Δευτέρα 4 Μαΐου 2020


Dysregulated signalling pathways in innate immune cells with cystic fibrosis mutations
Abstract Cystic fibrosis (CF) is one of the most common life-limiting recessive genetic disorders in Caucasians, caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR). CF is a multi-organ disease that involves the lungs, pancreas, sweat glands, digestive and reproductive systems and several other tissues. This debilitating condition is associated with recurrent lower respiratory tract bacterial and viral infections, as well as inflammatory complications...
Latest Results for Cellular and Molecular Life Sciences
5h
Activation of stress response axis as a key process in environment-induced sex plasticity in fish
Abstract The determination of sex is an important hallmark in the life cycle of organisms, in which the fate of gonads and then the individual sex are defined. In gonochoristic teleost fish, this process is characterized by a high plasticity, considering that in spite of genotypic sex many environmental factors can cause shifts from one to another molecular pathway, resulting in organisms with mismatching genotypic and phenotypic sexes. Interestingly, in most instances, both female-to-male...
Latest Results for Cellular and Molecular Life Sciences
13h

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