Biomolecules, Vol. 9, Pages 453: Curcumin Attenuates Lead-Induced Cerebellar Toxicity in Rats via Chelating Activity and Inhibition of Oxidative Stress Biomolecules doi: 10.3390/biom9090453 Authors: Kabeer Abubakar Maryam Muhammad Mailafiya Abubakar Danmaigoro Samaila Musa Chiroma Ezamin Bin Abdul Rahim Md Zuki Abu Bakar @ Zakaria Lead (Pb) is a toxic, environmental heavy metal that induces serious clinical defects in all organs, with the nervous system being its primary...
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Molecules, Vol. 24, Pages 3243: Reviewing HIV-1 Gag Mutations in Protease Inhibitors Resistance: Insights for Possible Novel Gag Inhibitor Designs Molecules doi: 10.3390/molecules24183243 Authors: Chinh Tran-To Su Darius Wen-Shuo Koh Samuel Ken-En Gan HIV protease inhibitors against the viral protease are often hampered by drug resistance mutations in protease and in the viral substrate Gag. To overcome this drug resistance and inhibit viral maturation, targeting Gag alongside...
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Molecules, Vol. 24, Pages 3242: Evaluation of Elastin-Like Polypeptides for Tumor Targeted Delivery of Doxorubicin to Glioblastoma Molecules doi: 10.3390/molecules24183242 Authors: Sonja Dragojevic Rebecca Mackey Drazen Raucher To increase treatment efficiency for glioblastoma, we have developed a system to selectively deliver chemotherapeutic doxorubicin (Dox) to Glioblastoma (GBM) tumors. This carrier is based on elastin-like polypeptide (ELP), which is soluble at physiological...
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Molecules, Vol. 24, Pages 3244: A Secreted Phospholipase A2 Induces Formation of Smooth Muscle Foam Cells Which Transdifferentiate to Macrophage-Like State Molecules doi: 10.3390/molecules24183244 Authors: Karina Cristina Giannotti Sönke Weinert Mariana Nascimento Viana Elbio Leiguez Thaís L. S. Araujo Francisco R. M. Laurindo Bruno Lomonte Rüdiger Braun-Dullaeus Catarina Teixeira Vascular smooth muscle cells (VSMCs) loaded with lipid droplets (LDs) are markers...
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Nutrients, Vol. 11, Pages 2121: Alcohol Consumption and Risk of Chronic Kidney Disease: A Nationwide Observational Cohort Study Nutrients doi: 10.3390/nu11092121 Authors: Yun-Ju Lai Yu-Yen Chen Yu-Kai Lin Chu-Chieh Chen Yung-Feng Yen Chung-Yeh Deng Alcohol consumption is a significant public health issue worldwide. The rat model and epidemiological studies have both reported conflicting results about the effects of alcohol on the kidneys. We aimed to explore the relationships...
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