Publication date: Available online 23 November 2019Source: International ImmunopharmacologyAuthor(s): A.P. Ferreira-Duarte, A.S. Pinheiro-Torres, W.M. Takeshita, V.O. Gushiken, I.A. Roncalho-Buck, G.F. Anhê, I.A. DeSouzaAbstractBackgroundThe lung infections by Staphylococcus aureus are strongly associated with its ability to produce enterotoxins. However, little is known about the mechanisms underlying trafficking of bone marrow (BM) neutrophils during airway inflammation induced by Staphylococcal...
Publication date: Available online 23 November 2019Source: International ImmunopharmacologyAuthor(s): Ruijuan Guan, Jian Wang, Defu Li, Ziying Li, Hanwei Liu, Mingjing Ding, Zhou Cai, Xue Liang, Qian Yang, Zhen Long, Lingzhu Chen, Wei Liu, Dejun Sun, Hongwei Yao, Wenju LuAbstractChronic obstructive pulmonary fibrosis (COPD) is a chronic and fatal lung disease with few treatment options. Sodium hydrosulfide (NaHS), a donor of hydrogen sulfide (H2S), was found to alleviate cigarette smoke (CS)-induced...
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Abstract The COL2A1 gene encodes the alpha‐1 chain of type II procollagen. Type II collagen, comprised of three identical alpha‐1 chains, is the major component of cartilage. COL2A1 gene variants are the etiologies of genetic diseases, termed type II collagenopathies, with a wide spectrum of clinical presentations. To date, at least 460 distinct COL2A1 mutations, identified in 663 independent probands, and 21 definite disorders have been reported. Nevertheless, a well‐defined genotype‐phenotype...
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Related ArticlesRadiation induced optic neuropathy: Does treatment modality influence the risk? Bull Cancer. 2019 Nov 19;: Authors: Mohamed Ali A, Mathis T, Bensadoun RJ, Thariat J Abstract Radiation induced optic neuropathy (RION) is a rare but disastrous complication of radiation therapy in treatment of periorbital tumors. The objective of this study is to investigate the incidence of RION in series of patients treated from peri orbital tumors by recent...
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875 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2019/11/24PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Related ArticlesPlasma DHA Is Related to Sleep Timing and Duration in a Cohort of Mexican Adolescents. J Nutr. 2019 Nov 23;: Authors: Jansen EC, Conroy DA, Burgess HJ, O'Brien LM, Cantoral A, Téllez-Rojo MM, Peterson KE, Baylin A Abstract BACKGROUND: Delayed sleep timing and short sleep duration represent a significant public health burden in adolescents. Whether intake of nutrients affects the pineal gland, where sleep/wake cycles are regulated, remains...
Related ArticlesThe World Cancer Research Fund/American Institute for Cancer Research Third Expert Report on Diet, Nutrition, Physical Activity, and Cancer: Impact and Future Directions. J Nutr. 2019 Nov 23;: Authors: Clinton SK, Giovannucci EL, Hursting SD Abstract The Third Expert Report on Diet, Nutrition, Physical Activity, and Cancer: A Global Perspective by the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR)...
Related ArticlesPork Products Have Digestible Indispensable Amino Acid Scores (DIAAS) That Are Greater Than 100 When Determined in Pigs, but Processing Does Not Always Increase DIAAS. J Nutr. 2019 Nov 23;: Authors: Bailey HM, Mathai JK, Berg EP, Stein HH Abstract BACKGROUND: Raw meat contains all indispensable amino acids (IAAs), but before human consumption, meat usually undergoes some degree of processing. Processing affects the 3-dimensional structure...
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21 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human physiology These pubmed results were generated on 2019/11/24PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Related ArticlesDysphonia screening in vocally trained and untrained children. Int J Pediatr Otorhinolaryngol. 2019 Nov 09;129:109776 Authors: Pribuisiene R, Pasvenskaite A, Pribuisis K, Balsevicius T, Liutkevicius V, Uloza V Abstract AIM: To evaluate dysphonia rate and impact of vocal training in vocally trained (VT) and vocally untrained (VUT) children using the Lithuanian version of Glottal Function Index (GFI-LT) questionnaire. METHODS:...
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Related ArticlesAn Intra-Operatively Diagnosed Case of Hemorrhagic Cholecystitis in a 43-year-old Patient: Case Report. Am J Case Rep. 2019 Nov 23;20:1732-1735 Authors: Khoury G, Nicolas G, Abou-Jaoude EA, Emmanuel N, Awdeh A, Bitar B, Saliba C, El Sayegh JSA, Osman D, Zaghrini E Abstract BACKGROUND Hemorrhagic cholecystitis is an uncommon occurrence in the setting of gallbladder pathology. It is a rare complication of acute cholecystitis that may have...
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Related ArticlesIs image interpretation in drug-induced sleep endoscopy that reliable? Sleep Breath. 2019 Nov 22;: Authors: Bartier S, Blumen M, Chabolle F Abstract PURPOSE: Previous studies have assessed drug-induced sleep endoscopy (DISE) as an interobserver reliable exam, with a learning curve effect. The objective was to check its assumed interobserver agreement and variability of between two groups of experienced and inexperienced French ENT physicians....
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Related ArticlesBeyond immunohistochemistry and immunocytochemistry: a current perspective on galectin-3 and thyroid cancer. Expert Rev Anticancer Ther. 2019 Nov 22;:1-11 Authors: Li J, Vasilyeva E, Wiseman SM Abstract Introduction: Thyroid nodules are very common in the general population, most are benign, and do not require any intervention. However, often a challenge exists in discriminating benign thyroid nodules from cancer, without performing a...
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Related ArticlesFirst do no harm: Preventing harm and optimizing care in psychogenic nonepileptic seizures. Epilepsy Behav. 2019 Nov 20;102:106642 Authors: Johnsen C, Ding HT Abstract Psychogenic nonepileptic seizures (PNES) are challenging clinical occurrences consisting of any combination of altered movement, sensation, or awareness that resemble epileptic seizures (ES) but do not coincide with electrographic ictal discharges and are presumed to be...
Related ArticlesThe management of epilepsy in clinical practice: Do the needs manifested by the patients correspond to the priorities of the caring physicians? Findings from the EPINEEDS Study. Epilepsy Behav. 2019 Nov 20;102:106641 Authors: Giussani G, Enia G, Bianchi E, Mecarelli O, Beghi E, EPINEEDS Study Group Abstract PURPOSE: The purpose of this study was to assess the priorities of patients with epilepsy and caring physicians and the correspondence...
Related ArticlesEfficacy and serum concentrations of perampanel for treatment of drug-resistant epilepsy in children, adolescents, and young adults: comparison of patients younger and older than 12 years. Seizure. 2019 Nov 05;73:75-78 Authors: Ikemoto S, Hamano SI, Hirata Y, Matsuura R, Koichihara R Abstract PURPOSE: Perampanel (PER) is a selective, non-competitive antagonist of the alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptor....
Related ArticlesMindfulness-based cognitive therapy for sexuality (MBCT-S) improves sexual functioning and intimacy among older women with epilepsy: A multicenter randomized controlled trial. Seizure. 2019 Nov 09;73:64-74 Authors: Lin CY, Potenza MN, Broström A, Blycker GR, Pakpour AH Abstract PURPOSE: Women with epilepsy (WWE) frequently experience sexual problems, including sexual dysfunction and sexual distress. Therefore, this study aimed to examine...
Related ArticlesDerivation of familial iPSC lines from three ASD patients carrying NRXN1α+/- and two controls (NUIGi022-A, NUIGi022-B; NUIGi023-A, NUIGi023-B; NUIGi025-A, NUIGi025-B; NUIGi024-A, NUIGi024-B; NUIGi026-A, NUIGi026-B). Stem Cell Res. 2019 Nov 13;41:101653 Authors: Ding Y, Marcó de la Cruz B, Xia Y, Liu M, Lu Y, McInerney V, Krawczyk J, Lynch SA, Howard L, O'Brien T, Gallagher L, Shen S Abstract NRXN1 copy number variation is a rare genetic...
Related ArticlesReduced cannabinoid 2 receptor activity increases susceptibility to induced seizures in mice. Epilepsia. 2019 Nov 22;: Authors: Shapiro L, Wong JC, Escayg A Abstract OBJECTIVE: The endocannabinoid system (ECS) is comprised of cannabinoid receptors 1 and 2 (CB1R and CB2R), endogenous ligands, and regulatory enzymes, and serves to regulate several important physiological functions throughout the brain and body. Recent evidence suggests...
Related ArticlesMethylmalonic Acidemia Complicated by Homocystinuria Diseases: a Report of Three Cases. Adv Ther. 2019 Nov 22;: Authors: Zhang YN, Pi YL, Yan X, Li YQ, Qi ZJ, Zhang HF Abstract This study aims to improve our understanding of methylmalonic acidemia (MMA) complicated by homocystinuria disease by analyzing the clinical characteristics, treatment response and prognosis of three patients. Hyperhomocysteinemia and developmental retardation...
Related ArticlesEffects of anterior thalamic nuclei stimulation on gene expression in a rat model of temporal lobe epilepsy. Acta Neurol Belg. 2019 Nov 22;: Authors: Liu DF, Chen YC, Zhu GY, Wang X, Jiang Y, Liu HG, Zhang JG Abstract Deep brain stimulation of the anterior nucleus of the thalamus (ANT-DBS) has been shown to be effective and safe in the long-term treatment of refractory epilepsy. However, the mechanisms by which ANT-DBS controls epilepsy...
Related ArticlesNew-onset super refractory status epilepticus: A case-series. Seizure. 2019 Nov 09;: Authors: Aurangzeb S, Prisco L, Adcock J, Speirs M, Raby S, Westbrook J, Sen A Abstract INTRODUCTION: Literature on New-Onset Refractory Status Epilepticus (NORSE) is scarce and management is guided mainly by retrospective reports, short case series or expert opinions. We aimed to add to the pool of the available data by retrospectively reviewing seven...
Related ArticlesCannabis Influences the Putative Cytokines-Related Pathway of Epilepsy among Egyptian Epileptic Patients. Brain Sci. 2019 Nov 20;9(12): Authors: M Taalab Y, Mohammed WF, Helmy MA, Othman AAA, Darwish M, Hassan I, Abbas M Abstract The study aims to investigate: (1) the prevalence of cannabis among epileptic patients seen at Mansoura University Hospital, (2) serum levels and gene expression of cytokines in epilepsy patients and the controls....
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Related ArticlesEarly laser intervention to reduce scar formation in wound healing by primary intention: A systematic review. J Plast Reconstr Aesthet Surg. 2019 Oct 11;: Authors: Behrouz-Pirnia A, Liu H, Peternel S, Dervishi G, Labeit A, Peinemann F Abstract BACKGROUND: Hypertrophic scars frequently follow primary closure of surgical wounds. Laser application at or shortly after suture may be associated with a reduction in scar formation, although the...
Related ArticlesFlap reconstruction for sacrectomy defects: A systematic review and meta-analysis. J Plast Reconstr Aesthet Surg. 2019 Oct 11;: Authors: Asaad M, Rajesh A, Wahood W, Vyas KS, Houdek MT, Rose PS, Moran SL Abstract BACKGROUND: Following the excision of sacral tumors, plastic surgeons are often faced with a large soft tissue defect that necessitates flap coverage to promote wound healing and obliterate the resulting dead space. We aimed...
Related ArticlesA case series of seven patients with recurrent median nerve neuropathy treated by the revision surgery of median nerve neurolysis and wrapping with radial artery perforator adipose flap. J Plast Reconstr Aesthet Surg. 2019 Oct 11;: Authors: Uemura T, Takamatsu K, Okada M, Yokoi T, Onode E, Miyashima Y, Konishi S, Nakamura H Abstract Adhesion neuropathy of the median nerve with persistent pain can be a challenging problem. Currently, coverage...
Related ArticlesReply to "Delays in adjuvant treatment and the impact on survival: Plastic surgeons be aware". J Plast Reconstr Aesthet Surg. 2019 Nov 12;: Authors: O'Neill AC, Hofer SOP PMID: 31757684 [PubMed - as supplied by publisher]
Related ArticlesDelays in adjuvant treatment and the impact on survival: Plastic surgeons be aware. J Plast Reconstr Aesthet Surg. 2019 Nov 12;: Authors: Davies J, Kiely J, Holmes WJ PMID: 31757683 [PubMed - as supplied by publisher]
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Accumulating evidence shows that the AMPK-mTOR pathway modulates autophagy via coordinated phosphorylation of ULK1. The aim of the present study was to investigate the relationship between AMPK, mTOR, and ULK1 during late exercise preconditioning (LEP), and to explore whether LEP-induced myocardial protection is related to the autophagy. The exercise preconditioning (EP) protocol was as follows: rats were instructed to for run four repeated in duration of 10 minutes (including 10 minutes rest between...
Acer truncatum, which is a new woody oil tree species, is an important ornamental and medicinal plant in China. To assess the genetic diversity and relationships of A. truncatum, we analyzed its complete chloroplast (cp) genome sequence. The A. truncatum cp genome comprises 156,492 bp, with the large single-copy, small single-copy, and inverted repeat (IR) regions consisting of 86,010, 18,050, and 26,216 bp, respectively. The A. truncatum cp genome contains 112 unique functional genes (i.e., 4 rRNA,...
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Related ArticlesOutcome parameters in speech audiometry: retrospective analysis of data and reporting quality in clinical studies. Eur Arch Otorhinolaryngol. 2019 Nov 23;: Authors: Morgenstern J, Lailach S, Zahnert T, Neudert M Abstract OBJECTIVES: The use of standardized outcome parameters is essential for the comparability of clinical studies. Pure-tone audiometry and speech audiometry are widely used, but there is no systematic evaluation of the outcome...
Sun Nov 24, 2019 14:23
Related ArticlesImpairment of nasal mucociliary clearance time in wood industry workers. Eur Arch Otorhinolaryngol. 2019 Nov 22;: Authors: Özler GS, Akoğlu E Abstract PURPOSE: The aim of this study is to investigate the effect of wood dust on nasal mucociliary clearance time in wood industry workers. Moreover, the correlation between duration of exposure to wood dust and nasal mucociliary clearance time will be evaluated. METHODS: A total of...
Sun Nov 24, 2019 14:23
Related ArticlesImage quality of flat-panel computed tomography using 2 different acquisition times versus multidetector computed tomography in whole-head temporal bone specimen. Eur Arch Otorhinolaryngol. 2019 Nov 22;: Authors: Reimann K, Hirt B, Schulze M Abstract PURPOSE: Imaging of temporal bone and skull base acquire high resolution due to the small anatomic structures with high clinical relevance. The purpose of this study was to compare image...
Sun Nov 24, 2019 14:23
Related Articles3D exoscopic surgery of lateral skull base. Eur Arch Otorhinolaryngol. 2019 Nov 22;: Authors: Rubini A, Di Gioia S, Marchioni D Abstract PURPOSE: The aim of the study is to assess whether the 3D exoscopic surgery technique could be used in lateral skull base surgery and if it could ultimately replace the microscope in the future. METHODS: This is a retrospective study in which were included 24 patients affected by lateral skull...
Sun Nov 24, 2019 14:23
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Abstract Allergen immunotherapy (AIT) is the only curative treatment for allergic diseases. It induces immune tolerance together with the reduction of the symptoms of asthma and allergic rhinitis patients. The common routes for the application of AIT for respiratory allergens are subcutaneous immunotherapy (SCIT) and sublingual immunotherapy (SLIT). SCIT improves the symptoms of asthma and rhinitis and increase the quality of life.
Abstract Delayed‐type, T‐cell mediated, drug hypersensitivity reactions are a serious unwanted manifestation of drug exposure that develops in a small percentage of the human population. Drugs and drug metabolites are known to interact directly and indirectly (through irreversible protein binding and processing to the derived adducts) with HLA proteins that present the drug‐peptide complex to T‐cells. Multiple forms of drug hypersensitivity are strongly linked to expression of a single HLA allele...
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Publication date: Available online 23 November 2019Source: Journal of Cranio-Maxillofacial SurgeryAuthor(s): Vikram Shetty, Nandakishore P, Adeeba Khanum, Anirudh Yadav, Hermann F. SailerAbstractObjectiveTemporomandibular joint ankylosis (TMJa) is a debilitating condition that causes difficulty in mastication, speech and mouth opening. Its treatment poses surgical and rehabilitative challenges along with a high incidence of reankylosis. This study was designed to assess the long-term outcomes with...
Publication date: Available online 23 November 2019Source: Journal of Cranio-Maxillofacial SurgeryAuthor(s): N. Leibig, A. Ha-Phuoc, G.B. Stark, R. Schmelzeisen, M.C. Metzger, S.U. Eisenhardt, P.J. VossSummaryThe Cook-Swartz-Doppler probe is an easy to handle and reliable tool for free flap monitoring. In the head and neck region different confounders can affect the read out. We therefore analyzed the use of the Doppler probe regarding these potential difficulties and to compare the diagnostic accuracy...
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