology doi: 10.3390/biology8040073 Authors: Feng He Pan Xu Xue Yin Qian This paper adopts the Design-Expert software to design an orthogonal experiment with a pulse voltage amplitude of 30 kV, processing time of three minutes, and a pulse width of 45 μs as the center points, in order to study the effects of the pulsed electric field...
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Biomedicines, Vol. 7, Pages 75: Graft Materials and Biologics for Spinal Interbody Fusion Biomedicines doi: 10.3390/biomedicines7040075 Authors: Marissa D’Souza Nicholas A. Macdonald Julian L. Gendreau Pate J. Duddleston Austin Y. Feng Allen L. Ho Spinal fusion is the most widely performed procedure in spine surgery. It is the preferred treatment for a wide variety of pathologies including degenerative disc disease, spondylolisthesis, segmental instability, and deformity....
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Biomolecules, Vol. 9, Pages 537: Associations of SNPs of the ADIPOQ Gene with Serum Adiponectin Levels, Unstable Angina, and Coronary Artery Disease Biomolecules doi: 10.3390/biom9100537 Authors: Smetnev Klimushina Kutsenko Kiseleva Gumanova Kots Skirko Ershova Yarovaya Metelskaya Meshkov Drapkina Adiponectin is encoded by the ADIPOQ gene and participates in the pathogenesis of cardiovascular and metabolic diseases. The goal of the study was...
Biomolecules, Vol. 9, Pages 536: Divergent Roles of CYP26B1 and Endogenous Retinoic Acid in Mouse Fetal Gonads Biomolecules doi: 10.3390/biom9100536 Authors: Laura Bellutti Emilie Abby Sophie Tourpin Sébastien Messiaen Delphine Moison Emilie Trautmann Marie-Justine Guerquin Virginie Rouiller-Fabre René Habert Gabriel Livera In female mammals, germ cells enter meiosis in the fetal ovaries, while in males, meiosis is prevented until postnatal development. Retinoic...
Biomolecules, Vol. 9, Pages 535: MS-Based Approaches Enable the Structural Characterization of Transcription Factor/DNA Response Element Complex Biomolecules doi: 10.3390/biom9100535 Authors: Slavata Chmelík Kavan Filandrová Fiala Rosůlek Mrázek Kukačka Vališ Man Miller McIntyre Fabris Novák The limited information available on the structure of complexes involving transcription factors and cognate DNA response elements represents...
Biomolecules, Vol. 9, Pages 534: Interplay between BMPs and Reactive Oxygen Species in Cell Signaling and Pathology Biomolecules doi: 10.3390/biom9100534 Authors: Cristina Sánchez-de-Diego José Antonio Valer Carolina Pimenta-Lopes José Luis Rosa Francesc Ventura The integration of cell extrinsic and intrinsic signals is required to maintain appropriate cell physiology and homeostasis. Bone morphogenetic proteins (BMPs) are cytokines that belong to the transforming growth...
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Biosensors, Vol. 9, Pages 113: Influence of Graphene Oxide Concentration when Fabricating an Electrochemical Biosensor for DNA Detection Biosensors doi: 10.3390/bios9040113 Authors: Elena A. Chiticaru Luisa Pilan Celina-Maria Damian Eugeniu Vasile Jorge S. Burns Mariana Ioniţă We have investigated the influence exerted by the concentration of graphene oxide (GO) dispersion as a modifier for screen printed carbon electrodes (SPCEs) on the fabrication of an electrochemical...
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Brain Sciences, Vol. 9, Pages 256: The Association between ADHD and Obesity: Intriguing, Progressively More Investigated, but Still Puzzling Brain Sciences doi: 10.3390/brainsci9100256 Authors: Samuele Cortese This narrative review is aimed at presenting the most recent evidence on the association between attention-deficit/hyperactivity disorder (ADHD) and obesity. The review is informed by previous relevant systematic reviews and a search in Pubmed and PsycINFO up to 1 August 2019....
Brain Sciences, Vol. 9, Pages 255: Characteristic of Stimulus Frequency Otoacoustic Emissions: Detection Rate, Musical Training Influence, and Gain Function Brain Sciences doi: 10.3390/brainsci9100255 Authors: Wang Qi Yu Wang Chen Stimulus frequency otoacoustic emission (SFOAE) is an active acoustic signal emitted by the inner ear providing salient information about cochlear function and dysfunction. To provide a basis for laboratory investigation and clinical use, we...
Brain Sciences, Vol. 9, Pages 254: Endocannabinoids and Fear-Related Behavior in Mice Selectively Bred for High or Low Alcohol Preference Brain Sciences doi: 10.3390/brainsci9100254 Authors: Aaron M. Kirchhoff Eric L. Barker Julia A. Chester Alcohol use disorders (AUDs) have a high incidence of co-morbidity with stress-related psychopathologies, such as post-traumatic stress disorder (PTSD). Genetic and pharmacological studies support a prominent role for the endocannabinoid system...
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Cancers, Vol. 11, Pages 1446: In Vitro Characterization of Cisplatin and Pemetrexed Effects in Malignant Pleural Mesothelioma 3D Culture Phenotypes Cancers doi: 10.3390/cancers11101446 Authors: Eleftherios D. Papazoglou Rajesh M. Jagirdar Olympia A. Kouliou Eleanna Pitaraki Chrissi Hatzoglou Konstantinos I. Gourgoulianis Sotirios G. Zarogiannis Malignant pleural mesothelioma (MPM) is an aggressive cancer with poor prognosis. The main treatment for MPM is doublet chemotherapy...
Cancers, Vol. 11, Pages 1447: Evaluation of Intensity- and Contour-Based Deformable Image Registration Accuracy in Pancreatic Cancer Patients Cancers doi: 10.3390/cancers11101447 Authors: Yoshiki Kubota Masahiko Okamoto Yang Li Shintaro Shiba Shohei Okazaki Shuichiro Komatsu Makoto Sakai Nobuteru Kubo Tatsuya Ohno Takashi Nakano We aimed to clarify the accuracy of rigid image registration and deformable image registration (DIR) in carbon-ion radiotherapy (CIRT)...
Cancers, Vol. 11, Pages 1445: NF-κB Dependent Chemokine Signaling in Pancreatic Cancer Cancers doi: 10.3390/cancers11101445 Authors: Geismann Schäfer Gundlach Hauser Egberts Schneider Arlt Pancreatic cancer is one of the carcinomas with the worst prognoses, as shown by its five-year survival rate of 9%. Although there have been new therapeutic innovations, the effectiveness of these therapies is still limited, resulting in pancreatic ductal adenocarcinoma (PDAC)...
Cancers, Vol. 11, Pages 1440: Analysis of Promoter-Associated Chromatin Interactions Reveals Biologically Relevant Candidate Target Genes at Endometrial Cancer Risk Loci Cancers doi: 10.3390/cancers11101440 Authors: Tracy A. O’Mara Amanda B. Spurdle Dylan M. Glubb Endometrial Cancer Association Consortium Endometrial Cancer Association Consortium The identification of target genes at genome-wide association study (GWAS) loci is a major obstacle for GWAS follow-up. To identify...
Cancers, Vol. 11, Pages 1442: A Novel Multi-Target Small Molecule, LCC-09, Inhibits Stemness and Therapy-Resistant Phenotypes of Glioblastoma Cells by Increasing miR-34a and Deregulating the DRD4/Akt/mTOR Signaling Axis Cancers doi: 10.3390/cancers11101442 Authors: Wen Wu Bamodu Wei Lin Yen Chao Mukhopadhyay Hsiao Huang The management of glioblastomas (GBMs) is challenged by the development of therapeutic resistance and early disease recurrence, despite...
Cancers, Vol. 11, Pages 1443: Clinical Routine TERT Promoter Mutational Screening of Follicular Thyroid Tumors of Uncertain Malignant Potential (FT-UMPs): A Useful Predictor of Metastatic Disease Cancers doi: 10.3390/cancers11101443 Authors: Hysek Paulsson Jatta Shabo Stenman Höög Larsson Zedenius Juhlin Mutations of the Telomerase reverse transcriptase (TERT) gene promoter are recurrently found in follicular thyroid carcinoma (FTC) and follicular tumors...
Cancers, Vol. 11, Pages 1441: The Utility of Anatomical Liver Resection in Hepatocellular Carcinoma: Associated with Improved Outcomes or Lack of Supportive Evidence? Cancers doi: 10.3390/cancers11101441 Authors: Michelle Ju Adam C. Yopp Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related deaths worldwide. Surgical resection of HCC remains one of the mainstays of curative therapies and is associated with five-year overall survival rates approaching 60%. Despite...
Cancers, Vol. 11, Pages 1444: Hybrid 18F-FDG-PET/MRI Measurement of Standardized Uptake Value Coupled with Yin Yang 1 Signature in Metastatic Breast Cancer. A Preliminary Study Cancers doi: 10.3390/cancers11101444 Authors: Schiano Franzese Pane Garbino Soricelli Salvatore de Nigris Napoli Purpose: Detection of breast cancer (BC) metastasis at the early stage is important for the assessment of BC progression status. Image analysis represents a valuable tool...
Cancers, Vol. 11, Pages 1436: HDAC3 Activity is Essential for Human Leukemic Cell Growth and the Expression of β-catenin, MYC, and WT1 Cancers doi: 10.3390/cancers11101436 Authors: Mandy Beyer Annette Romanski Al-Hassan M. Mustafa Miriam Pons Iris Büchler Anja Vogel Andrea Pautz Andreas Sellmer Günter Schneider Gesine Bug Oliver H. Krämer Therapy of acute myeloid leukemia (AML) is unsatisfactory. Histone deacetylase inhibitors (HDACi) are active against...
Cancers, Vol. 11, Pages 1439: Splicing Machinery is Dysregulated in Pituitary Neuroendocrine Tumors and is Associated with Aggressiveness Features Cancers doi: 10.3390/cancers11101439 Authors: Vázquez-Borrego Fuentes-Fayos Venegas-Moreno Rivero-Cortés Dios Moreno-Moreno Madrazo-Atutxa Remón Solivera Wildemberg Kasuki López-Fernández Gadelha Gálvez-Moreno Soto-Moreno Gahete Castaño Luque Pituitary neuroendocrine tumors...
Cancers, Vol. 11, Pages 1437: Astrogliosis Releases Pro-Oncogenic Chitinase 3-Like 1 Causing MAPK Signaling in Glioblastoma Cancers doi: 10.3390/cancers11101437 Authors: Julian Wurm Simon P. Behringer Vidhya M. Ravi Kevin Joseph Nicolas Neidert Julian P. Maier Roberto Doria-Medina Marie Follo Daniel Delev Dietmar Pfeifer Jürgen Beck Roman Sankowski Oliver Schnell Dieter H. Heiland Although reactive astrocytes constitute a major component of the...
Cancers, Vol. 11, Pages 1438: An Antibody Specific for the Dog Leukocyte Antigen DR (DLA-DR) and Its Novel Methotrexate Conjugate Inhibit the Growth of Canine B Cell Lymphoma Cancers doi: 10.3390/cancers11101438 Authors: Marta Lisowska Magdalena Milczarek Jarosław Ciekot Justyna Kutkowska Wojciech Hildebrand Andrzej Rapak Arkadiusz Miazek Canine B-cell lymphoma (CBL) is an incurable, spontaneous lymphoid malignancy constituting an accurate animal model for testing novel...
Cancers, Vol. 11, Pages 1435: Personalizing the Prediction of Colorectal Cancer Prognosis by Incorporating Comorbidities and Functional Status into Prognostic Nomograms Cancers doi: 10.3390/cancers11101435 Authors: Daniel Boakye Lina Jansen Martin Schneider Jenny Chang-Claude Michael Hoffmeister Hermann Brenner Despite consistent evidence that comorbidities and functional status (FS) are strong prognostic factors for colorectal cancer (CRC) patients, these important characteristics...
Cancers, Vol. 11, Pages 1434: Data Fusion Techniques for the Integration of Multi-Domain Genomic Data from Uveal Melanoma Cancers doi: 10.3390/cancers11101434 Authors: Max Pfeffer André Uschmajew Adriana Amaro Ulrich Pfeffer Uveal melanoma (UM) is a rare cancer that is well characterized at the molecular level. Two to four classes have been identified by the analyses of gene expression (mRNA, ncRNA), DNA copy number, DNA-methylation and somatic mutations yet no factual integration...
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Cells, Vol. 8, Pages 1154: Subcellular Energetics and Carbon Storage in Chlamydomonas Cells doi: 10.3390/cells8101154 Authors: Burlacot Peltier Li-Beisson Microalgae have emerged as a promising platform for production of carbon- and energy- rich molecules, notably starch and oil. Establishing an economically viable algal biotechnology sector requires a holistic understanding of algal photosynthesis, physiology, cell cycle and metabolism. Starch/oil productivity is a combined...
Cells, Vol. 8, Pages 1153: TGR5 Activation Modulates an Inhibitory Effect on Liver Fibrosis Development Mediated by Anagliptin in Diabetic Rats Cells doi: 10.3390/cells8101153 Authors: Daisuke Kaya Kosuke Kaji Yuki Tsuji Satoko Yamashita Koh Kitagawa Takahiro Ozutsumi Yukihisa Fujinaga Hiroaki Takaya Hideto Kawaratani Kei Moriya Tadashi Namisaki Takemi Akahane Hitoshi Yoshiji Hyperglycemia and hyperinsulinemia activate the proliferative potential of...
Cells, Vol. 8, Pages 1152: Avian MHC Evolution in the Era of Genomics: Phase 1.0 Cells doi: 10.3390/cells8101152 Authors: Emily A. O’Connor Helena Westerdahl Reto Burri Scott V. Edwards Birds are a wonderfully diverse and accessible clade with an exceptional range of ecologies and behaviors, making the study of the avian major histocompatibility complex (MHC) of great interest. In the last 20 years, particularly with the advent of high-throughput sequencing, the avian MHC has...
Cells, Vol. 8, Pages 1151: Individual Copy Number of Ribosomal Genes as a Factor of Mental Retardation and Autism Risk and Severity Cells doi: 10.3390/cells8101151 Authors: Lev Porokhovnik Autism is a complex multifactorial developmental disorder characterized by deficits in communication and restricted interests, often followed by mental retardation. Autism spectrum disorders (ASD) are caused by defects in miscellaneous molecular mechanisms, many of which remain unclear. But a considerable...
Cells, Vol. 8, Pages 1150: Breast Cancer Resistance Protein (BCRP/ABCG2) Inhibits Extra Villous Trophoblast Migration: The Impact of Bacterial and Viral Infection Cells doi: 10.3390/cells8101150 Authors: Phetcharawan Lye Enrrico Bloise Lubna Nadeem Chun Peng William Gibb Tania M. Ortiga-Carvalho Stephen J. Lye Stephen G. Matthews Extravillous trophoblasts (EVT) migration into the decidua is critical for establishing placental perfusion and when dysregulated, may...
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Children, Vol. 6, Pages 105: Social Functioning of Childhood Cancer Survivors after Computerized Cognitive Training: A Randomized Controlled Trial Children doi: 10.3390/children6100105 Authors: Leanne K. Mendoza Jason M. Ashford Victoria W. Willard Kellie N. Clark Karen Martin-Elbahesh Kristina K. Hardy Thomas E. Merchant Sima Jeha Fang Wang Hui Zhang Heather M. Conklin Childhood cancer survivors are at risk for cognitive and social deficits. Previous findings...
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Climate, Vol. 7, Pages 117: Effects of Combined CO2 and O3 Exposures on Net CO2 Assimilation and Biomass Allocation in Seedlings of the Late-Successional Fagus Crenata Climate doi: 10.3390/cli7100117 Authors: Tobita Komatsu Harayama Yazaki Kitaoka Kitao We examined the effects of elevated CO2 and elevated O3 concentrations on net CO2 assimilation and growth of Fagus crenata in a screen-aided free-air concentration-enrichment (FACE) system. Seedlings were exposed...
Climate, Vol. 7, Pages 116: Precipitation Trends over the Indus Basin Climate doi: 10.3390/cli7100116 Authors: Nir Y. Krakauer Tarendra Lakhankar Ghulam H. Dars A large population relies on water input to the Indus basin, yet basinwide precipitation amounts and trends are not well quantified. Gridded precipitation data sets covering different time periods and based on either station observations, satellite remote sensing, or reanalysis were compared with available station observations...
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