Τετάρτη 1 Απριλίου 2020


Mendelian Randomization of Circulating Polyunsaturated Fatty Acids and Colorectal Cancer Risk
Background:Results from epidemiologic studies examining polyunsaturated fatty acids (PUFA) and colorectal cancer risk are inconsistent. Mendelian randomization may strengthen causal inference from observational studies. Given their shared metabolic pathway, examining the combined effects of aspirin/NSAID use with PUFAs could help elucidate an association between PUFAs and colorectal cancer risk. Methods:Information was leveraged from genome-wide association studies (GWAS) regarding PUFA-associated...
Cancer Epidemiology Biomarkers & Prevention current issue
21h
Self-efficacy and Physical Activity in Overweight and Obese Adults Participating in a Worksite Weight Loss Intervention: Multistate Modeling of Wearable Device Data
Background:Physical activity is associated with a reduced risk of numerous types of cancer and plays an important role in maintaining a healthy weight. Wearable physical activity trackers may supplement behavioral intervention and enable researchers to study how determinants like self-efficacy predict physical activity patterns over time. Methods:We used multistate models to evaluate how self-efficacy predicted physical activity states among overweight and obese individuals participating in a 26-week...
Cancer Epidemiology Biomarkers & Prevention current issue
21h
The Impact of Exclusive Use of Very Low Nicotine Cigarettes on Compensatory Smoking: An Inpatient Crossover Clinical Trial
Background:The FDA is considering a mandated reduction in the nicotine content of cigarettes. Clinical trials have been limited by non-study cigarette use (noncompliance), which could mask compensation. The goal of this study was to assess whether compensation occurs when smokers provided with very low nicotine cigarettes cannot access normal nicotine cigarettes. Methods:In a within-subjects, crossover design, current smokers (n = 16) were confined to a hotel for two 4-night hotel stays during...
Cancer Epidemiology Biomarkers & Prevention current issue
21h
The estimated prevalence of exposure to carcinogens, asthmagens, and ototoxic agents among healthcare workers in Australia
Abstract Background Healthcare workers are occupationally exposed to various hazardous chemicals and agents that can potentially result in long‐term adverse health effects. These exposures have not been comprehensively examined at a population level. The aim of this study was to examine occupational exposures to a wide range of asthmagens, carcinogens, and ototoxic agents among healthcare workers in Australia. Methods Data were collected as part of the Australian Work Exposures Studies,...
American Journal of Industrial Medicine
22h
RCC2 contributes to tumor invasion and chemoresistance to cisplatin in hepatocellular carcinoma
Abstract Tumor metastasis and chemoresistance are the main causes of treatment failure and high mortality in hepatocellular carcinoma (HCC). Therefore, it is critical to clarify the biological action and potential mechanisms in HCC cells to develop novel therapeutics. The regulator of chromosome condensation 2 (RCC2), a component of the chromosomal passenger complex, was shown to have important roles in tumor development and radio-chemotherapy resistance. However, its role in the aggressive...
Latest Results for Human Cell
23h
Author's reply to the Letter to the Editor “Prospective evaluation of oral corticosteroid as a predictor of postoperative olfactory recovery after functional endoscopic surgery for nasal polyposis”
Latest Results for European Archives of Oto-Rhino-Laryngology
23h
Predicting the treatment outcome of nivolumab in recurrent or metastatic head and neck squamous cell carcinoma: prognostic value of combined performance status and modified Glasgow prognostic score
Abstract Purpose The importance of nivolumab for recurrent or metastatic (R/M) head and neck squamous cell carcinoma (HNSCC) is rapidly increasing. However, prognostic factors have not been determined for predicting treatment outcome. We aimed to investigate the prognostic factors in R/M HNSCC patients treated with nivolumab. Methods This retrospective study...
Latest Results for European Archives of Oto-Rhino-Laryngology
23h

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