Τετάρτη 1 Απριλίου 2020


The possibility of using Scots pine needles as biomonitor in determination of heavy metal accumulation
Abstract One of the biggest problems of modern world is the air pollution which causes the death of millions of people every year. The heavy metals included in the component of air pollution occupy an important position in human health since they could remain intact in nature for a long time and build bioaccumulation, and also some of them are toxic or carcinogenic even at some low concentrations. Even the heavy metals functioning as micronutrient element could create toxic effect...
Latest Results
4m
Chemical characterization of mountain forest soils: impact of long-term atmospheric deposition loadings (Czech–Polish–German border region)
Abstract The composition of lipids in soil offers clues to soil degradation processes due their persistency and selectivity in soil, and close relation to long-term processes in the ecosystem, thanks to their role in cell membranes of organisms. Organic solvent-extractable compounds were recovered from soils collected at two sites differing in the degree of forest damage. Gas chromatography/mass spectroscopy and Fourier transform infrared spectroscopy were applied in order to characterize...
Latest Results
2h
Grey water footprint evaluation and driving force analysis of eight economic regions in China
Abstract The grey water footprint (GWF) can be used to connect wastewater quality and quantity, making it a powerful tool for policy makers and those responsible for managing wastewater systems. As a supplementary to existing GWF research, this study explores the GWF evolution of eight economic regions in China by taking into consideration the GWF of livestock feeding. In addition, we use the logarithmic mean division index method to study the background driving forces of GWF in...
Latest Results
2h
Antioxidant defence barrier of great tit Parus major nestlings in response to trace elements
Abstract Metals can have direct and indirect effects on the generation of reactive oxygen species in wild birds. The aim of this work has been to examine the effect of exposure to trace metals (copper Cu, iron Fe, cobalt Co, manganese Mn) on oxidative stress biomarkers such as lipoperoxidation TBARS and level of superoxide dismutase SOD, catalase CAT, and reduced glutathione GSH in the livers and kidneys of great tit Parus major nestlings (n = 165, 63 broods) living in polluted...
Latest Results
3h
Spatial distribution of endemic fluorosis caused by drinking water in a high-fluorine area in Ningxia, China
Abstract Endemic fluorosis is widespread in China, especially in the arid and semi-arid areas of northwest China, where endemic fluorosis caused by consumption of drinking water high in fluorine content is very common. We analyzed data on endemic fluorosis collected in Ningxia, a typical high-fluorine area in the north of China. Fluorosis cases were identified in 539 villages in 1981, in 4449 villages in 2010, and in 3269 villages in 2017. These were located in 19 administrative...
Latest Results
3h
A time series of land cover maps of South Asia from 2001 to 2015 generated using AVHRR GIMMS NDVI3g data
Abstract In South Asia, key differences in annual land use and land cover (LULC) take place due to climate change, global warming, human activity, biodiversity, and hydrology. So, it is very important to get accurate land cover information for this region. An annual LULC map that covers a comprehensive period is a major dataset for climatologically study. While yearly worldwide maps of LULC are produced from Moderate Resolution Imaging Spectroradiometer (MODIS) dataset, in 2001,...
Latest Results
3h
Environmental assessment of physical-chemical features of Lake Nasser, Egypt
Abstract Lake Nasser is one of the largest man-made lakes on earth. It has a vital importance to Egypt for several decades because of the safe water supply of the country. Therefore, the water quality of the Lake Nasser must be profoundly investigated, and physico-chemical parameter changes of the water of the Lake Nasser should be continuously monitored and assessed. This work describes the present state of the physico-chemical (nitrate-nitrogen, nitrite-nitrogen, orthophosphate,...
Latest Results
3h
Metal concentrations in fish from nine lakes of Anhui Province and the health risk assessment
Abstract In the present study, to comprehensively investigate the metal contamination in the fish of Anhui Province, four fish species, Ctenopharyngodon idella, Cyprinus carpio, Hypophthalmichthys molitrix, and Hypophthalmichthys nobilis, were collected from nine lakes, and the levels of Zn, Pb, Cr, Cu, Ni, As, Hg, and Cd in the fish muscle were determined. The results showed that the highest concentrations of Zn (7.791 mg/kg), Pb (0.522 mg/kg), Cr (0.030 mg/kg), and Cu (0.767 mg/kg)...
Latest Results
3h
Histopathologic, apoptotic and autophagic, effects of prenatal bisphenol A and/or di(2-ethylhexyl) phthalate exposure on prepubertal rat testis
Abstract Bisphenol A (BPA) and di(2-ethylhexyl) phthalate (DEHP) are endocrine-disrupting chemicals (EDCs) used in a wide variety of industrial products as plasticizers. Exposure to EDCs, particularly in mixtures, in prenatal and early postnatal periods may lead to unwanted effects and can cause both developmental and reproductive problems. In this study, we aimed to determine the individual and combined effects of prenatal and lactational exposure to BPA and/or DEHP on testicular...
Latest Results
4h
Effects of soil heavy metal pollution on microbial activities and community diversity in different land use types in mining areas
Abstract Microbial activities and community structures play crucial roles in the soil environment and can be served as effective indicators to assess the ecological influence of heavy metal pollution in soil. This article selected soil samples from five land use types (mining area, mineral processing area, heap mining area, tailing area, and vegetable area) in the Shizishan mining area in Tongling, Anhui Province, China. The physicochemical properties, pollution characteristics,...
Latest Results
4h
Thiosemicarbazone nano-formulation for the control of Aspergillus flavus
Abstract Nanoparticles are widely studied for applications in medical science. In recent years, they have been developed for agronomical purposes to target microbial pest such as bacteria, fungi, and viruses. Nanoparticles are also proposed to limit the use of pesticides, whose abuse is causing environmental impact and human health concerns. In this study, nanoparticles were obtained by using poly-(ε-caprolactone), a polyester chosen for its biocompatibility and biodegradability...
Latest Results
4h
Influence of slope aspect on the macro- and micronutrients in Artemisia sacrorum on the Loess Plateau in China
Abstract Slope aspect is an important topographic factor for a micro-ecosystem environment that may affect macro- and micronutrients in plants and soil. The south-, northwest-, and north-facing slopes were selected to investigate the influence of slope aspect on the concentrations, storage, and allocation of macro- and micronutrients in Artemisia sacrorum on the Loess Plateau in China. The concentrations of available manganese (Mn) in both rhizosphere and non-rhizosphere soils...
Latest Results
8h
Layered double hydroxides and LDH-derived materials in chosen environmental applications: a review
Abstract With increasing global warming awareness, layered double hydroxides (LDHs), hydrotalcites, and their related materials are key components to reduce the environmental impact of human activities. Such materials can be synthesized quickly with high efficiency by using different synthesis processes. Moreover, their properties’ tunability is appreciated in various industrial processes. Regarding physical and structural properties, such materials can be applied in environmental...
Latest Results
10h
Fluorescent conjugated microporous polymers containing pyrazine moieties for adsorbing and fluorescent sensing of iodine
Abstract Two kinds of fluorescent conjugated microporous polymers containing pyrazine moieties were prepared by the polymerization reaction of 2,5-di-triphenylamine-yl-pyrazine (DTPAPz) and N,N,N′,N′-tetrapheny-2,5-(diazyl) pyrazine (TDPz) with 2,4,6-trichloro-1,3,5-triazine (TCT) through Friedel–Crafts reaction using the methanesulfonic acid as a catalysts. Both CMPs have high thermal stability and decomposition temperature reaches above 596 and 248 °C under nitrogen atmosphere,...
Latest Results
11h
Thermodynamic study of the acid-induced decontamination of waste green sand generated in a brass foundry
Abstract Waste foundry sand (WFS) from the brass and bronze casting and molding process include various potentially toxic elements (PTEs), such as copper, zinc, tin, and lead. Hence, the utilization of WFS in construction and geotechnical applications evokes environmental concerns due to the rain-induced leaching of PTEs into the groundwater system. The present study investigated the extractive decontamination of WFS using mineral acids, e.g., HCl, H2SO4, or HNO3. Favorable extraction...
Latest Results
11h
Kinetic modeling of molybdenum sorption and transport in soils
Abstract In this investigation, batch and column experiments were conducted to investigate the molybdenum (Mo) sorption and transport processes on a neutral-pH soil (Webster loam) and an acidic soil (Mahan sand) in Ca2+ and K+ background solutions. Batch results showed that the adsorption of Mo was strongly non-linear in both soils and amount of Mo sorbed in the acidic soil was larger than the neutral soil. The Freundlich distribution coefficients (Kf) and Langmuir sorption maxima...
Latest Results
11h
Metals, arsenic, pesticides, and microcystins in tilapia ( Oreochromis niloticus ) from aquaculture parks in Brazil
Abstract The production of Nile tilapia (Oreochromis niloticus) in Brazil exhibits the highest growth rate in the world and represents approximately 45% of the total fish production. The objective of the present study was to assess the risk for human health due the consumption of tilapia farmed in net cages in eight aquaculture parks in Brazil. The concentrations of pesticides (40 compounds), metals (Mn, Ni, Zn, Cd, Pb, and Sn), arsenic, and cyanotoxins (microcystins) were evaluated...
Latest Results
15h
Adulticidal activities of Cymbopogon citratus (Stapf.) and Eucalyptus globulus (Labill.) essential oils and of their synergistic combinations against Aedes aegypti (L.), Aedes albopictus (Skuse), and Musca domestica (L.)
Abstract The knockdown and adulticidal activities of individual Cymbopogon citratus and Eucalyptus globulus essential oils (EOs) and their combinations were evaluated against three medical insect pests (Aedes aegypti, Aedes albopictus, and Musca domestica) using a WHO susceptibility test. The knockdown and adulticidal activities against the three medical insect pests of combinations of C. citratus and E. globulus EOs were higher than those of individual EOs alone. Combinations...
Latest Results
22h
Toxicology data of graphene-family nanomaterials: an update
Abstract Due to its unique physical structure and chemical properties, graphene family nanomaterials (GFNs) and derived commodities have been widely used in commercial products, particularly biomedical applications, which has significantly increased the risk of human exposure. There exists significant evidence that GFNs are accumulated in a number of tissues and organs through different exposure pathways, and further cause toxicity manifested as lesions or functional impairment....
Latest Results for Archives of Toxicology
12m
Comparison of the toxicokinetics of the convulsants picrotoxinin and tetramethylenedisulfotetramine (TETS) in mice
Abstract Acute intoxication with picrotoxin or the rodenticide tetramethylenedisulfotetramine (TETS) can cause seizures that rapidly progress to status epilepticus and death. Both compounds inhibit γ-aminobutyric acid type-A (GABAA) receptors with similar potency. However, TETS is approximately 100 × more lethal than picrotoxin. Here, we directly compared the toxicokinetics of the two compounds following intraperitoneal administration in mice. Using LC/MS analysis we found that...
Latest Results for Archives of Toxicology
12h
High complexity of toxic reactions: parallels between products of oxidative stress and advanced glycation end products
Latest Results for Archives of Toxicology
16h
Quantification of the affinities of CRISPR-Cas9 nucleases for cognate protospacer adjacent motif (PAM) sequences [Molecular Biophysics]
The CRISPR/Cas9 nucleases have been widely applied for genome editing in various organisms. Cas9 nucleases complexed with a guide RNA (Cas9/gRNA) find their targets by scanning and interrogating the genomic DNA for sequences complementary to the gRNA. Recognition of the DNA target sequence requires a short protospacer adjacent motif (PAM) located outside this sequence. Given that the efficiency of target location may depend on the strength of interactions that promote target recognition, here we...
JBC Papers in Press
42m
An arrestin-1 surface opposite of its interface with photo-activated rhodopsin engages with enolase-1 [Protein Structure and Folding]
Arrestin-1 is the arrestin-family member responsible for inactivation of the G protein-coupled receptor rhodopsin in photoreceptors. Arrestin-1 is also well known to interact with additional protein partners and to affect other signaling cascades beyond phototransduction. In this study, we investigated one of these alternative arrestin-1 binding partners, the glycolysis enzyme enolase-1, to map the molecular contact sites between these two proteins and investigate how the binding of arrestin-1 affects...
JBC Papers in Press
2h
Non-photopic and photopic visual cycles differentially regulate immediate, early and late-phases of cone photoreceptor-mediated vision [Molecular Bases of Disease]
Cone photoreceptors in the retina enable vision over a wide range of light intensities. However, the processes enabling cone vision in bright light (i.e. photopic vision) are not adequately understood. Chromophore regeneration of cone photopigments may require the retinal pigment epithelium (RPE) and/or retinal Müller glia. In the RPE, isomerization of all-trans-retinyl esters (atRE) to 11-cis-retinol (11cROL) is mediated by the retinoid isomerohydrolase Rpe65. A putative alternative retinoid isomerase,...
JBC Papers in Press
2h
Sedative and Hypnotic Effects and Transcriptome Analysis of Polygala tenuifolia in Aged Insomnia Rats
Abstract Objective To study the sedative and hypnotic effects and underlying mechanisms of Polygala tenuifolia (PT) on treating aged insomnia rats. Methods Sixty Sprague-Dawley male rats were divided into 6 groups by a random number table, including control group, model group, diazepam group (0.92 mg/kg), as well as PT low-, medium- and high-dose groups...
Latest Results for Chinese Journal of Integrative Medicine
47m
Heat-Clearing Chinese Medicines in Lipopolysaccharide-Induced Inflammation
Abstract Lipopolysaccharide (LPS)-induced inflammation causes massive threatening diseases, such as sepsis, acute lung injury and multiple organ dysfunction syndrome. Efficient treatment to prevent inflammation is crucial in LPS-induced inflammatory diseases. Heat-clearing Chinese medicines (CMs) have been used to ameliorate LPS-induced inflammation in China for centuries. Heat-clearing CMs regulate inflammatory pathways, thereby inhibiting the release of inflammatory factors....
Latest Results for Chinese Journal of Integrative Medicine
47m
Implications for Online Management: Two Cases with COVID-19
Telemedicine and e-Health, Ahead of Print.
Telemedicine and e-Health - Table of Contents
49m
Immunological and Clinical Phenotyping in Primary Antibody Deficiencies: a Growing Disease Spectrum
Abstract Purpose Although common variable immunodeficiency (CVID) is considered the most prevalent symptomatic primary antibody deficiency (PAD), there is a population with symptomatic PADs that do not meet criteria for CVID. We analyzed clinical and immunological profiles of patients with different PADs to better understand the differences and similarities between CVID and other PADs. ...
Latest Results
3h
Zum Beitrag „Ambulant erworbene Pneumonie“
Dtsch med Wochenschr 2020; 145: 489-489DOI: 10.1055/a-1106-5053© Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Full text
DMW - Deutsche Medizinische Wochenschrift
3h
Stellungnahme der DGIM zum Referentenentwurf zur DiGAV
Dtsch med Wochenschr 2020; 145: 502-502DOI: 10.1055/a-1130-6974© Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Full text
DMW - Deutsche Medizinische Wochenschrift
3h
Elektive endovaskuläre versus operative Therapie des Bauchaortenaneurysmas – aktuelle Langzeitdaten
Dtsch med Wochenschr 2020; 145: 418-422DOI: 10.1055/a-0956-4325 Aktuelle Studien 4 klinische Studien haben die endovaskuläre Versorgung (endovascular aneurysm bzw. aortic repair, EVAR) und die offen chirurgische Therapie (open repair, OR) des Bauchaortenaneurysmas (BAA) randomisiert prospektiv verglichen: Chronologisch sind dies EVAR 1 (UK), DREAM (Niederlande), OVER (USA) und ACE (Frankreich). Alle 4 Studien sind der Frage nachgegangen, ob die frühe postoperative Überlegenheit der endovaskulären...
DMW - Deutsche Medizinische Wochenschrift
3h
Europaweiter Austausch und Inspiration – ESIM Winter School in Levi, Finnland
Dtsch med Wochenschr 2020; 145: 493-493DOI: 10.1055/a-1141-6948© Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Full text
DMW - Deutsche Medizinische Wochenschrift
3h
Metabolische Chirurgie bei Typ-2-Diabetes?
Dtsch med Wochenschr 2020; 145: 423-428DOI: 10.1055/a-0957-9878 Indikationsstellung Unter metabolischer Chirurgie wird die nicht ausschließlich gewichtsabhängige chirurgische Therapie von Stoffwechselerkrankungen verstanden, deren Ziel unter anderem die Verbesserung der Hyperglykämie ist. Nach der seit 2018 gültigen S3-Leitlinie „Chirurgie der Adipositas und metabolischer Erkrankungen“ kann die Indikation zur metabolischen Chirurgie bei Menschen mit Typ-2-Diabetes und einem BMI ≥ 35 kg/m²...
DMW - Deutsche Medizinische Wochenschrift
3h
59-jährige Patientin mit plantaren Pusteln und Brustschmerzen
Dtsch med Wochenschr 2020; 145: 481-482DOI: 10.1055/a-1120-4239© Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Full text
DMW - Deutsche Medizinische Wochenschrift
3h
Barrett-Ösophagus – Update zu klinischem Management und Therapien
Dtsch med Wochenschr 2020; 145: 429-435DOI: 10.1055/a-0968-6699 Pathogenese Adenokarzinome des Ösophagus sind denen des Magens sehr ähnlich und entstehen mit hoher Wahrscheinlichkeit im Bereich der Kardia im Magen, von wo aus proliferierende Zellen in den Ösophagus expandieren und dort zunächst benigne „Barrett-Schleimhautinseln“ bilden. Eine hinzukommende genomische Instabilität führt zur klonalen Evolution bestimmter Zellen, die zur Entwicklung eines Adenokarzinoms führen kann. ...
DMW - Deutsche Medizinische Wochenschrift
3h
Leben retten – nur eine rasche „Notbremsung“ kann jetzt helfen
Dtsch med Wochenschr 2020; 145: 491-492DOI: 10.1055/a-1130-6783© Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Full text
DMW - Deutsche Medizinische Wochenschrift
3h
Das Refeeding-Syndrom beim älteren Patienten
Dtsch med Wochenschr 2020; 145: 436-441DOI: 10.1055/a-0955-0094 Pathophysiologie Trotz mangelnder Aufnahme werden die Serumspiegel von Kalium, Magnesium und Phosphat durch homöostatische Mechanismen lange Zeit zulasten der intrazellulären Konzentrationen aufrechterhalten. Die okkulte intrazelluläre Verarmung dieser Elektrolyte führt bei abrupter Wiederaufnahme der Ernährung und der damit verbundenen Insulinausschüttung zu einem raschen Einstrom dieser Elektrolyte in die Zelle und damit...
DMW - Deutsche Medizinische Wochenschrift
3h
Die Führungskräfte von morgen
Dtsch med Wochenschr 2020; 145: 497-497DOI: 10.1055/a-1130-6913© Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Full text
DMW - Deutsche Medizinische Wochenschrift
3h
Gallengangs- und Gallenblasenkarzinome: auf dem Weg zur personalisierten Therapie
Dtsch med Wochenschr 2020; 145: 442-446DOI: 10.1055/a-0974-9694 Nomenklatur: Überbegriff maligne biliäre Tumoren Unter dem Begriff maligne biliäre Tumoren (engl. biliary tract cancer) werden weiterhin Karzinome der intra- und extrahepatischen Gallengänge und der Gallenblase zusammengefasst, deren auch molekularpathologische Unterschiede immer besser verstanden werden. Als klinisch relevante Veränderungen wurden neben einer Mikrosatelliteninstabilität bisher IDH-1- und BRAF-Mutationen,...
DMW - Deutsche Medizinische Wochenschrift
3h

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