Publication date: Available online 11 September 2019Source: Revue des Maladies RespiratoiresAuthor(s): J. Taytard, P. Boizeau, C. Alberti, N. BeydonRésuméIntroductionLa capacité de transfert du monoxyde de carbone (DLCO) est mesurée par la méthode de référence durant une apnée (DLCOap) ou, en cas d’impossibilité d’obtenir une DCLOap, en respiration spontanée avec d’autres méthodes dont celle de la réinspiration (rebreathing ; rb). L’objectif était d’évaluer la faisabilité en clinique de la mesure...
Publication date: Available online 11 September 2019Source: Revue des Maladies RespiratoiresAuthor(s): M. Lemyze, M. GranierRésuméDu fait d’une épidémie toujours croissante, l’obésité morbide est devenue une maladie courante en soins critiques. Ses conséquences sur l’appareil respiratoire sont multiples, à la fois sur la mécanique et l’échangeur pulmonaire, et impactent considérablement la prise en charge et le pronostic. Les caractéristiques anatomiques et physiologiques respiratoires particulières...
Publication date: Available online 11 September 2019Source: Revue des Maladies RespiratoiresAuthor(s): D. FloretRésuméEn France, le ministre chargé de la santé est responsable de la politique vaccinale. Son élaboration repose sur l’expertise d’une Commission technique des vaccinations, rattachée à la Haute Autorité de santé (HAS). Ses missions sont d’émettre des recommandations et de proposer les mises à jour du calendrier vaccinal. Sa composition garantit une expertise pluridisciplinaire en intégrant...
Publication date: Available online 11 September 2019Source: Revue des Maladies RespiratoiresAuthor(s): A. Cuvelier, C. Taillé
Publication date: Available online 11 September 2019Source: Revue des Maladies RespiratoiresAuthor(s): R. Marouf, S. Hamraoui, I. AlloubiRésuméL’inhalation de corps étrangers (CE) trachéobronchiques est une urgence diagnostique nécessitant une extraction rapide du CE pour assurer une bonne récupération et minimiser les complications. C’est un accident qui survient le plus souvent chez les enfants et exceptionnellement chez l’adulte. Nous rapportons le cas d’un patient de 43 ans, admis pour un CE...
Publication date: Available online 11 September 2019Source: Revue des Maladies RespiratoiresAuthor(s): A. De Jong, D. Verzilli, G. Chanques, E. Futier, S. JaberRésuméLe patient obèse est à risque de complications péri-opératoires qui regroupent essentiellement l’accès difficile aux voies aériennes (intubation, ventilation difficile voire impossible), et les détresses respiratoires postextubation secondaires à la formation d’atélectasies ou à l’obstruction des voies aériennes, parfois associées à...
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This protocol presents a standardized method to grow VX2 cells in culture and to create an orthotopic VX2 model of endometrial cancer with retroperitoneal lymph node metastases in rabbits. Orthotopic endometrial cancer models are important for the pre-clinical study of novel imaging modalities for the diagnosis of lymph node metastases.
Here, we describe the development of a clinically relevant murine model of liver cancer recapitulating the typical immune features of hepatocellular cancer (HCC).
Method to assess the impact of training on motor skills is a useful tool. Unfortunately, most behavioral assessments can be labor intensive and/or expensive.We describe here a robotic method of assessing prehension (reach-to-grasp) skill in mice.
This protocol isolates extracellular vesicles (EVs) away from virions with high efficiency and yield by incorporating EV precipitation, density gradient ultracentrifugation, and particle capture to allow for a streamlined workflow and a reduction of starting volume requirements, resulting in reproducible preparations for use in all EV research.
Here, microbially induced calcite precipitation (MICP) technology is presented to improve soil properties by immersion.
In this study, we describe a detailed procedure of TNBS-mediated intestinal fibrosis, which exhibits comparable pathophysiology to Crohn's fibrosis. We also discuss this approach in light of rapamycin facilitated inhibitory effects on intestinal fibrosis.
We describe the application of infrared nanospectroscopy and high-resolution atomic force microscopy to visualize the process of protein self-assembly into oligomeric aggregates and amyloid fibrils, which is closely associated with the onset and development of a wide range of human neurodegenerative disorders.
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Life on Earth is amazingly diverse, and exhibits striking geographical global patterns in biodiversity. A pair of companion papers reveal that mountain regions -- especially those in the tropics -- are hotspots of extraordinary and baffling richness. Although mountain regions cover only 25% of Earth's land area, they are home to more than 85% of the world's species of amphibians, birds, and mammals, and many of these are found only in mountains.
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Abstract Purpose Evaluation of the utility of the free anterolateral thigh flap reconstruction of the defects resulting from radical temporal bone resection in the management of lateral skull base malignancies in a single institution. Methods An analysis of 17 en bloc subtotal petrosectomies for removal of malignant tumours was performed. There were 12 squamous...
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Publication date: Available online 11 September 2019Source: Acta Otorrinolaringológica EspañolaAuthor(s): Patrícia Gomes, Pedro Salvador, Catarina Lombo, Sérgio Caselhos, Rui FonsecaAbstractObjectiveEpistaxis is one of the commonest causes of attendance of Otolaryngology emergency rooms. Given its incidence, potential severity and high recurrence rate, a systematic and careful management is mandatory. This work aims to define prognostic factors of epistaxis recurrence.Material and methodsRetrospective...
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Abstract Purpose: To investigate the effect of astragaloside IV (As-IV) on myocardial ischemia-reperfusion (I/R) injury in rats and reltaed mechanisms. Methods: Sixty rats were randomly divided into sham-operated, control I/R and 2.5, 5 and 10 mg/kg As-IV groups, 12 rats in each group. The later three groups were intragastrically administered with As-IV for 7 days, with a dose of 2.5, 5 and 10 mg/kg, respectively. The myocardial I/R injury model was constructed in later four groups. At the end...
Abstract Purpose: To investigate the protective roles of pyracantha fortune fruit extract (PFE) on acute renal toxicity induced by cadmium chloride (CdCl2) in rats. Methods: Rats were pretreated with PFE and consecutively injected with CdCl2 (6.5 mg/kg) for 5 days. Results: The concentration of Cd, kidney weight, malondialdehyde (MDA), and nitric oxide (NO) production were remarkably increased in CdCl2 group as well as the levels of plasma uric acid, urea, and creatinine (P < 0.001). However,...
Abstract Purpose: The effects of resveratrol administration on calvarial bone defects with alloplastic graft material was investigated for osteoinductive reaction and bone development in rats. Methods: Healthy male rats were randomly divided into 3 groups consisting of 10 rats. Groups were as follows: control (defect) group, defect + graft group, and defect + graft + resveratrol group. A calvarial bone defect was created in all groups, alloplastic bone grafts were applied to the defect in the 2nd...
Abstract Purpose: To compare four types of mesh regarding visceral adhesions, inflammatory response and incorporation. Methods: Sixty Wistar rats were divided into four groups, with different meshes implanted intraperitoneally: polytetrafluoroethylene (ePTFE group); polypropylene with polydioxanone and oxidized cellulose (PCD); polypropylene (PM) and polypropylene with silicone (PMS). The variables analyzed were: area covered by adhesions, incorporation of the mesh and inflammatory reaction (evaluated...
Abstract Purpose: To investigate the effect of intermittent vibration at different intervals on bone fracture healing and optimize the vibration interval. Methods: Ninety sheep were randomized to receive no treatment (the control group), incision only (the sham control group), internal fixation with or without metatarsal fracture (the internal fixation group), and continuous vibration in addition to internal fixation of metatarsal fracture, or intermittent vibration at 1, 2, 3, 5, 7 and 17-day...
Abstract Purpose: To compare the use of new cyanoacrylate surgical adhesive associated with macroporous tapes in cutaneous synthesis. Methods: Male Wistar rats with a longitudinal incision of 4cm were used on the back, divided into four groups: GI used octyl-cyanoacrylate (Dermabond®), GII used N-2-butylcyanoacrylate, GIII used octyl-cyanoacrylate and macroporous tape and GIV used N-2-butyl cyanoacrylate and macroporous tape. On the fourteenth day, the rats were submitted to euthanasia, were divided...
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Asthma and hypertension are common chronic diseases, each with attendant morbidity, mortality, and economic effects. It is estimated that 300 million people worldwide have asthma, and an increase in prevalence to 400 million is anticipated by 2025. Approximately 250,000 asthma-related deaths occur…
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An international team of scientists has solved a centuries-old mystery of 'Fraser's Clawed Frog', an unusual and elusive species found in West Africa.
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RESUMO Objetivo Verificar os efeitos de uma estratégia de aquecimento (AV) e desaquecimento vocal (DV) em professores. Método Estudo exploratório quase-experimental, cego ao avaliador, com grupo controle composto por professores de uma escola pública de ensino médio. Os professores, alocados no grupo experimental (GE), realizaram AV prévio e DV posterior à aula. Os professores do grupo controle (GC) não realizaram AV prévio e ficaram em repouso vocal após a aula. Compararam-se os dados intergrupos...
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Abstract Background The management of chronic urticaria (CU) has been controversial. Recently updated international guidelines propose evidence‐based diagnosis and treatment. Nevertheless, dermatologists have heterogeneous approaches to managing CU. Purpose To estimate the percentage of dermatologists who have an optimal approach to CU according to the international guidelines, and to explore the variables associated with optimal management. Method A cross‐sectional study using a...
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Journal of International Medical Research, Ahead of Print.
Journal of International Medical Research, Ahead of Print.
Journal of International Medical Research, Ahead of Print.
Journal of International Medical Research, Ahead of Print.
Journal of International Medical Research, Ahead of Print.
Journal of International Medical Research, Ahead of Print.
Journal of International Medical Research, Ahead of Print.
Journal of International Medical Research, Ahead of Print.
Journal of International Medical Research, Ahead of Print.
Journal of International Medical Research, Ahead of Print.
Journal of International Medical Research, Ahead of Print.
Journal of International Medical Research, Ahead of Print.
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