Laser interstitial thermal therapy (LITT) is a stereotactic-guided technique, which is increasingly being performed for brain lesions.

National Trends and Factors Predicting Outcomes Following Laser Interstitial thermal therapy (LITT) for Brain Lesions: A Nationwide Inpatient Sample Analysis.:

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National Trends and Factors Predicting Outcomes Following Laser Interstitial thermal therapy (LITT) for Brain Lesions: A Nationwide Inpatient Sample Analysis.

World Neurosurg. 2020 Apr 03;:

Authors: Sharma M, Ugiliweneza B, Wang D, Boakye M, Andaluz N, Neimat J, Mohammadi A, Barnett GH, Williams BJ

Abstract

INTRODUCTION: Laser interstitial thermal therapy (LITT) is a stereotactic-guided technique, which is increasingly being performed for brain lesions. The aim of our study was to report the national trends and factors predicting the clinical outcomes following LITT using the Nationwide Inpatient Sample (NIS).

METHODS: We extracted data from 2011-2016 using ICD-9/10 codes. Patients with a primary procedure of LITT were included. Patient demographics, complications, length of hospital stay (LOS), discharge disposition and index-hospitalization charges were analyzed.

RESULTS: A cohort of 1768 patients was identified from the database. Mean LOS was 3.2 days, 82% of patients were discharged to home and in-hospitalization cost was $124,225. Complications and mortality were noted in 12.9% and 2.5% of patients following LITT, respectively. Non-Caucasian patients (ER 4.26), those with other insurance (compared to commercial, ER: 5.35), 3 and 4+ comorbidity indexes, patients with higher quartile median household income (2nd, 3rd and 4th quartile compared to first quartile) and those who underwent non-elective procedures were likely to have higher complications and less likely to be discharged home. Patients with 4+ comorbidity indexes were likely to have longer LOS (ER 1.39), higher complications (ER: 7.95), less likely to be discharged home (ER: 0.17) and higher in-hospitalization cost (ER: 1.21).

CONCLUSION: LITT is increasingly being performed with low complication rates. Non-Caucasian race, higher comorbidity index, non-commercial insurance and non-elective procedures were predictors of higher complications and less likely to be discharged home. In-hospitalization charges were higher in patients with higher comorbidity index and those with non-commercial insurance.

PMID: 32251808 [PubMed - as supplied by publisher]