Antibiotics, Vol. 8, Pages 148: Carbapenemase Genes and Multidrug Resistance of Acinetobacter Baumannii: A Cross Sectional Study of Patients with Pneumonia in Southern Vietnam Antibiotics doi: 10.3390/antibiotics8030148 Authors: Cuong Hoang Quoc Thao Nguyen Thi Phuong Hai Nguyen Duc Trung Tran Le Hang Tran Thi Thu Hang Si Nguyen Tuan Lan Phan Trong Background: Acinetobacter baumannii (Ab) is an opportunistic bacterial pathogen found in hospital-acquired infections including...
Antibiotics, Vol. 8, Pages 147: Global Internet Data on the Interest in Antibiotics and Probiotics Generated by Google Trends Antibiotics doi: 10.3390/antibiotics8030147 Authors: Kamiński Mikołaj Łoniewski Igor Marlicz Wojciech Data from the Google search engine enables the assessment of Google users’ interest in a specific topic. We analyzed the world trends in searches associated with the topics “antibiotics” and “probiotics”...
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Antioxidants, Vol. 8, Pages 395: Maltol Improves APAP-Induced Hepatotoxicity by Inhibiting Oxidative Stress and Inflammation Response via NF-κB and PI3K/Akt Signal Pathways Antioxidants doi: 10.3390/antiox8090395 Authors: Zi Wang Weinan Hao Junnan Hu Xiaojie Mi Ye Han Shen Ren Shuang Jiang Yingping Wang Xindian Li Wei Li Maltol, a food-flavoring agent and Maillard reaction product formed during the processing of red ginseng (Panax ginseng, C.A. Meyer), has...
Antioxidants, Vol. 8, Pages 394: Promising Antioxidant and Antimicrobial Food Colourants from Lonicera caerulea L. var. Kamtschatica Antioxidants doi: 10.3390/antiox8090394 Authors: Adriana K. Molina Erika N. Vega Carla Pereira Maria Inês Dias Sandrina A. Heleno Paula Rodrigues Isabel P. Fernandes Maria Filomena Barreiro Marina Kostić Marina Soković João C.M. Barreira Lillian Barros Isabel C.F.R. Ferreira Lonicera caerulea L. (haskap) berries are widely...
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Atmosphere, Vol. 10, Pages 543: Inverting the East Asian Dust Emission Fluxes Using the Ensemble Kalman Smoother and Himawari-8 AODs: A Case Study with WRF-Chem v3.5.1 Atmosphere doi: 10.3390/atmos10090543 Authors: Dai Cheng Goto Schutgens Kikuchi Yoshida Shi Nakajima We present the inversions (back-calculations or optimizations) of dust emissions for a severe winter dust event over East Asia in November 2016. The inversion system based on a fixed-lag ensemble...
Atmosphere, Vol. 10, Pages 544: Differences in Model Performance and Source Sensitivities for Sulfate Aerosol Resulting from Updates of the Aqueous- and Gas-Phase Oxidation Pathways for a Winter Pollution Episode in Tokyo, Japan Atmosphere doi: 10.3390/atmos10090544 Authors: Itahashi Yamaji Chatani Hayami During the Japanese intercomparison study, Japan’s Study for Reference Air Quality Modeling (J-STREAM), it was found that wintertime SO42– concentrations...
Atmosphere, Vol. 10, Pages 542: Spatiotemporal Variations of Meteorological Droughts and the Assessments of Agricultural Drought Risk in a Typical Agricultural Province of China Atmosphere doi: 10.3390/atmos10090542 Authors: Guo Li Wang Long Bai Drought is one of the most common natural disasters on a global scale and has a wide range of socioeconomic impacts. In this study, we analyzed the spatiotemporal variations of meteorological drought in a typical agricultural...
Atmosphere, Vol. 10, Pages 541: Developing Spatially Accurate Rainfall Predictions for the San Francisco Bay Area through Case Studies of Atmospheric River and other Synoptic Events Atmosphere doi: 10.3390/atmos10090541 Authors: Bridger Nguyen Chiao Rainfall patterns in the San Francisco Bay Area (SFBA) are highly influenced by local topography. It has been a forecasting challenge for the main US forecast models. This study investigates the ability of the Weather Research and...
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Behavioral Sciences, Vol. 9, Pages 99: Neuroinflammation and Neuromodulation in Neurological Diseases Behavioral Sciences doi: 10.3390/bs9090099 Authors: Maria de los Angeles Robinson-Agramonte Carlos-Alberto Gonçalves Roberto Farina de Almeida Alina González Quevedo Sandra Chow Luis Velázquez Pérez Amado Díaz de la Fé Patricia Sesterheim Diogo Onofre Gomes de Souza Neuroimmunology is a relatively young science. This discipline has emerged today from the research...
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Beverages, Vol. 5, Pages 58: The Effect of Sonication on Bubble Size and Sensory Perception of Carbonated Water to Improve Quality and Consumer Acceptability Beverages doi: 10.3390/beverages5030058 Authors: Claudia Gonzalez Viejo Damir D. Torrico Frank R. Dunshea Sigfredo Fuentes Bubbles are important for carbonated beverage quality since smaller bubbles contribute to higher acceptability. Therefore, the effects and acceptability of the application of audible sound in carbonated...
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Bioengineering, Vol. 6, Pages 83: Finite Element Driven Design Domain Identification of a Beating Left Ventricular Simulator Bioengineering doi: 10.3390/bioengineering6030083 Authors: Utku Gulbulak Atila Ertas Almost ten percent of the American population have heart diseases. Since the number of available heart donors is not promising, left ventricular assist devices are implemented as bridge therapies. Development of the assist devices benefits from both in-vivo animal and in-vitro...
Bioengineering, Vol. 6, Pages 82: Recent Advances in the Use of Polyhydroyalkanoates in Biomedicine Bioengineering doi: 10.3390/bioengineering6030082 Authors: Alejandra Rodriguez-Contreras Polyhydroxyalkanoates (PHAs), a family of natural biopolyesters, are widely used in many applications, especially in biomedicine. Since they are produced by a variety of microorganisms, they possess special properties that synthetic polyesters do not have. Their biocompatibility, biodegradability,...
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Biomedicines, Vol. 7, Pages 70: Induction of Urokinase Activity by Retinoic Acid in Two Cell Lines of Neuronal Origin Biomedicines doi: 10.3390/biomedicines7030070 Authors: Horvat Madunić Grubar Antica Matulić Retinoic acid is one of the most well-known agents able to induce differentiation in several types of tumours. Unfortunately, most of the tumours are refractive to the differentiation cues. The aim of this investigation was to analyse the effects of prolonged treatment...
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Biomimetics, Vol. 4, Pages 64: Augmented Aircraft Performance with the Use of Morphing Technology for a Turboprop Regional Aircraft Wing Biomimetics doi: 10.3390/biomimetics4030064 Authors: Moens This article presents some application of the morphing technology for aerodynamic performance improvement of turboprop regional aircraft. It summarizes the results obtained in the framework of the Clean Sky 2 AIRGREEN2 program for the development and application of dedicated morphing devices...
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Biomolecules, Vol. 9, Pages 484: Insights into Ergosterol Peroxide’s Trypanocidal Activity Biomolecules doi: 10.3390/biom9090484 Authors: Meza-Menchaca Ramos-Ligonio López-Monteon Vidal Limón Kaluzhskiy Shkel Strushkevich Jiménez-García Agredano Moreno Gallegos-García Suárez-Medellín Trigos Trypanosoma cruzi, which causes Chagas disease, is a significant health threat in many countries and affects millions of people. Given the magnitude of...
Biomolecules, Vol. 9, Pages 485: Long-chain Omega-3 Polyunsaturated Fatty Acids in Natural Ecosystems and the Human Diet: Assumptions and Challenges Biomolecules doi: 10.3390/biom9090485 Authors: Gladyshev Sushchik Over the past three decades, studies of essential biomolecules, long-chain polyunsaturated fatty acids of the omega-3 family (LC-PUFAs), namely eicosapentaenoic acid (20:5n-3, EPA) and docosahexaenoic acid (22:6n-3, DHA), have made considerable progress, resulting in...
Biomolecules, Vol. 9, Pages 483: Identification of miRNAs and Their Target Genes Involved in Cucumber Fruit Expansion Using Small RNA and Degradome Sequencing Biomolecules doi: 10.3390/biom9090483 Authors: Sun Luo Chang Li Zhou Li Zheng Hao Fruit expansion is an essential and very complex biological process. Regulatory roles of microRNAs (miRNAs) and miRNA–mRNA modules in the cucumber fruit expansion are not yet to be investigated. In this work,...
Biomolecules, Vol. 9, Pages 480: Large-Scale Production of Bioactive Terrein by Aspergillus terreus Strain S020 Isolated from the Saudi Coast of the Red Sea Biomolecules doi: 10.3390/biom9090480 Authors: Hani Z. Asfour Zuhier A. Awan Alaa A. Bagalagel Mahmoud A. Elfaky Reda F. A. Abdelhameed Sameh S. Elhady The diversity of symbiotic fungi derived from two marine sponges and sediment collected off Obhur, Jeddah (Saudi Arabia), was investigated in the current study. A total...
Biomolecules, Vol. 9, Pages 482: Quercetin Interrupts the Positive Feedback Loop Between STAT3 and IL-6, Promotes Autophagy, and Reduces ROS, Preventing EBV-Driven B Cell Immortalization Biomolecules doi: 10.3390/biom9090482 Authors: Granato Gilardini Montani Zompetta Santarelli Gonnella Romeo D’Orazi Faggioni Cirone The oncogenic gammaherpesvirus Epstein–Barr virus (EBV) immortalizes in vitro B lymphocytes into lymphoblastoid cell lines (LCLs),...
Biomolecules, Vol. 9, Pages 479: Protective Effects of Sesamin Against UVB-Induced Skin Inflammation and Photodamage In Vitro and In Vivo Biomolecules doi: 10.3390/biom9090479 Authors: Lin Wu Hou Chien Chang Wen Lin Chiang Ultraviolet (UV) exposure has been demonstrated as the most critical factor causing extrinsic skin aging and inflammation. This study explored the protective effects and mechanisms of sesamin against skin photodamage. Sesamin reduced intracellular...
Biomolecules, Vol. 9, Pages 481: Sulfated Glycoaminoglycans and Proteoglycan Syndecan-4 Are Involved in Membrane Fixation of LL-37 and Its Pro-Migratory Effect in Breast Cancer Cells Biomolecules doi: 10.3390/biom9090481 Authors: Chahrazed Habes Günther Weber Caroline Goupille Initially characterized by its antimicrobial activities, LL-37 has also been shown to significantly contribute to tumor development. On breast cancer cell lines, LL-37 increases intracellular calcium via...
Biomolecules, Vol. 9, Pages 477: Carbohydrate-Based Macromolecular Crowding-Induced Stabilization of Proteins: Towards Understanding the Significance of the Size of the Crowder Biomolecules doi: 10.3390/biom9090477 Authors: Sumra Shahid Ikramul Hasan Faizan Ahmad Md. Imtaiyaz Hassan Asimul Islam There are a large number of biomolecules that are accountable for the extremely crowded intracellular environment, which is totally different from the dilute solutions, i.e., the...
Biomolecules, Vol. 9, Pages 478: Assessment of Antioxidant and Cytotoxic Activities of Extracts of Dendrobium crepidatum Biomolecules doi: 10.3390/biom9090478 Authors: Mukti Ram Paudel Mukesh Babu Chand Basant Pant Bijaya Pant Dendrobium crepidatum is an epiphytic orchid found in south Asia including Nepal and China. This orchid species is widely used in traditional Chinese medicine (TCM) for the treatment of cancer, diabetes, cataracts, and fever. The objectives of the present...
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Brain Sciences, Vol. 9, Pages 233: Different Representation Procedures Originated from Multivariate Temporal Pattern Analysis of the Behavioral Response to Pain in Wistar Rats Tested in a Hot-Plate under Morphine Brain Sciences doi: 10.3390/brainsci9090233 Authors: Casarrubea Aiello Santangelo Di Giovanni Crescimanno Temporal pattern analysis is an advanced multivariate technique able to investigate the structure of behavior by unveiling the existence of statistically...
Brain Sciences, Vol. 9, Pages 232: The Use of Neuromodulation for Symptom Management Brain Sciences doi: 10.3390/brainsci9090232 Authors: Farrell Green Aziz Pain and other symptoms of autonomic dysregulation such as hypertension, dyspnoea and bladder instability can lead to intractable suffering. Incorporation of neuromodulation into symptom management, including palliative care treatment protocols, is becoming a viable option scientifically, ethically, and economically in order...
Brain Sciences, Vol. 9, Pages 231: Fetal Brain Abnormality Classification from MRI Images of Different Gestational Age Brain Sciences doi: 10.3390/brainsci9090231 Authors: Attallah Sharkas Gadelkarim Magnetic resonance imaging (MRI) is a common imaging technique used extensively to study human brain activities. Recently, it has been used for scanning the fetal brain. Amongst 1000 pregnant women, 3 of them have fetuses with brain abnormality. Hence, the primary detection and...
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Cancers, Vol. 11, Pages 1357: Kinase Inhibitors and Ovarian Cancer Cancers doi: 10.3390/cancers11091357 Authors: Katopodis Chudasama Wander Sales Kumar Pandhal Anikin Chatterjee Hall Karteris Ovarian cancer is fifth in the rankings of cancer deaths among women, and accounts for more deaths than any other gynecological malignancy. Despite some improvement in overall-(OS) and progression-free survival (PFS) following surgery and first-line chemotherapy,...
Cancers, Vol. 11, Pages 1356: Low Numbers of Vascular Vessels Correlate to Progression in Hormone-Naïve Prostate Carcinomas Undergoing Radical Prostatectomy Cancers doi: 10.3390/cancers11091356 Authors: Smentoch Szade Żaczek Eltze Semjonow Brandt Bednarz-Knoll Vascularization influences tumor development by supporting the nutrition anddissemination of tumor cells. On the other hand, a low number of vascular vessels (VVlow) mayinduce hypoxia, accounting for selection...
Cancers, Vol. 11, Pages 1358: CD123 as a Therapeutic Target in the Treatment of Hematological Malignancies Cancers doi: 10.3390/cancers11091358 Authors: Testa Pelosi Castelli The interleukin-3 receptor alpha chain (IL-3R), more commonly referred to as CD123, is widely overexpressed in various hematological malignancies, including acute myeloid leukemia (AML), B-cell acute lymphoblastic leukemia, hairy cell leukemia, Hodgkin lymphoma and particularly, blastic plasmacytoid dendritic...
Cancers, Vol. 11, Pages 1355: Current Treatment Options for Metastatic Hormone-Sensitive Prostate Cancer. Cancers doi: 10.3390/cancers11091355 Authors: Cattrini Castro Lozano Zanardi Rubagotti Boccardo Olmos The possible treatments options for metastatic hormone-sensitive prostate cancer (mHSPC) have dramatically increased during the last years. The old backbone, which androgen-deprivation therapy (ADT) is the exclusive approach for hormone-naïve patients,...
Cancers, Vol. 11, Pages 1352: Growth Hormone Upregulates Melanocyte-Inducing Transcription Factor Expression and Activity via JAK2-STAT5 and SRC Signaling in GH Receptor-Positive Human Melanoma Cancers doi: 10.3390/cancers11091352 Authors: Reetobrata Basu Prateek Kulkarni Yanrong Qian Christopher Walsh Pranay Arora Emily Davis Silvana Duran-Ortiz Kevin Funk Diego Ibarra Colin Kruse Samuel Mathes Todd McHugh Alison Brittain Darlene E. Berryman Edward...
Cancers, Vol. 11, Pages 1353: CYP2D6 Genotype Predicts Plasma Concentrations of Tamoxifen Metabolites in Ethiopian Breast Cancer Patients Cancers doi: 10.3390/cancers11091353 Authors: Jemal Hussien Ahmed Eyasu Makonnen Alan Fotoohi Abraham Aseffa Rawleigh Howe Eleni Aklillu Tamoxifen displays wide inter-individual variability (IIV) in its pharmacokinetics and treatment outcome. Data on tamoxifen pharmacokinetics and pharmacogenetics from black African breast cancer patient...
Cancers, Vol. 11, Pages 1354: Purine-Metabolising Enzymes and Apoptosis in Cancer Cancers doi: 10.3390/cancers11091354 Authors: Camici Garcia-Gil Pesi Allegrini Tozzi The enzymes of both de novo and salvage pathways for purine nucleotide synthesis are regulated to meet the demand of nucleic acid precursors during proliferation. Among them, the salvage pathway enzymes seem to play the key role in replenishing the purine pool in dividing and tumour cells that require a...
Cancers, Vol. 11, Pages 1351: Early Steps of Mammary Stem Cell Transformation by Exogenous Signals; Effects of Bisphenol Endocrine Disrupting Chemicals and Bone Morphogenetic Proteins Cancers doi: 10.3390/cancers11091351 Authors: Nora Jung Veronique Maguer-Satta Boris Guyot Estrogens are major regulators of the mammary gland development, notably during puberty, via estrogen receptor (ER) activation, leading to the proliferation and differentiation of mammary cells. In addition...
Cancers, Vol. 11, Pages 1350: Human Ovarian Cancer Tissue Exhibits Increase of Mitochondrial Biogenesis and Cristae Remodeling Cancers doi: 10.3390/cancers11091350 Authors: Anna Signorile Domenico De Rasmo Antonella Cormio Clara Musicco Roberta Rossi Francesco Fortarezza Luigi Leonardo Palese Vera Loizzi Leonardo Resta Giovanni Scillitani Ettore Cicinelli Francesca Simonetti Anna Ferretta Silvia Russo Antonio Tufaro Gennaro Cormio Ovarian...
Cancers, Vol. 11, Pages 1349: Estrogens Counteract Platinum-Chemosensitivity by Modifying the Subcellular Localization of MDM4 Cancers doi: 10.3390/cancers11091349 Authors: Rossella Lucà Giorgia di Blasio Daniela Gallo Valentina Monteleone Isabella Manni Laura Fici Marianna Buttarelli Germana Ciolli Marsha Pellegrino Emanuela Teveroni Silvia Maiullari Alessandra Ciucci Alessandro Apollo Francesca Mancini Maria Pia Gentileschi Gian Franco Zannoni...
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Cells, Vol. 8, Pages 1078: Autophagy Stimulation as a Potential Strategy Against Intestinal Fibrosis
Cells, Vol. 8, Pages 1078: Autophagy Stimulation as a Potential Strategy Against Intestinal Fibrosis Cells doi: 10.3390/cells8091078 Authors: Jesus Cosin-Roger Francisco Canet Dulce C. Macias-Ceja Laura Gisbert-Ferrándiz Dolores Ortiz-Masiá Juan V. Esplugues Rafael Alós Francisco Navarro María D. Barrachina Sara Calatayud We recently observed reduced autophagy in Crohn’s disease patients and an anti-inflammatory effect of autophagy stimulation in...
Cells, Vol. 8, Pages 1076: Proteomics of Crystal–Cell Interactions: A Model for Kidney Stone Research Cells doi: 10.3390/cells8091076 Authors: Thongboonkerd Nephrolithiasis/urolithiasis (i.e., kidney stone disease) remains a global public health problem with increasing incidence/prevalence. The most common chemical composition of kidney stones is calcium oxalate that initiates stone formation by crystallization, crystal growth, crystal aggregation, crystal–cell adhesion, and...
Cells, Vol. 8, Pages 1077: Deregulated miR-29b-3p Correlates with Tissue-Specific Activation of Intrinsic Apoptosis in An Animal Model of Amyotrophic Lateral Sclerosis Cells doi: 10.3390/cells8091077 Authors: Klatt Theis Hahn Theiss Matschke Amyotrophic lateral sclerosis (ALS) is one of the most common incurable motor neuron disorders in adults. The majority of all ALS cases occur sporadically (sALS). Symptoms of ALS are caused by a progressive degeneration of motor...
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