New England Journal of Medicine, Ahead of Print.
Wed Jul 08, 2020 12:01
New England Journal of Medicine, Ahead of Print.
Wed Jul 08, 2020 12:01
New England Journal of Medicine, Ahead of Print.
Wed Jul 08, 2020 12:00
New England Journal of Medicine, Ahead of Print.
Wed Jul 08, 2020 12:00
New England Journal of Medicine, Ahead of Print.
Wed Jul 08, 2020 12:00
New England Journal of Medicine, Volume 383, Issue 2, Page 193-194, July 2020.
Wed Jul 08, 2020 11:55
New England Journal of Medicine, Volume 383, Issue 2, Page 97-99, July 2020.
Wed Jul 08, 2020 11:55
New England Journal of Medicine, Volume 383, Issue 2, Page 184-185, July 2020.
Wed Jul 08, 2020 11:55
New England Journal of Medicine, Volume 383, Issue 2, Page 180-181, July 2020.
Wed Jul 08, 2020 11:55
New England Journal of Medicine, Volume 383, Issue 2, Page 141-150, July 2020.
Wed Jul 08, 2020 11:55
New England Journal of Medicine, Volume 383, Issue 2, Page 99-101, July 2020.
Wed Jul 08, 2020 11:55
New England Journal of Medicine, Volume 383, Issue 2, Page 169-169, July 2020.
Wed Jul 08, 2020 11:55
New England Journal of Medicine, Volume 383, Issue 2, July 2020.
Wed Jul 08, 2020 11:55
New England Journal of Medicine, Volume 383, Issue 2, July 2020.
Wed Jul 08, 2020 11:55
New England Journal of Medicine, Volume 383, Issue 2, Page 109-119, July 2020.
Wed Jul 08, 2020 11:55
New England Journal of Medicine, Volume 383, Issue 2, Page 151-158, July 2020.
Wed Jul 08, 2020 11:55
New England Journal of Medicine, Volume 383, Issue 2, Page 129-140, July 2020.
Wed Jul 08, 2020 11:55
New England Journal of Medicine, Volume 383, Issue 2, July 2020.
Wed Jul 08, 2020 11:55
New England Journal of Medicine, Volume 383, Issue 2, Page 159-168, July 2020.
Wed Jul 08, 2020 11:55
Among older Americans, falls are the leading cause of injury-related deaths. Approximately one in four older adults falls each year, and 20 to 30% of those who fall have moderate-to-severe injuries, resulting in approximately 30,000 deaths, 3 million emergency department visits, and 800,000…
Thu Jul 09, 2020 03:00
The inflammatory skin condition atopic dermatitis is a chronic, relapsing disease characterized by epidermal-barrier disruption, T-cell activation, and imbalance of the skin microbiome. The pathogenesis of atopic dermatitis is primarily driven by type 2 helper T (Th2) lymphocytes, with considerable…
Thu Jul 09, 2020 03:00
Up to 2% of all cases of amyotrophic lateral sclerosis (ALS) result from mutations in the gene encoding superoxide dismutase 1 (SOD1). More than 180 different SOD1 mutations have been identified in ALS. Disease penetration, progression rate, and prognosis are variable and may be mutation-specific.…
Thu Jul 09, 2020 03:00
In 10% of patients with amyotrophic lateral sclerosis (ALS), the disease is hereditary and is caused by single-gene mutations. In animal models of familial ALS resulting from mutations in the gene encoding superoxide dismutase 1 (SOD1), suppression of the mutated gene increases survival. In…
Thu Jul 09, 2020 03:00
Households and other close-contact settings such as dormitories and schools are important sites for seasonal and pandemic transmission of influenza virus. School-age children often introduce the virus into households, with subsequent spread to younger siblings and adults. Adherence to…
Wed Jul 08, 2020 03:00
Degenerative cervical spondylosis is a chronic, progressive deterioration of osseocartilaginous components of the cervical spine that is most often related to aging. Radiographic evidence of degeneration of the cervical spine occurs in virtually all persons as they age; however, not all persons…
Thu Jul 09, 2020 03:00
Amyotrophic lateral sclerosis (ALS) is a heterogeneous disorder of progressive degeneration of upper and lower motor neurons that typically leads to death from ventilatory failure within 5 years after the onset of illness. Genetic factors account for half of the variance in the risk of the…
Thu Jul 09, 2020 03:00
Each year in the United States, approximately 120,000 people with kidney failure choose to start dialysis therapy — an arduous, life-sustaining treatment — and more than half a million patients already receiving dialysis continue their treatment. More than 80% of these patients receive hemodialysis…
Thu Jul 09, 2020 03:00
To many physicians who see patients with illnesses that are strongly influenced by social circumstances, socially oriented interventions make sense. The ideas behind such interventions are not new — community-oriented primary care in the United States has always had a strong focus on social rather…
Thu Jul 09, 2020 03:00
To the Editor: Nearly 70,000 people in the United States die each year from a drug overdose. Opioid-involved overdose deaths may be preventable by the timely administration of naloxone. Eleven countries have responded to health concerns regarding people who use drugs by opening sanctioned safe…
Wed Jul 08, 2020 03:00
I am standing in the Covid-19 respiratory clinic, wearing a gown and a mask and a face shield, and I’m bending over the exam table, earnestly wiping it down with gloved hands and sanitizing wipes. I’m taking care as if my life depends on it, because it does, and so does the life of the next patient…
Wed Jul 08, 2020 03:00
A 41-year-old farmer presented to the outpatient infectious disease clinic with a 20-year history of slowly growing lesions on the right leg that had progressed over time to cause gait abnormality. The lesions initially began as painless, pruritic papules on the knee and gradually spread to the…
Thu Jul 09, 2020 03:00
In late March, my mother and I were having our routine Covid-19–era argument about my upcoming clinical duties. She said I was acting like a teenager. I said she was treating me like one. "What if you end up on a ventilator?" she asked. "I live or I die," I said. She was silent. It was not my…
Thu Jul 09, 2020 03:00
Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in humans is associated with a broad spectrum of clinical respiratory syndromes, ranging from mild upper airway symptoms to progressive life-threatening viral pneumonia. Clinically, patients with severe coronavirus disease…
Thu Jul 09, 2020 03:00
The SARS-CoV-2 pandemic has inspired new interest in understanding the fundamental pathology of acute respiratory distress syndrome (ARDS), which has been associated with severe coronavirus disease 2019 (Covid-19). ARDS has long been recognized to be remarkably heterogeneous, with not only a wide…
Thu Jul 09, 2020 03:00
To the Editor: Annual influenza vaccination is recommended in young children. Preventive care visits, which often occur near a child’s birthday, are a convenient time to administer vaccines. Children who have their birthday — and thus their recommended yearly visit — before the vaccine becomes…
Thu Jul 09, 2020 03:00
Presentation of Case. Dr. Kathy M. Tran: A 76-year-old woman was admitted to this hospital because of confusion and hypoxemia during the pandemic of coronavirus disease 2019 (Covid-19), the disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The patient had been well…
Wed Jul 08, 2020 03:00
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