In the initial online version of the article, author F.M. Soriani was missing. The original article has been corrected.
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Extraversion is a propensity for optimism, positive emotion, and sociability. Many studies have explored the brain correlates of extraversion, and the results have mainly emphasized the role of reward-related brain regions. However, it is unclear whether imaging studies of the brain’s reward system can show good test–retest reliability. We aim to investigate the neuroanatomical correlates of extraversion and to examine the test–retest reliability of the results. Voxel-based morphometry derived from...
The avian nidopallium caudolaterale, a key region of information integration and processing, is considered to be playing an important role in operant conditioning acquisition and extinction. To reveal sequential neural information processing in the process, neural signals of different experimental periods (induction, acquisition, and extinction) from the nidopallium caudolaterale of pigeons were acquired and the energy of the specific frequency band was analyzed from the light stimulation input to...
As one of the major causes of mortality and disability worldwide, ischemic stroke has never been received enough attention. Following ischemia/reperfusion injury, long non-coding RNAs have been extensively found to be involved into inflammatory responses, microvascular endothelial cell death, and angiogenesis in the brain. The small nucleolar RNA host gene 12 was found to be significantly increased following transient middle cerebral artery occlusion. However, the effect and underlying mechanism...
Orexins are neuromodulatory peptides of the lateral hypothalamus which regulate homeostatic mechanisms including sleep-wakefulness cycles. Orexinergic actions stabilize wakefulness by acting on the nuclei of the reticular activating system, including the pedunculopontine nucleus. Orexin application to pedunculopontine neurons produces a noisy tonic inward current and an increase in the frequency and amplitudes of excitatory postsynaptic currents. In the present project, we investigated orexinergic...
Cognitive dysfunction accompanied by neurofibromatosis type 1 is one of the significant characteristics of this neurocutaneous disorder and has a serious impact on patients’ quality of life. Although studies on cognitive function in children with neurofibromatosis type 1 have revealed that attentional impairment is a key deficit in these patients, few studies have examined their neuropsychological profile, especially whether the attentional function is also abnormal and specific in adult patients...
The visual crowding makes it difficult to identify the patterns in peripheral vision, but the neural mechanism for this phenomenon is still unclear because of different opinions. To study the separation effect of early visual cortex V1 under different crowding conditions, single-pulse transcranial magnetic stimulation (TMS) is applied within the right V1. The experimental design includes two factors: TMS intensity (10%, 65%, and 90% of the phosphene threshold) and crowding conditions (high and low)....
The hypnotic effect of propofol involves inhibition of GABAergic neurons in the lateral hypothalamus
Propofol is widely used for induction and maintenance of anaesthesia, which causes a rapid loss of consciousness. So far the mechanisms underlying the effect of propofol are still largely unknown. Here, we found that microinjection of propofol in the lateral hypothalamus caused a significant decrease in wakefulness and an increase in the amount of non-rapid eye movement sleep and rapid eye movement sleep. Application of propofol in the lateral hypothalamus affected the electroencephalogram power...
Neurones in the primary visual cortex (V1) are classified into simple and complex types. Simple cells are phase-sensitive, that is, they modulate their responses according to the position and brightness polarity of edges in their receptive fields. Complex cells are phase invariant, that is, they respond to edges in their receptive fields regardless of location or brightness polarity. Simple and complex cells are quantified by the degree of sensitivity to the spatial phases of drifting sinusoidal...
To investigate whether perceptual processes involved in early stages of face processing are influenced by depressive disorder, the face detection and configural analysis were assessed by recording the N170 component elicited by faces and objects (tables) presented under upright and inverted conditions. The N170 component elicited at occipital–temporal sites by faces was larger and peaked later than that elicited by tables, and inverted faces significantly enhanced and delayed the N170. The N170 in...
CA1 hippocampal neurons are sensitive to ischemia. The erythropoietin-producing hepatocellular carcinoma (Eph) receptors are a cell-cell contact signaling pathway for regulating neuron function and death. However, the mechanisms of EphA receptor in neuron death after ischemia remain unclear. In this study, we present evidence that outwardly rectifying chloride channels reside in CA1 hippocampal neurons. EphA4 receptor increased chloride channel currents. Moreover, the EphA4 receptor no longer had...
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Related ArticlesThe Chiari I malformation. J Neurosurg Pediatr. 2019 Sep 01;24(3):217-226 Authors: McClugage SG, Oakes WJ Abstract As with many pathologies, the course of our understanding of the Chiari I malformation (CIM) has developed extensively over time. The early descriptions of the Chiari malformations by Hans Chiari in 1891 opened the door for future classification and research on this topic. However, even over a long timeframe, our understanding...
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