Related ArticlesCutaneous manifestation of IgG4-related disease mimicking dermatitis artefacta. Australas J Dermatol. 2019 Sep 11;: Authors: Ashoka Menon V, Tong E, Slape DRL, Phan TA, Chan RC Abstract Dermatitis artefacta is a self-inflicted cutaneous disease presenting as sharply delineated ulcers, usually in accessible sites such as the head and neck. IgG4-related disease (IgG4-RD) is a recently recognised immune-mediated condition causing a fibroinflammatory...
Fri Sep 13, 2019 13:03
Related ArticlesNovel findings in immunopathophysiology of chronic rhinosinusitis and their role in a model of precision medicine. Allergy. 2019 Sep 11;: Authors: Xu X, Ong YK, Wang Y Abstract Our understanding of the pathophysiology of chronic rhinosinusitis (CRS) is continuously evolving. The traditional description of CRS in terms of two phenotypes based on the presence or absence of nasal polyps belies the underlying intricate immunopathophysiological...
Fri Sep 13, 2019 13:03
Related ArticlesRecurrent Laryngeal Nerve Transection in Mice Results in Translational Upper Airway Dysfunction. J Comp Neurol. 2019 Sep 11;: Authors: Haney MM, Hamad A, Woldu HG, Ciucci M, Nichols N, Bunyak F, Lever TE Abstract The recurrent laryngeal nerve (RLN) is responsible for normal vocal fold (VF) movement, and is at risk for iatrogenic injury during anterior neck surgical procedures in human patients. Injury, resulting in VF paralysis, may contribute...
Fri Sep 13, 2019 13:03
Related ArticlesExpression of the long noncoding RNA RP11-169D4.1-001 in Hypopharyngeal Squamous cell carcinoma tissue and its clinical significance. J Clin Lab Anal. 2019 Sep 11;:e23019 Authors: Shen Z, Wu L, Hao W, Li Q, Zhou C Abstract BACKGROUND: Increased research efforts have demonstrated that lncRNAs are associated with multiple head and neck tumors and play important roles in cancer. We previously found that RP11-169D4.1-001 plays a tumor-suppressive...
Fri Sep 13, 2019 13:03
Related ArticlesHGF/MET pathway aberrations as diagnostic, prognostic, and predictive biomarkers in human cancers. Crit Rev Clin Lab Sci. 2019 Sep 12;:1-34 Authors: Moosavi F, Giovannetti E, Saso L, Firuzi O Abstract Cancer is a major cause of death worldwide. MET tyrosine kinase receptor [MET, c-MET, hepatocyte growth factor (HGF) receptor] pathway activation is associated with the appearance of several hallmarks of cancer. The HGF/MET pathway has emerged...
Fri Sep 13, 2019 14:32
Related ArticlesIs auditory brainstem response a prognostic factor in patients with sudden sensorineural hearing loss? Acta Otolaryngol. 2019 Sep 12;:1-6 Authors: Heo HJ, Choi CH, Hong SH, Kang S, Kim MG, Chang YS Abstract Background: Serum thyroid hormone levels are closely related to the normal functioning of the cochlea. However, the relationship between initial auditory brainstem response (ABR) results and levels of thyroid hormone remained unclear...
Fri Sep 13, 2019 14:32
Related ArticlesDo not de-escalate oncology care in oropharyngeal cancer routinely. Head Neck. 2019 Sep 12;: Authors: Szturz P, Vermorken JB PMID: 31512784 [PubMed - as supplied by publisher]
Fri Sep 13, 2019 14:32
Related ArticlesReply to "Do not de-escalate oncology care in oropharyngeal cancer routinely". Head Neck. 2019 Sep 12;: Authors: Ilmarinen T, Keski-Säntti HT, Markkanen-Leppänen ML, Haapaniemi A, Tapiovaara L, Atula T, Bäck L PMID: 31512788 [PubMed - as supplied by publisher]
Fri Sep 13, 2019 14:32
Related ArticlesFree flap salvage from venous thrombosis by creation of a venocutaneous fistula: Case report and review of the literature. Head Neck. 2019 Sep 12;: Authors: Sethia R, Allarakhia Z, Puram S, Kang S, Ozer E, Agrawal A, Carrau R, Rocco J, Old M Abstract BACKGROUND: Venous congestion is the most frequently reported complication of free flap tissue transfer in head and neck patient with cancer. Numerous methods are utilized and prompt correction...
Fri Sep 13, 2019 14:32
Related ArticlesElevated incidence of head and neck cancer in solid organ transplant recipients. Head Neck. 2019 Sep 12;: Authors: Mowery AJ, Conlin MJ, Clayburgh DR Abstract BACKGROUND: Solid organ transplant recipients are known to be at an increased risk of cancer development, but research on head and neck cancer in transplant recipients has been limited and prior risk assessments may not be accurate. METHODS: A retrospective review using...
Fri Sep 13, 2019 14:32
Related ArticlesEvaluation of oncologic outcomes in head and neck cancer patients ≥80 years old based on adherence to NCCN guideline for postoperative adjuvant treatment. Head Neck. 2019 Sep 12;: Authors: Roden D, Daniels K, Metkus J, Goldman R, Walsh A, Johnson J, Hamilton J, Keane W, Chapman A, Bar-Ad V, Sweeny L, Curry J, Cognetti D, Luginbuhl A Abstract BACKGROUND: There is a paucity of literature characterizing outcomes in older adult patients with...
Fri Sep 13, 2019 14:32
Related ArticlesDelivering Timely Head and Neck Cancer Care to an Underserved Urban Population-Better Late Than Never, but Never Late Is Better. JAMA Otolaryngol Head Neck Surg. 2019 Sep 12;: Authors: Graboyes EM, Hughes-Halbert C PMID: 31513251 [PubMed - as supplied by publisher]
Fri Sep 13, 2019 14:32
Related ArticlesAssociation of Delayed Time to Treatment Initiation With Overall Survival and Recurrence Among Patients With Head and Neck Squamous Cell Carcinoma in an Underserved Urban Population. JAMA Otolaryngol Head Neck Surg. 2019 Sep 12;: Authors: Liao DZ, Schlecht NF, Rosenblatt G, Kinkhabwala CM, Leonard JA, Ference RS, Prystowsky MB, Ow TJ, Schiff BA, Smith RV, Mehta V Abstract Importance: Delay in time to treatment initiation (TTI) can alter...
Fri Sep 13, 2019 14:32
Related ArticlesAssociation of Obstructive Sleep Apnea With the Risk of Affective Disorders. JAMA Otolaryngol Head Neck Surg. 2019 Sep 12;: Authors: Kim JY, Ko I, Kim DK Abstract Importance: Obstructive sleep apnea (OSA) is a common subtype of sleep breathing disorder; however, the association between OSA and the psychological health of affected individuals has not been fully evaluated. Objective: To investigate the association between OSA and...
Fri Sep 13, 2019 14:32
Related ArticlesA genetic variant within MDM4 3'UTR miRNA binding site is associated with HPV16-positive tumors and survival of oropharyngeal cancer. Mol Carcinog. 2019 Sep 12;: Authors: Zhang Y, Sturgis EM, Wei P, Liu H, Wang Z, Ma Y, Liu C, Gu KJ, Wei Q, Li G Abstract As mouse double minute 4 (MDM4) and HPV16 E6 oncoproteins play important roles in inhibition of p53 activity, a functional polymorphism (rs4245739) in the 3' untranslated regions of MDM4...
Fri Sep 13, 2019 14:32
Related ArticlesRespiratory-Related Displacement of the Trachea in Obstructive Sleep Apnea. J Appl Physiol (1985). 2019 Sep 12;: Authors: Tong J, Jugé L, Burke PGR, Knapman F, Eckert DJ, Bilston LE, Amatoury J Abstract Tracheal displacement is thought to be the primary mechanism by which changes in lung volume influence upper airway patency. Caudal tracheal displacement during inspiration may help preserve the integrity of the upper airway in response...
Fri Sep 13, 2019 14:32
Related ArticlesAcellular fish skin matrix on thin-skin graft donor sites: a preliminary study. J Wound Care. 2019 Sep 02;28(9):624-628 Authors: Badois N, Bauër P, Cheron M, Hoffmann C, Nicodeme M, Choussy O, Lesnik M, Poitrine FC, Fromantin I Abstract OBJECTIVE: Surgery for head and neck cancer often requires free flap reconstructions, whose harvesting site often requires a thin-skin graft. Wounds from the thin-skin donor site are comparable to an intermediate...
Fri Sep 13, 2019 14:32
Related ArticlesClavien-Dindo classification for grading complications after total pharyngolaryngectomy and free jejunum transfer. PLoS One. 2019;14(9):e0222570 Authors: Miyamoto S, Nakao J, Higashino T, Yoshimoto S, Hayashi R, Sakuraba M Abstract BACKGROUND: The frequency of postoperative complications is used as an indicator of surgical quality; however, comparison of outcomes is hampered by a lack of agreement on the definition of complications and...
Fri Sep 13, 2019 14:32
Related ArticlesAssociations among air pollutants, grass pollens, and daily number of grass pollen allergen-positive patients: a longitudinal study from 2012 to 2016. Int Forum Allergy Rhinol. 2019 Sep 12;: Authors: Ouyang Y, Yin Z, Li Y, Fan E, Zhang L Abstract BACKGROUND: Grass pollen is the most prevalent sensitizing aeroallergen to cause respiratory allergies in northern China. Air pollutants have a substantial effect on respiratory health and some...
Fri Sep 13, 2019 14:32
Related ArticlesGross tumor volume segmentation for head and neck cancer radiotherapy using deep dense multi-modality network. Phys Med Biol. 2019 Sep 12;: Authors: Guo Z, Guo N, Gong K, Zhong S, Li Q Abstract In radiation therapy, the accurate delineation of gross tumor volume (GTV) is crucial for treatment planning. However, it is challenging for head and neck cancer (HNC) due to the morphology complexity of various organs in the head, low targets...
Fri Sep 13, 2019 14:32
Related ArticlesA Surgical Procedure Grid for Safety and Operating Room Communication in Multisite Surgery. JAMA Facial Plast Surg. 2018 May 01;20(3):185-186 Authors: Insalaco LF, Spiegel JH PMID: 29327040 [PubMed - indexed for MEDLINE]
Sat Sep 14, 2019 13:08
Related ArticlesThe role of adjuvant treatment in early-stage oral cavity squamous cell carcinoma: An international collaborative study. Cancer. 2018 07 15;124(14):2948-2955 Authors: Fridman E, Na'ara S, Agarwal J, Amit M, Bachar G, Villaret AB, Brandao J, Cernea CR, Chaturvedi P, Clark J, Ebrahimi A, Fliss DM, Jonnalagadda S, Kohler HF, Kowalski LP, Kreppel M, Liao CT, Patel SG, Patel RS, Robbins KT, Shah JP, Shpitzer T, Yen TC, Zöller JE, Gil Z, International Consortium...
Sat Sep 14, 2019 13:08
Related ArticlesThe Physician's Prayer. Am J Med. 2019 01;132(1):121-123 Authors: Talwar AA PMID: 29969610 [PubMed - indexed for MEDLINE]
Sat Sep 14, 2019 13:08
Related ArticlesIrradiance controls photodynamic efficacy and tissue heating in experimental tumours: implication for interstitial PDT of locally advanced cancer. Br J Cancer. 2018 11;119(10):1191-1199 Authors: Shafirstein G, Bellnier DA, Oakley E, Hamilton S, Habitzruther M, Tworek L, Hutson A, Spernyak JA, Sexton S, Curtin L, Turowski SG, Arshad H, Henderson B Abstract BACKGROUND: Currently delivered light dose (J/cm2) is the principal parameter...
Sat Sep 14, 2019 13:08
Related ArticlesEditorial introduction. Curr Opin Otolaryngol Head Neck Surg. 2019 Apr;27(2):v Authors: PMID: 30844922 [PubMed - indexed for MEDLINE]
Sat Sep 14, 2019 13:08
Related ArticlesChemoresistance in Pancreatic Cancer. Int J Mol Sci. 2019 Sep 11;20(18): Authors: Zeng S, Pöttler M, Lan B, Grützmann R, Pilarsky C, Yang H Abstract Pancreatic ductal adenocarcinoma (PDAC), generally known as pancreatic cancer (PC), ranks the fourth leading cause of cancer-related deaths in the western world. While the incidence of pancreatic cancer is displaying a rising tendency every year, the mortality rate has not decreased significantly...
Sat Sep 14, 2019 13:08
Related ArticlesThe miR-205-5p/BRCA1/RAD17 Axis Promotes Genomic Instability in Head and Neck Squamous Cell Carcinomas. Cancers (Basel). 2019 Sep 11;11(9): Authors: Valenti F, Sacconi A, Ganci F, Grasso G, Strano S, Blandino G, Agostino SD Abstract Defective DNA damage response (DDR) is frequently associated with tumorigenesis. Abrogation of DDR leads to genomic instability, which is one of the most common characteristics of human cancers. TP53 mutations...
Sat Sep 14, 2019 13:08
Related ArticlesMulti-institutional evaluation of knowledge-based planning performance of volumetric modulated arc therapy (VMAT) for head and neck cancer. Phys Med. 2019 Aug;64:174-181 Authors: Kamima T, Ueda Y, Fukunaga JI, Shimizu Y, Tamura M, Ishikawa K, Monzen H Abstract PURPOSE: The aim of this study was to investigate whether additional manual objectives are necessary for the RapidPlan (RP) with a single optimization. We conducted multi-institutional...
Sat Sep 14, 2019 13:08
Related ArticlesImaging of adult nasal obstruction. Clin Radiol. 2019 Sep 09;: Authors: Whyte A, Boeddinghaus R Abstract The commonest causes of nasal obstruction are rhinitis and chronic rhinosinusitis, which affect up to 30% and 14% of the adult population, respectively. The global financial burden is huge, estimated at $5 billion for rhinitis and $8.6 billion for chronic rhinosinusitis per annum in the USA. On referral for imaging, computed tomography...
Sat Sep 14, 2019 13:08
Related ArticlesHematologic malignancies of the larynx: A single institution review. Am J Otolaryngol. 2019 Sep 04;:102285 Authors: Dewan K, Campbell R, Damrose EJ Abstract BACKGROUND: Primary hematologic malignancies of the larynx are rare diagnoses, accounting for less than 1% of all laryngeal tumors. They most commonly present as submucosal masses of the supraglottis, with symptoms including hoarseness, dysphagia, dyspnea and rarely cervical lymphadenopathy....
Sat Sep 14, 2019 13:08
Related ArticlesInhibitor of γ-secretase alleviates middle ear inflammation by regulating Th2 response in OVA-mediated allergic OME in vivo. Immunobiology. 2019 Aug 25;: Authors: Zhao C, Li J, Yang J, Yang L, Chen P, Dou J, Zhao S Abstract Otitis media with effusion (OME) often occurs in infants and young children, which is related to allergic reactions. Notch signaling pathway plays an important role in allergic responses. In this study, we aimed to...
Sat Sep 14, 2019 13:08
Related ArticlesAnatomical and functional rehabilitation after total bilateral maxillectomy using a custom-made bone-anchored titanium prosthesis. Int J Oral Maxillofac Surg. 2019 Sep 09;: Authors: Gueutier A, Kün-Darbois JD, Laccourreye L, Breheret R Abstract Surgical reconstruction after a total maxillectomy remains challenging. The standard treatment is the microvascular free flap. In cases of surgical contraindication, oral rehabilitation is usually...
Sat Sep 14, 2019 13:08
Related ArticlesShould multifocality be an indication for completion thyroidectomy in papillary thyroid carcinoma? Surgery. 2019 Sep 09;: Authors: Harries V, Wang LY, McGill M, Xu B, Tuttle RM, Wong RJ, Shaha AR, Shah JP, Ghossein R, Patel SG, Ganly I Abstract BACKGROUND: Multifocality in papillary thyroid carcinoma is common. The aim of this study is to determine whether patients with multifocal disease, treated with lobectomy alone, have an increased...
Sat Sep 14, 2019 13:08
Related ArticlesComparison of high-flow oxygen therapy with standard oxygen therapy for prevention of postoperative pulmonary complications after major head and neck surgery involving insertion of a tracheostomy: a feasibility study. Br J Oral Maxillofac Surg. 2019 Sep 09;: Authors: Twose P, Thomas C, Morgan M, Broad MA Abstract Major operations on the head and neck that involve microvascular reconstruction and a tracheostomy are prolonged procedures...
Sat Sep 14, 2019 13:08
Related ArticlesDrug sensitivity prediction models reveal a link between DNA repair defects and poor prognosis in HNSCC. Cancer Res. 2019 Sep 12;: Authors: Essers PBM, van der Heijden M, Verhagen CVM, Ploeg EM, de Roest RH, Leemans CR, Brakenhoff RH, van den Brekel MWM, Bartelink H, Verheij M, Vens C Abstract Head and neck squamous cell carcinoma (HNSCC) is characterized by the frequent manifestation of DNA crosslink repair defects. We established novel...
Sat Sep 14, 2019 13:08
Related ArticlesRisk factors for head and neck cancer in the World Trade Center Health Program General Responder Cohort: results from a nested case-control study. Occup Environ Med. 2019 Sep 12;: Authors: Bover Manderski MT, Black K, Udasin IG, Giuliano AR, Steinberg MB, Ohman Strickland P, Black TM, Dasaro CR, Crane M, Harrison D, Moline J, Luft BJ, Passannante MR, Lucchini RG, Todd AC, Graber JM Abstract OBJECTIVES: Head and neck cancers (HNCs) may...
Sat Sep 14, 2019 13:08
Related ArticlesSurgical Management of Primary Skull Base Osteosarcomas: Impact of Margin Status and Patterns of Relapse. Neurosurgery. 2019 Sep 12;: Authors: Raza SM, Habib A, Wang WL, Gildey PW, Conley AP, Nader ME, Hanna EY, Su SY, DeMonte F Abstract BACKGROUND: Skull base osteosarcomas are aggressive neoplasms characterized by bony invasion and extracompartmental/extra-osseous soft tissue extension that pose obstacles to achieving complete resection....
Sat Sep 14, 2019 13:08
Related ArticlesPleiotrophin increases neurite length and number of spiral ganglion neurons in vitro. Exp Brain Res. 2019 Sep 12;: Authors: Bertram S, Roll L, Reinhard J, Groß K, Dazert S, Faissner A, Volkenstein S Abstract Acoustic trauma, aging, genetic defects or ototoxic drugs are causes for sensorineural hearing loss involving sensory hair cell death and secondary degeneration of spiral ganglion neurons. Auditory implants are the only available...
Sat Sep 14, 2019 13:08
Related ArticlesComparison of postoperative cosmesis in transaxillary, postauricular facelift, and conventional transcervical thyroidectomy. Surg Endosc. 2019 Sep 12;: Authors: Lee DW, Ko SH, Song CM, Ji YB, Kim JK, Tae K Abstract BACKGROUND: The most important advantage of remote-access robotic and endoscopic thyroidectomies is believed to be the excellent postoperative cosmesis. The purpose of this study was to compare directly the postoperative cosmetic...
Sat Sep 14, 2019 13:08
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