Related ArticlesAssociation of chemosensory dysfunction and Covid-19 in patients presenting with influenza-like symptoms. Int Forum Allergy Rhinol. 2020 Apr 12;: Authors: Yan CH, Faraji F, Prajapati DP, Boone CE, DeConde AS Abstract BACKGROUND: Rapid spread of the SARS-CoV-2 virus and concern for viral transmission by ambulatory patients with minimal to no symptoms underline the importance of identifying early or subclinical symptoms of Covid-19...
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Related ArticlesPreoperative evaluation of microvascular invasion with circulating tumor DNA in operable hepatocellular carcinoma. Liver Int. 2020 Apr 12;: Authors: Wang D, Xu Y, Goldstein JB, Ye K, Hu X, Xiao L, Li L, Chang L, Guan Y, Long G, He Q, Yi X, Zhang J, Wang Z, Xia X, Zhou L Abstract BACKGROUND & AIMS: Microvascular invasion (MVI) is a critical prognostic factor for operable hepatocellular carcinoma (HCC). This study aimed to explore...
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Related ArticlesThe Receptive Field for Visceral Pain Referred Orofacially by the Vagus Nerves. Clin Anat. 2020 Apr 12;: Authors: Myers DE Abstract The nociceptive receptive field of the vagus nerves in animals includes virtually the entire thoracic, abdominal and laryngopharyngeal regions. However, the role of the vagus nerves in the transmission of visceral pain in humans, with the exception of pain from coronary artery diseases, is believed to...
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Related ArticlesEpstein-Barr virus and human papillomavirus serum antibodies define the viral status of nasopharyngeal carcinoma in a low endemic country. Int J Cancer. 2020 Apr 12;: Authors: Simon J, Schroeder L, Ingarfield K, Diehl S, Werner J, Brenner N, Liu Z, Pawlita M, Pring M, Butt J, Ness A, Waterboer T Abstract Epstein-Barr virus (EBV) causes nasopharyngeal carcinoma (NPC) in endemic regions, where almost every tumor is EBV-positive. In...
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Related ArticlesIdentification of Rare and Common HPV Genotypes in Sinonasal Papillomas. Head Neck Pathol. 2020 Apr 11;: Authors: Vor der Holte AP, Fangk I, Glombitza S, Wilkens L, Welkoborsky HJ Abstract Sinonasal papillomas are rare, usually benign tumors arising from the Schneiderian membrane. Human papillomaviruses (HPV) can infect differentiating skin and mucosal cells and can induce uncontrolled growth patterns. Their effect on development...
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Related ArticlesMandibular dental implant placement immediately after teeth removal in head and neck cancer patients. Support Care Cancer. 2020 Apr 11;: Authors: Alberga JM, Korfage A, Bonnema I, Witjes MJH, Vissink A, Raghoebar GM Abstract BACKGROUND: Little is known about immediate implant placement in head and neck cancer patients. We studied implant survival and functional outcomes of overdentures fabricated on implants placed immediately after...
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Related ArticlesChronic invasive fungal rhinosinusitis vs sinonasal squamous cell carcinoma: the differentiating value of MRI. Eur Radiol. 2020 Apr 11;: Authors: Li Z, Wang X, Jiang H, Qu X, Wang C, Chen X, Chong VF, Zhang L, Xian J Abstract OBJECTIVES: To investigate MRI features in discriminating chronic invasive fungal rhinosinusitis (CIFRS) from sinonasal squamous cell carcinomas (SNSCC). METHODS: MRI findings of 33 patients with CIFRS...
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Related ArticlesA comparison of endoscopic transtympanic myringoplasty and endoscopic type I tympanoplasty for repairing medium- to large-sized tympanic membrane perforation: a randomized clinical trial. Eur Arch Otorhinolaryngol. 2020 Apr 11;: Authors: Atchariyasathian V, Suwannajak R, Plodpai Y, Pitathawatchai P Abstract INTRODUCTION: Endoscopic type I tympanoplasty (ETT) is currently accepted as an effective, minimally traumatic procedure for...
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Related ArticlesSpontaneous neck hematoma secondary to parathyroid adenoma: a case series. Eur Arch Otorhinolaryngol. 2020 Apr 11;: Authors: Tessler I, Adi M, Diamant J, Lahav Y, Halperin D, Cohen O Abstract PURPOSE: Spontaneous neck hematoma is a rare yet potentially fatal complication of primary hyperparathyroidism (PHPT). Here we aim to describe novel presentations of neck hematomas secondary to PHPT, discussing tools and signs that facilitate...
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Related ArticlesIntratemporal facial nerve schwannomas: multicenter experience of 80 cases. Eur Arch Otorhinolaryngol. 2020 Apr 11;: Authors: Loos E, Verhaert N, Darrouzet V, Godey B, Linder T, Vincent C, Lavieille JP, Schmerber S, Lescanne E, Trabalzini F, De Foer B, Van Havenbergh T, Somers T Abstract PURPOSE: To provide more data on the clinical presentation and natural evolution of facial nerve schwannomas and to provide guidance for therapeutic...
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Related ArticlesInhibition of cyclin-dependent kinases by AT7519 enhances nasopharyngeal carcinoma cell response to chemotherapy. Cancer Chemother Pharmacol. 2020 Apr 11;: Authors: Wei X, Nian J, Zheng J, He Y, Zeng M Abstract BACKGROUND: The poor outcomes in nasopharyngeal carcinoma (NPC) necessitate new treatments. AT7519 is a potent inhibitor of several cyclin-dependent kinases (CDKs) and is currently in the early phase of clinical development...
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Related ArticlesDiffusion kurtosis imaging in head and neck cancer: A correlation study with dynamic contrast enhanced MRI. Phys Med. 2020 Apr 09;73:22-28 Authors: Minosse S, Marzi S, Piludu F, Boellis A, Terrenato I, Pellini R, Covello R, Vidiri A Abstract PURPOSE: To investigate the biophysical meaning of Diffusion Kurtosis Imaging (DKI) parameters via correlations with the perfusion parameters obtained from a long Dynamic Contrast Enhanced MRI...
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Related ArticlesAssessing non-aggressiveness of untreated, local and regional, papillary thyroid cancer. Oral Oncol. 2020 Apr 09;105:104674 Authors: van Gerwen M, Alpert N, Sinclair C, Kale M, Genden E, Taioli E Abstract OBJECTIVES: With a steadily increasing thyroid cancer incidence, information regarding cancer aggressiveness is essential to determine which patients may be suitable for active surveillance. This study assessed the extent of non-aggressiveness...
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Related ArticlesThe role of tumour morphology in assigning HPV status in oropharyngeal squamous cell carcinoma. Oral Oncol. 2020 Apr 09;105:104670 Authors: Molony P, Werner R, Martin C, Callanan D, Nauta I, Heidemann D, Sheahan P, Heffron C, Feeley L Abstract OBJECTIVES: There is no consensus on the optimal approach to human papilloma virus (HPV) testing in oropharyngeal squamous cell carcinoma (OPSCC). Our objective was to classify OPSCC as HPV...
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Related ArticlesAbnormal cochleovestibular anatomy and imaging: Lack of consistency across quality of images, sequences obtained, and official reports. Int J Pediatr Otorhinolaryngol. 2020 Apr 05;134:110021 Authors: Gillard DM, Chuang NA, Go JL, Kari E Abstract OBJECTIVES: There are significant variations across centers on how to acquire and interpret imaging of children with congenital sensorineural hearing loss and cochleovestibular abnormalities....
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Related ArticlesThe lingual sulcus release technique for excision of tongue cancer with trismus. Int J Oral Maxillofac Surg. 2020 Apr 08;: Authors: Rao V, Sinha P, Subash A, Thakur S Abstract Operable oral tongue cancers are managed best with surgery followed by adjuvant therapy as and when indicated. The only factor that affects the prognosis, and is under the control of a surgeon, is the tumour margin. Often in cases with trismus, which is prevalent...
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Related ArticlesTophaceous pseudogout of the temporomandibular joint with erosion into the middle cranial fossa. Int J Oral Maxillofac Surg. 2020 Apr 08;: Authors: Houghton D, Munir N, Triantafyllou A, Begley A Abstract This report presents a case of extensive tophaceous pseudogout involving the temporomandibular joint (TMJ), causing erosion into the middle cranial fossa. Pseudogout is a benign metabolic arthropathy caused by calcium pyrophosphate...
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Related ArticlesThe Effects of Contextual Priming and Alaryngeal Speech Mode on Auditory-Perceptual Ratings of Listener Comfort. J Voice. 2020 Apr 08;: Authors: Failla S, Al-Zanoon N, Smith N, Doyle PC Abstract BACKGROUND: The effectiveness of postlaryngectomy communication methods (esophageal, tracheoesophageal, and electrolaryngeal speech) has been primarily evaluated using functional outcomes. This evaluation neglects the importance of listeners...
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Related ArticlesDifferential diagnosis and management of adult-onset laryngomalacia. Am J Otolaryngol. 2020 Apr 02;:102469 Authors: Ferri GM, Prakash Y, Levi JR, Tracy LF Abstract OBJECTIVE: Adult-onset laryngomalacia is a rare clinical entity that has been infrequently reported. This study aims to evaluate the clinical presentation, diagnosis, and management of adult-onset laryngomalacia through literature review and report of a case. ...
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Related ArticlesManagement of Sinusitis in the Cystic Fibrosis Patient. Immunol Allergy Clin North Am. 2020 May;40(2):371-383 Authors: Okafor S, Kelly KM, Halderman AA Abstract Chronic rhinosinusitis (CRS) is present in up to 100% of patients with cystic fibrosis (CF). CF-associated CRS is particularly recalcitrant, and sinus disease can have important implications in the health of the lower airways and overall quality of life in these patients....
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Related ArticlesCurrent Concepts in the Management of Allergic Fungal Rhinosinusitis. Immunol Allergy Clin North Am. 2020 May;40(2):345-359 Authors: Tyler MA, Luong AU Abstract Allergic fungal rhinosinusitis (AFRS) represents a subtype of chronic rhinosinusitis with nasal polyposis that exhibits a unique, often striking clinical presentation. Since its initial description more than a quarter century ago, a more sophisticated understanding of the...
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Related ArticlesTopical Irrigations for Chronic Rhinosinusitis. Immunol Allergy Clin North Am. 2020 May;40(2):317-328 Authors: Lee VS Abstract As the understanding of the primary cause of chronic rhinosinusitis has shifted away from infection toward inflammation, topical corticosteroid sprays and saline irrigations have become mainstays of treatment. Topical corticosteroid irrigations are recommended particularly in the postoperative setting, but...
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Related ArticlesThe Role of Macrolides and Doxycycline in Chronic Rhinosinusitis. Immunol Allergy Clin North Am. 2020 May;40(2):303-315 Authors: Lees KA, Orlandi RR, Oakley G, Alt JA Abstract Antibiotic therapy has become an important adjunct in the management of recalcitrant chronic rhinosinusitis (CRS) because of some antibiotics' immunomodulatory properties even at subtherapeutic antimicrobial levels. Macrolide antibiotics, such as clarithromycin...
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Related ArticlesThe Role of Biologics in the Treatment of Nasal Polyps. Immunol Allergy Clin North Am. 2020 May;40(2):295-302 Authors: Franzese CB Abstract Chronic rhinosinusitis with nasal polyps (CRSwNP) is a heteromorphic disease with both medical and surgical aspects to its treatment. CRSwNP is a chronic inflammatory condition with exacerbations that can be controlled through surgical and/or medical interventions, including biological agents....
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Related ArticlesPersonalized Medicine in Chronic Rhinosinusitis: Phenotypes, Endotypes, and Biomarkers. Immunol Allergy Clin North Am. 2020 May;40(2):281-293 Authors: Bauer AM, Turner JH Abstract Chronic rhinosinusitis (CRS) is a heterogeneous disease process with a complex underlying cause. Improved understanding of CRS pathophysiology has facilitated new approaches to management of the patient with CRS that rely on targeting patient-specific characteristics...
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Related ArticlesMeasuring Success in the Treatment of Patients with Chronic Rhinosinusitis. Immunol Allergy Clin North Am. 2020 May;40(2):265-279 Authors: Chowdhury N, Smith TL, Beswick DM Abstract Chronic rhinosinusitis (CRS) has a substantial impact on patients' quality of life (QOL). Among the many metrics available for measuring treatment success in CRS, patient-reported outcome measures that quantify changes in QOL are the most widely used methods....
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Related ArticlesThe Microbiome and Chronic Rhinosinusitis. Immunol Allergy Clin North Am. 2020 May;40(2):251-263 Authors: Cho DY, Hunter RC, Ramakrishnan VR Abstract Chronic rhinosinusitis (CRS) is persistent inflammation and/or infection of the nasal cavity and paranasal sinuses. Recent advancements in culture-independent molecular techniques have enhanced understanding of interactions between sinus microbiota and upper airway microenvironment....
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Related ArticlesPrimary Immunodeficiency and Rhinosinusitis. Immunol Allergy Clin North Am. 2020 May;40(2):233-249 Authors: Huwyler C, Lin SY, Liang J Abstract Refractory rhinosinusitis can be related to comorbid medical conditions, including primary immunodeficiency. Given the prevalence of immunodeficiency, clinicians should have a low threshold to consider these diagnoses. This article reviews primary immunodeficiencies contributing to chronic...
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Related ArticlesOlfactory Dysfunction and Chronic Rhinosinusitis. Immunol Allergy Clin North Am. 2020 May;40(2):223-232 Authors: Ahmed OG, Rowan NR Abstract Olfactory dysfunction (OD) is one of the cardinal symptoms of chronic rhinosinusitis (CRS), and its prevalence ranges from 60% to 80% in patients with CRS. It is much more common in CRS with nasal polyposis patients compared to CRS without nasal polyposis. Decreased olfactory function is associated...
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Related ArticlesWhat is the Role of Air Pollution in Chronic Rhinosinusitis? Immunol Allergy Clin North Am. 2020 May;40(2):215-222 Authors: Schwarzbach HL, Mady LJ, Lee SE Abstract Chronic rhinosinusitis (CRS) is a heterogeneous inflammatory disorder, and several environmental factors may be contributing to disease pathophysiology, including air pollutants. Tobacco smoke and occupational exposures also have been associated with CRS, and environmental...
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