Related ArticlesGeneration of craniofacial myogenic progenitor cells from human induced pluripotent stem cells for skeletal muscle tissue regeneration. Biomaterials. 2020 Apr 02;248:119995 Authors: Kim E, Wu F, Wu X, Choo HJ Abstract Craniofacial skeletal muscle is composed of approximately 60 muscles, which have critical functions including food uptake, eye movements and facial expressions. Although craniofacial muscles have significantly different...
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Related ArticlesRole of SUMOylation in Human Oncogenic Herpesvirus Infection. Virus Res. 2020 Apr 10;:197962 Authors: Zhang Y, Wang Y, Zhu C, Robertson ES, Cai Q Abstract Post-translational modification of target proteins by the Small Ubiquitin-like Modifier (SUMO) plays a critical role in regulation of many cellular processes including transcription, RNA processing, protein trafficking, DNA repair, and chromosome segregation, and is also often hijacked...
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Related ArticlesReconstruction of Through-and-Through Composite Segmental Mandibulectomy Defect in a Patient With a Dominant Peroneal Artery Using an Anterior Lateral Thigh Osteomyocutaneous Free Flap: A Case Report and Description of Flap. J Oral Maxillofac Surg. 2020 Mar 15;: Authors: Shanti RM, Choi J, Thomas WW, Sheth NP, Cannady SB Abstract The anterior lateral thigh osteomyocutaneous (ALTO) free flap represents a unique reconstructive option...
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Related ArticlesCheckpoint inhibitors: Better outcomes among advanced cutaneous head and neck melanoma patients. PLoS One. 2020;15(4):e0231038 Authors: Hirshoren N, Yoeli R, Cohen JE, Weinberger JM, Kaplan N, Merims S, Peretz T, Lotem M Abstract OBJECTIVE: The aim of this study was to investigate if the treatment outcomes of checkpoint inhibitors (CPI) in patients with advanced-stage skin head and neck melanoma (HNM) differs from outcomes in patients...
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Related ArticlesThe Use of a Novel, Nonsurgical Bone Conduction Hearing Aid System for the Treatment of Conductive Hearing Loss. Otol Neurotol. 2020 Apr 10;: Authors: Kuthubutheen J, Broadbent C, Marino R, Távora-Vieira D Abstract OBJECTIVE: Conventional bone conduction hearing aid solutions often require a cumbersome retention system such as a headband or cap. This study aims to determine if a novel, nonsurgical bone conduction aid utilizing an...
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Related ArticlesSubjective and Objective Effectiveness of Eustachian Tube Balloon Dilatation for Patients With Eustachian Tube Dysfunction-Evaluation in a Pressure Chamber. Otol Neurotol. 2020 Apr 10;: Authors: Jansen S, Peters N, Hinkelbein J, Klußmann JP, Beutner D, Meyer MF Abstract INTRODUCTION: The Eustachian tube plays a crucial role in pressure equalization between the middle ear and ambient pressure for fast and large pressure differences....
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Related ArticlesDo Postoperative Antibiotics Improve Skin Reactivity Following Percutaneous Auditory Osseointegrated Implant Placement? Otol Neurotol. 2020 Apr 10;: Authors: Kazi AA, Howell JB, Shaia WT, Coelho DH Abstract OBJECTIVE: To determine if the routine use of postoperative antibiotics following percutaneous auditory osseointegrated implant placement reduces skin reactivity. STUDY DESIGN: Retrospective matched case-controlled series....
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Related ArticlesClinicopathologic characteristics and outcomes of papillary thyroid carcinoma in younger patients. Medicine (Baltimore). 2020 Apr;99(15):e19795 Authors: Lu Y, Jiang L, Chen C, Chen H, Yao Q Abstract In the 7th edition of AJCC staging system, cervical lymph node metastases (LNM) in papillary thyroid carcinoma (PTC) is considered as a poorer prognostic indicator only in patients aged 45 years or older, but as a low-risk factor in patients...
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Related ArticlesApplication of multiple injections of contrast agent in head and neck CT arteriovenous angiography in children: Study protocol clinical trial (SPIRIT Compliant). Medicine (Baltimore). 2020 Apr;99(15):e19773 Authors: Tang S, Zhang G, Chen Z, Liu X, Fan X, Liu D, He L Abstract OBJECTIVE: To investigate the application value of multiple injections of contrast agent in head and neck CT arteriovenous angiography in children. ...
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Related ArticlesTraumatic Brain Injury in Trauma Patients With Isolated Facial Fractures. J Craniofac Surg. 2020 Apr 07;: Authors: McCarty JC, Kiwanuka E, Gadkaree S, Siu JM, Caterson EJ Abstract BACKGROUND: Diagnosis of traumatic brain injury (TBI), and specifically mild TBI (mTBI), is a diagnostic challenge which can delay diagnosis preventing early intervention and follow-up care. Facial fractures represent an objective surrogate marker for potential...
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Related ArticlesOpen Versus Closing Wedge Osteotomy and Application to Mandibular Reconstruction. J Craniofac Surg. 2020 Apr 07;: Authors: Hu S, Klimczak J, Garner W, Hart H, Kadakia SP, Wood-Smith D, Abraham MT Abstract PURPOSE: To review the specific techniques of closing wedge osteotomy and open osteotomy, compare their clinical and radiographic outcomes, and apply these findings to mandibular reconstruction. METHODS: A thorough review...
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Related ArticlesMalignant Mixed Tumor (Carcinoma Ex Pleomorphic Adenoma) of the Lacrimal Gland. Ophthalmic Plast Reconstr Surg. 2020 Apr 08;: Authors: Tom A, Bell D, Ford JR, Debnam JM, Guo Y, Frank SJ, Esmaeli B Abstract PURPOSE: To review the clinical presentation, treatment, and prognosis of patients with malignant mixed tumor (carcinoma ex pleomorphic adenoma) of the lacrimal gland. METHODS: Clinical records and radiographic images...
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Related ArticlesShikonin inhibits growth, invasion and glycolysis of nasopharyngeal carcinoma cells through inactivating the phosphatidylinositol 3 kinase/AKT signal pathway. Anticancer Drugs. 2020 Apr 08;: Authors: Zhang J, Zhou J, Xiao S Abstract Nasopharyngeal carcinoma (NPC) is a malignant tumor which is commonly found in East Asia and Africa. The present clinical treatment of NPC is still mainly based on chemotherapeutics and is prone to drug...
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Related ArticlesAdverse Surgical Events: Effects on the Surgeon. Ear Nose Throat J. 2020 May;99(4):225-226 Authors: Sataloff RT PMID: 32282244 [PubMed - as supplied by publisher]
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Related ArticlesThe Health Utility and Valuation of Cosmetic Rhinoplasty. Facial Plast Surg Aesthet Med. 2020 Apr 13;: Authors: Kumar AR, Ishii M, Papel I, Kontis T, Liao D, Chen J, Ishii LE Abstract Importance: The importance of this study is to understand the impact of rhinoplasty as perceived by society and to conceptualize the health utility metric of cosmetic rhinoplasty in relation to other health interventions. Objective: This novel study...
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Related ArticlesOlfactory dysfunction from acute upper respiratory infections: relationship to season of onset. Int Forum Allergy Rhinol. 2020 Apr 13;: Authors: Potter MR, Chen JH, Lobban NS, Doty RL Abstract BACKGROUND: Acute viral upper respiratory tract infections are the most common cause of chronic olfactory dysfunction. In light of the seasonality of numerous viruses, the question arises as to whether the frequency and magnitude of postviral...
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Related ArticlesUnderstood? Evaluating the readability and understandability of intranasal corticosteroid delivery instructions. Int Forum Allergy Rhinol. 2020 Apr 13;: Authors: Lee SE, Brown WC, Gelpi MW, Kimple AJ, Senior BA, Zanation AM, Thorp BD, Ebert CS Abstract BACKGROUND: Allergic rhinitis is a widespread disease that has significant quality-of-life ramifications. Symptoms include rhinorrhea, nasal obstruction, cough, and postnasal drip....
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Related ArticlesEffectiveness of using a bioabsorbable implant (Latera) to treat nasal valve collapse in patients with nasal obstruction: systemic review and meta-analysis. Int Forum Allergy Rhinol. 2020 Apr 13;: Authors: Kim DH, Lee HH, Kim SH, Hwang SH Abstract BACKGROUND: Nasal obstruction is a common cause of breathing problems with lateral wall insufficiency (LWI) a key anatomic contributor. Recently, a bioabsorbable nasal implant was introduced...
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Related ArticlesThe management of periorbital cellulitis secondary to sinonasal infection: a multicenter prospective study in the United Kingdom. Int Forum Allergy Rhinol. 2020 Apr 13;: Authors: Mahalingam S, Hone R, Lloyd G, Grounds R, Shamil E, Wong G, Al-Lami A, Pervez A, Rudd J, Poon JS, Riley P, Hopkins C Abstract BACKGROUND: Periorbital cellulitis is a potential sight-threatening complication of sinusitis. The majority of patients improve with...
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Related ArticlesQuality and Readability Assessment of Websites on Human Papillomavirus and Oropharyngeal Cancer. Laryngoscope. 2020 Apr 13;: Authors: Schwarzbach HL, Mady LJ, Kaffenberger TM, Duvvuri U, Jabbour N Abstract OBJECTIVES/HYPOTHESIS: The incidence of human papillomavirus-positive (HPV+) oropharyngeal cancer is rising, but public knowledge about this diagnosis remains low. This study aimed to investigate the quality and readability of online...
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Related ArticlesA Method for Generating Intensity Modulated Radiation Therapy Fields for Small Animal Irradiators Utilizing 3D Printed Compensator Molds. Med Phys. 2020 Apr 13;: Authors: Yoon SW, Kodra J, Miles DA, Kirsch DG, Oldham M Abstract PURPOSE: The purpose of this study was to investigate the feasibility of using fused deposition modeling (FDM) 3D-printer to generate radiation compensators for high-resolution (~1mm) intensity modulated radiation...
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Related ArticlesSLEEP-GOAL: A multicenter success criteria outcome study on 302 obstructive sleep apnoea (OSA) patients. Med J Malaysia. 2020 Mar;75(2):117-123 Authors: Pang KP, Baptista PM, Olszewska E, Braverman I, Carrasco-Llatas M, Kishore S, Chandra S, Yang HC, Chan YH, Pang KA, Pang EB, Rotenberg B Abstract OBJECTIVE: To demonstrate SLEEP-GOAL as a more holistic and comprehensive success criterion for Obstructive Sleep Apnoea (OSA) treatment....
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Related ArticlesManagement of epistaxis in patients on novel oral anticoagulation therapy. J Laryngol Otol. 2020 Apr 13;:1-7 Authors: Ho JPK, Bari N, Riffat F Abstract BACKGROUND: Individuals on anticoagulation therapy are at increased risk of bleeding, including epistaxis. There is a lack of available reversal agents for novel oral anticoagulation therapy. OBJECTIVE: This paper reviews the current literature on epistaxis in the context...
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Related ArticlesFirst Reported Cochlear Implantation in a Child with Total Artificial Heart. Exp Clin Transplant. 2020 Apr 07;: Authors: Büyükatalay ZÇ, Agha Oghali AMN, Kendirli T, Can ÖS, Uçar T, Akar AR, Meço C Abstract We report a case of 15-year-old boy with postlingual bilateral total hearing loss following ototoxic medication during his pediatric intensive care unit stay. The patient received the SynCardia total artificial heart implant (50...
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Related ArticlesThe Landscape of CD28, CD80, CD86, CTLA4, and ICOS DNA Methylation in Head and Neck Squamous Cell Carcinomas. Epigenetics. 2020 Apr 11;: Authors: de Vos L, Grünwald I, Bawden EG, Dietrich J, Scheckenbach K, Wiek C, Zarbl R, Bootz F, Landsberg J, Dietrich D Abstract CTLA-4 blocking therapeutic antibodies are currently under investigation in head and neck squamous cell carcinoma (HNSCC). A better understanding of the epigenetic regulation...
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Related ArticlesIs it Usher syndrome? Collaborative diagnosis and molecular genetics of patients with visual impairment and hearing loss. Ophthalmic Genet. 2020 Apr 13;:1-8 Authors: Stiff HA, Sloan-Heggen CM, Ko A, Pfeifer WL, Kolbe DL, Nishimura CJ, Frees KL, Booth KT, Wang D, Weaver AE, Azaiez H, Kamholz J, Smith RJH, Drack AV Abstract Background: Usher syndrome is the most common hereditary syndrome combining deafness and blindness. In the 2017...
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Related ArticlesPost-tonsillectomy hemorrhage: cost-benefit analysis of prolonged hospitalization. Acta Otolaryngol. 2020 Apr 11;:1-6 Authors: Vyskocil E, Baumgartner WD, Ch Grasl M, Grasl S, Arnoldner C, Steyrer J, Erovic BM Abstract Background: Prolonged hospitalization after tonsillectomy up to three nights was implemented to decrease mortality due to post-tonsillectomy hemorrhage.Aims: To assess if extension of postoperative inpatient observation...
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Related ArticlesPhonophobia and migraine features in patients with definite meniere's disease: Pentad or triad/tetrad? Acta Otolaryngol. 2020 Apr 11;:1-5 Authors: Saberi A, Nemati S, Amlashi TT, Tohidi S, Bakhshi F Abstract Background: Epidemiological studies have shown different association between migraine and Meniere's disease (MD). Few studies investigated the frequency of phonophobia in MD.Objectives: This study aimed to determine the frequency...
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Related ArticlesSurgical Outcomes and Efficacy of Isthmusectomy in Single Isthmic Papillary Thyroid Carcinoma: A Preliminary Retrospective Study. J Invest Surg. 2020 Apr 13;:1-6 Authors: Seo HW, Song CM, Ji YB, Jeong JH, Koo HR, Tae K Abstract Background and Objectives: The optimal extent of surgery needed for isthmic papillary thyroid carcinoma (PTC) is not well-defined, although total thyroidectomy is usually recommended. This study aimed to evaluate...
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Related ArticlesThe Impact of Critical Weight Loss and Reactive Feeding Tubes on Cancer-Specific Survival in Head and Neck Cancer. Nutr Cancer. 2020 Apr 11;:1-11 Authors: Vangelov B, Kotevski DP, Smee RI Abstract Critical weight loss (CWL) continues to be a major issue in head and neck cancer (HNC) and many patients require tube feeding. We investigated the use of reactive feeding tubes (RFTs), associated CWL, and the impact on cancer-specific survival...
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Related ArticlesHomeodomain protein DLX4 facilitates nasopharyngeal carcinoma progression via upregulation of YB-1. Genes Cells. 2020 Apr 12;: Authors: Ling Z, Long X, Li J, Feng M Abstract Nasopharyngeal carcinoma (NPC) is a malignant tumor in nasopharynx tissues, and lacks effective treatment strategies. Dysregulation of distal-less homeobox 4 (DLX4) participates in development of tumors. Understanding the regulatory mechanism of DLX4 in NPC progression...
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Related ArticlesAngiolymphoid hyperplasia with eosinophilia of the tongue with a Sézary syndrome history: Evidence for immune mediation of the disease. Australas J Dermatol. 2020 Apr 13;: Authors: Lin SF, Wei YM, Fan Y, Sun CF PMID: 32281101 [PubMed - as supplied by publisher]
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Related ArticlesDeveloping Biodegradable Nanoparticles Loaded with Mometasone Furoate for Potential Nasal Drug Delivery. ACS Omega. 2020 Apr 07;5(13):7432-7439 Authors: Far J, Abdel-Haq M, Gruber M, Abu Ammar A Abstract Intranasal drug administration is considered a routine in the treatment of many nasal conditions including chronic rhinosinusitis (CRS), which is a common disease involving long-term inflammation of the nasal mucosa. Topical nasal...
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Related ArticlesMicrocystic Adnexal Carcinoma of the Face Treated With Definitive Chemoradiation: A Case Report and Review of the Literature. Adv Radiat Oncol. 2020 Mar-Apr;5(2):301-310 Authors: Kim DW, Lee G, Lam MB, Harris EJ, Lam AC, Thomas T, Chau NG, Tishler RB PMID: 32280832 [PubMed]
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Related ArticlesSpatial Radiation Dose Influence on Xerostomia Recovery and Its Comparison to Acute Incidence in Patients With Head and Neck Cancer. Adv Radiat Oncol. 2020 Mar-Apr;5(2):221-230 Authors: Guo Y, Jiang W, Lakshminarayanan P, Han P, Cheng Z, Bowers M, Hui X, Shpitser I, Siddiqui S, Taylor RH, Quon H, McNutt T Abstract Purpose: Radiation-induced xerostomia is one of the most prevalent symptoms during and after head and neck cancer radiation...
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Related ArticlesAvailability of ENT Surgical Procedures and Medication in Low-Income Nation Hospitals: Cause for Concern in Zambia. Biomed Res Int. 2020;2020:1980123 Authors: Lukama L, Kalinda C, Kuhn W, Aldous C Abstract Background: Ear, nose, and throat (ENT) diseases are an oft overlooked global health concern. Despite their high prevalence and associated morbidity and mortality, ENT diseases have remained neglected in health care delivery. In...
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Related ArticlesAn update on angiogenesis targeting in head and neck squamous cell carcinoma. Cancers Head Neck. 2020;5:5 Authors: Micaily I, Johnson J, Argiris A Abstract Angiogenesis is an integral aspect of the growth and proliferation of solid tumors, including head and neck squamous cell carcinoma (HNSCC), and has potential implications in prognosis and treatment of both localized and recurrent/metastatic HNSCC. Therefore, there has been a significant...
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Related ArticlesCancer stem cells and oral cancer: insights into molecular mechanisms and therapeutic approaches. Cancer Cell Int. 2020;20:113 Authors: Baniebrahimi G, Mir F, Khanmohammadi R Abstract Cancer stem cells (CSCs) have been identified as a little population of cancer cells, which have features as the same as the cells normal stem cells. There is enough knowledge of the CSCs responsibility for metastasis, medicine resistance, and cancer...
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Related ArticlesPrognostic value of long non-coding RNA GHET1 in cancers: a systematic review and meta-analysis. Cancer Cell Int. 2020;20:109 Authors: Wang D, Zhang H, Fang X, Zhang X, Liu H Abstract Background: A number of studies have demonstrated the critical role of long non-coding RNA gastric cancer high expressed transcript 1 (GHET1) in many cancers. This meta-analysis provides an evidence-based evaluation of the prognostic role of GHET1 in...
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Related ArticlesDeltonin Ameliorates Cerebral Ischemia/Reperfusion Injury in Correlation with Modulation of Autophagy and Inflammation. Neuropsychiatr Dis Treat. 2020;16:871-879 Authors: Zhang Y, Tian Z, Wan H, Liu W, Kong F, Ma G Abstract Introduction: Deltonin, an active component extracted from Dioscorea zingiberensis C.H. WRIGHT, was widely utilized in traditional Chinese medicines. It has been shown to have anti-cancer functions such as colon...
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Related ArticlesFilter-Membrane-Based Ultrafiltration Coupled with Surface-Enhanced Raman Spectroscopy for Potential Differentiation of Benign and Malignant Thyroid Tumors from Blood Plasma. Int J Nanomedicine. 2020;15:2303-2314 Authors: Liang X, Miao X, Xiao W, Ye Q, Wang S, Lin J, Li C, Huang Z Abstract Objective: The objective of this study is to evaluate the performance and feasibility of surface-enhanced Raman spectroscopy coupled with a filter...
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Related ArticlesVestibular Function Correlates with Radiologic Findings in a Gymnast with 22q11.2DS. Am J Case Rep. 2020 Apr 13;21:e922908 Authors: Moxham LMR, Mallinson AI Abstract BACKGROUND The 22q11.2 deletion syndrome (22q11.2DS) is the most common identified microdeletion in humans. Anomalies of the vestibular system can occur with great frequency and are reported in the radiology literature. Fewer reports exist regarding vestibular function...
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Related ArticlesAgreement on Major Pathological Response in NSCLC Patients Receiving Neoadjuvant Chemotherapy. Clin Lung Cancer. 2020 Mar 04;: Authors: Weissferdt A, Pataer A, Vaporciyan AA, Correa AM, Sepesi B, Moran CA, Wistuba II, Roth JA, Shewale JB, Heymach JV, Kalhor N, Cascone T, Hofstetter WL, Lee JJ, Swisher SG Abstract INTRODUCTION: We have suggested that major pathologic response (MPR) could serve as a surrogate endpoint for survival and...
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Related ArticlesVerrucous hyperplasia and verrucous carcinoma in head and neck: use and benefit of methotrexate. Acta Clin Belg. 2020 Apr 11;:1-5 Authors: De Keukeleire S, De Meulenaere A, Deron P, Huvenne W, Fréderic D, Bouckenooghe O, Ferdinande L, Creytens D, Rottey S Abstract Background and aim: Verrucous hyperplasia (VH) and verrucous carcinoma (VC) of the head and neck are two (pre)malignant entities that are slowly progressive with low tendency...
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Related ArticlesSticky stuff: xerostomia in patients undergoing head and neck radiotherapy-prevalence, prevention, and palliative care. Ann Palliat Med. 2020 Mar 25;: Authors: Snider JW, Paine CC Abstract Xerostomia remains one of the most common and impactful side effects associated with radiotherapy for head and neck malignancies. With improvements in oncologic therapy and an improved prognosis for patients with head and neck squamous cell carcinoma...
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Related ArticlesA Comparison of Olfactory and Sinonasal Outcomes in Endoscopic Pituitary Surgery Performed by a Single Neurosurgeon or a Collaborative Team of Surgeons. Clin Exp Otorhinolaryngol. 2020 Apr 13;: Authors: Noh Y, Choi JE, Lee KE, Kong DS, Nam DH, Jung YG, Kim HY, Chung SK, Hong SD Abstract Objectives: Endoscopic pituitary surgery usually requires a collaboration between neurosurgeons and ENT surgeons to achieve optimal outcomes. However,...
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Related ArticlesEffects of Amniotic Membrane Extract on the Hyperplastic Response of the Middle Ear Mucosa in a Bacterially-Induced Otitis Media Rat Model: A Preliminary Study. Clin Exp Otorhinolaryngol. 2020 Apr 13;: Authors: Park JH, Kim HB, Ko SH, Kim BH, Lim YS, Park SW, Song JJ, Cho CG Abstract Objectives: Human amniotic membrane extract (AME) is known to contain numerous bioactive factors and anti-inflammatory substances. However, the anti-inflammatory...
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Related ArticlesTherapeutic Efficacy of the Modified Epley Maneuver With a Pillow Under the Shoulders. Clin Exp Otorhinolaryngol. 2020 Apr 13;: Authors: Lee HJ, Jeon EJ, Lee DH, Seo JH Abstract Objectives: Canalolithiasis of the posterior semicircular canal (PC) is the most common reason for benign paroxysmal positional vertigo (BPPV). If a patient is diagnosed with PC-BPPV through the Dix-Hallpike test, the modified Epley maneuver (mEpley) is used...
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Related ArticlesPeer-to-Peer Contact Tracing: Development of a Privacy-Preserving Smartphone App. JMIR Mhealth Uhealth. 2020 04 07;8(4):e18936 Authors: Yasaka TM, Lehrich BM, Sahyouni R Abstract BACKGROUND: The novel coronavirus disease 2019 (COVID-19) pandemic is an urgent public health crisis, with epidemiologic models predicting severe consequences, including high death rates, if the virus is permitted to run its course without any intervention or...
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Related ArticlesSurvival differences between definitive radiotherapy and surgery followed by adjuvant radiotherapy in supraglottic and hypopharyngeal carcinoma. Chin Med J (Engl). 2019 Nov 20;132(22):2698-2704 Authors: Zhang M, Gao XS, Qin Y, Sun Y, Ma MW Abstract BACKGROUND: Organ preservation has long been a consideration in the treatment of supraglottic and hypopharyngeal carcinoma to improve the quality of life (QOL). Definitive radiotherapy (DRT)...
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Related ArticlesOverexpression of carboxypeptidase X M14 family member 2 predicts an unfavorable prognosis and promotes proliferation and migration of osteosarcoma. Diagn Pathol. 2019 Oct 24;14(1):118 Authors: Zhao X, Li R, Wang Q, Wu M, Wang Y Abstract BACKGROUND: Carboxypeptidase X, M14 family member 2 (CPXM2), has been associated with several human developmental disorders. However, whether CPXM2 is involved in oncogenesis or tumor progression remains...
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Related ArticlesGreater Tumor Thickness, Ulceration, and Positive Sentinel Lymph Node Are Associated With Worse Prognosis in Patients With Conjunctival Melanoma: Implications for Future AJCC Classifications. Am J Surg Pathol. 2019 12;43(12):1701-1710 Authors: Esmaeli B, Rubin ML, Xu S, Goepfert RP, Curry JL, Prieto VG, Ning J, Tetzlaff MT Abstract Identifying tumor characteristics that correlate with metastasis and survival in patients with conjunctival...
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Related ArticlesMicroRNA miR-31 targets SIRT3 to disrupt mitochondrial activity and increase oxidative stress in oral carcinoma. Cancer Lett. 2019 08 01;456:40-48 Authors: Kao YY, Chou CH, Yeh LY, Chen YF, Chang KW, Liu CJ, Fan Chiang CY, Lin SC Abstract MicroRNA miR-31 is implicated in the neoplastic process of various malignancies including oral squamous cell carcinoma (OSCC). Silent information regulator 3 (Sirtuin3 or SIRT3) is a NAD-dependent deacetylase...
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Related ArticlesChemotherapy acutely impairs neurovascular and hemodynamic responses in women with breast cancer. Am J Physiol Heart Circ Physiol. 2019 07 01;317(7):H1-H12 Authors: Sales ARK, Negrão MV, Testa L, Ferreira-Santos L, Groehs RVR, Carvalho B, Toschi-Dias E, Rocha NG, Laurindo FRM, Debbas V, Rondon MUPB, Mano MS, Hajjar LA, Hoff PMG, Filho RK, Negrão CE Abstract The purpose of the present study was to test the hypothesis that doxorubicin...
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Related ArticlesERR1 and PGC1α associated mitochondrial alterations correlate with pan-cancer disparity in African Americans. J Clin Invest. 2019 03 28;129(6):2351-2356 Authors: Piyarathna DWB, Balasubramanian A, Arnold JM, Lloyd SM, Karanam B, Castro P, Ittmann MM, Putluri N, Navone N, Jones JA, Yu W, Sandulache VC, Sikora AG, Michailidis G, Sreekumar A Abstract BACKGROUND: African American (AA) patients have higher cancer mortality rates and shorter...
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Related ArticlesFeeding tube transparietal thickness - A promising anthropometric parameter for nutritional assessment of endoscopic gastrostomy fed patients. Clin Nutr ESPEN. 2019 02;29:224-230 Authors: Nunes G, Meira T, Patita M, Barata AT, Santos CA, Fonseca J Abstract BACKGROUND & AIMS: Malnutrition is common in patients eligible for percutaneous endoscopic gastrostomy (PEG). Feeding tube transparietal thickness (TT) may contribute to assess...
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Related ArticlesAn Unusual Case of Noisy Breathing in an Infant. J Clin Sleep Med. 2019 01 15;15(1):149-152 Authors: Leon-Astudillo C, Lee GS, Katwa U Abstract ABSTRACT: Laryngomalacia is a common cause of chronic noisy breathing that can present as stridor in infants and neonates. Mild cases of laryngomalacia are usually followed clinically and managed conservatively. However, the evaluation and diagnosis could be challenging in some patients. We...
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Related ArticlesThe role of polysomnography in decannulation of children with brain and spinal cord injuries. Pediatr Pulmonol. 2019 03;54(3):333-341 Authors: Morrow AK, Tunkel DE, Collaco JM, McGrath-Morrow SA, Lam JC, Accardo JA, Rybczynski SV Abstract OBJECTIVE: The objective of this retrospective review was to determine the utility of polysomnography (PSG) in influencing the decision to decannulate pediatric patients with brain and spinal cord...
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Related ArticlesDefining the Minimal Clinically Important Difference for Patients With Vestibular Schwannoma: Are all Quality-of-Life Scores Significant? Neurosurgery. 2019 12 01;85(6):779-785 Authors: Kerezoudis P, Yost KJ, Tombers NM, Celda MP, Carlson ML, Link MJ Abstract BACKGROUND: The diagnosis of vestibular schwannomas (VS) is associated with reduced patient quality of life (QOL). Minimal clinically important difference (MCID) was introduced...
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Related ArticlesPeriodontitis is associated with incident chronic liver disease-A population-based cohort study. Liver Int. 2019 03;39(3):583-591 Authors: Helenius-Hietala J, Suominen AL, Ruokonen H, Knuuttila M, Puukka P, Jula A, Meurman JH, Åberg F Abstract BACKGROUND & AIMS: Chronic liver disease is a major health concern worldwide and the identification of novel modifiable risk factors may benefit subjects at risk. Few studies have analyzed...
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