In order to quantitatively investigate the energy dissipation characteristic during the dynamic tension failure of rock materials, the dynamic Brazilian disc tests on red sandstone were conducted using the split Hopkinson pressure bar (SHPB) setup. The states of the specimens after different incident energies can be divided into three forms (i.e., the unruptured state, the ruptured state, and the broken state), and the failure processes of the specimens were recorded by using a high-speed camera....
14h
In this paper, a new design of a real-time low-cost speed monitoring and closed-loop control of the three-phase induction motor (IM) is proposed. The proposed solution is based on a voltage/frequency (V/F) control approach and a PI antiwindup regulator. It uses the Waijung Blockset which considerably alleviates the heaviness and the difficulty of the microcontroller’s programming task incessantly crucial for the implementation and the management of such complex applications. Indeed, it automatically...
14h
Both numerical simulations and data-driven methods have been applied in dam’s displacement modeling. For monitored displacement data-driven methods, the physical mechanism and structural correlations were rarely discussed. In order to take the spatial and temporal correlations among all monitoring points into account, we took the first step toward integrating the finite element method into a data-driven model. As the data-driven method, we selected the random coefficient model, which can make each...
14h
The conjugate gradient method is very effective in solving large-scale unconstrained optimal problems. In this paper, on the basis of the conjugate parameter of the conjugate descent (CD) method and the second inequality in the strong Wolfe line search, two new conjugate parameters are devised. Using the strong Wolfe line search to obtain the step lengths, two modified conjugate gradient methods are proposed for general unconstrained optimization. Under the standard assumptions, the two presented...
14h
One of the most important threats to today’s civilization is terrorism. Terrorism not only disturbs the law and order situations in a society but also affects the quality of lives of humans and makes them suppressed physically and emotionally and deprives them of enjoying life. The more the civilizations have advanced, the more the people are working towards exploring different mechanisms to protect the mankind from terrorism. Different techniques have been used as counterterrorism to protect the...
14h
Aiming at the problems of early leakage monitoring of urban nonmetallic pipelines and the large positioning error, an inverse transient urban nonmetallic gas pipelines leakage location method based on Markov quantitative judgment was proposed. A Markov flow state transition probability matrix was established based on the flow data under different pressures obtained by experiments to quantitatively determine the pipeline leakage status. On this basis, an inverse transient leakage control equation...
14h
High-modulus asphalt concrete (HMAC) is considered as an effective paving material for addressing the increasing heavy traffic and rutting problems. Therefore, one high-modulus agent was used in this study to prepare high-modulus asphalt binder with different dosages. The objective of this study is to investigate the performance and modification mechanism of high-modulus asphalt. The effects of high-modulus agent on the viscoelastic properties of asphalt with different dosages were quantified via...
14h
In recent years, traditional Chinese medicine has played an important role in the treatment of gastric cancer in China. ZiYinHuaTan (ZYHT) recipe was developed for advanced gastric cancer and had shown its promising value in the clinic. In this study, we explore the effect of ZYHT on gastric cancer in vitro and in vivo. ZYHT can inhibit tumor growth and improve the general condition of mice in subcutaneous transplantation nude mice models of gastric cancer. And ZYHT can also inhibit cell proliferation...
14h
Digital restoration of image with missing data is a basic need for visual communication and industrial applications. In this paper, making full use of priors of low rank and nonlocal self-similarity a gradual reweighted regularization is proposed for matrix completion and image restoration. Sparsity-promoting regularization produces much sparser representation of grouped nonlocal similar blocks of image by solving a nonconvex minimization problem. Moreover, an alternation direction method of multipliers...
14h
Nonalcoholic fatty liver disease, a type of metabolic syndrome, continues to rise globally. Currently, there is no approved drug for its treatment. Improving lifestyle and exercise can alleviate symptoms, but patients’ compliance is poor. More and more studies have shown the potential of Polygoni Multiflori Radix (PMR) in the treatment of NAFLD and metabolic syndrome. Therefore, this paper reviews the pharmacological effects of PMR and its main chemical components (tetrahydroxystilbene glucoside,...
14h
The nonlinear vibrations and responses of a laminated composite cantilever plate under the subsonic air flow are investigated in this paper. The subsonic air flow around the three-dimensional cantilever rectangle laminated composite plate is considered to be decreasing from the wing root to the wing tip. According to the ideal incompressible fluid flow condition and the Kutta–Joukowski lift theorem, the subsonic aerodynamic lift on the three-dimensional finite length flat wing is calculated by using...
14h
As landfill space for the disposal of products of municipal solid waste incineration (MSWI) such as fly ash and slag becomes increasingly scarce, a reduction of disposed material is urgently required. The method of using incineration products in concrete production is explored in this paper through a feasibility study of utilizing fly ash and slag to replace cement and coarse aggregate in appropriate proportions. Results show that C30 concrete optimum replacement rates of fly ash and slag are 30%...
14h
The Tunisian coast is suffering from several active or abandoned polluted sites, suspected to have released high concentrations of various contaminants infiltrating the environment and probably causing groundwater degradation. Within this scope, this study comes to assess and model the Sfax-Agareb aquifer contamination by fluoride released through phosphogypsum leachate percolation. For that, a spatial-temporal monitoring of fluoride contents was achieved for the period between October 2013 and October...
14h
Background. Immunohistochemical assessment of breast cancer and stratification into the basic molecular subtypes afford a much deeper insight into the biology of breast cancer, while presenting with opportunities to exploit personalized, targeted treatment. Traditionally, the oestrogen, progesterone, and epidermal growth factor receptors are assessed. MUC1, a transmembrane mucin, has been demonstrated a potential prognostic and metastatic marker in breast cancer. However, there have been a limited...
14h
Ovarian cancer is the second most common gynaecological malignancy, and microRNAs (miRNAs) play important role in the cancer development. Here, we found that the level of miR-200b/200a/429 was significantly increased in serum and tumor tissues of patients with stage-I ovarian cancer. Consistent with these results, we detected increased expression levels of miR-200b/200a/429 in ovarian cancer cell lines compared with the human nontumorigenic ovarian epithelial cell line T80. The overexpression of...
14h
Objective. To comprehensively evaluate the protective effect of Shenfu injection (SFI) on renal ischaemia/reperfusion injury (IRI) after cardiopulmonary resuscitation (CPR) through neutrophil gelatinase-associated lipocalin (NGAL) and to explore effective monitoring of early renal injuries after CPR. Methods. Thirty healthy minipigs were randomly divided into 3 groups: sham operation (SO) (n = 6), control (n = 12), and SFI (n = 12). The SO group underwent only catheterization, whereas the control...
14h
Background. Alanine aminotransferase (ALT) is referred as liver transaminase and predominantly expressed by hepatocytes. Previous evidences showed that high levels of ALT were reversely associated with short- and long-term outcomes in patients with myocardial infarction. Besides, low lymphocyte has been demonstrated to be significantly correlated with adverse clinical outcomes in coronary artery disease (CAD). However, evidences about the relationship between ALT-to-lymphocyte ratio (ALR) and outcomes...
14h
Polymyxins resistance has emerged worldwide and is threatening the treatment efficacy of multidrug resistant Klebsiella pneumoniae in humans and animals. In this research, we employed whole-genome sequencing (WGS) to investigate the polymyxin B resistance mechanism in selected polymyxin B-susceptible and polymyxin B-resistant K. pneumoniae, isolated from one patient of Huashan Hospital affiliated to Fudan University. The WGS results showed that the two K. pneumoniae all belong to ST11. The average...
14h
Purpose. The goal of this paper is to describe the green conversion of agricultural waste products, such as molasses and corn steep liquor, into large amounts of D(-) lactic acid using a facilitated multipulse fed-batch strategy and affordable pH neutralizer. This is a very low-cost process because there is no need for hydrolysis of the waste products. The fed-batch strategy increases lactic acid productivity by avoiding inhibition caused by a high initial substrate concentration, and the selected...
14h
In this paper, we sought to explore the relationship between apolipoprotein AV (APOAV) overexpression and insulin resistance in hepatocytes. The insulin-resistant HepG2 cell model was constructed, and then, APOAV-overexpressed HepG2 cells (B-M) were induced by infecting with a recombinant adenovirus vector. Microarray data were developed from B-M samples compared with negative controls (A-con), and the microarray data were analyzed by bioinformatic methods. APOAV-overexpression induced 313 upregulated...
14h
Dtsch med WochenschrDOI: 10.1055/a-1152-3469Twenty years ago, an enzyme homologous to the previously known angiotensin-converting enzyme (ACE) was identified, and subsequently named ACE2. In the renin-angiotensin system (RAS), ACE2 has counter-regulatory functions against the classical effector peptide angiotensin II, for example in blood pressure regulation and cardiovascular remodeling. However, ACE2 provides an initially unexpected interesting link between virology and cardiovascular medicine....
2h
Abstract Background and aims Nowadays, advanced age does not represent an absolute contraindication to kidney transplantation (KT). However, aging is frequently associated with multiple comorbidities and lower performance status, making KT candidates less surgically fit. Limited data are available on the impact of KT morbidity on elderly recipients’ outcomes. Methods ...
3h
Around the world, health and social care workers are dying because of occupational exposure to covid-19. Many hundreds have died, including more than 100 in the UK. Are these deaths, and others yet...
4h
Around the world, health and social care workers are dying because of occupational exposure to covid-19. Many hundreds have died, including more than 100 in the UK. Are these deaths, and others yet...
6h
An inquiry into childbirth cases of “serious and potentially serious concern” at Shrewsbury and Telford Hospitals NHS Trust has expanded to 1170 cases, putting it on course to be one of the biggest...
11h
The recent publication of an industry sponsored, open, non-randomised study of remdesivir in a heterogeneous patient population has added to the confusion surrounding the drug treatment of...
11h
The European Medicines Agency’s pharmacovigilance risk assessment committee (PRAC) has recommended updating the product information for drugs containing ibuprofen and ketoprofen to warn that they can...
11h
“Deep breath in ... and out. Again, deep breath in … and out.”We tune in to patients’ breath sounds, seeking confirmation of a diagnosis—one more supporting piece of evidence to reassure anxious...
11h
Like many people around the world just now, those living in the São Paulo neighbourhood of Paraisópolis are terrified of covid-19. But, with a national president in denial of the pandemic and...
11h
New figures showing a sharp rise in the number of deaths in care homes in England and Wales are “deeply alarming” and demonstrate the need for better surveillance and protection for residents against...
11h
An inquiry into childbirth cases of “serious and potentially serious concern” at Shrewsbury and Telford Hospitals NHS Trust has expanded to 1170 cases, putting it on course to be one of the biggest...
12h
The recent publication of an industry sponsored, open, non-randomised study of remdesivir in a heterogeneous patient population has added to the confusion surrounding the drug treatment of...
13h
The European Medicines Agency’s pharmacovigilance risk assessment committee (PRAC) has recommended updating the product information for drugs containing ibuprofen and ketoprofen to warn that they can...
13h
“Deep breath in ... and out. Again, deep breath in … and out.”We tune in to patients’ breath sounds, seeking confirmation of a diagnosis—one more supporting piece of evidence to reassure anxious...
15h
Like many people around the world just now, those living in the São Paulo neighbourhood of Paraisópolis are terrified of covid-19. But, with a national president in denial of the pandemic and...
15h
New figures showing a sharp rise in the number of deaths in care homes in England and Wales are “deeply alarming” and demonstrate the need for better surveillance and protection for residents against...
16h
The rapid scale-up of malaria prevention and treatment over the past two decades has led to significant reductions in its related morbidity and mortality worldwide. In sub-Saharan Africa, where over...
18h
Older age and a range of underlying medical conditions mean a higher risk of serious illness, admission, and death from covid-19 than in younger or fitter groups. Over 70s have been advised to avoid...
18h
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου