Related ArticlesIsolated hypoglossal nerve palsy due to a jugular foramen schwannoma. Ideggyogy Sz. 2019 Jul 30;72(7-8):282-284 Authors: Öztop-Çakmak Ö, Vanli-Yavuz E, Aygün S, Bastan B, Egemen E, Solaroğlu I, Gursoy-Ozdemir Y Abstract Introduction - Although the involvement of the hypoglossal nerve together with other cranial nerves is common in several pathological conditions of the brain, particularly the brainstem, isolated hypoglossal nerve palsy...
Related ArticlesBiomarkers of Targeted Therapy and Immuno-Oncology in Cancers Metastatic to the Breast. Appl Immunohistochem Mol Morphol. 2019 Sep 11;: Authors: Vranic S, Senarathne W, Stafford P, Poorman K, Pockaj BA, Gatalica Z Abstract The breast is a rare site for metastases, and their molecular characteristics have not been studied yet. Intrinsic molecular genetics, cancer characteristics, and breast tissue immune responses in diverse metastases...
Related ArticlesPediatric gastroenteropancreatic neuroendocrine tumor: A case report and review of the literature. Medicine (Baltimore). 2019 Sep;98(37):e17154 Authors: Gaiani F, de'Angelis N, Minelli R, Kayali S, Carra MC, de'Angelis GL Abstract INTRODUCTION: Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are a heterogeneous group of epithelial neoplasms originating from the diffuse neuroendocrine cell system of the gastrointestinal tract and...
Related ArticlesPulmonary carcinosarcoma: analysis from the Surveillance, Epidemiology and End Results database. Interact Cardiovasc Thorac Surg. 2019 Sep 13;: Authors: Sun L, Dai J, Wang X, Jiang G, Gonzalez-Rivas D, Song J, Zhang P Abstract OBJECTIVES: Pulmonary carcinosarcoma (PCS) is a rare neoplasm. This study explored the clinicopathological characteristics and survival outcomes of PCS. METHODS: The Surveillance, Epidemiology and End Results...
Related ArticlesNeuroendocrine carcinoma of the endometrium: Disease course, treatment, and outcomes. Gynecol Oncol. 2019 Sep 10;: Authors: Schlechtweg K, Chen L, St Clair CM, Tergas AI, Khoury-Collado F, Hou JY, Melamed A, Neugut AI, Hershman DL, Wright JD Abstract OBJECTIVE: Neuroendocrine carcinoma of the endometrium (NECE) is a rare malignancy. We examined the natural history and outcomes of women with NECE compared to patients with poorly differentiated...
Related ArticlesCombination Treatment With Sorafenib and Everolimus Regresses a Doxorubicin-resistant Osteosarcoma in a PDOX Mouse Model. Anticancer Res. 2019 Sep;39(9):4781-4786 Authors: Higuchi T, Sugisawa N, Miyake K, Oshiro H, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Kline Z, Belt P, Chawla SP, Bouvet M, Singh SR, Tsuchiya H, Hoffman RM Abstract BACKGROUND/AIM: Osteosarcoma is a rare but recalcitrant type of bone cancer. To discover an...
Related ArticlesMetastatic Bilateral Strumal Carcinoid: A Case Report and Review of the Literature. Anticancer Res. 2019 Sep;39(9):5053-5056 Authors: Borghese M, Razzore P, Ferrero A, Daniele L, Mariani LL, Sgro LG, DE Rosa G, Biglia N Abstract Primary ovarian carcinoids are very rare tumors that belong to the germ cell family of ovarian malignancies. They account for less than 1% of all carcinoid tumors and for less than 0.1% of all ovarian neoplasms....
Related ArticlesAcute reversible left ventricular systolic dysfunction associated with 5-fluorouracil therapy: a rare and increasingly recognised cardiotoxicity of a commonly used drug. BMJ Case Rep. 2019 Sep 12;12(9): Authors: Mishra T, Shokr M, Ahmed A, Afonso L Abstract 5-Fluorouracil (5-FU) is the third most common chemotherapeutic agent for treating solid cancers and the second most common to cause cardiotoxicity. We present a rare case of acute...
Related Articles[Masquerade lacrimal duct stenosis: prevalence of lacrimal sac tumors]. Ophthalmologe. 2019 Sep 13;: Authors: Mihailovic N, Steenken J, Elges S, Merté RL, Grenzebach U, Eter N, Alnawaiseh M Abstract BACKGROUND: Tumors of the lacrimal sac are a rare entity. Malignancies are often associated with a high mortality rate. Lacrimal sac tumors often present as lacrimal duct stenosis with dacryocystitis and are often only diagnosed after an intraoperative...
Related ArticlesVanadium(V) tris-3,5-di-tert-butylcatecholato complex: Links between speciation and anti-proliferative activity in human pancreatic cancer cells. J Inorg Biochem. 2019 Sep 03;201:110815 Authors: Griffin E, Levina A, Lay PA Abstract Vanadium complexes are intensively tested for anti-cancer activities, particularly for the novel treatment protocols involving injections of cytotoxic compounds directly into the tumor. This approach is increasingly...
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Abstract Anti‐PD‐1/PD‐L1 therapy, which is one of the most promising cancer therapies, is licensed for treating various tumors. PD‐L1, which is expressed on the surface of cancer cells, leads to the inhibition of T lymphocyte activation and immune evasion if it binds to the receptor PD‐1 on cytotoxic T lymphocytes. Anti‐PD‐1/PD‐L1 antibodies inhibit interactions between PD‐1 and PD‐L1 to restore antitumor immunity. Although certain patients achieve effective responses to anti‐PD‐1/PD‐L1 therapy,...
Abstract Despite the availability of various diagnostic procedures, a tissue biopsy is still indispensable for the routine diagnosis of lung cancer. However, inaccurate diagnoses can occur, leading to inefficient cancer management. In this context, utilization of circulating microRNAs (miRNAs) may serve as diagnostic tools as liquid biopsies, and as biomarkers to better understand the molecular mechanisms involved in the progression of cancer. In this context, we identified miR‐590‐5p as a potential...
Abstract Aflibercept plus 5‐fluorouracil/levofolinate/irinotecan is a second‐line treatment for metastatic colorectal cancer. This ancillary exploratory analysis of data in Japanese people was aimed at exploring the relationship between a set of potential prognostic biomarkers and efficacy endpoints following aflibercept plus 5‐fluorouracil/levofolinate/irinotecan therapy. Sixty‐two patients with metastatic colorectal cancer received aflibercept (4 mg/kg) plus 5‐fluorouracil/levofolinate/irinotecan...
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Publication date: 15 January 2020Source: Talanta, Volume 207Author(s): Jacopo La Nasa, Federica Nardella, Francesca Modugno, Maria Perla Colombini, Erika Ribechini, Ilaria DeganoAbstractA fast non‐destructive approach based on the use of portable selected ion flow tube-mass spectrometry (SIFT-MS) was used for the first time to characterize organic materials in archaeological artifacts. The high sensitivity, specificity and selectivity SIFT soft chemical ionization mass spectrometry enabled us to...
Publication date: 15 January 2020Source: Talanta, Volume 207Author(s): Yuanyu Huang, Quanqing Zhang, Yingchao Liu, Biyun Jiang, Juanjuan Xie, Tianqi Gong, Bin Jia, Xiaohui Liu, Jun Yao, Weiqian Cao, Huali Shen, Pengyuan YangAbstractThe emitter clogging is the most common hardware failure of nano-electrospray ionization, to improve the durability and electrospray stability of fused silica emitters, we demonstrate a means of fabricating nano-electrospray emitters with controllable aperture size and...
Publication date: 15 January 2020Source: Talanta, Volume 207Author(s): J. Jiménez-López, E.J. Llorent-Martínez, P. Ortega-Barrales, A. Ruiz-MedinaAbstractGlyphosate (Gly) is the most widely used herbicide at the moment. It presents a broad spectrum of action, hence its use for many different crops. Regulatory agencies have constantly mentioned the low hazard potential of Gly to mammals. However, the International Agency for Research on Cancer concluded in 2015 that glyphosate is “probably carcinogenic...
Publication date: 15 January 2020Source: Talanta, Volume 207Author(s): Vanesa Muñoz, María Carolina Talio, Raúl Gil, Liliana Patricia FernándezAbstractNonsteroidal anti-inflammatory agents (NSAIDs) are a group of pharmaceuticals considered one of the most popular drugs used in clinical practice applied to the treatment of acute and chronic conditions. Some pharmaceuticals products are excreted reaching the environment and altering the balance of ecosystems. This work proposes a new fluorimetric flow...
Publication date: 15 January 2020Source: Talanta, Volume 207Author(s): Fang Li, Lei Guo, Yuting Hu, Zimu Li, Jiachang Liu, Jianbo He, Hua CuiAbstractAcute myocardial infarction (AMI) causes significant mortality and morbidity. The determination of multiple AMI biomarkers is very important for the timely diagnosis of AMI. In this work, simultaneous determination of three AMI biomarkers were achieved by virtue of a three-dimensional (3D) microfluidic paper-analytical device (μPAD) with temporally resolved...
Publication date: 15 January 2020Source: Talanta, Volume 207Author(s): Man He, Shaowei Su, Beibei Chen, Bin HuAbstractHerein, polyaniline functionalized magnetic nanoparticles (MNPs) were prepared and investigated as the adsorbents for the separation and enrichment of inorganic selenium and tellurium species. The prepared Fe3O4@SiO2@polyaniline (PANI) MNPs presents selective adsorption performance for SeIV and TeIV, along with fast adsorption and desorption dynamics. Based on it, a method combining...
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Related ArticlesUnilateral Sensorineural Hearing Loss Presenting With Bilateral Temporal Bone Lesions. Otol Neurotol. 2018 03;39(3):e214-e215 Authors: Sakai M, Wick CC, Kutz JW PMID: 29342040 [PubMed - indexed for MEDLINE]
Related ArticlesDirection-fixed and Direction-changing Positional Nystagmus in Ramsay Hunt Syndrome. Otol Neurotol. 2018 03;39(3):e209-e213 Authors: Kim CH, Choi JW, Han KJ, Lee YS, Shin JE Abstract OBJECTIVES: To investigate the incidence of positional nystagmus (PN) using a head-roll test in patients with Ramsay Hunt syndrome with vertigo (RHS_V) and discuss possible mechanisms. STUDY DESIGN: Retrospective study. SETTING: Tertiary...
Related ArticlesUtilizing T-cell Activation Signals 1, 2, and 3 for Tumor-infiltrating Lymphocytes (TIL) Expansion: The Advantage Over the Sole Use of Interleukin-2 in Cutaneous and Uveal Melanoma. J Immunother. 2018 Nov/Dec;41(9):399-405 Authors: Tavera RJ, Forget MA, Kim YU, Sakellariou-Thompson D, Creasy CA, Bhatta A, Fulbright OJ, Ramachandran R, Thorsen ST, Flores E, Wahl A, Gonzalez AM, Toth C, Wardell S, Mansaray R, Radvanyi LG, Gombos DS, Patel SP, Hwu P, Amaria...
Related ArticlesPrevalence and Epidemiologic Profile of Oral Infection with Alpha, Beta, and Gamma Papillomaviruses in an Asian Chinese Population. J Infect Dis. 2018 07 02;218(3):388-397 Authors: Wong MCS, Vlantis AC, Liang M, Wong PY, Ho WCS, Boon SS, Sze RKH, Leung C, Chan PKS, Chen Z Abstract Background: Knowledge of the prevalence of and risk factors for oral human papillomavirus (HPV) infection, especially cutaneous types, is limited. ...
Related ArticlesDecellularization and genipin crosslinking of amniotic membrane suitable for tissue engineering applications. J Biomater Sci Polym Ed. 2018 12;29(17):2051-2067 Authors: Gobinathan S, Zainol SS, Azizi SF, Iman NM, Muniandy R, Hasmad HN, Yusof MRB, Husain S, Abd Aziz H, Lokanathan Y Abstract Amniotic membrane has the potential to be used as scaffold in various tissue engineering applications. However, increasing its biostability at the...
Related ArticlesEffect of Stress Ball Use or Hand-holding on Anxiety During Skin Cancer Excision: A Randomized Clinical Trial. JAMA Dermatol. 2018 09 01;154(9):1045-1049 Authors: Yanes AF, Weil A, Furlan KC, Poon E, Alam M Abstract Importance: Patients undergoing skin surgery under local anesthesia can experience anxiety. Adjuvant intraoperative anxiety reduction methods may help. Objectives: To assess whether hand-holding or holding a stress...
Related ArticlesOropharyngeal histoplasmosis in an HIV-negative patient. Ear Nose Throat J. 2018 Oct-Nov;97(10-11):E49-E50 Authors: Alwani M, Wannemuehler TJ, Summerlin DJ, Couch ME PMID: 30481856 [PubMed - indexed for MEDLINE]
Related ArticlesImpact of HPV Infection on the Immune System in Oropharyngeal and Non-Oropharyngeal Squamous Cell Carcinoma: A Systematic Review. Cells. 2019 Sep 10;8(9): Authors: Lechien JR, Seminerio I, Descamps G, Mat Q, Mouawad F, Hans S, Julieron M, Dequanter D, Vanderhaegen T, Journe F, Saussez S Abstract OBJECTIVES: To review the current knowledge regarding the involvement of human papilloma virus (HPV) infection and the immune system in the development...
Related ArticlesAn Anatomic Variant of the Ansa Cervicalis Precluding Its Use as a Donor Nerve. Ann Otol Rhinol Laryngol. 2019 Sep 11;:3489419875975 Authors: Zhu A, Mohan S, Richmon JD, Jowett N Abstract BACKGROUND: The ansa cervicalis is useful for cranial nerve repair, and may be harvested without apparent morbidity. Herein we report an unusual and surgically relevant anatomic variant of the ansa cervicalis. METHODS: An adult male with left...
Related ArticlesA Practical Mathematic Method to Predict and Manage Hypocalcemia After Parathyroidectomy and Thyroidectomy. Ann Otol Rhinol Laryngol. 2019 Sep 11;:3489419876291 Authors: Liu C, Tang L, Goel P, Chambers T, Kokot N, Sinha U, Maceri D Abstract OBJECTIVE: Prediction and early intervention for hypocalcemia following parathyroidectomy and total thyroidectomy can decrease hospital cost and prevent severe hypocalcemia-related complications. This...
Related ArticlesPitfalls of delaying the diagnosis of hereditary haemorrhagic telangiectasia. J Int Med Res. 2019 Sep 11;:300060519860971 Authors: Major T, Csobay-Novák C, Gindele R, Szabó Z, Bora L, Jóni N, Rácz T, Karosi T, Bereczky Z PMID: 31510822 [PubMed - as supplied by publisher]
Related ArticlesCharacterization and radiosensitivity of HPV-related oropharyngeal squamous cell carcinoma patient-derived xenografts. Acta Oncol. 2019 Sep 11;:1-6 Authors: Lilja-Fischer JK, Ulhøi BP, Alsner J, Stougaard M, Thomsen MS, Busk M, Lassen P, Steiniche T, Nielsen VE, Overgaard J Abstract Background: Oropharyngeal squamous cell carcinomas (OPSCC) are rising rapidly in incidence due to Human Papillomavirus (HPV) and/or tobacco smoking. Prognosis...
Related ArticlesCase of nasopharyngeal teratoma: challenges in the management. BMJ Case Rep. 2019 Sep 11;12(9): Authors: Mishra N, Mandelia A, Naranje K, Singh A Abstract Teratomas are tumour with tissue or organ components resembling normal derivatives of more than one germ layer. The most common site of congenital teratoma is sacrococcygeal region. Teratomas in head and neck region are rarer. We report a 4-day-old male baby who presented with nasopharyngeal...
Related ArticlesQuincke's disease. BMJ Case Rep. 2019 Sep 11;12(9): Authors: Chandran A, Sakthivel P, Chirom AS PMID: 31511276 [PubMed - in process]
Related ArticlesDrug-induced sleep endoscopy compared with systematic adenotonsillectomy in the management of obstructive sleep apnoea in children: a systematic review and meta-analysis protocol. BMJ Open. 2019 Sep 11;9(9):e028242 Authors: Prévost AS, Hylands M, Gervais M, Praud JP, Battista MC, Déziel-Malouin S, Lachance M, Lamontagne F Abstract INTRODUCTION: Obstructive sleep apnoea affects up to 6% of children worldwide. Although current guidelines...
Related ArticlesMachine learning analysis of DNA methylation profiles distinguishes primary lung squamous cell carcinomas from head and neck metastases. Sci Transl Med. 2019 Sep 11;11(509): Authors: Jurmeister P, Bockmayr M, Seegerer P, Bockmayr T, Treue D, Montavon G, Vollbrecht C, Arnold A, Teichmann D, Bressem K, Schüller U, von Laffert M, Müller KR, Capper D, Klauschen F Abstract Head and neck squamous cell carcinoma (HNSC) patients are at risk of...
Related ArticlesLymph node ratio (LNR) as a complementary staging system to TNM staging in salivary gland cancer. Eur Arch Otorhinolaryngol. 2019 Sep 11;: Authors: Lei BW, Hu JQ, Yu PC, Wang YL, Wei WJ, Zhu J, Shi X, Qu N, Lu ZW, Ji QH Abstract PURPOSE: The role of lymph node ratio (LNR, ratio of metastatic to examined nodes) in the staging of multiple human malignancies has been reported. We aim to evaluate its value in salivary gland cancer (SGC)....
Related ArticlesTexture analysis of pretreatment [18F]FDG PET/CT for the prognostic prediction of locally advanced salivary gland carcinoma treated with interstitial brachytherapy. EJNMMI Res. 2019 Sep 11;9(1):89 Authors: Wu WJ, Li ZY, Dong S, Liu SM, Zheng L, Huang MW, Zhang JG Abstract BACKGROUND: The aim of this study was to evaluate the prognostic value of positron emission tomography (PET) parameters and the PET texture features of fluorine 18-fluorodeoxyglucose...
Related ArticlesComparing the Utility and Surgical Outcomes of Harmonic Focus Ultrasonic Scalpel with Ligasure Small Jaw Bipolar Device in Thyroidectomies: A Prospective Randomized Controlled Trial. Ann Surg Oncol. 2019 Sep 11;: Authors: Lee SH, Nguyen TK, Ong WS, Haaland B, Tay GC, Tan NC, Tan HK, Ng JCF, Iyer NG Abstract BACKGROUND: Ultrasonic or bipolar radiofrequency energy devices are routinely used for dissection and hemostasis during thyroidectomy....
Related ArticlesCutaneous manifestation of IgG4-related disease mimicking dermatitis artefacta. Australas J Dermatol. 2019 Sep 11;: Authors: Ashoka Menon V, Tong E, Slape DRL, Phan TA, Chan RC Abstract Dermatitis artefacta is a self-inflicted cutaneous disease presenting as sharply delineated ulcers, usually in accessible sites such as the head and neck. IgG4-related disease (IgG4-RD) is a recently recognised immune-mediated condition causing a fibroinflammatory...
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