BMC Research Notes
- Thrombocytopenia according to antiretroviral drug combinations, viremia and CD4 lymphocytes among HIV-infected patients in Cameroon: a snapshot from the City of YaoundéThrombocytopenia is an abnormal decrease in blood platelets, which can affect the prognosis of people living with HIV (PLHIV). In order to assess the burden of this haematological disorder, we evaluated the fr...
- Capillary blood as an alternative specimen for enumeration of percentages of lymphocyte subsetsCapillary blood has been increasingly used in point-of-care setting for clinical monitoring in immunology and infectious diseases. We explored whether percentages of lymphocyte subsets (T-cells; CD3+, helper T...
Ophthalmic Plastic & Reconstructive Surgery - Published Ahead-of-Print
- Serum Vitamin D Deficiency Is an Independent Risk Factor for Thyroid Eye DiseasePurpose: Thyroid eye disease (TED) is an inflammatory orbitopathy with significant impact on visual function and quality of life. Although studies have shown that patients who are deficient in vitamin D are more likely to develop autoimmune conditions, there are no studies demonstrating a definitive correlation between serum 25-hydroxyvitamin D (25(OH)D) deficiency and an increased risk of TED. Methods: This retrospective case–control stu
- Quality of Life in Thyroid Eye Disease: A Systematic ReviewPurpose: The aim of this systematic review is to provide 1) an understanding of the components of quality of life (QOL) questionnaires and 2) an up-to-date insight of the types of QOL questionnaires available, strengths and limitations based on current literature. Methods: A literature search was conducted from 18 to 21 of February 2019 using 6 major databases: Cochrane Library, Ovid Medline, PubMed, Scopus, Taylor and Francis, and Web of
Ultrasound in Medicine & Biology
- Focused Ultrasound-Mediated Hyperthermia <em>in Vitro</em>: An Experimental Arrangement for Treating Cells under Tissue-Mimicking ConditionsPublication date: Available online 26 September 2019Source: Ultrasound in Medicine & BiologyAuthor(s): Sarah C. Brüningk, Ian Rivens, Petros Mouratidis, Gail ter HaarAbstractAn experimental arrangement that allows in vitro exposure of cells to focused ultrasound-mediated hyperthermia (43°C–55°C) in a tissue-mimicking phantom with biological, acoustic and thermal properties comparable to those of human soft tissue is described. Cells were embedded
- Ultrasound Detection of Abnormal Cerebrovascular Morphology in a Mouse Model of Sickle Cell Disease Based on Wave ReflectionPublication date: Available online 26 September 2019Source: Ultrasound in Medicine & BiologyAuthor(s): Lindsay S. Cahill, Jesper Pilmeyer, Lisa X. Yu, Joe Steinman, Gregory M.T. Hare, Andrea Kassner, Christopher K. Macgowan, John G. SledAbstractSickle cell disease (SCD) is associated with a high risk of stroke, and affected individuals often have focal brain lesions termed silent cerebral infarcts. The mechanisms leading to these types of injurie
- Safety and Efficacy of Ultrasound-Guided High-Intensity Focused Ultrasound Treatment for Uterine Fibroids and AdenomyosisPublication date: Available online 25 September 2019Source: Ultrasound in Medicine & BiologyAuthor(s): Jae-Seong Lee, Gi-Youn Hong, Kye-Hwa Lee, Jung-Hwa Song, Tae-Eung KimAbstractThe objective of this study was to assess the tolerability and efficacy of ultrasound-guided high-intensity focused ultrasound (USgHIFU) ablation using a Haifu JC Focused Ultrasound Tumor Therapeutic System (operating transducer frequency: 0.8 MHz, 300–400 W/cm2) under
- Diagnostic Performance Using Automated Breast Ultrasound System for Breast Cancer in Chinese Women Aged 40 Years or Older: A Comparative StudyPublication date: Available online 25 September 2019Source: Ultrasound in Medicine & BiologyAuthor(s): Li Zhang, Ling-Yun Bao, Yan-Juan Tan, Luo-Qian Zhu, Xiao-Jing Xu, Qing-Qing Zhu, Yan-Na Shan, Jing Zhao, Le-Si Xie, Jan LiuAbstractThe purpose of this study was to investigate the diagnostic performance of the automated breast ultrasound system (ABUS) compared with hand-held ultrasonography (HHUS) and mammography (MG) for breast cancer in women
- Acoustic Histology with Specific Dyes and AntibodiesPublication date: Available online 25 September 2019Source: Ultrasound in Medicine & BiologyAuthor(s): Katsutoshi Miura, Kanna YamashitaAbstractThe present study aims to identify specific staining methods for acoustic histology. We compared attenuation-of-sound (AOS) images from scanning acoustic microscopy (SAM) with light microscopy (LM) images. Ethanol-fixed tissue or cytology samples and formalin-fixed surgical or autopsy specimens were exami
- Corrigendum to ‘Breast elastography early experiences’ [Ultrasound Med Biol 45 (2019) S21-S22]Publication date: Available online 25 September 2019Source: Ultrasound in Medicine & BiologyAuthor(s): Natalie Clements
- Intercellular communication between alveolar epithelial cells and macrophagesPublication date: Available online 26 September 2019Source: Annals of Anatomy - Anatomischer AnzeigerAuthor(s): Anja Beckmann, Alexander Grissmer, Carola Meier, Thomas TschernigAbstractBackgroundThe alveolus in the lung tissue is an extremely vulnerable site. Alveolar macrophages control this micro-environment both in states of health and illnesssuch as acute lung injury and infection. It has been reported in micein vivo that intercellular commun
- Analysis of oral-nasal balance after intensive speech therapy combined with speech bulb in speakers with cleft palate and hypernasalityPublication date: Available online 25 September 2019Source: Journal of Communication DisordersAuthor(s): Gabriela Zuin Ferreira, Tim Bressmann, Jennifer de Cassia Rillo Dutka, Melina Evangelista Whitaker, Gillian de Boer, Viviane Cristina de Castro Marino, Maria Inês Pegoraro-KrookABSTRACTObjectiveTo evaluate the efficacy of the combination of a speech bulb with an intensive speech therapy program in hypernasal participants with cleft palate.Meth
- The nuts and bolts of omics for the clinical allergistPublication date: Available online 25 September 2019Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Yamini V. Virkud, Rachel S. Kelly, Caleb Wood, Jessica A. Lasky-SuAbstractObjectiveOmics, aka multi-omics, is an emerging area of research that is advancing the use of personalized medicine in clinical practice and is therefore relevant for the practicing allergist.Data SourcesWe performed a literature search of a selection of scientific f
- From the Pages of Allergy Watch: December 2019Publication date: Available online 25 September 2019Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): John J. Oppenheimer, Brad E. Chipps, Chitra Dinakar, Stanley M. Fineman
- Le lambeau perforant de l’artère fémorale profonde : une étude anatomique morphométriquePublication date: Available online 25 September 2019Source: Annales de Chirurgie Plastique EsthétiqueAuthor(s): A. Velicanu, F. Boucher, F. Braye, H. Shipkov, S. Brosset, A. MojallalRésuméContexteDans le cadre de la reconstruction mammaire par lambeau libre autologue, le lambeau de l’artère fémorale profonde (PAP) prend une place dans les options thérapeutiques de reconstruction microchirurgicales actuelles. Son prélèvement laissant une rançon ci
JAMA Otolaryngology–Head & Neck Surgery Online First
- Giant Pituitary Adenoma With Inferior Petrosal Sinus, Jugular Foramen, and Hypoglossal Canal ExtensionThis case report describes a patient who presented with morbid obesity, progressive headache, double vision, and blurry vision, and was diagnosed with a pituitary adenoma.
- What Does Head Impulse Testing Really Test?—ReplyIn Reply We thank Drs Curthoys and Halmagyi for their interest in our recently published scoping review. Both have raised some concerns on the validity of our review, which we address herein.
- Dysphagia After Primary TORS With Neck Dissection in Patients With Oropharyngeal CancerThis case series study examines the rates of acute dysphagia and recovery after transoral robotic surgery (TORS) vs radiotherapy and compares swallowing outcomes by primary treatment modality in patients with oropharyngeal cancer.
- Practical Approaches on CD30 Detection and Reporting in Lymphoma DiagnosisWhile our understanding of the biology of CD30 in lymphoma continues to evolve, our need to detect and measure its expression at the protein level remains critically important for diagnosis and patient care. In addition to its diagnostic and prognostic utility, CD30 has emerged as a vehicle for drug targeting through the antibody-drug conjugate brentuximab-vedotin (BV). Given the numerous ways that CD30 is utilized and its emergence as a predicti
- Endometrial Gastric (Gastrointestinal)-type Mucinous Lesions: Report of a Series Illustrating the Spectrum of Benign and Malignant LesionsWith the recent elucidation of gastric-type lesions in the female genital tract (especially in the cervix), occasional cases of endometrial adenocarcinoma displaying gastric (gastrointestinal) differentiation have been reported, but they are currently not recognized as a distinct pathologic entity. We report 9 cases of endometrial mucinous lesions which exhibit gastric (gastrointestinal)-type features by morphology and immunohistochemistry, inclu
- Myoepithelioma-like Hyalinizing Epithelioid Tumors of the Hand With Novel OGT-FOXO3 FusionsMyoepithelial tumors of soft tissue are uncommon neoplasms characterized histologically by spindle to epithelioid cells arranged in cords, nests, and/or reticular pattern with chondromyxoid to hyaline stroma, and genetically by rearrangement involving EWSR1 (among other less common genes) in about half of the cases. The diagnosis often requires immunostaining to confirm myoepithelial differentiation, most importantly the expression of epithelial
- Predictors of Outcome in Mammary Adenoid Cystic Carcinoma: A Multi-Institutional StudyMammary adenoid cystic carcinoma (ACC) is a rare subtype of breast cancer with a favorable prognosis. Here we report on predictors of outcome based on a detailed morphologic review and analysis of 108 mammary ACC. Sixty-four tumors (59.2%) were pure conventional ACC, 23 (21.3%) were pure basaloid ACC. Follow-up was available for 87 patients (median: 51 mo). Eighteen patients (20.7%) developed recurrence: 7 (8%) had local recurrence and 14 (16%) h
- What Does Head Impulse Testing Really Test?To the Editor Walther et al ignore a fundamental rule of neurology: the pattern of the clinical or physiological deficit indicates the site and not the pathology of the lesion. This is the principle of neurological localization—there are textbooks written about it. The head impulse test, just like the caloric test, or the vestibular evoked myogenic potential, or an extensor plantar response can localize a lesion but reveal nothing about its patho
- Evaluation of Hypoglossal Nerve Stimulation Treatment in Obstructive Sleep ApneaThis cohort study examines data from trials on the use of hypoglossal nerve stimulation for treatment of patients with obstructive sleep apnea.
- Cochlear Implant SurgeryThis Patient Page describes the use of cochlear implantation for treatment of hearing loss.
- Imaging for Pediatric Unilateral Sensorineural Hearing Loss—ReplyIn Reply We thank Dr Pross for his reply to our article. The first point raised considers imaging in children with congenital unilateral sensorineural hearing loss (USNHL) without neurological symptoms to rule out retrocochlear malignant abnormalities. We addressed this issue in the discussion section of our review. One glioma was found on magnetic resonance imaging (MRI) but missed on computed tomographic (CT) scan results, in a total of 1504 in
- Imaging for Pediatric Unilateral Sensorineural Hearing LossTo the Editor I read with great interest the report by Ropers et al, “Assessment of the Clinical Benefit of Imaging in Children with Unilateral Sensorineural Hearing Loss: A Systematic Review and Meta-analysis.” The authors present a well-designed review of the literature of obtaining imaging for pediatric patients with unilateral sensorineural hearing loss. The authors reported that they were able to identify a cause of the hearing loss in more
- Traumatic Vidian Nerve InjuryThis case report describes a patient who presented with mild epistaxis and dryness of bilateral nasal cavities and eyes after a traumatic workplace injury and was diagnosed with a vidian nerve injury.
Laryngo-Rhino-Otologie
- Tinnitracks – Erste Ergebnisse einer AnwenderbefragungLaryngo-Rhino-OtolDOI: 10.1055/a-1007-1858 Hintergrund Die Behandlung eines chronischen Tinnitus stellt nach wie vor eine große Herausforderung dar. Vor einigen Jahren wurde das „Tailor-made notched music training“ (TMNMT) als neue Methode vorgeschlagen, bei der die Frequenz eines tonalen Tinnitus aus zu hörender individuell zusammengestellter Musi
The New England Journal of Medicine: Search Results in Interactive Medical Case
- The Element of SurpriseThis interactive case features a 64-year-old woman who presents with symptoms of fatigue, shortness of breath, nausea, weight loss, and loose stools. Test your diagnostic and therapeutic skills at NEJM.org.
British Cochlear Implant Group
- Dimensions of artefacts caused by cochlear and auditory brainstem implants in magnetic resonance imaging.Related ArticlesDimensions of artefacts caused by cochlear and auditory brainstem implants in magnetic resonance imaging. Cochlear Implants Int. 2019 Sep 25;:1-9 Authors: Majdani E, Majdani O, Steffens M, Warnecke A, Lesinski-Schiedat A, Lenarz T, Götz F Abstract Background: The aim of the study was to investigate the extent of MRI artefacts due to the magnet of selected auditory implants. Study desi
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Πέμπτη 26 Σεπτεμβρίου 2019
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