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The Journal of Antibiotics, Published online: 09 July 2020; doi:10.1038/s41429-020-0344-zPossible drugs for the treatment of bacterial infections in the future: anti-virulence drugs
Thu Jul 09, 2020 03:00
The Journal of Antibiotics, Published online: 09 July 2020; doi:10.1038/s41429-020-0343-0The genome insights of Streptomyces lannensis T1317-0309 reveals actinomycin D production
Thu Jul 09, 2020 03:00
Thu Jul 09, 2020 03:00
Fangs are a putative key innovation that revolutionized prey capture and feeding in snakes, and – along with their associated venom phenotypes – have made snakes perhaps the most medically-significant vertebra...
Thu Jul 09, 2020 03:00
Surgical Infections, Ahead of Print.
Wed Jul 08, 2020 10:00
Tissue Engineering Part A, Ahead of Print.
Thu Jul 09, 2020 10:00
Abstract Purpose The aim of the present study was to assess vitamin D levels in a large cohort of OSA patients and to investigate possible correlations with clinical and polysomnographic parameters. Methods In this cross-sectional study, 685 consecutive patients underwent type 1 polysomnography (PSG) for OSA diagnosis. They were grouped according to...
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Abstract Objective The aim of this study is to evaluate the impact of rapid palatal expansion (RPE) on the nasal airway subjectively by utilizing patient-reported outcome measures (PROM) and objectively by evaluating validated internal nasal valve (INV) measurements obtained from cone beam computed tomography (CBCT) in pediatrics. Materials and methods ...
Thu Jul 09, 2020 03:00
Abstract Background Insomnia disorder is characterized by nighttime and daytime symptoms. The aim of this study was to assess the validity and reliability of a Persian version of the Insomnia Diurnal Impact Scale (IDIS) as a screening tool to evaluate diurnal effects of sleep fragmentation in Iranians. Methods Of 300 individuals recruited, 150 had...
Thu Jul 09, 2020 03:00
Abstract Percutaneous collagen induction (PCI) is an alternative treatment for skin dysfunctions, it aims to stimulate collagen production by encouraging normal wound healing that occurs after any trauma by inducing microlesions; also it may be potentiated with the association with drugs such as hyaluronic acid (HA). Our objective was to evaluate the effects of PCI associated with hyaluronic acid (0.9%) on inflammatory process, oxidative...
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Abstract Acute pancreatitis (AP), a sudden inflammatory process of pancreas, is painful and may contribute to death. The aberrant expression of miR-27a-5p has been reported in many types of cancers and diseases including AP. Thus, it is urgent to manifest the functions and mechanism of miR-27a-5p in AP. The levels of miR-27a-5p, tumor necrosis factor (TNF) receptor–associated factor 3 (Traf3) in serum of AP patient, or cerulein-treated...
Thu Jul 09, 2020 03:00
Abstract Caves play an important ecological role for nonhuman primates in Africa and Asia. Savanna chimpanzees (Pan troglodytes verus) living in the Mandingue plateau of Senegal and Mali use caves for thermoregulation, where these refugia provide a cool microclimate during the hot, dry season. In this study, we examined cave use frequency for a chimpanzee community in southeastern Senegal. We used images from a camera trap placed at the mouth of a large laterite cave to investigate...
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Chlorophyll biosynthesis and chloroplast development are crucial to photosynthesis and plant growth, but their regulatory mechanism remains elusive in many crop species. We isolated a Brassica napus yellow-virescent leaf (yvl) mutant, which exhibited yellow-younger-leaf and virescent-older-leaf with decreased chlorophyll accumulation and delayed chloroplast development. We mapped yvl locus to a 70-kb interval between molecular markers yvl-O10 and InDel-O6 on chromosome A03 in BC2F2 population using...
Thu Jul 09, 2020 23:19
Evolve and resequence (E&R) experiments, in which artificial selection is imposed on organisms in a controlled environment, are becoming an increasingly accessible tool for studying the genetic basis of adaptation. Previous work has assessed how different experimental design parameters affect the power to detect the quantitative trait loci (QTLs) that underlie adaptive responses in such experiments, but so far there has been little exploration of how this power varies with the genetic architecture...
Thu Jul 09, 2020 23:19
Grown-up congenital heart (GUCH) patients represent a growing population with a high morbidity risk when undergoing reparative surgery. A main preoperative feature is right ventricular failure, which represent...
Thu Jul 09, 2020 03:00
Biologists have traced the stability of plant mitochondrial genomes to a particular gene - MSH1 - that plants have but animals don't. Their experiments could lend insight into why animal mitochondrial genomes tend to mutate.
Thu Jul 09, 2020 22:01
A report offers a detailed description of the first nearly complete skeleton of an extinct large dolphin, discovered in what is now South Carolina. The 15-foot-long dolphin (Ankylorhiza tiedemani comb. n.) lived during the Oligocene -- about 25 million years ago -- and was previously known only from a partial rostrum (snout) fossil.
Thu Jul 09, 2020 18:35
How does evolution impact ecological patterns? It helps smooth out the rough edges, say researchers. A new review of the history of ecological and evolutionary research establishes a framework to better understand evolution's impact on ecosystem patterns.
Thu Jul 09, 2020 17:52
Oncogenesis, Published online: 09 July 2020; doi:10.1038/s41389-020-00250-6Exploring and modelling colon cancer inter-tumour heterogeneity: opportunities and challenges
Thu Jul 09, 2020 03:00
Thu Jul 09, 2020 03:00
Abstract Objectives To investigate the correlation between gingival phenotype and craniofacial profile and to evaluate the morphology of periodontal supporting tissues in the maxillary and mandibular anterior zones. Materials and methods A total of 66 patients with 264 central incisors in good periodontal health were included in this cross-sectional study....
Thu Jul 09, 2020 03:00
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