Decline in muscle strength and performance predicts fracture risk in elderly women and men. J Clin Endocrinol Metab. 2020 Jul 08;: Authors: Alajlouni D, Bliuc D, Tran T, Eisman JA, Nguyen TV, Center JR Abstract CONTEXT: Muscle strength and performance are associated with fractures. However, the contribution of their rate of decline is unclear. OBJECTIVE: To assess the independent contribution of the rate of decline in muscle strength...
Thu Jul 09, 2020 16:18
Primary care provider involvement in thyroid cancer survivorship care. J Clin Endocrinol Metab. 2020 Jul 08;: Authors: Radhakrishnan A, Reyes-Gastelum D, Gay B, Hawley ST, Hamilton AS, Ward KC, Wallner LP, Haymart MR Abstract OBJECTIVE: To understand PCP involvement and confidence in thyroid cancer survivorship care. DESIGN/: Setting/Participants: We surveyed PCPs identified by thyroid cancer patients from the Georgia and LA SEER registries...
Thu Jul 09, 2020 16:18
Related Articles Use of intrathecal chloroprocaine for ambulatory perianal procedures in the prone jackknife position: a retrospective single-center experience. Reg Anesth Pain Med. 2020 Jul 06;: Authors: Sanoja IA, Toth K, Ragheb-Mueller N PMID: 32636296 [PubMed - as supplied by publisher]
Thu Jul 09, 2020 16:23
Related Articles Semispinalis capitis muscle is a key factor in defining cervical nerve block effect. Reg Anesth Pain Med. 2020 Jul 06;: Authors: Ohgoshi Y PMID: 32636295 [PubMed - as supplied by publisher]
Thu Jul 09, 2020 16:23
Related Articles Novel cervical erector spinae plane block: interfascial layers remain important in the spread of anesthetics. Reg Anesth Pain Med. 2020 Jul 06;: Authors: Tsui BCH, Elsharkawy H PMID: 32636294 [PubMed - as supplied by publisher]
Thu Jul 09, 2020 16:23
Related Articles Investigating Influences of Medial Olivocochlear Efferent System on Central Auditory Processing and Listening in Noise: A Behavioral and Event-Related Potential Study. Brain Sci. 2020 Jul 04;10(7): Authors: Rao A, Koerner TK, Madsen B, Zhang Y Abstract This electrophysiological study investigated the role of the medial olivocochlear (MOC) efferents in listening in noise. Both ears of eleven normal-hearing adult participants...
Thu Jul 09, 2020 16:50
Related Articles Neural signatures of temporal regularity processing in sounds differ between younger and older adults. Neurobiol Aging. 2019 11;83:73-85 Authors: Herrmann B, Buckland C, Johnsrude IS Abstract Sensitivity to temporal regularity (e.g., recurring modulation in amplitude) is crucial for speech perception. Degradation of the auditory periphery due to aging and hearing loss may lead to increased responsiveness to sound in the auditory...
Thu Jul 09, 2020 16:50
Related Articles Versatility of the Supraclavicular Flap in Head and Neck Reconstruction. Eplasty. 2020;20:e7 Authors: de Carvalho FM, Correia B, Silva Á, Costa J Abstract Objective: Head and neck oncologic resections often leave intricate defects whose reconstruction remains a challenge. The pedicled supraclavicular artery perforator flap is an emerging option, and its applicability in head and neck reconstruction is gaining popularity....
Thu Jul 09, 2020 15:54
Related Articles Faster Healing and a Lower Rate of Recurrence of Venous Ulcers Treated With Intermittent Pneumatic Compression: Results of a Randomized Controlled Trial. Eplasty. 2020;20:e6 Authors: Alvarez OM, Markowitz L, Parker R, Wendelken ME Abstract Objective: Fifty-two subjects with chronic venous insufficiency and hard-to-heal lower leg ulceration (>1-year-old and >20-cm2 surface area) were treated with either intermittent,...
Thu Jul 09, 2020 15:54
Related Articles [The role of surgery and salvage surgery in the era of HPV-associated oropharyngeal carcinomas]. HNO. 2020 Jul 07;: Authors: Hussain T, Mattheis S, Lang S Abstract The incidence of human papillomavirus (HPV)-positive oropharyngeal carcinomas is increasing worldwide. Due to a markedly different response to treatment compared to HPV-negative oropharyngeal carcinomas, determining the ideal therapeutic approach can be challenging....
Thu Jul 09, 2020 13:09
Related Articles Development of a smartphone app for neuromuscular facial training. HNO. 2020 Jul 07;: Authors: Taeger J, Bischoff S, Hagen R, Rak K Abstract BACKGROUND: Several studies have demonstrated a significant benefit of neuromuscular facial training in the rehabilitation of patients with facial palsy. However, printed instructions for home training are often not of optimum quality and associated with low adherence to therapy. Professional...
Thu Jul 09, 2020 13:09
The Prolyl Hydroxylase Inhibitor Dimethyl Oxalyl Glycine Decreases Early Gastrointestinal GVHD in Experimental Allogeneic Hematopoietic Cell Transplantation. Transplantation. 2020 Jun 29;: Authors: Palaniyandi S, Kumari R, Radhakrishnan SV, Strattan E, Hakim N, Munker R, Kesler MV, Hildebrandt GC Abstract BACKGROUND: Prolyl hydroxylase inhibitors (PHI) promote stabilization of hypoxia-inducible factor-1 alpha (HIF-1α) and affect signaling cascades...
Thu Jul 09, 2020 17:04
An artefact-resist optrode with internal shielding structure for low-noise neural modulation. J Neural Eng. 2020 Jul 08;: Authors: Wang L, Ge C, Wang M, Ji B, Guo Z, Wang X, Yang B, Li C, Liu J Abstract OBJECTIVE: The combination of optical manipulation of neural activities with electrophysiology recording is a promising technology for discovering mechanisms of brain disorders and mapping brain networks. However, fiber-based optrode is limited...
Thu Jul 09, 2020 14:41
Related Articles Robotic thyroid surgery. Auris Nasus Larynx. 2020 Jul 04;: Authors: Tae K Abstract Various remote access robotic thyroidectomy techniques have been developed using the da Vinci® surgical system (Intuitive Surgical Inc., Sunnyvale, CA) to hide or avoid neck scarring and overcome the limitations of endoscopic thyroidectomy. Among those used today are the gasless transaxillary approach, the bilateral axillo-breast approach (BABA),...
Thu Jul 09, 2020 14:07
Related Articles Can we palpate cricothyroid membrane in children accurately? Paediatr Anaesth. 2020 05;30(5):629 Authors: Ankay Yilbas A, Basaran B PMID: 32500965 [PubMed - indexed for MEDLINE]
Thu Jul 09, 2020 14:07
Related Articles Forestier Disease and Airway Management. Anesthesiology. 2020 04;132(4):898 Authors: Fujii M, Sugiyama D, Ueda K, Kobayashi O PMID: 31972658 [PubMed - indexed for MEDLINE]
Thu Jul 09, 2020 14:07
Related Articles The distance between the glottis and the cuff of a tracheal tube placed through three supraglottic airway devices in children: A randomised controlled trial. Eur J Anaesthesiol. 2019 Oct;36(10):721-727 Authors: Lee JH, Park S, Jang YE, Kim EH, Kim HS, Kim JT Abstract BACKGROUND: After tracheal tube insertion via various types of supraglottic airway devices, the distance from the tube cuff to the vocal cords has not been evaluated...
Thu Jul 09, 2020 14:07
Related Articles Unique Bone Suture Anchor Repair of Complex Lumbar Cerebrospinal Fluid Fistulas. Surg Neurol Int. 2020;11:153 Authors: Agulnick M, Cohen BR, Epstein NE Abstract Background: Spine surgeons encounter occasional complex cerebrospinal fluid fistulas/dural tears (CSF/DT) during lumbar spinal surgery. In some cases, these leaks are found during the index procedure, but others may appear postoperatively, or in the course of successive...
Thu Jul 09, 2020 14:49
Related Articles Spontaneous intracranial hypotension due to sacral diverticula: Two-case history and a pocket-sized review. Neurocirugia (Astur). 2019 Sep - Oct;30(5):228-232 Authors: Cultrera F, Lofrese G, Nasi MT Abstract Spontaneous intracranial hypotension is an increasingly recognized cause of atypical, secondary headaches. Nevertheless, its clinical and imaging spectrum is far from an exhaustive definition, ranging from straightforward...
Thu Jul 09, 2020 14:49
Stress and Perception of Procedural Pain Management in Chinese Parents of Children with Cancer. J Pain Symptom Manage. 2020 Jul 05;: Authors: Yan C, Cheung R, Lee Wong C, Cheng HY, Liu F, Huang H, Ewig C, Li CK, Zhang H, Cheung YT Abstract OBJECTIVES: Children with cancer are exposed to repeated painful and invasive procedures. This study examines Chinese parents' stress and perception towards their children's procedural pain-control. ...
Thu Jul 09, 2020 13:11
T-cell receptor therapy (TCR) against melanoma -immunotherapy for the future? Scand J Immunol. 2020 Jul 08;:e12927 Authors: Winge-Main AK, Wälchli S, Marit Inderberg E Abstract Malignant melanoma has seen monumental changes in treatment-options the last decade from the very poor results of dacarbazine treatment to the modern-day use of targeted therapies and immune checkpoint inhibitors. Melanoma has a high mutational burden making it more...
Thu Jul 09, 2020 13:11
Broadening Eligibility Criteria for Oncology Clinical Trials: Current Advances and Future Directions. Clin Pharmacol Ther. 2020 Jul 08;: Authors: Rahman NA, Ison G, Beaver JA PMID: 32640034 [PubMed - as supplied by publisher]
Thu Jul 09, 2020 13:11
LncRNA AGAP2-AS1 accelerates cell proliferation, migration, invasion and EMT process in colorectal cancer via regulating miR-4668-3p/SRSF1 axis. J Gene Med. 2020 Jul 08;:e3250 Authors: Li H, Guo S, Zhang M, Li L, Wang F, Song B Abstract BACKGROUND: Colorectal cancer (CRC) is a frequently occurring tumor. Although a number of long noncoding RNAs (lncRNAs) have been researched in CRC, the expression, function and mechanism of AGAP2-AS1 remains...
Thu Jul 09, 2020 13:11
The benefit of prehabilitation and enhanced recovery in robot-assisted radical prostatectomy and the promising future of these protocols in the field of urologic oncology. Cancer. 2020 Jul 08;: Authors: Townsend WB, Worrilow WM, Riggs SB PMID: 32639580 [PubMed - as supplied by publisher]
Thu Jul 09, 2020 13:11
Calcium channel blockers in pancreatic cancer: increased overall survival in a retrospective cohort study. Anticancer Drugs. 2020 Jul 03;: Authors: Tingle SJ, Severs GR, Moir JAG, White SA Abstract Repurposing commonly prescribed noncancer medications for use in oncology has substantial advantages over de-novo development of anticancer drugs. Calcium signalling has been implicated in many of the hallmarks of cancer. Previous in-vitro and in-vivo...
Thu Jul 09, 2020 13:11
Comprehensive analysis of multiple parameters associated with tumor immune microenvironment in ARID1A mutant cancers. Future Oncol. 2020 Jul 08;: Authors: Li Z, Lin J, Zhang L, Li J, Zhang Y, Zhao C, Wang H Abstract Aim: To verify the relationship between ARID1A and tumor immune microenvironment thus immune checkpoint inhibitors (ICIs) response. Material & methods: Several public databases were used to characterize the association between...
Thu Jul 09, 2020 13:11
Recent advances in inhibitors of C-terminal SRC kinase. Future Med Chem. 2020 Jul 08;: Authors: P O'Malley D PMID: 32638626 [PubMed - as supplied by publisher]
Thu Jul 09, 2020 13:11
Related Articles Chromosome Abnormalities: New Insights into Their Clinical Significance in Cancer. Mol Ther Oncolytics. 2020 Jun 26;17:562-570 Authors: Kou F, Wu L, Ren X, Yang L Abstract Chromosomal abnormalities, consisting of numerical and structural chromosome abnormalities, are a common characteristic of cancer. Numerical chromosome abnormalities, mainly including aneuploidy and chromosome instability, are caused by chromosome segregation...
Thu Jul 09, 2020 13:11
Related Articles Evolving treatment strategies of brain metastases from breast cancer: current status and future direction. Ther Adv Med Oncol. 2020;12:1758835920936117 Authors: Kim JS, Kim IA Abstract Remarkable progress in breast cancer treatment has improved patient survival, resulting in an increased incidence of brain metastasis (BM). Current treatment options for BM are limited and are generally used for palliative purposes. Historically,...
Thu Jul 09, 2020 13:11
Related Articles A phase II trial of tipifarnib for patients with previously-treated, metastatic urothelial carcinoma harboring HRAS mutations. Clin Cancer Res. 2020 Jul 07;: Authors: Lee HW, Sa JK, Gualberto A, Scholz C, Sung HH, Jeong BC, Choi HY, Kwon GY, Park SH Abstract PURPOSE: To assess the antitumor activity and safety of tipifarnib, a highly potent and selective farnesyltransferase inhibitor, we performed a phase II clinical trial in...
Thu Jul 09, 2020 13:11
Related Articles DNA Repair and Prostate Cancer: A Field Ripe for Harvest. Eur Urol. 2020 Jul 04;: Authors: Bryce AH, Sartor O, de Bono J Abstract Recent data have revealed antitumor activity for four PARP inhibitors, two of which (olaparib and rucaparib) are approved by the US Food and Drug Administration for metastatic castrate-resistant prostate cancer with selected DNA repair defects. Additional clinical trials are in progress for talazoparib,...
Thu Jul 09, 2020 13:11
Related Articles Emerging functions for ANKHD1 in cancer-related signaling pathways and cellular processes. BMB Rep. 2020 Jul 08;: Authors: Almeida BO, Machado-Neto JA Abstract ANKHD1 (ankyrin repeat and KH domain containing 1) is a large protein characterized by the presence of multiple ankyrin repeats and a K-homology domain. Ankyrin repeat domains consist of widely existing protein motifs in nature, they mediate protein-protein interactions...
Thu Jul 09, 2020 13:11
Related Articles JAK-Inhibitors for the Treatment of Rheumatoid Arthritis: A Focus on the Present and an Outlook on the Future. Biomolecules. 2020 Jul 05;10(7): Authors: Angelini J, Talotta R, Roncato R, Fornasier G, Barbiero G, Dal Cin L, Brancati S, Scaglione F Abstract Janus kinase inhibitors (JAKi) belong to a new class of oral targeted disease-modifying drugs which have recently revolutionized the therapeutic panorama of rheumatoid arthritis...
Thu Jul 09, 2020 13:11
Related Articles Resectability and Ablatability Criteria for the Treatment of Liver Only Colorectal Metastases: Multidisciplinary Consensus Document from the COLLISION Trial Group. Cancers (Basel). 2020 Jul 03;12(7): Authors: Nieuwenhuizen S, Puijk RS, van den Bemd B, Aldrighetti L, Arntz M, van den Boezem PB, Bruynzeel AME, Burgmans MC, de Cobelli F, Coolsen MME, Dejong CHC, Derks S, Diederik A, van Duijvendijk P, Eker HH, Engelsman AF, Erdmann JI, Fütterer...
Thu Jul 09, 2020 13:11
Related Articles Correction: Characterization of CDK(5) inhibitor, 20-223 (aka CP668863) for colorectal cancer therapy. Oncotarget. 2020 Jun 23;11(25):2462-2463 Authors: Robb CM, Kour S, Contreras JI, Agarwal E, Barger CJ, Rana S, Sonawane Y, Neilsen BK, Taylor M, Kizhake S, Thakare RN, Chowdhury S, Wang J, Black JD, Hollingsworth MA, Brattain MG, Natarajan A Abstract [This corrects the article DOI: 10.18632/oncotarget.23749.]. ...
Thu Jul 09, 2020 16:09
Related Articles Indoximod opposes the immunosuppressive effects mediated by IDO and TDO via modulation of AhR function and activation of mTORC1. Oncotarget. 2020 Jun 23;11(25):2438-2461 Authors: Brincks EL, Adams J, Wang L, Turner B, Marcinowicz A, Ke J, Essmann M, Mautino LM, Allen CV, Kumar S, Vahanian N, Link C, Mautino MR Abstract Indoximod has shaped our understanding of the biology of IDO1 in the control of immune responses, though...
Thu Jul 09, 2020 16:09
Related Articles Tumor suppressor p53 regulates insulin receptor (INSR) gene expression via direct binding to the INSR promoter. Oncotarget. 2020 Jun 23;11(25):2424-2437 Authors: Sarfstein R, Werner H Abstract A significant volume of clinical and epidemiological data provides support to the concept that insulin and the insulin receptor (INSR) have an important role in breast cancer. Tumor suppressor p53 is the most frequently mutated molecule...
Thu Jul 09, 2020 16:09
Related Articles Postoperative atrial fibrillation does not impact on overall survival after esophagectomy in patients with thoracic esophageal cancer: results from a randomized, double-blind, placebo-controlled trial. Oncotarget. 2020 Jun 23;11(25):2414-2423 Authors: Ojima T, Nakamura M, Hayata K, Kitadani J, Katsuda M, Nakamori M, Takeuchi A, Maruoka S, Fukuda N, Tominaga S, Motobayashi H, Yamaue H Abstract BACKGROUND: Administration...
Thu Jul 09, 2020 16:09
Related Articles Mutation profile of primary subungual melanomas in Caucasians. Oncotarget. 2020 Jun 23;11(25):2404-2413 Authors: Borkowska A, Szumera-Ciećkiewicz A, Spałek M, Teterycz P, Czarnecka A, Kowalik A, Rutkowski P Abstract BACKGROUND: Specific genomic profile of cutaneous melanomas is related to UVR exposure, which exerts biological and therapeutic impact. Subungual melanoma (SUM) is an exceedingly rare disease; therefore, it...
Thu Jul 09, 2020 16:09
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου