Related ArticlesAdvanced Modeling to Predict Pneumonia in Combat Trauma Patients. World J Surg. 2019 Nov 20;: Authors: Bradley M, Dente C, Khatri V, Schobel S, Lisboa F, Shi A, Hensman H, Kirk A, Buchman TG, Elster E Abstract BACKGROUND: Tools to assist clinicians in predicting pneumonia could lead to a significant decline in morbidity. Therefore, we sought to develop a model in combat trauma patients for identifying those at highest risk of pneumonia....
Fri Nov 22, 2019 13:38
Related ArticlesThe FASILA Score: A Novel Bio-Clinical Score to Predict Massive Blood Transfusion in Patients with Abdominal Trauma. World J Surg. 2019 Nov 20;: Authors: El-Menyar A, Abdelrahman H, Al-Thani H, Mekkodathil A, Singh R, Rizoli S Abstract BACKGROUND: Early identification of patients who may need massive blood transfusion remains a major challenge in trauma care. This study proposed a novel and easy-to-calculate prediction score using clinical...
Fri Nov 22, 2019 13:38
Related ArticlesEndocrine Surgery Without the Bells and Whistles: Editorial of the International Association of Endocrine Surgeons Symposium. World J Surg. 2019 Nov 20;: Authors: Pasieka JL PMID: 31748886 [PubMed - as supplied by publisher]
Fri Nov 22, 2019 13:38
Related ArticlesLong-Term and Oncologic Outcomes of Robotic Versus Laparoscopic Liver Resection for Metastatic Colorectal Cancer: A Multicenter, Propensity Score Matching Analysis. World J Surg. 2019 Nov 20;: Authors: Beard RE, Khan S, Troisi RI, Montalti R, Vanlander A, Fong Y, Kingham TP, Boerner T, Berber E, Kahramangil B, Buell JF, Martinie JB, Vrochides D, Shen C, Molinari M, Geller DA, Tsung A Abstract BACKGROUND: To assess long-term oncologic...
Fri Nov 22, 2019 13:38
Related ArticlesLaparoscopic Major Hepatectomy: Do Not Underestimate the Impact of Specimen Extraction Site. World J Surg. 2019 Nov 20;: Authors: Guilbaud T, Feretti C, Holowko W, Garbarino GM, Marchese U, Sarran A, Beaussier M, Gayet B, Fuks D Abstract BACKGROUND: In laparoscopic major hepatectomy, analysis of outcomes according to specimen extraction site remains poorly described. The aim was to compare postoperative outcomes according to specimen...
Fri Nov 22, 2019 13:38
Related ArticlesThe Role of Lithium in Management of Endocrine Tumors-A Comprehensive Review. Front Oncol. 2019;9:1092 Authors: Thakur S, Tobey A, Klubo-Gwiezdzinska J Abstract Background: Epidemiological data reveal that treatment with lithium, a mood stabilizer, is associated with decreased incidence and mortality of certain cancer types, such as melanoma. Therefore, repositioning of lithium as an anticancer agent has emerged as a promising strategy...
Fri Nov 22, 2019 15:41
Related ArticlesChronic atrophic gastritis aggravate chronic periodontitis with Helicobacter pylori infection and CD4+Th cytokines infiltration. Histol Histopathol. 2019 Nov 21;:18187 Authors: Luo W, Li Y, Luo Z, Xu B Abstract OBJECTIVE: To investigate the potential effect of chronic atrophic gastritis on chronic periodontitis and further explore the possible mechanism. METHODS: Local periodontal lesions were collected from periodontitis tissues...
Fri Nov 22, 2019 13:33
Related ArticlesPredicting Hearing Loss After Radiotherapy and Cisplatin Chemotherapy in Patients With Head and Neck Cancer. JAMA Otolaryngol Head Neck Surg. 2019 Nov 21;: Authors: Schuette A, Lander DP, Kallogjeri D, Collopy C, Goddu S, Wildes TM, Daly M, Piccirillo JF Abstract Importance: Accurate, accessible predictions of posttreatment hearing loss for patients with head and neck cancer prior to the initiation of treatment are a necessary part of...
Fri Nov 22, 2019 14:33
Related ArticlesA review on immunohistochemical and histopathologic validation in PET-CT findings with consideration to microRNAs. Med Pharm Rep. 2019 Oct;92(4):337-345 Authors: Bădan MI, Bonci EA, Piciu D Abstract Purpose: This review provides an overview of some of the most recent clinical trials which investigated various types of cancer and other diseases, through the use of PET-CT imaging, highlighting the use of immunohistochemical stains or conventional...
Fri Nov 22, 2019 14:33
Related ArticlesEstablishing a Cohort of Transgender Men and Gender Nonconforming Individuals to Understand the Molecular Impact of Testosterone on Breast Physiology. Transgend Health. 2019;4(1):326-330 Authors: Baker GM, Pyle ME, Tobias AM, Bartlett RA, Phillips J, Fein-Zachary VJ, Wulf GM, Heng YJ Abstract Purpose: To characterize a cohort of transgender men and masculine-centered gender nonconforming individuals who underwent gender-affirming chest-contouring...
Fri Nov 22, 2019 14:33
Related ArticlesImpact of nonappendiceal cancer-specific death on overall survival: a competing risk analysis. Future Oncol. 2019 Nov 21;: Authors: Wu J, Man D, Wang K, Li L Abstract Aim: The occurrence of nonappendiceal cancer-specific death (non-ACSD) and its impact on overall survival are unclear. Methods: Patients were extracted from the Surveillance, Epidemiology, and End Results. Results: Nearly 33.2 and 24.0% patients suffered ACSD and non-ACSD....
Fri Nov 22, 2019 14:33
Related ArticlesImmune Checkpoint Inhibition in Non-metastatic Non-small Cell Lung Cancer: Chance for Cure? Drugs. 2019 Nov 20;: Authors: Heigener DF, Reck M Abstract Immune checkpoint inhibition of programmed-death receptor 1 (PD-1) or its ligand (PD-L1) has become a standard in the treatment of metastatic non-small cell lung cancer, either as monotherapy or in combination. Recently, it could be shown that immunotherapy works as consolidation after...
Fri Nov 22, 2019 13:33
Related ArticlesEnrichment of circulating myeloma cells by immunomagnetic beads combined with flow cytometry for monitoring minimal residual disease and relapse in patients with multiple myeloma. Ann Hematol. 2019 Nov 20;: Authors: Wang N, Tesfaluul N, Li J, Gao X, Liu S, Yue B Abstract Difficulty in regularly analyzing marrow myeloma cells (MMCs) and low frequency of circulating myeloma cells (CMCs) in blood presents challenges for monitoring minimal...
Fri Nov 22, 2019 13:33
Related ArticlesPatients' Perspectives on What Makes a Better Care Experience While Undergoing Treatment for Oropharyngeal Dysphagia Secondary to Head and Neck Cancer. Dysphagia. 2019 Nov 20;: Authors: Checklin M, Bain J, Bath L, Lethbridge K Abstract Patients' perceptions on what makes a better care experience for head and neck cancer (HNca) have not been widely sought. Patients' perceptions can play a crucial role in shaping quality care and client...
Fri Nov 22, 2019 13:33
Related ArticlesMutation Variants and Co-Mutations as Genomic Modifiers of Response to Afatinib in HER2-Mutant Lung Adenocarcinoma. Oncologist. 2019 Nov 20;: Authors: Fang W, Zhao S, Liang Y, Yang Y, Yang L, Dong X, Zhang L, Tang Y, Wang S, Yang Y, Ma X, Wang M, Wang W, Zhao S, Wang K, Gao S, Zhang L Abstract BACKGROUND: Human epidermal growth factor receptor 2 (HER2)-mutant lung cancer remains an orphan of specific targeted therapy. The variable responses...
Fri Nov 22, 2019 13:33
Related ArticlesDaily life participation in childhood chronic disease: a qualitative study. Arch Dis Child. 2019 Nov 20;: Authors: Nap-van der Vlist MM, Kars MC, Berkelbach van der Sprenkel EE, Nijhof LN, Grootenhuis MA, van Geelen SM, van der Ent CK, Swart JF, van Royen-Kerkhof A, van Grotel M, van de Putte EM, Nijhof SL Abstract OBJECTIVE: Opportunities to participate in daily life have improved considerably for children with chronic disease. Nevertheless,...
Fri Nov 22, 2019 13:33
Related ArticlesZnO nanocrystals shuttled by extracellular vesicles as effective Trojan nano-horses against cancer cells. Nanomedicine (Lond). 2019 Nov 21;: Authors: Dumontel B, Susa F, Limongi T, Canta M, Racca L, Chiodoni A, Garino N, Chiabotto G, Centomo ML, Pignochino Y, Cauda V Abstract Aim: The effective application of nanoparticles in cancer theranostics is jeopardized by their aggregation in biological media, rapid degradation and clearance....
Fri Nov 22, 2019 13:33
Related ArticlesNintedanib: new indication for systemic sclerosis-associated interstitial lung disease. Mod Rheumatol. 2019 Nov 21;:1-16 Authors: Kuwana M, Azuma A Abstract Nintedanib (Ofev™), an oral triple kinase inhibitor targeting pro-fibrotic pathways, has been used for treatment of idiopathic pulmonary fibrosis (IPF). Based on positive results from phase III, placebo-controlled, randomized comparative clinical trial conducted in patients with systemic...
Fri Nov 22, 2019 13:33
Related ArticlesTherapeutic potential of enhancer of zeste homolog 2 in autoimmune diseases. Expert Opin Ther Targets. 2019 Nov 20;: Authors: Yang YX, Shen HH, Cao F, Xie LY, Zhu GL, Sam NB, Wang DG, Pan HF Abstract Introduction: Autoimmune diseases are idiopathic and heterogeneous disorders with contentious pathophysiology. Great strides have been made in epigenetics and its involvement in autoimmune diseases. Zeste homolog 2 (EZH2) has sparked extensive...
Fri Nov 22, 2019 13:33
Related ArticlesInvasive lobular breast cancer: A review of pathogenesis, diagnosis, management, and future directions of early stage disease. Semin Oncol. 2019 04;46(2):121-132 Authors: Thomas M, Kelly ED, Abraham J, Kruse M Abstract Invasive lobular carcinoma (ILC) is the second most common type of invasive breast cancer after invasive ductal carcinoma (IDC). Invasive lobular carcinoma has unique clinical, pathologic, and radiographic features which...
Fri Nov 22, 2019 13:33
Related ArticlesProgrammed cell death ligand-1 expression in gastroenteropancreatic neuroendocrine tumors. J BUON. 2019 Mar-Apr;24(2):779-790 Authors: Oktay E, Yalcin GD, Ekmekci S, Kahraman DS, Yalcin A, Degirmenci M, Dirican A, Altin Z, Ozdemir O, Surmeli Z, Diniz G, Ayhan S, Bulut G, Erdogan A, Uslu R Abstract PURPOSE: Gastroenteropancreatic tumors (GEPNETs) is a heterogeneous disease with variable clinical course. While promising therapeutic options...
Fri Nov 22, 2019 13:33
Related ArticlesRisk factors for chemotherapy-induced nausea in pediatric patients receiving highly emetogenic chemotherapy. Pediatr Blood Cancer. 2019 04;66(4):e27584 Authors: Dupuis LL, Tamura RN, Kelly KM, Krischer JP, Langevin AM, Chen L, Kolb EA, Ullrich NJ, Sahler OJZ, Hendershot E, Stratton A, Sung L, McLean TW Abstract BACKGROUND: Little is known regarding risk factors for chemotherapy-induced nausea (CIN) in pediatric patients. PROCEDURE:...
Fri Nov 22, 2019 13:33
Related ArticlesHeading in a new direction? Recommendations for future research on patient decision aids. Patient Educ Couns. 2019 05;102(5):1029-1034 Authors: Herrmann A, Hall A, Zdenkowski N, Sanson-Fisher R Abstract Decision aids can improve a number of patient outcomes, but they are not commonly used in clinical practice. This commentary paper provides suggestions for potential next steps of decision aid research, with the aim to facilitate their...
Fri Nov 22, 2019 13:33
Related ArticlesPostoperative Pain and Wound Healing After Coblation-Assisted Barbed Anterior Pharyngoplasty (CABAPh): An Observational Study. Indian J Otolaryngol Head Neck Surg. 2019 Nov;71(Suppl 2):1157-1162 Authors: Rinaldi V, Costantino A, Moffa A, Cassano M, Mantovani M, Casale M, Pignataro L Abstract Despite the numerous progresses in the palatal surgery, one of the critical aspect of snoring and OSA surgery is the postoperative pain. Over the...
Fri Nov 22, 2019 15:29
Background: Spiration Valve System (SVS) is an alternative for patients with severe heterogeneous emphysema; however, data about efficacy from randomized controlled trials (RCT) are unclear. Objectives: To explore both efficacy and safety of SVS in patients with severe emphysema and hyperinflation. Methods: We included PubMed, EMBASE, Cochrane database. All searches were performed until August 2019. Only RCTs were included for analysis. Risk of bias was assessed using Cochrane risk of bias tool....
Fri Nov 22, 2019 13:05
Related ArticlesThe Gut Microbiota Links Dietary Polyphenols With Management of Psychiatric Mood Disorders. Front Neurosci. 2019;13:1196 Authors: Westfall S, Pasinetti GM Abstract The pathophysiology of depression is multifactorial yet generally aggravated by stress and its associated physiological consequences. To effectively treat these diverse risk factors, a broad acting strategy is required and is has been suggested that gut-brain-axis signaling...
Fri Nov 22, 2019 14:29
Related ArticlesArousal Contributions to Resting-State fMRI Connectivity and Dynamics. Front Neurosci. 2019;13:1190 Authors: Gu Y, Han F, Liu X Abstract Resting-state functional magnetic resonance imaging (rsfMRI) is being widely used for charting brain connectivity and dynamics in healthy and diseased brains. However, the resting state paradigm allows an unconstrained fluctuation of brain arousal, which may have profound effects on resting-state fMRI...
Fri Nov 22, 2019 14:29
Related ArticlesBrain-Blood Partition Coefficient and Cerebral Blood Flow in Canines Using Calibrated Short TR Recovery (CaSTRR) Correction Method. Front Neurosci. 2019;13:1189 Authors: Thalman SW, Powell DK, Ubele M, Norris CM, Head E, Lin AL Abstract The brain-blood partition coefficient (BBPC) is necessary for quantifying cerebral blood flow (CBF) when using tracer based techniques like arterial spin labeling (ASL). A recent improvement to traditional...
Fri Nov 22, 2019 14:29
Related ArticlesDivide and Conquer: Stratifying Training Data by Tumor Grade Improves Deep Learning-Based Brain Tumor Segmentation. Front Neurosci. 2019;13:1182 Authors: Rebsamen M, Knecht U, Reyes M, Wiest R, Meier R, McKinley R Abstract It is a general assumption in deep learning that more training data leads to better performance, and that models will learn to generalize well across heterogeneous input data as long as that variety is represented in...
Fri Nov 22, 2019 14:29
Related ArticlesThe Role of Brain Glycogen in Supporting Physiological Function. Front Neurosci. 2019;13:1176 Authors: Rich LR, Harris W, Brown AM Abstract Glycogen is present in the mammalian brain but occurs at concentrations so low it is unlikely to act as a conventional energy reserve. Glycogen has the intriguing feature of being located exclusively in astrocytes, but its presence benefits neurones, suggesting that glycogen is metabolized to a conduit...
Fri Nov 22, 2019 14:29
Related ArticlesComparison of Multi-Compartment Cable Models of Human Auditory Nerve Fibers. Front Neurosci. 2019;13:1173 Authors: Bachmaier R, Encke J, Obando-Leitón M, Hemmert W, Bai S Abstract Background: Multi-compartment cable models of auditory nerve fibers have been developed to assist in the improvement of cochlear implants. With the advancement of computational technology and the results obtained from in vivo and in vitro experiments, these...
Fri Nov 22, 2019 14:29
Related ArticlesThe Neural Correlates of Consciousness and Attention: Two Sister Processes of the Brain. Front Neurosci. 2019;13:1169 Authors: Nani A, Manuello J, Mancuso L, Liloia D, Costa T, Cauda F Abstract During the last three decades our understanding of the brain processes underlying consciousness and attention has significantly improved, mainly because of the advances in functional neuroimaging techniques. Still, caution is needed for the correct...
Fri Nov 22, 2019 14:29
Related ArticlesAftereffect and Reproducibility of Three Excitatory Repetitive TMS Protocols for a Response Inhibition Task. Front Neurosci. 2019;13:1155 Authors: Ji GJ, Wei JJ, Liu T, Li D, Zhu C, Yu F, Tian Y, Wang K, Zhang L, Hu P Abstract A number of repetitive transcranial magnetic stimulation (rTMS) protocols have been developed for modulating brain function non-invasively. To identify the most powerful one, these protocols have been compared in...
Fri Nov 22, 2019 14:29
Related ArticlesEffects of Noisy Galvanic Vestibular Stimulation During a Bimanual Tracking Robotic Task. Front Neurosci. 2019;13:1132 Authors: Valdés BA, Menon C Abstract Background: Noisy galvanic vestibular stimulation (nGVS) has been shown to improve motor performance in people with and without disabilities. Previous investigations on the use of nGVS to improve upper-limb motor performance have focused on unimanual fine motor movements, nevertheless,...
Fri Nov 22, 2019 14:29
Related ArticlesDifferent Heat Shock Proteins Bind α-Synuclein With Distinct Mechanisms and Synergistically Prevent Its Amyloid Aggregation. Front Neurosci. 2019;13:1124 Authors: Jia C, Ma X, Liu Z, Gu J, Zhang X, Li D, Zhang S Abstract α-Synuclein (α-Syn) forms pathological amyloid aggregates deposited in Lewy bodies and Lewy neurites in the brain of Parkinson's disease (PD) patients. Heat shock proteins (Hsps) are the major components of the cellular...
Fri Nov 22, 2019 14:29
Related ArticlesEnriched Environmental Conditions Modify the Gut Microbiome Composition and Fecal Markers of Inflammation in Parkinson's Disease. Front Neurosci. 2019;13:1032 Authors: Singh Y, El-Hadidi M, Admard J, Wassouf Z, Schulze-Hentrich JM, Kohlhofer U, Quintanilla-Martinez L, Huson D, Riess O, Casadei N Abstract Recent findings suggest an implication of the gut microbiome in Parkinson's disease (PD) patients. PD onset and progression has also...
Fri Nov 22, 2019 14:29
Related ArticlesLncRNA LINC00963 Promotes Tumorigenesis and Radioresistance in Breast Cancer by Sponging miR-324-3p and Inducing ACK1 Expression. Mol Ther Nucleic Acids. 2019 Oct 22;18:871-881 Authors: Zhang N, Zeng X, Sun C, Guo H, Wang T, Wei L, Zhang Y, Zhao J, Ma X Abstract Upregulation of long non-coding RNA LINC00963 has been observed in several cancer types. In this study, we analyzed the clinical and biological significance of LINC00963 in breast...
Fri Nov 22, 2019 14:27
Related ArticlesNon-extractable polyphenols from cranberries: potential anti-inflammation and anti-colon-cancer agents. Food Funct. 2019 Nov 21;: Authors: Han Y, Huang M, Li L, Cai X, Gao Z, Li F, Rakariyatham K, Song M, Fernández Tomé S, Xiao H Abstract Cranberries (Vaccinium macrocarpon) are full of polyphenols, which display various health benefits. Most studies have focused on extractable polyphenols (EPs) rather than non-extractable polyphenols...
Fri Nov 22, 2019 14:27
Related ArticlesSilencing of ARL14 Gene Induces Lung Adenocarcinoma Cells to a Dormant State. Front Cell Dev Biol. 2019;7:238 Authors: Guo F, Yuan D, Zhang J, Zhang H, Wang C, Zhu L, Zhang J, Pan Y, Shao C Abstract Recently, a growing number of ADP ribosylation factor (ARF) family members has been suggested to be critical in tumorigenesis. However, the effects of most ARF members on lung adenocarcinoma pathogenesis are still not well disclosed yet. In...
Fri Nov 22, 2019 14:27
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