Purpose of review Right ventricular (RV) dysfunction following thoracotomy and pulmonary resection is a known phenomenon but questions remain about its mechanism, risk factors, and clinical significance. Acute RV dysfunction can present intraoperatively and postoperatively, persisting for 2 months after surgery. Recent findings Recently, the pulmonology literature has emphasized pulmonary arterial capacitance, rather than pulmonary vascular resistance, as a marker to predict disease progression...
Mon Nov 04, 2019 02:00
Conclusions: the early use of IVIG could contribute to an improvement and/or stabilization of visual symptoms in this patient group due to its rapid effect and lower profile of adverse effects when administered with chemotherapy. PMID: 31710513 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
07:58
Authors: Ahmad TR, Doan T, Gonzales JA, Acharya NR, Tsui E PMID: 31710511 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
07:58
IJERPH, Vol. 16, Pages 4452: A Study on The Driving Factors and Spatial Spillover of Carbon Emission Intensity in The Yangtze River Economic Belt under Double Control Action International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16224452 Authors: Xuhui Ding Zhongyao Cai Qianqian Xiao Suhui Gao It is greatly important to promote low-carbon green transformations in China, for implementing the emission reduction commitments and global climate governance....
02:00
Women who are experiencing intimate partner violence feel better supported, more confident, and less depressed when trained family doctors counsel them, according to new research in the journal Family Practice.
10:29
An innovative experiment underway on the International Space Station could help researchers make new progress in the fight against aggressive neurodegenerative diseases such as Alzheimer's and Parkinson's.
10:29
(University of Basel) Noise is not the same as noise -- and even a quiet environment does not have the same effect as white noise. With a background of continuous white noise, hearing pure sounds becomes even more precise, as researchers from the University of Basel have shown in a study in Cell Reports. Their findings could be applied to the further development of cochlear implants. (Source: EurekAlert! - Biology)MedWorm Message: Have you tried our new medical search engine? More powerful than before....
Tue Nov 12, 2019 06:00
Treatment TermsEar nose and throatEar DiseasesMeniere's DiseaseHearing lossBalance problemsSkull base tumorAcoustic neuromaCochlear implant surgeryCochlear Implant CandidateBone Conduction Hearing Aid Author Morgan deBlecourt Sub-Title Advanced Care for Complex Ear Diseases Overview If you ’re experiencing a serious ear-related concern that’s affecting your balance and/or hearing, you don’t have to live with it. An otologist or neurotologist is a highly specialized ear, nose, and throat...
Tue Oct 29, 2019 18:35
Environmental Science & TechnologyDOI: 10.1021/acs.est.9b03794
Tue Nov 12, 2019 07:00
Environmental Science & TechnologyDOI: 10.1021/acs.est.9b04022
Tue Nov 12, 2019 07:00
Environmental Science & TechnologyDOI: 10.1021/acs.est.9b04444
Tue Nov 12, 2019 07:00
Environmental Science & TechnologyDOI: 10.1021/acs.est.9b04983
Tue Nov 12, 2019 07:00
Environmental Science & TechnologyDOI: 10.1021/acs.est.9b04198
Tue Nov 12, 2019 07:00
Environmental Science & TechnologyDOI: 10.1021/acs.est.9b03236
Tue Nov 12, 2019 07:00
Environmental Science & TechnologyDOI: 10.1021/acs.est.9b04497
Tue Nov 12, 2019 07:00
Environmental Science & TechnologyDOI: 10.1021/acs.est.9b03875
Tue Nov 12, 2019 07:00
Environmental Science & TechnologyDOI: 10.1021/acs.est.9b05638
Tue Nov 12, 2019 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.9b04481
Tue Nov 12, 2019 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.9b04000
Tue Nov 12, 2019 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.9b04068
Tue Nov 12, 2019 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.9b03846
Tue Nov 12, 2019 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.9b03780
Tue Nov 12, 2019 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.9b03487
Tue Nov 12, 2019 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.9b04859
Tue Nov 12, 2019 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.9b04868
Tue Nov 12, 2019 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.9b04711
Tue Nov 12, 2019 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.9b04126
Tue Nov 12, 2019 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.9b04112
Tue Nov 12, 2019 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.9b03923
Tue Nov 12, 2019 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.9b03412
Tue Nov 12, 2019 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.9b04036
Tue Nov 12, 2019 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.9b04257
Tue Nov 12, 2019 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.9b01847
Tue Nov 12, 2019 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.9b03772
Tue Nov 12, 2019 07:00
Abstract Background Crohn’s disease is a chronic inflammatory condition that can affect the gut from mouth to anus. Gastroduodenal involvement is seen in less than 5% of all patients with Crohn’s disease. Among those cases, isolated gastric Crohn’s disease is even rarer. Although most patients with isolated gastric involvement have nonspecific complaints, very few of them do develop features of pyloric obstruction. There is a paucity...
02:00
Abstract Background Lithopedion is a word derived from the Greek words lithos, meaning stone, and paidion, meaning child, to describe a fetus that has become stony or petrified. Lithopedion is a rare complication of pregnancy which occurs when a fetus dies and becomes too large to be reabsorbed by the body. This entity in rare circumstances can be challenging for physicians to diagnose since it has a range of clinical manifestations....
Tue Nov 12, 2019 02:00
Infantile Onset of Spinocerebellar Ataxia Type 5 (SCA-5) in a 6 Month Old with Ataxic Cerebral Palsy
Abstract Spinocerebellar ataxia type 5 (SCA-5) is a predominantly slowly progressive adult onset ataxia. We describe a child with a presentation of ataxic cerebral palsy (CP) and developmental delay at 6 months of age. Genetic testing confirmed a c.812C>T p.(Thr271Ile) mutation within the SPTBN2 gene. Seven previous cases of infantile onset SCA-5 are reported in the literature, four of which had a CP presentation. Early onset of SCA-5 presents with ataxic CP and is a rare cause...
Tue Nov 12, 2019 02:00
By comparing short- and long-term outcomes following totally robotic radical distal gastrectomy (TRDG) and robotic-assisted radical distal gastrectomy (RADG), we aimed to assess in which modus operandi patient...
Mon Nov 11, 2019 02:00
Persistent descending mesocolon (PDM) is caused by the absence of fusion of the descending colon to the retroperitoneum. We herein report two colorectal cancer cases with PDM that were treated with laparoscopi...
Mon Nov 11, 2019 02:00
Biliary intraepithelial neoplasia (BilIN) is often distinguished by what it is not: the precancerous lesions are not mass-forming, are not the cause of bile duct obstruction, and are small enough (less than 5 ...
Mon Nov 11, 2019 02:00
The rate of breast-conserving surgery (BCS) is low in China. Many patients choose mastectomy even when informed that there is no difference in the overall survival rate compared with that of BCS plus radiother...
Mon Nov 11, 2019 02:00
The continuum of pro- and anti-inflammatory response elicited by traumatic brain injury (TBI) is suggested to play a key role in the outcome of TBI; however, the underlying mechanisms remain ill -defined.
Mon Nov 11, 2019 02:00
Parkinson’s disease (PD) is the second most common neurodegenerative disease in the world. Various studies have suggested that the immune response plays a key role in this pathology. While a predominantly pro-...
Mon Nov 11, 2019 02:00
Inflammatory mechanism has been implicated in delayed cerebral ischemia (DCI) and poor functional outcomes after subarachnoid hemorrhage (SAH). Identification of cytokine patterns associated with inflammation ...
Mon Nov 11, 2019 02:00
Bacterial infection is a potential risk factor for depression. However, little is known about the mechanistic link between bacterial endotoxin and depressive-like behaviors. The aim of the present study was to...
Mon Nov 11, 2019 02:00
This study compared the voice outcomes of selected patients with unilateral vocal fold palsy (UVFP) who underwent either nonselective laryngeal reinnervation (LR) or Type 1 thyroplasty (thyroplasty) in a Malaysian tertiary centre using multidimensional voice assessments. (Source: Journal of Voice)
Tue Nov 12, 2019 00:00
In this study we propose a new tool for the perceptual assessment of voice quality. For its design, we have adapted the Simplified Vocal Profile Analysis so that the new tool features two main characteristics: (1) the ordinal scalar degrees of the original protocol are turned into a visual analog scale; and (2) the original paper-based version of the protocol is now a computer-based implementation. In order to assess the reliability of the new tool, five phoneticians listened to 12 different speakers...
Mon Nov 11, 2019 00:00
We have conducted the first PET/CT study of cholinergic innervation of the gut in patients with esophagus cancer, who received radical surgical esophagectomy including vagotomy with comparison to healthy matched controls. We detected significantly decreased 11C‐donepezil PET signal in the small intestine and colon of vagotomized patients treated for esophagus cancer, suggesting that 11C‐donepezil PET can be used to assess damage to the parasympathetic nervous system in the GI‐tract. Abstract ...
Tue Nov 12, 2019 12:27
Firearm-related justifiable homicide and homicide in all 50 states were examined with respect to Stand Your Ground (SYG) laws. There was an increased rate of both justifiable homicide and homicide in SYG states pre- vs post-enactment of SYG laws. There was an increase in homicide and justifiable homicide in SYG compared with non-SYG states.
Tue Nov 12, 2019 02:00
“Neurosurgery is a human brain operating on another human brain—it is a human brain at its best operating on a human brain at its worst. To help a patient the doctor must be at his or her
Tue Nov 12, 2019 02:00
Abstract Purpose This study was designed to evaluate the association of non-genetic factors and polymorphisms CYP2C9*2 (rs1799853), CYP2C9*3 (rs1075910), and VKORC1-G1639A (rs9923231) with time in therapeutic range (TTR), and to build a regression model to predict the quality of oral anticoagulation control in a sample of Brazilian patients. Methods ...
Tue Nov 12, 2019 02:00
Abstract Considering that most deep learning based trackers capture accurate locations for targets at the expense of consuming much time in training phrase, in this paper we present a new powerful tracker using the Siamese network which can be implemented with low computation resource. Our proposed tracker can track targets accurately by a fine-tuned model which is convenient to train. During the tracking, we apply a new sampling method that is independent of training called action-selection...
Tue Nov 12, 2019 02:00
Contaminants in air, water, and food are linked directly or epidemiologically to neurologic diseases and neurodevelopmental disorders. Nanoparticle solids and endocrine disruptors are major factors. Medscape Medical News
00:48
Some diabetes and various neurologic and psychiatric disorders may share a genetic etiology with long-QT syndrome, suggests a population-based study. Medscape Medical News
Tue Nov 12, 2019 20:31
Use of marijuana is linked to a higher risk of stroke and hospitalization for cardiac arrhythmia in young people, two new studies suggest. Medscape Medical News
Tue Nov 12, 2019 19:00
Exposure to nitrogen dioxide during childhood raises the risk of schizophrenia, independent of genetic liability, results of a large, population-based study in Denmark show. Medscape Medical News
Tue Nov 12, 2019 17:07
Abstract The accurate 3D reconstruction of organs from radiological scans is an essential tool in computer-aided diagnosis (CADx) and plays a critical role in clinical, biomedical and forensic science research. The structure and shape of the organ, combined with morphological measurements such as volume and curvature, can provide significant guidance towards establishing progression or severity of a condition, and thus support improved diagnosis and therapy planning. Furthermore,...
Tue Nov 12, 2019 02:00
Abstract Purpose Probiotics may prevent healthcare-associated infections, such as ventilator-associated pneumonia, Clostridioides difficile-associated diarrhea, and other adverse outcomes. Despite their potential benefits, there are no summative data examining the cost-effectiveness of probiotics in hospitalized patients. This systematic review summarized studies evaluating the economic impact of using probiotics in hospitalized adult...
Tue Nov 12, 2019 02:00
Tue Nov 12, 2019 02:00
Abstract We investigated the role of autophagy, a controlled lysosomal degradation of cellular macromolecules and organelles, in glutamate excitotoxicity during nutrient deprivation in vitro. The incubation in low-glucose serum/amino acid-free cell culture medium synergized with glutamate in increasing AMP/ATP ratio and causing excitotoxic necrosis in SH-SY5Y human neuroblastoma cells. Glutamate suppressed starvation-triggered autophagy, as confirmed by diminished intracellular...
Tue Nov 12, 2019 02:00
Abstract The presence of macrophages within the plaque is a defining hallmark of atherosclerosis. Macrophages are exposed to various microenvironments such as oxidized lipids and cytokines which effect their phenotypic differentiation and activation. Classically, macrophages have been divided into two groups: M1 and M2 macrophages induced by T-helper 1 and T-helper 2 cytokines, respectively. However, for a decade, greater phenotypic heterogeneity and plasticity of these cells have...
Tue Nov 12, 2019 02:00
Abstract Hereditary fructose intolerance (HFI) is a rare inborn disease characterized by a deficiency in aldolase B, which catalyzes the cleavage of fructose 1,6-bisphosphate and fructose 1-phosphate (Fru 1P) to triose molecules. In patients with HFI, ingestion of fructose results in accumulation of Fru 1P and depletion of ATP, which are believed to cause symptoms, such as nausea, vomiting, hypoglycemia, and liver and kidney failure. These sequelae can be prevented by a fructose-restricted...
Tue Nov 12, 2019 02:00
Demand for pancreatic surgery is rising, occasionally necessitating consecutive PDs to be performed by a single surgeon in the same workday. The safety of this practice is unknown.
Tue Nov 12, 2019 02:00
Summary: Readmissions following a trauma have been well-studied, but little is known about the patients who return to the emergency department after they have been discharged. This paper describes the patient characteristics and risk factors associated with ED utilization following a trauma.
Tue Nov 12, 2019 02:00
From yeast to humans, the cell cycle is tightly controlled by regulatory networks that regulate cell proliferation and can be monitored by dynamic visual markers in living cells. We have observed S phase progression by monitoring nuclear accumulation of the FHA-containing DNA binding protein Tos4, which is expressed in the G1/S phase transition. We use Tos4 localization to distinguish three classes of DNA replication mutants: those that arrest with an apparent 1C DNA content and accumulate Tos4 at...
Tue Nov 12, 2019 22:18
Mycobacterium abscessus is a fast growing mycobacterium species mainly causing skin and respiratory infections in human. M. abscessus is resistant to numerous drugs, which is a major challenge for the treatment. In this study, we have sequenced the genomes of two clinical M. abscessus strains having rough and smooth morphology, using the single molecule real-time and Illumina HiSeq sequencing technology. In addition, we reported the first comparative methylome profiles of a rough and a smooth M....
Tue Nov 12, 2019 22:18
Abstract Objective to conduct a systematic review and meta‐analysis to evaluate the recent scientific literature addressing the association between periodontitis and asthma, chronic obstructive pulmonary disease (COPD), and pneumonia. Materials and Methods the search for studies was carried out using MedLine/PubMed, Embase, Lilacs, Web of Science, Scopus, and SciELO databases, including the gray literature (ProQuest). Reference lists of selected articles were also searched. Studies having...
Tue Nov 12, 2019 22:43
Abstract Objectives Using next‐generation sequencing (NGS) to determine whether aggressive periodontitis is associated with specific mitochondrial polymorphisms. Materials and Methods A total of 165 unrelated Han Chinese were enrolled in the study. We analyzed the mitochondrial DNA (mtDNA) in 97 patients with aggressive periodontitis and 68 healthy controls by NGS. The mitochondrial DNA was L‐PCR‐amplified and subsequently sequenced by an Illumina Genome Analyzer (NGS). Chi‐square tests...
Tue Nov 12, 2019 22:29
Abstract Objective To assess the association between polymorphic variants from SHMT1 and MTHFS genes, involved in the cytoplasmic futile folate cycle, and the risk of nonsyndromic cleft lip with or without cleft palate (NSCL/P) in the Chilean population. Subjects and Methods In a sample of 139 Chilean NSCL/P cases and 278 controls, we obtained the genotypes for 9 variants of SHMT1 and MTHFS and the association between them and the phenotype was evaluated using odds ratios (OR) in additive...
Mon Nov 11, 2019 20:24
Our data support that prior allergic disease, especially eczema, and corticosteroid treatment increase the risk of developing incident Hodgkin’s lymphoma before the age of 50. Immune system malfunction is central to Hodgkin’s lymphoma development.
Tue Nov 12, 2019 02:00
Tue Nov 12, 2019 02:00
Abstract Nursing has evolved, yet media representation has arguably failed to keep up. This work explores why representation has been slow in accurately depicting nurses' responsibilities, impacts on public perceptions and professional identity. A critical realist review was employed as this method enables in-depth exploration into why something exists. A multidisciplinary approach was adopted, drawing from feminist, psychological and sociological theories to provide insightful...
Tue Nov 12, 2019 02:00
Publication date: November 2019Source: Journal of Experimental Social Psychology, Volume 85Author(s): Iris K. Schneider, Marleen Gillebaart, André MattesAbstractSelf-control is a central construct in understanding human behavior and wellbeing, and has a significant impact on outcomes in several areas such as health, wellbeing, academic performance, and interpersonal relationships. However, underlying mechanisms of self-control, and particularly effortless self-control, remain underexposed. Recent...
00:13
Abstract Palliative care is an approach meant to improve the quality of life of patients facing life-threatening illness and to support their families. An international workshop on palliative care took place in Caesarea, Israel under the auspices of the National Institute for Health Policy Research on July 4-5th, 2018, with the goal of discussing challenges to the development and integration of palliative care services in Israel. At the workshop, both national and international...
Tue Nov 12, 2019 02:00
Journal Name: Journal of Pediatric Endocrinology and MetabolismIssue: Ahead of print
00:02
Journal Name: Journal of Pediatric Endocrinology and MetabolismIssue: Ahead of print
00:02
Journal Name: Journal of Pediatric Endocrinology and MetabolismIssue: Ahead of print
00:02
Abstract Purpose To establish the efficacy of oral antidepressants compared to placebo in improving obstructive sleep apnea (OSA) as measured on a polysomnography study. Secondary outcomes included self-reported sleepiness. Methods Authors identified prospective randomized placebo-controlled studies from MEDLINE through PubMed, Web of Science, the Cochrane...
Tue Nov 12, 2019 02:00
Abstract Objective To evaluate the performance of clinical criteria (CC) for diagnosis and initiation of empirical treatment with continuous positive airway pressure (CPAP) in patients with suspected obstructive sleep apnea (OSA) compared with the treatment decision based on sleep studies (polysomnography or respiratory polygraphy), guidelines, and experience of participating physicians. ...
Tue Nov 12, 2019 02:00
Academic medicine is experiencing an exponential increase in knowledge, evidenced by approximately 2.5 million new articles published each year. As a result, staying apprised of practice-changing findings as a busy clinician is nearly impossible. The traditional methods of staying up to date through reading textbooks and journal articles or attending an annual conference are no longer enough. These old approaches do not distribute knowledge equally around the world or inform practitioners adequately...
Tue Nov 12, 2019 02:00
Pediatric traumatic vascular injuries are rare. Given the paucity of data to guide anti-coagulation (AC) management of these injuries in children, who have a lower overall risk for thrombosis compared to their adult counterparts, we sought to examine and summarize our recent experience.
Tue Nov 12, 2019 02:00
Although the mucosectomy-commencing points on transanal endorectal pull-through (TAEPT) differ among reports, the optimal point is unclear. This study assessed the outcomes among different mucosectomy-commencing points.
Tue Nov 12, 2019 02:00
Eyevensys, a clinical-stage biotechnology company based in France, has developed a method to perform non-viral gene therapy in the eye, with the aim of treating ocular diseases. The system uses ocular electrotransfection to deliver therapeutic genes into the eye. Consisting of an ocular device and an electrical pulse generator, the system can deliver DNA plasmids into the ciliary muscle. The idea is that the transfected cells in the eye allow for sustained local production of therapeutic proteins,...
Tue Nov 12, 2019 23:38
Nevro, a firm based in Silicon Valley, won FDA approval for its Senza Omnia spinal cord neurostimulation system for chronic pain management. The device can deliver traditional spinal cord stimulation at frequencies below 1.5 kHz, along with Nevro’s proprietary HF10 stimulation that goes up to 10 kHz. Both low and high frequency therapies can even be provided at the same time. The Senza Omnia can operate at frequencies between 2 and 10,000 Hertz, a range unheard of in a spinal cord stimulator....
Tue Nov 12, 2019 19:35
Transcutaneous electrical muscle stimulation is used in a variety of clinical applications, including as a rehabilitation tool to help people with limited mobility. It is effective for maladies such as certain types of urinary incontinence, for example, but getting the muscles of the arm to move in unison and with appropriate strength via electrical stimulation through the skin is very difficult. Researchers at The Feinstein Institutes for Medical Research, a part of Northwell Health, a New...
Tue Nov 12, 2019 19:24
Researchers at the University of Wisconsin-Madison have developed an injectable flexible electrode that can aid in neuromodulation therapy, potentially replacing more rigid electrodes that do not mesh well with soft tissues. The injectable material consists of a silicone gel and small metal particles, and it forms a flexible bolus when injected around a target nerve. The nerve can then be electrically stimulated from the surface of the skin using a basic transcutaneous electrical nerve stimulation...
Tue Nov 12, 2019 17:17
Environmental Science & Technology LettersDOI: 10.1021/acs.estlett.9b00682
Tue Nov 12, 2019 07:00
Value of preoperative ultrasound in evaluating the peritoneal cancer index of pseudomyxoma peritonei
Abstract Purpose This study aimed to explore the value of preoperative ultrasonography (US) in evaluating the peritoneal cancer index (PCI) of pseudomyxoma peritonei (PMP). Methods An ultrasound examination was performed on 59 patients with PMP before surgery, and the ultrasound PCI was evaluated. The accuracy of ultrasound PCI score was evaluated...
Tue Nov 12, 2019 02:00
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.9b00940
Tue Nov 12, 2019 07:00
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.9b01210
Tue Nov 12, 2019 07:00
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.9b01344
Tue Nov 12, 2019 07:00
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.9b00988
Tue Nov 12, 2019 07:00
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.9b01000
Tue Nov 12, 2019 07:00
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου