Antibiotics, Vol. 8, Pages 153: The Contribution of Efflux Pumps in Mycobacterium abscessus Complex Resistance to Clarithromycin Antibiotics doi: 10.3390/antibiotics8030153 Authors: Júlia S. Vianna Diana Machado Ivy B. Ramis Fábia P. Silva Dienefer V. Bierhals Michael Andrés Abril Andrea von Groll Daniela F. Ramos Maria Cristina S. Lourenço Miguel Viveiros Pedro E. Almeida da Silva The basis of drug resistance in Mycobacterium abscessus is still poorly understood....
Wed Sep 18, 2019 03:00
Antioxidants, Vol. 8, Pages 413: Glutathione Induced Immune-Stimulatory Activity by Promoting M1-Like Macrophages Polarization via Potential ROS Scavenging Capacity Antioxidants doi: 10.3390/antiox8090413 Authors: Da Hye Kwon Hyesook Lee Cheol Park Su-Hyun Hong Sang Hoon Hong Gi-Young Kim Hee-Jae Cha Suhkmann Kim Heui-Soo Kim Hye-Jin Hwang Yung Hyun Choi The present study investigated the immunomodulatory activity of reduced glutathione (GSH) by assessment...
Wed Sep 18, 2019 03:00
Antioxidants, Vol. 8, Pages 412: Metabolic Profiling of Buddleia indica Leaves using LC/MS and Evidence of their Antioxidant and Hepatoprotective Activity Using Different In Vitro and In Vivo Experimental Models Antioxidants doi: 10.3390/antiox8090412 Authors: Fadia S. Youssef Mohamed L. Ashour Hesham A. El-Beshbishy Abdel Nasser B. Singab Michael Wink LC-ESI-MS (Liquid Chromatography coupled with Electrospray Ionization Mass Spectrometry profiling of a methanol extract from...
Wed Sep 18, 2019 03:00
Antioxidants, Vol. 8, Pages 414: Catalase-Like Antioxidant Activity is Unaltered in Hypochlorous Acid Oxidized Horse Heart Myoglobin Antioxidants doi: 10.3390/antiox8090414 Authors: Gulfam Ahmad Belal Chami Mary El Kazzi Xiaosuo Wang Maria Tereza S. Moreira Natasha Hamilton Aung Min Maw Thomas W. Hambly Paul K. Witting Activated neutrophils release myeloperoxidase that produces the potent oxidant hypochlorous acid (HOCl). Exposure of the oxygen transport protein...
Wed Sep 18, 2019 03:00
Antioxidants, Vol. 8, Pages 410: Diallyl Trisulfide Protects Rat Brain Tissue against the Damage Induced by Ischemia-Reperfusion through the Nrf2 Pathway Antioxidants doi: 10.3390/antiox8090410 Authors: Carlos A. Silva-Islas María E. Chánez-Cárdenas Diana Barrera-Oviedo Alma Ortiz-Plata José Pedraza-Chaverri Perla D. Maldonado Stroke is a public health problem due to its high mortality and disability rates; despite these, the pharmacological treatments are limited. Oxidative...
Wed Sep 18, 2019 03:00
Antioxidants, Vol. 8, Pages 411: d-Cysteine-Induced Rapid Root Abscission in the Water Fern Azolla Pinnata: Implications for the Linkage between d-Amino Acid and Reactive Sulfur Species (RSS) in Plant Environmental Responses Antioxidants doi: 10.3390/antiox8090411 Authors: Hideo Yamasaki Masahiro P. Ogura Katsumi A. Kingjoe Michael F. Cohen Reactive Oxygen Species (ROS) and Reactive Nitrogen Species (RNS) have been proposed as universal signaling molecules in plant stress responses....
Wed Sep 18, 2019 03:00
Antioxidants, Vol. 8, Pages 409: Salivary FRAP as A Marker of Chronic Kidney Disease Progression in Children Antioxidants doi: 10.3390/antiox8090409 Authors: Mateusz Maciejczyk Julita Szulimowska Katarzyna Taranta-Janusz Katarzyna Werbel Anna Wasilewska Anna Zalewska Chronic kidney disease (CKD) is one of the most common modern-age diseases in children. Kidney failure does not reveal any symptoms for a long time; therefore, new biomarkers are sought, preferably those reflecting...
Wed Sep 18, 2019 03:00
Antioxidants, Vol. 8, Pages 408: Endogenous and Exogenous Melatonin Exposure Attenuates Hepatic MT1 Melatonin Receptor Protein Expression in Rat Antioxidants doi: 10.3390/antiox8090408 Authors: Alexander M. Mathes Paul Heymann Christian Ruf Ragnar Huhn Jochen Hinkelbein Thomas Volk Tobias Fink Melatonin receptors are highly relevant for the hepatoprotective effects of the pineal hormone melatonin after experimental hemorrhagic shock in rats. In this study, we sought...
Wed Sep 18, 2019 03:00
Arts, Vol. 8, Pages 121: Between the Art Canon and the Margins: Historicizing Technology-Reliant Art via Curatorial Practice Arts doi: 10.3390/arts8030121 Authors: Elena Papadaki This article explores curatorial practice that has technology-reliant works at its epicentre, arguing that for an efficient methodology to historicize the latter there needs to be a reconfiguration of the curatorial scope and a holistic approach to viewing and documenting exhibitions. Based on theoretical research...
Wed Sep 18, 2019 03:00
Atmosphere, Vol. 10, Pages 561: Evolution of Turbulence in the Kelvin–Helmholtz Instability in the Terrestrial Magnetopause Atmosphere doi: 10.3390/atmos10090561 Authors: Francesca Di Mare Luca Sorriso-Valvo Alessandro Retinò Francesco Malara Hiroshi Hasegawa The dynamics occurring at the terrestrial magnetopause are investigated by using Geotail and THEMIS spacecraft data of magnetopause crossings during ongoing Kelvin–Helmholtz instability. Properties of plasma...
Wed Sep 18, 2019 03:00
Atmosphere, Vol. 10, Pages 560: Deep Random Subspace Learning: A Spatial-Temporal Modeling Approach for Air Quality Prediction Atmosphere doi: 10.3390/atmos10090560 Authors: Xiaotong Sun Wei Xu Decrease in air quality is one of the most crucial threats to human health. There is an imperative and necessary need for more accurate air quality prediction. To meet this need, we propose a novel long short-term memory-based deep random subspace learning (LSTM-DRSL) framework for air quality...
Wed Sep 18, 2019 03:00
Atmosphere, Vol. 10, Pages 559: Evaluation of Different WRF Parametrizations over the Region of Iași with Remote Sensing Techniques Atmosphere doi: 10.3390/atmos10090559 Authors: Iulian-Alin Roșu Silvia Ferrarese Irina Radinschi Vasilica Ciocan Marius-Mihai Cazacu This article aims to present an evaluation of the Weather Research and Forecasting (WRF) model with multiple instruments when applied to a humid continental region, in this case, the region around the city of Iași,...
Wed Sep 18, 2019 03:00
Atmosphere, Vol. 10, Pages 558: Climate Change Influences of Temporal and Spatial Drought Variation in the Andean High Mountain Basin Atmosphere doi: 10.3390/atmos10090558 Authors: Dario Zhiña Martín Montenegro Lisseth Montalván Daniel Mendoza Juan Contreras Lenin Campozano Alex Avilés Climate change threatens the hydrological equilibrium with severe consequences for living beings. In that respect, considerable differences in drought features are expected, especially...
Wed Sep 18, 2019 03:00
Behavioral Sciences, Vol. 9, Pages 101: Study Design and Protocol to Assess Fruit and Vegetable Waste at School Lunches Behavioral Sciences doi: 10.3390/bs9090101 Authors: Allison Marshall Gregory Bounds Krista Patlovich Christine Markham Alicia Farhat Nan Cramer Amanda Oceguera Travis Croom Jamie Carrillo Shreela Sharma This paper has two main aims: (1) to describe the design, implementation, and testing of a protocol to assess longitudinal changes in F&V...
Wed Sep 18, 2019 03:00
Biology, Vol. 8, Pages 68: Biomass and Astaxanthin Productivities of Haematococcus pluvialis in an Angled Twin-Layer Porous Substrate Photobioreactor: Effect of Inoculum Density and Storage Time Biology doi: 10.3390/biology8030068 Authors: Thanh-Tri Do Binh-Nguyen Ong Minh-Ly Nguyen Tran Doan Nguyen Michael Melkonian Hoang-Dung Tran The microalga Haematococcus pluvialis is mainly cultivated in suspended systems for astaxanthin production. Immobilized cultivation on a Twin-Layer...
Wed Sep 18, 2019 03:00
Biomolecules, Vol. 9, Pages 504: Integrative Analysis of the Core Fruit Lignification Toolbox in Pear Reveals Targets for Fruit Quality Bioengineering Biomolecules doi: 10.3390/biom9090504 Authors: Yunpeng Cao Xiaoxu Li Lan Jiang Stone cell content is an important factor affecting pear fruit flavor. Lignin, a major component of pear stone cells, hinders the quality and value of commercial fruit. The completion of the Chinese white pear (Pyrus bretschneideri) genome sequence provides...
Wed Sep 18, 2019 03:00
Biomolecules, Vol. 9, Pages 503: G-Protein-Coupled Estrogen Receptor (GPER)-Specific Agonist G1 Induces ER Stress Leading to Cell Death in MCF-7 Cells Biomolecules doi: 10.3390/biom9090503 Authors: Diep-Khanh Ho Vo Roland Hartig Sönke Weinert Johannes Haybaeck Norbert Nass The G-protein-coupled estrogen receptor (GPER) mediates rapid non-genomic effects of estrogen. Although GPER is able to induce proliferation, it is down-regulated in breast, ovarian and colorectal cancer....
Wed Sep 18, 2019 03:00
Biomolecules, Vol. 9, Pages 501: Immunomodulatory Functions of the Human Cathelicidin LL-37 (aa 13–31)-Derived Peptides are Associated with Predicted α-Helical Propensity and Hydrophobic Index Biomolecules doi: 10.3390/biom9090501 Authors: Mahadevappa Hemshekhar Sana Faiyaz Ka-Yee Grace Choi Oleg V. Krokhin Neeloffer Mookherjee The anti-endotoxin activity of the cationic peptide LL-37 and its derivative IG-19 is attributed to electrostatic interaction of the peptides’...
Wed Sep 18, 2019 03:00
Biomolecules, Vol. 9, Pages 502: Noncovalent Immobilization of Yarrowia lipolytica Lipase on Dendritic-Like Amino Acid-Functionalized Silica Nanoparticles Biomolecules doi: 10.3390/biom9090502 Authors: Zahra Fathi Esmail Doustkhah Golamhossein Ebrahimipour Farshad Darvishi Immobilization of enzymes is a promising approach for the cost-effective application of enzymes. Among others, noncovalent but unleachable approaches for immobilization are one of the most favorable and crucial...
Wed Sep 18, 2019 03:00
Biomolecules, Vol. 9, Pages 499: Creation of Cybrid Cultures Containing mtDNA Mutations m.12315G>A and m.1555G>A, Associated with Atherosclerosis Biomolecules doi: 10.3390/biom9090499 Authors: Margarita A. Sazonova Vasily V. Sinyov Anastasia I. Ryzhkova Marina D. Sazonova Zukhra B. Khasanova Tatiana P. Shkurat Vasily P. Karagodin Alexander N. Orekhov Igor A. Sobenin In the present work, a pilot creation of four cybrid cultures with high heteroplasmy level...
Wed Sep 18, 2019 03:00
Biomolecules, Vol. 9, Pages 500: Effects of Fludioxonil on the Cell Growth and Apoptosis in T and B Lymphocytes Biomolecules doi: 10.3390/biom9090500 Authors: Gun-Hwi Lee Kyung-A Hwang Kyung-Chul Choi Fludioxonil is fungicide used in agriculture, which is present in fruits and vegetables. In this study, the effects of fludioxonil on human immune cell viability, apoptosis, cell cycle arrest, and mitochondrial membrane potential were examined in human immune cells, such as Jurkat...
Wed Sep 18, 2019 03:00
Brain Sciences, Vol. 9, Pages 239: Postural Instability in Parkinson’s Disease: A Review Brain Sciences doi: 10.3390/brainsci9090239 Authors: Bhavana Palakurthi Sindhu Preetham Burugupally Parkinson’s disease (PD) is a heterogeneous progressive neurodegenerative disorder, which typically affects older adults; it is predicted that by 2030 about 3% of the world population above 65 years of age is likely to be affected. At present, the diagnosis of PD is clinical, subjective,...
Wed Sep 18, 2019 03:00
Brain Sciences, Vol. 9, Pages 238: Targeting the Mitochondrial Pyruvate Carrier for Neuroprotection Brain Sciences doi: 10.3390/brainsci9090238 Authors: Bor Luen Tang The mitochondrial pyruvate carriers mediate pyruvate import into the mitochondria, which is key to the sustenance of the tricarboxylic cycle and oxidative phosphorylation. However, inhibition of mitochondria pyruvate carrier-mediated pyruvate transport was recently shown to be beneficial in experimental models of neurotoxicity...
Wed Sep 18, 2019 03:00
Brain Sciences, Vol. 9, Pages 237: Mental Imagery and Acute Exercise on Episodic Memory Function Brain Sciences doi: 10.3390/brainsci9090237 Authors: Lauren Johnson Jie Yao Liye Zou Tao Xiao Paul D. Loprinzi Mental imagery is used extensively in the sporting domain. It is used for performance-enhancement purposes, arousal regulation, affective and cognitive modification, and rehabilitation purposes. The purpose of this experiment was to evaluate whether acute exercise and...
Wed Sep 18, 2019 03:00
Cancers, Vol. 11, Pages 1386: Reply to Comment on “Osteopontin, Macrophage Migration Inhibitory Factor and Anti-Interleukin-8 Autoantibodies Complement CA125 for Detection of Early Stage Ovarian Cancer” Cancers 2019, 11, 596: Markers for Early Detection of Ovarian Cancer Cancers doi: 10.3390/cancers11091386 Authors: Jing Guo Zhen Lu Robert C. Bast We appreciate Mor et al [...]
Wed Sep 18, 2019 03:00
Cancers, Vol. 11, Pages 1395: Management of Small Bowel Neuroendocrine Tumors Cancers doi: 10.3390/cancers11091395 Authors: Larouche Akirov Alshehri Ezzat Several important landmark trials have reshaped the landscape of non-surgical management of small bowel neuroendocrine tumors over the last few years, with the confirmation of the antitumor effect of somatostatin analogue therapy in PROMID and CLARINET trials as well as the advent of therapies with significant potential...
Wed Sep 18, 2019 03:00
Cancers, Vol. 11, Pages 1393: Should Tumor Infiltrating Lymphocytes, Androgen Receptor, and FOXA1 Expression Predict the Clinical Outcome in Triple Negative Breast Cancer Patients? Cancers doi: 10.3390/cancers11091393 Authors: Anita Mangia Concetta Saponaro Alessandro Vagheggini Giuseppina Opinto Matteo Centonze Chiara Vicenti Ondina Popescu Maria Pastena Francesco Giotta Nicola Silvestris Tumor-infiltrating lymphocytes (TILs) are a valuable indicator of the...
Wed Sep 18, 2019 03:00
Cancers, Vol. 11, Pages 1392: TWIST1 Heterodimerization with E12 Requires Coordinated Protein Phosphorylation to Regulate Periostin Expression Cancers doi: 10.3390/cancers11091392 Authors: Svetlana A. Mikheeva Nathan D. Camp Lei Huang Antrix Jain Sung Yun Jung Naze G. Avci Mari Tokita Alejandro Wolf-Yadlin Jing Zhang Stephen J. Tapscott Robert C. Rostomily Andrei M. Mikheev Diffuse invasion into adjacent brain matter by glioblastoma (GBM) is largely responsible...
Wed Sep 18, 2019 03:00
Cancers, Vol. 11, Pages 1394: Interleukin4Rα (IL4Rα) and IL13Rα1 Are Associated with the Progress of Renal Cell Carcinoma through Janus Kinase 2 (JAK2)/Forkhead Box O3 (FOXO3) Pathways Cancers doi: 10.3390/cancers11091394 Authors: Mi-Ae Kang Jongsung Lee Sang Hoon Ha Chang Min Lee Kyoung Min Kim Kyu Yun Jang See-Hyoung Park Specific kinds of interleukin (IL) receptors are known to mediate lymphocyte proliferation and survival. However, recent reports have suggested...
Wed Sep 18, 2019 03:00
Cancers, Vol. 11, Pages 1388: BRAF Inhibitors in Thyroid Cancer: Clinical Impact, Mechanisms of Resistance and Future Perspectives Cancers doi: 10.3390/cancers11091388 Authors: Fabiana Crispo Tiziana Notarangelo Michele Pietrafesa Giacomo Lettini Giovanni Storto Alessandro Sgambato Francesca Maddalena Matteo Landriscina The Kirsten rat sarcoma viral oncogene homolog (RAS)/v-raf-1 murine leukemia viral oncogene homolog 1 (RAF)/mitogen-activated protein kinase 1 (MAPK)...
Wed Sep 18, 2019 03:00
Cancers, Vol. 11, Pages 1390: Docetaxel Combined with Thymoquinone Induces Apoptosis in Prostate Cancer Cells via Inhibition of the PI3K/AKT Signaling Pathway Cancers doi: 10.3390/cancers11091390 Authors: Santosh Kumar Singh Tejumola Apata Jennifer B. Gordetsky Rajesh Singh Toxicity and the development of resistance by cancer cells are impediments for docetaxel (DTX), a primary drug for treating prostate cancer (PCa). Since the combination of DTX with natural compounds can increase...
Wed Sep 18, 2019 03:00
Cancers, Vol. 11, Pages 1389: Heat Shock Proteins and Ovarian Cancer: Important Roles and Therapeutic Opportunities Cancers doi: 10.3390/cancers11091389 Authors: Abdullah Hoter Hassan Y. Naim Ovarian cancer is a serious cause of death in gynecological oncology. Delayed diagnosis and poor survival rates associated with late stages of the disease are major obstacles against treatment efforts. Heat shock proteins (HSPs) are stress responsive molecules known to be crucial in many cancer...
Wed Sep 18, 2019 03:00
Cancers, Vol. 11, Pages 1391: Pheochromocytoma (PHEO) and Paraganglioma (PGL) Cancers doi: 10.3390/cancers11091391 Authors: Karel Pacak David Taïeb This series of 23 articles (17 original articles, six reviews) is presented by international leaders in pheochromocytoma and paraganglioma (PPGL) [...]
Wed Sep 18, 2019 03:00
Cancers, Vol. 11, Pages 1387: Prognostic Factors for Event-Free Survival in Pediatric Patients with Hepatoblastoma Based on the 2017 PRETEXT and CHIC-HS Systems Cancers doi: 10.3390/cancers11091387 Authors: Hee Mang Yoon Jisun Hwang Kyung Won Kim Jung-Man Namgoong Dae Yeon Kim Kyung-Nam Koh Hyery Kim Young Ah Cho This study aimed to evaluate the prognostic value of variables used in the 2017 PRE-Treatment EXTent of tumor (PRETEXT) system and the Children’s...
Wed Sep 18, 2019 03:00
Cells, Vol. 8, Pages 1105: Cellular Stress Responses in Radiotherapy Cells doi: 10.3390/cells8091105 Authors: Kim Lee Seo Kim Kim Kim Kang Seong Youn Youn Radiotherapy is one of the major cancer treatment strategies. Exposure to penetrating radiation causes cellular stress, directly or indirectly, due to the generation of reactive oxygen species, DNA damage, and subcellular organelle damage and autophagy. These radiation-induced damage responses cooperatively...
Wed Sep 18, 2019 03:00
Cells, Vol. 8, Pages 1103: Understanding the Modus Operandi of MicroRNA Regulatory Clusters Cells doi: 10.3390/cells8091103 Authors: Arthur C. Oliveira Luiz A. Bovolenta Lucas Alves Lucas Figueiredo Amanda O. Ribeiro Vinicius F. Campos Ney Lemke Danillo Pinhal MicroRNAs (miRNAs) are non-coding RNAs that regulate a wide range of biological pathways by post-transcriptionally modulating gene expression levels. Given that even a single miRNA may simultaneously control...
Wed Sep 18, 2019 03:00
Cells, Vol. 8, Pages 1104: Interleukin 21 Receptor/Ligand Interaction Is Linked to Disease Progression in Pancreatic Cancer Cells doi: 10.3390/cells8091104 Authors: Linnebacher Mayer Marnet Bergmann Herpel Revia Yin Liu Hackert Giese Herr Gaida Pancreatic ductal adenocarcinoma (PDAC) displays a marked fibro-inflammatory microenvironment in which infiltrated immune cells fail to eliminate the tumor cells and often—rather paradoxically—promote...
Wed Sep 18, 2019 03:00
Cells, Vol. 8, Pages 1102: Trends and Challenges in Tumor Anti-Angiogenic Therapies Cells doi: 10.3390/cells8091102 Authors: József Jászai Mirko H.H. Schmidt Excessive abnormal angiogenesis plays a pivotal role in tumor progression and is a hallmark of solid tumors. This process is driven by an imbalance between pro- and anti-angiogenic factors dominated by the tissue hypoxia-triggered overproduction of vascular endothelial growth factor (VEGF). VEGF-mediated signaling has quickly...
Wed Sep 18, 2019 03:00
Cells, Vol. 8, Pages 1101: Increased Glycolysis and Higher Lactate Production in Hyperglycemic Myotubes Cells doi: 10.3390/cells8091101 Authors: Jenny Lund D. Margriet Ouwens Marianne Wettergreen Siril S. Bakke G. Hege Thoresen Vigdis Aas Previous studies have shown that chronic hyperglycemia impairs glucose and fatty acid oxidation in cultured human myotubes. To further study the hyperglycemia-induced suppression of oxidation, lactate oxidation, mitochondrial function...
Wed Sep 18, 2019 03:00
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