IJMS, Vol. 21, Pages 4862: Cyclic AMP: A Polyhedral Signalling Molecule in Plants International Journal of Molecular Sciences doi: 10.3390/ijms21144862 Authors: Blanco Fortunato Viggiano de Pinto The cyclic nucleotide cAMP (3′,5′-cyclic adenosine monophosphate) is nowadays recognised as an important signalling molecule in plants, involved in many molecular processes, including sensing and response to biotic and abiotic environmental stresses. The validation...
Thu Jul 09, 2020 03:00
IJMS, Vol. 21, Pages 4864: New Insight into Natural Extracellular Matrix: Genipin Cross-Linked Adipose-Derived Stem Cell Extracellular Matrix Gel for Tissue Engineering International Journal of Molecular Sciences doi: 10.3390/ijms21144864 Authors: Nyambat Manga Chen Gankhuyag Pratomo WP Kumar Satapathy Chuang The cell-derived extracellular matrix (ECM) is associated with a lower risk of pathogen transfer, and it possesses an ideal niche with growth factors and...
Thu Jul 09, 2020 03:00
IJMS, Vol. 21, Pages 4859: Drosophila Glia: Models for Human Neurodevelopmental and Neurodegenerative Disorders International Journal of Molecular Sciences doi: 10.3390/ijms21144859 Authors: Taejoon Kim Bokyeong Song Im-Soon Lee Glial cells are key players in the proper formation and maintenance of the nervous system, thus contributing to neuronal health and disease in humans. However, little is known about the molecular pathways that govern glia–neuron communications...
Thu Jul 09, 2020 03:00
IJMS, Vol. 21, Pages 4858: Crop Enhancement of Cucumber Plants under Heat Stress by Shungite Carbon International Journal of Molecular Sciences doi: 10.3390/ijms21144858 Authors: Tae Yoon Kim Hara Ku Seung-Yop Lee Heat stress negatively impacts plant growth and yield. The effects of carbon materials on plants in response to abiotic stress and antioxidant activity are poorly understood. In this study, we propose a new method for improving heat tolerance in cucumber (Cucumis sativus...
Thu Jul 09, 2020 03:00
IJMS, Vol. 21, Pages 4857: Identification and Functional Characterization of PtoMYB055 Involved in the Regulation of the Lignin Biosynthesis Pathway in Populus tomentosa International Journal of Molecular Sciences doi: 10.3390/ijms21144857 Authors: Yiming Sun Sha Ren Shenglong Ye Qiaoyan Tian Keming Luo Wood, which is mainly composed of lignified secondary cell wall, is the most abundant biomass in woody plants. Previous studies have revealed that R2R3-type MYB transcription...
Thu Jul 09, 2020 03:00
IJMS, Vol. 21, Pages 4856: EIF4G1 and RAN as Possible Drivers for Malignant Pleural Mesothelioma International Journal of Molecular Sciences doi: 10.3390/ijms21144856 Authors: Irene Dell’Anno Marcella Barbarino Elisa Barone Antonio Giordano Luca Luzzi Maria Bottaro Loredana Migliore Silvia Agostini Alessandra Melani Ombretta Melaiu Calogerina Catalano Monica Cipollini Roberto Silvestri Alda Corrado Federica Gemignani Stefano Landi For malignant...
Thu Jul 09, 2020 03:00
IJMS, Vol. 21, Pages 4855: Toxicity of TiO2 Nanoparticles: Validation of Alternative Models International Journal of Molecular Sciences doi: 10.3390/ijms21144855 Authors: Mélanie M. Leroux Zahra Doumandji Laetitia Chézeau Laurent Gaté Sara Nahle Romain Hocquel Vadim Zhernovkov Sylvie Migot Jafar Ghanbaja Céline Bonnet Raphaël Schneider Bertrand H. Rihn Luc Ferrari Olivier Joubert There are many studies concerning titanium dioxide (TiO2) nanoparticles...
Thu Jul 09, 2020 03:00
IJMS, Vol. 21, Pages 4853: Metabolomic Insight into Polycystic Ovary Syndrome—An Overview International Journal of Molecular Sciences doi: 10.3390/ijms21144853 Authors: Anna Rajska Magdalena Buszewska-Forajta Dominik Rachoń Michał Jan Markuszewski Searching for the mechanisms of the polycystic ovary syndrome (PCOS) pathophysiology has become a crucial aspect of research performed in the last decades. However, the pathogenesis of this complex and heterogeneous endocrinopathy...
Thu Jul 09, 2020 03:00
IJMS, Vol. 21, Pages 4854: Plastid Transformation: How Does it Work? Can it Be Applied to Crops? What Can it Offer? International Journal of Molecular Sciences doi: 10.3390/ijms21144854 Authors: Yihe Yu Po-Cheng Yu Wan-Jung Chang Keke Yu Choun-Sea Lin In recent years, plant genetic engineering has advanced agriculture in terms of crop improvement, stress and disease resistance, and pharmaceutical biosynthesis. Cells from land plants and algae contain three organelles that...
Thu Jul 09, 2020 03:00
IJMS, Vol. 21, Pages 4850: Bergenin Reduces Experimental Painful Diabetic Neuropathy by Restoring Redox and Immune Homeostasis in the Nervous System International Journal of Molecular Sciences doi: 10.3390/ijms21144850 Authors: Cristiane F. Villarreal Dourivaldo S. Santos Pedro S. S. Lauria Kelly B. Gama Renan F. Espírito-Santo Paulo J. L. Juiz Clayton Q. Alves Jorge M. David Milena B. P. Soares Diabetic neuropathy is a frequent complication of diabetes. Symptoms...
Thu Jul 09, 2020 03:00
IJMS, Vol. 21, Pages 4852: WNT Signaling in Melanoma International Journal of Molecular Sciences doi: 10.3390/ijms21144852 Authors: Anna Gajos-Michniewicz Malgorzata Czyz WNT-signaling controls important cellular processes throughout embryonic development and adult life, so any deregulation of this signaling can result in a wide range of pathologies, including cancer. WNT-signaling is classified into two categories: β-catenin-dependent signaling (canonical pathway) and β-catenin-independent...
Thu Jul 09, 2020 03:00
IJMS, Vol. 21, Pages 4851: Green Synthesized Montmorillonite/Carrageenan/Fe3O4 Nanocomposites for pH-Responsive Release of Protocatechuic Acid and Its Anticancer Activity International Journal of Molecular Sciences doi: 10.3390/ijms21144851 Authors: Yen Pin Yew Kamyar Shameli Shaza Eva Mohamad Kar Xin Lee Sin-Yeang Teow Discovery of a novel anticancer drug delivery agent is important to replace conventional cancer therapies which are often accompanied by undesired side effects....
Thu Jul 09, 2020 03:00
IJMS, Vol. 21, Pages 4849: Dual Leucine Zipper Kinase Is Constitutively Active in the Adult Mouse Brain and Has Both Stress-Induced and Homeostatic Functions International Journal of Molecular Sciences doi: 10.3390/ijms21144849 Authors: Sunil Goodwani Celia Fernandez Paul J. Acton Virginie Buggia-Prevot Morgan L. McReynolds Jiacheng Ma Cheng Hui Hu Mary E. Hamby Yongying Jiang Kang Le Michael J. Soth Philip Jones William J. Ray Dual leucine zipper...
Thu Jul 09, 2020 03:00
IJMS, Vol. 21, Pages 4847: Following the Fate of Dye-Containing Liposomes In Vitro International Journal of Molecular Sciences doi: 10.3390/ijms21144847 Authors: Jennifer Cauzzo Mona Nystad Ann Mari Holsæter Purusotam Basnet Nataša Škalko-Basnet The rather limited success of translation from basic research to clinical application has been highlighted as a major issue in the nanomedicine field. To identify the factors influencing the applicability of nanosystems as drug carriers...
Thu Jul 09, 2020 03:00
IJMS, Vol. 21, Pages 4848: Concomitant Chemoradiation Therapy with Gold Nanoparticles and Platinum Drugs Co-Encapsulated in Liposomes International Journal of Molecular Sciences doi: 10.3390/ijms21144848 Authors: Gabriel Charest Thititip Tippayamontri Minghan Shi Mohamed Wehbe Malathi Anantha Marcel Bally Léon Sanche A liposomal formulation of gold nanoparticles (GNPs) and carboplatin, named LipoGold, was produced with the staggered herringbone microfluidic method....
Thu Jul 09, 2020 03:00
IJMS, Vol. 21, Pages 4846: Lipid Peroxidation and Chlorophyll Fluorescence of Photosystem II Performance during Drought and Heat Stress is Associated with the Antioxidant Capacities of C3 Sunflower and C4 Maize Varieties International Journal of Molecular Sciences doi: 10.3390/ijms21144846 Authors: Dilek Killi Antonio Raschi Filippo Bussotti Agricultural production is predicted to be adversely affected by an increase in drought and heatwaves. Drought and heat damage cellular membranes,...
Thu Jul 09, 2020 03:00
IJNS, Vol. 6, Pages 57: Newborn Screening for Cystic Fibrosis: Over the Hump, still Need to Fine-Tune It International Journal of Neonatal Screening doi: 10.3390/ijns6030057 Authors: Carlo Castellani Today, newborn screening (NBS) is considered an essential component in the standards of care for cystic fibrosis (CF) [...]
Thu Jul 09, 2020 03:00
JCM, Vol. 9, Pages 2176: Feasibility and Preliminary Effectiveness of a Tele-Prehabilitation Program in Esophagogastric Cancer Patients Journal of Clinical Medicine doi: 10.3390/jcm9072176 Authors: Elise Piraux Gilles Caty Gregory Reychler Patrice Forget Yannick Deswysen Tele-rehabilitation provides better access to healthcare services and optimizes exercise adherence. However, its feasibility and effectiveness are unknown in the preoperative period in esophagogastric cancer...
Thu Jul 09, 2020 03:00
JCM, Vol. 9, Pages 2174: Congruence between Meshes and Library Files of Implant Scanbodies: An In Vitro Study Comparing Five Intraoral Scanners Journal of Clinical Medicine doi: 10.3390/jcm9072174 Authors: Francesco Mangano Henriette Lerner Bidzina Margiani Ivan Solop Nadezhda Latuta Oleg Admakin Purpose. To compare the reliability of five different intraoral scanners (IOSs) in the capture of implant scanbodies (SBs) and to verify the dimensional congruence between the...
Thu Jul 09, 2020 03:00
JCM, Vol. 9, Pages 2172: Positive Fecal Immunochemical Test Results Are Associated with Increased Risks of Esophageal, Stomach, and Small Intestine Cancers Journal of Clinical Medicine doi: 10.3390/jcm9072172 Authors: Yoon Suk Jung Jinhee Lee Chang Mo Moon Background: The current guideline does not recommend upper gastrointestinal evaluation for patients with a positive fecal immunochemical test (FIT) and negative colonoscopy results. However, this indication was based on low-quality...
Thu Jul 09, 2020 03:00
JCM, Vol. 9, Pages 2175: Effects of Rapid Recovery on Alcohol Hangover Severity: A Double-Blind, Placebo-Controlled, Randomized, Balanced Crossover Trial Journal of Clinical Medicine doi: 10.3390/jcm9072175 Authors: Andrew Scholey Elizabeth Ayre Ann-Kathrin Stock Joris C Verster Sarah Benson The aim of this study was to evaluate the efficacy of putative hangover treatment, Rapid Recovery, in mitigating alcohol hangover (AH) symptom severity. Using a double-blind, randomized,...
Thu Jul 09, 2020 03:00
JCM, Vol. 9, Pages 2171: Strong Correlation of Renal Function with Choroidal Thickness in Patients with Type 2 Diabetes: Retrospective Cross-Sectional Study Journal of Clinical Medicine doi: 10.3390/jcm9072171 Authors: Min Gyu Choi Jee Taek Kim The purpose of this study was to analyze the correlation between renal function and subfoveal choroidal thickness (SFChT) in treatment-naïve proliferative diabetic retinopathy (PDR) patients. This study included 85 eyes of 52 treatment-naïve...
Thu Jul 09, 2020 03:00
JCM, Vol. 9, Pages 2170: Use of Guselkumab for the Treatment of Moderate-to-Severe Plaque Psoriasis: A 1 Year Real-Life Study Journal of Clinical Medicine doi: 10.3390/jcm9072170 Authors: Marco Galluzzo Lorenzo Tofani Paolo Lombardo Alessandra Petruzzellis Dionisio Silvaggio Colin Gerard Egan Luca Bianchi Marina Talamonti Little information is available from real-life studies evaluating the efficacy of guselkumab in moderate-to-severe psoriasis. In this real-life...
Thu Jul 09, 2020 03:00
JCM, Vol. 9, Pages 2173: The Effect of Lactobacillus acidophilus YT1 (MENOLACTO) on Improving Menopausal Symptoms: A Randomized, Double-Blinded, Placebo-Controlled Clinical Trial Journal of Clinical Medicine doi: 10.3390/jcm9072173 Authors: Eun Yeong Lim So-Young Lee Hee Soon Shin Jaekwang Lee Young-Do Nam Dong Ock Lee Ji Young Lee Sung Hum Yeon Rak Ho Son Chae Lee Park Yun Haeng Heo Yun Tai Kim This study evaluated the efficacy of Lactobacillus acidophilus...
Thu Jul 09, 2020 03:00
JCM, Vol. 9, Pages 2168: New Insights on Genetic Diagnostics in Cardiomyopathy and Arrhythmia Patients Gained by Stepwise Exome Data Analysis Journal of Clinical Medicine doi: 10.3390/jcm9072168 Authors: Konstantinos Kolokotronis Natalie Pluta Eva Klopocki Erdmute Kunstmann Daniel Messroghli Christoph Maack Shai Tejman-Yarden Michael Arad Simone Rost Brenda Gerull Inherited cardiomyopathies are characterized by clinical and genetic heterogeneity that challenge...
Thu Jul 09, 2020 03:00
JCM, Vol. 9, Pages 2169: Prognostic Implications of 18-FDG Positron Emission Tomography/Computed Tomography in Resectable Pancreatic Cancer Journal of Clinical Medicine doi: 10.3390/jcm9072169 Authors: Cosimo Sperti Alberto Friziero Simone Serafini Sergio Bissoli Alberto Ponzoni Andrea Grego Emanuele Grego Lucia Moletta There are currently no known preoperative factors for determining the prognosis in pancreatic cancer. The aim of this study was to examine the role...
Thu Jul 09, 2020 03:00
JCM, Vol. 9, Pages 2166: Bispecific Antibodies: A New Era of Treatment for Multiple Myeloma Journal of Clinical Medicine doi: 10.3390/jcm9072166 Authors: Xiang Zhou Hermann Einsele Sophia Danhof Despite the introduction of novel agents such as proteasome inhibitors, immunomodulatory drugs, and autologous stem cell transplant, multiple myeloma (MM) largely remains an incurable disease. In recent years, monoclonal antibody-based treatment strategies have been developed to target...
Thu Jul 09, 2020 03:00
JCM, Vol. 9, Pages 2167: Development and Validation of a Deep Learning System for Diagnosing Glaucoma Using Optical Coherence Tomography Journal of Clinical Medicine doi: 10.3390/jcm9072167 Authors: Ko Eun Kim Joon Mo Kim Ji Eun Song Changwon Kee Jong Chul Han Seung Hyup Hyun This study aimed to develop and validate a deep learning system for diagnosing glaucoma using optical coherence tomography (OCT). A training set of 1822 eyes (332 control, 1490 glaucoma) with 7288...
Thu Jul 09, 2020 03:00
JDB, Vol. 8, Pages 12: A Synthetic Peptide, CK2.3, Inhibits RANKL-Induced Osteoclastogenesis through BMPRIa and ERK Signaling Pathway Journal of Developmental Biology doi: 10.3390/jdb8030012 Authors: John Nguyen Semaj Kelly Ryan Wood Brian Heubel Anja Nohe The skeletal system plays an important role in the development and maturation process. Through the bone remodeling process, 10% of the skeletal system is renewed every year. Osteoblasts and osteoclasts are two major bone...
Thu Jul 09, 2020 03:00
Life, Vol. 10, Pages 108: Molecular Correlation between Larval, Deutonymph and Adult Stages of the Water Mite Arrenurus (Micruracarus) Novus Life doi: 10.3390/life10070108 Authors: Alarcón-Elbal García-Jiménez Peláez Horreo Valdecasas The systematics of many groups of organisms has been based on the adult stage. Morphological transformations that occur during development from the embryonic to the adult stage make it difficult (or impossible) to identify a juvenile (larval)...
Thu Jul 09, 2020 03:00
Medicina, Vol. 56, Pages 342: Postoperative Delirium in Patients with Chronic Obstructive Pulmonary Disease after Coronary Artery Bypass Grafting Medicina doi: 10.3390/medicina56070342 Authors: Aleksandra Szylińska Iwona Rotter Mariusz Listewnik Kacper Lechowicz Mirosław Brykczyński Sylwia Dzidek Maciej Żukowski Katarzyna Kotfis Background and Objectives: The incidence of postoperative delirium (POD) in patients with chronic obstructive pulmonary disease (COPD) is...
Thu Jul 09, 2020 03:00
Medicina, Vol. 56, Pages 341: Treatment Strategies for Pilonidal Sinus Disease in Switzerland and Austria Medicina doi: 10.3390/medicina56070341 Authors: Tenzin Lamdark Raphael Nicolas Vuille-dit-Bille Isabella Naomi Bielicki Laura C. Guglielmetti Rashikh A Choudhury Nora Peters Dietrich Doll Markus M Luedi Michel Adamina Background and objective: No current nationwide consensus exists on pilonidal disease (PD) treatment in Switzerland and Austria. The objective...
Thu Jul 09, 2020 03:00
Medicina, Vol. 56, Pages 340: Diagnostic Value of Circulating miR-202 in Early-Stage Breast Cancer in South Korea Medicina doi: 10.3390/medicina56070340 Authors: Jungho Kim Sunyoung Park Dasom Hwang Seung Il Kim Hyeyoung Lee Background and objectives: Breast cancer is the most common cancer among women worldwide. Early stage diagnosis is important for predicting increases in treatment success rates and decreases in patient mortality. Recently, circulating biomarkers such...
Thu Jul 09, 2020 03:00
Membranes, Vol. 10, Pages 147: Evaluation of an Integrated Ultrafiltration/Solid Phase Extraction Process for Purification of Oligomeric Grape Seed Procyanidins Membranes doi: 10.3390/membranes10070147 Authors: Alba Gutierrez-Docio Paula Almodóvar Silvia Moreno-Fernandez Jose Manuel Silvan Adolfo J. Martinez-Rodriguez Gonzalo Luis Alonso Marin Prodanov The effectiveness of a preparative integrated ultrafiltration/solid-phase extraction (UF/SPE) process for purification...
Thu Jul 09, 2020 03:00
Membranes, Vol. 10, Pages 146: Electrodialysis Applications in Wastewater Treatment for Environmental Protection and Resources Recovery: A Systematic Review on Progress and Perspectives Membranes doi: 10.3390/membranes10070146 Authors: Luigi Gurreri Alessandro Tamburini Andrea Cipollina Giorgio Micale This paper presents a comprehensive review of studies on electrodialysis (ED) applications in wastewater treatment, outlining the current status and the future prospect. ED is...
Thu Jul 09, 2020 03:00
Metabolites, Vol. 10, Pages 283: Transcriptional Regulation in Non-Alcoholic Fatty Liver Disease Metabolites doi: 10.3390/metabo10070283 Authors: Sandra Steensels Jixuan Qiao Baran A. Ersoy Obesity is the primary risk factor for the pathogenesis of non-alcoholic fatty liver disease (NAFLD), the worldwide prevalence of which continues to increase dramatically. The liver plays a pivotal role in the maintenance of whole-body lipid and glucose homeostasis. This is mainly mediated by...
Thu Jul 09, 2020 03:00
Metabolites, Vol. 10, Pages 282: Development and Validation of a Highly Sensitive LC-MS/MS Method for the Analysis of Bile Acids in Serum, Plasma, and Liver Tissue Samples Metabolites doi: 10.3390/metabo10070282 Authors: Cristina Gómez Simon Stücheli Denise V. Kratschmar Jamal Bouitbir Alex Odermatt Bile acids control lipid homeostasis by regulating uptake from food and excretion. Additionally, bile acids are bioactive molecules acting through receptors and modulating various...
Thu Jul 09, 2020 03:00
Metabolites, Vol. 10, Pages 281: Changes in the Fecal Metabolome Are Associated with Feeding Fiber Not Health Status in Cats with Chronic Kidney Disease Metabolites doi: 10.3390/metabo10070281 Authors: Jean A. Hall Dennis E. Jewell Eden Ephraim The objective was to determine the effects of feeding different fiber sources to cats with chronic kidney disease (CKD) compared with healthy cats (both n = 10) on fecal metabolites. A cross-over within split-plot study design was performed...
Thu Jul 09, 2020 03:00
MPs, Vol. 3, Pages 48: Comparison of DNA Extracted from Pediatric Saliva, Gingival Crevicular Fluid and Site-Specific Biofilm Samples Methods and Protocols doi: 10.3390/mps3030048 Authors: Jason Emett Roxanne David Jaydene McDaniel Steven McDaniel Karl Kingsley (1) Introduction: Due to the non-invasive nature of saliva, many methods have been used to isolate and collect DNA from saliva samples for microbial screening. Many oral microbes also inhabit the oral biofilm, which...
Thu Jul 09, 2020
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