Επιστήμονες από το Πανεπιστήμιο του Τέξας βρήκαν στοιχεία που υποδεικνύουν ότι η αντίσταση στην «ορμόνη της πείνας», τη γκρελίνη που βρίσκεται στον εγκέφαλο, συνδέεται με γνωστικές βλάβες και απώλεια μνήμης, φαινόμενα σχετικά με τη νόσο Αλτσχάιμερ. Τα ευρήματα της έρευνας που δημοσιεύθηκε στο Science Translational Medicine υποδεικνύουν επίσης μια πιθανή θεραπευτική στρατηγική για την νευροεκφυλιστική διαταραχή που δεν επιδέχεται θεραπείας. Η γκρελίνη παράγεται στο στομάχι και στέλνει σήματα στον...
Wed Sep 04, 2019 16:35
3461 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2019/09/04PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Sep 04, 2019 15:45
Ένα νέο ρόλο του ενζύμου τελομεράση φαίνεται πως ανακάλυψαν ερευνητές από το Πανεπιστήμιο του Μέριλαντ και το Αμερικανικό Ινστιτούτο για την Υγεία. Η μέχρι τώρα γνωστή δράση της τελομεράσης στον φυσιολογικό ιστό ήταν να προστατεύει τα κύτταρα που διαιρούνται ομαλά όπως τα εμβρυονικά και σπερματικά κύτταρα, τα ενήλικα βλαστοκύτταρα και τα ανοσοκύτταρα. Στις περιπτώσεις των υπολοίπων κυττάρων θεωρείτο πως η τελομεράση ήταν ανενεργή, με μοναδική εξαίρεση τους καρκινικούς όγκους όπου φαίνεται ότι προωθεί...
Wed Sep 04, 2019 12:29
61 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human homeostasis These pubmed results were generated on 2019/09/04PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Sep 04, 2019 15:19
139 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: ALCOHOL These pubmed results were generated on 2019/09/04PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Sep 04, 2019 15:07
154 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human physiology These pubmed results were generated on 2019/09/04PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Sep 04, 2019 14:52
Related ArticleslncRNA HOTAIR upregulates autophagy to promote apoptosis and senescence of nucleus pulposus cells. J Cell Physiol. 2019 Sep 03;: Authors: Zhan S, Wang K, Xiang Q, Song Y, Li S, Liang H, Luo R, Wang B, Liao Z, Zhang Y, Yang C Abstract Intervertebral disc degeneration (IDD) is a complex and chronic disease that involves disc cell senescence, death, and extracellular matrix (ECM) degradation. HOTAIR, a long non-coding RNA (lncRNA) is reportedly...
Wed Sep 04, 2019 16:35
Related ArticlesPIWI-interacting RNA 39980 promotes tumor progression and reduces drug sensitivity in neuroblastoma cells. J Cell Physiol. 2019 Sep 03;: Authors: Roy J, Das B, Jain N, Mallick B Abstract Neuroblastoma (NB) is the leading pediatric cancer known for its heterogeneity and clinical aggressiveness leading to chemoresistance. Recent evidence in small RNA research has led to the discovery of PIWI-interacting RNAs (piRNAs) which work in an orchestrated...
Wed Sep 04, 2019 16:35
Related ArticlesSerine peptidase inhibitor Kazal type III (SPINK3) promotes BRL-3A cell proliferation by targeting the PI3K-AKT signaling pathway. J Cell Physiol. 2019 Sep 02;: Authors: Chang C, Xie J, Yang Q, Yang J, Luo Y, Xi L, Guo J, Yang G, Jin W, Wang G Abstract The serine protease inhibitor, Kazal type III (SPINK3), is a trypsin inhibitor associated with liver disease, which highly overexpresses in a variety of cancers. In one of our previous...
Wed Sep 04, 2019 14:30
Related ArticlesA process evaluation of the PLAN-A intervention (Peer-Led physical Activity iNtervention for Adolescent girls). BMC Public Health. 2019 Sep 02;19(1):1203 Authors: Sebire SJ, Banfield K, Jago R, Edwards MJ, Campbell R, Kipping R, Blair PS, Kadir B, Garfield K, Matthews J, Lyons RA, Hollingworth W Abstract BACKGROUND: Few adolescent girls engage in enough physical activity (PA) to meet recommendations and there is a need for new interventions...
Wed Sep 04, 2019 14:28
Related ArticlesEnergy balance-related factors associating with adolescent weight loss intent: evidence from the 2017 National Youth Risk Behavior Survey. BMC Public Health. 2019 Sep 02;19(1):1206 Authors: Burns RD Abstract BACKGROUND: The purpose of this study was to examine specific energy balance-related behaviors (sedentary behaviors, physical activity, and dietary) associating with adolescent weight loss intent using data from the 2017 US Youth...
Wed Sep 04, 2019 14:28
Related ArticlesRising HIV prevalence among men who have sex with men in Nigeria: a trend analysis. BMC Public Health. 2019 Sep 02;19(1):1201 Authors: Eluwa GIE, Adebajo SB, Eluwa T, Ogbanufe O, Ilesanmi O, Nzelu C Abstract BACKGROUND: Men who have sex with men (MSM) are conservatively estimated to be less than 1% of the Nigerian population yet nationally account for about 20% of new HIV infection. We estimated the trend in HIV prevalence and determined...
Wed Sep 04, 2019 14:28
Related ArticlesVaping patterns, nicotine dependence and reasons for vaping among American Indian dual users of cigarettes and electronic cigarettes. BMC Public Health. 2019 Sep 02;19(1):1211 Authors: Rhoades DA, Comiford AL, Dvorak JD, Ding K, Hopkins M, Spicer P, Wagener TL, Doescher MP Abstract BACKGROUND: The American Cancer Society discourages the dual use of electronic cigarettes (ECs) and cigarettes because such use has not resulted in reduced...
Wed Sep 04, 2019 14:28
Related ArticlesA multi-country survey of public support for food policies to promote healthy diets: Findings from the International Food Policy Study. BMC Public Health. 2019 Sep 02;19(1):1205 Authors: Kwon J, Cameron AJ, Hammond D, White CM, Vanderlee L, Bhawra J, Sacks G Abstract BACKGROUND: Poor diet is a significant contributor to the burden of global disease. There are numerous policies available to address poor diets; however, these policies often...
Wed Sep 04, 2019 14:28
Related ArticlesAssociation between intestinal worm infection and malnutrition among rural children aged 9-11 years old in Guizhou Province, China. BMC Public Health. 2019 Sep 02;19(1):1204 Authors: Guan M, Han B Abstract BACKGROUND: Intestinal worm infection adversely impacted child health and was one of the China's largest health burdens. However, yet little was known about associations between intestinal worm infection and malnutrition in school-aged...
Wed Sep 04, 2019 14:28
Related ArticlesFactors associated with consistent condom use: a cross-sectional survey of two Nigerian universities. BMC Public Health. 2019 Sep 02;19(1):1207 Authors: Ajayi AI, Ismail KO, Akpan W Abstract BACKGROUND: Consistent condom use is central to the prevention of transmission of human immunodeficiency virus (HIV) and other sexually transmitted diseases (STDs), especially among young adults. This study drew from a cross-sectional survey of two...
Wed Sep 04, 2019 14:28
Related ArticlesThe association between alcohol, marijuana, illegal drug use and current use of E-cigarette among youth and young adults in Canada: results from Canadian Tobacco, Alcohol and Drugs Survey 2017. BMC Public Health. 2019 Sep 02;19(1):1208 Authors: Mehra VM, Keethakumar A, Bohr YM, Abdullah P, Tamim H Abstract BACKGROUND: E-cigarettes have grown in popularity around the world since 2003. Although marketed as a smoking cessation tool, e-cigarettes...
Wed Sep 04, 2019 14:28
Related ArticlesInfancy weight gain, parental socioeconomic position, and childhood overweight and obesity: a Danish register-based cohort study. BMC Public Health. 2019 Sep 02;19(1):1209 Authors: Rotevatn TA, Overgaard C, Melendez-Torres GJ, Mortensen RN, Ullits LR, Høstgaard AMB, Torp-Pedersen C, Bøggild H Abstract BACKGROUND: Rapid infant weight gain (RIWG) is a very strong predictor of childhood overweight and obesity (COO). Socioeconomic position...
Wed Sep 04, 2019 14:28
Related ArticlesThe geography and economics of forgoing medical examinations or therapeutic treatments in Italy during the economic crisis. BMC Public Health. 2019 Sep 02;19(1):1202 Authors: Petrelli A, Rosano A, Rossi A, Mirisola C, Cislaghi C Abstract BACKGROUND: In Italy, the number of individuals who have forgone medical examinations or treatments for economic reasons is one of the highest in Europe. During the global economic crisis of 2008, the...
Wed Sep 04, 2019 14:28
Related ArticlesSexual practices, sexual behavior and HIV risk profile of key populations in Nigeria. BMC Public Health. 2019 Sep 02;19(1):1210 Authors: Ochonye B, Folayan MO, Fatusi AO, Bello BM, Ajidagba B, Emmanuel G, Umoh P, Yusuf A, Jaiyebo T Abstract BACKGROUND: There is little evidence on the need for differentiated HIV prevention services for men who have sex with men (MSM), female sex workers (FSW) and people who inject drugs (PWID in Nigeria....
Wed Sep 04, 2019 14:28
Related ArticlesA systematic review of depression and anxiety in medical students in China. BMC Med Educ. 2019 Sep 02;19(1):327 Authors: Mao Y, Zhang N, Liu J, Zhu B, He R, Wang X Abstract BACKGROUND: Medical students in China face severe depression and anxiety because of their difficult circumstances, such as the long length of schooling, academic pressure, and the stress of clinical practice. Although there have been many empirical studies about depression...
Wed Sep 04, 2019 13:55
Related ArticlesCytokit: a single-cell analysis toolkit for high dimensional fluorescent microscopy imaging. BMC Bioinformatics. 2019 Sep 02;20(1):448 Authors: Czech E, Aksoy BA, Aksoy P, Hammerbacher J Abstract BACKGROUND: Multiplexed in-situ fluorescent imaging offers several advantages over single-cell assays that do not preserve the spatial characteristics of biological samples. This spatial information, in addition to morphological properties and...
Wed Sep 04, 2019 13:51
Related ArticlesSigsPack, a package for cancer mutational signatures. BMC Bioinformatics. 2019 Sep 02;20(1):450 Authors: Schumann F, Blanc E, Messerschmidt C, Blankenstein T, Busse A, Beule D Abstract BACKGROUND: Mutational signatures are specific patterns of somatic mutations introduced into the genome by oncogenic processes. Several mutational signatures have been identified and quantified from multiple cancer studies, and some of them have been linked...
Wed Sep 04, 2019 13:51
Related ArticlesAnalyzing the regulation of miRNAs on protein-protein interaction network in Hodgkin lymphoma. BMC Bioinformatics. 2019 Sep 02;20(1):449 Authors: Lei H, Liu W, Si J, Wang J, Zhang T Abstract BACKGROUND: Hodgkin Lymphoma (HL) is a type of aggressive malignancy in lymphoma that has high incidence in young adults and elderly patients. Identification of reliable diagnostic markers and efficient therapeutic targets are especially important...
Wed Sep 04, 2019 13:51
3461 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2019/09/04PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Sep 04, 2019 13:47
Όσες περισσότερες «έξυπνες» ηλεκτρονικές συσκευές έχει κανείς στο σπίτι του, όπως π.χ. τα ηχεία με τεχνητή νοημοσύνη, τόσο λιγότερο ικανοποιημένος τείνει να νιώσει με τη νέα τεχνολογία. Αυτό είναι το συμπέρασμα μίας νέας έρευνας Ελλήνων ερευνητών της διασποράς, που εστιάζει στα νέα «γκάτζετ» των «έξυπνων» σπιτιών (smart homes), διαπιστώνοντας ότι τελικά οι περισσότεροι άνθρωποι αισθάνονται μάλλον καλύτερα, όταν έχουν λίγες μόνο τέτοιες συσκευές γύρω τους. Η μελέτη βρήκε, επίσης, ότι η ηλικία δεν...
Wed Sep 04, 2019 10:11
61 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human homeostasis These pubmed results were generated on 2019/09/04PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Sep 04, 2019 13:14
Related ArticlesOn the loop again: understanding human spinal circuitry through the study of its reflex pathway. J Physiol. 2019 Sep 02;: Authors: Grosprêtre S PMID: 31478200 [PubMed - as supplied by publisher]
Wed Sep 04, 2019 13:06
139 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: ALCOHOL These pubmed results were generated on 2019/09/04PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Sep 04, 2019 13:03
The corresponding author noticed in his published paper that the images (30 weeks, CC, 10, 30 and 50 weeks DG) of fig. 3b are inadvertently duplicated with the images of fig. 3a. Now, these images have been replaced in the corrected panel (Fig. 3b) below.
Wed Sep 04, 2019 03:00
Abstract Growth hormone (GH) is secreted by the anterior pituitary gland and regulates various metabolic processes throughout the body. GH and IGF-1 levels are markedly reduced in older humans, leading some to hypothesize GH supplementation could be a viable “anti-aging” therapy. However, there is still much debate over the benefits and risks of GH administration. While an early study of GH administration reported reduced adiposity and lipid levels and increased bone mineral density,...
Wed Sep 04, 2019 03:00
Αν ένα σχολικό τεστ είναι «μαραθώνιος» και όχι «σπριντ» σε διάρκεια, τα κορίτσια τα καταφέρνουν καλύτερα από ό,τι τα αγόρια, σύμφωνα με μια νέα ισπανο-ολλανδική επιστημονική μελέτη, την πρώτη που κάνει αυτή τη διαπίστωση. Οι επιστήμονες δεν είναι βέβαιοι γιατί συμβαίνει αυτό, αλλά πιθανώς οφείλεται στο ότι τα κορίτσια μπορούν να διατηρήσουν περισσότερο τη συγκέντρωση, την επιμονή και την αυτοπειθαρχία τους. Η νέα μελέτη δείχνει ότι τα κορίτσια είναι καλύτερα από τα συνομήλικα αγόρια στο να διατηρούν...
Wed Sep 04, 2019 09:27
Αμερικανοί ερευνητές ανακάλυψαν ότι έγκυα και θηλάζοντα πειραματόζωα που είχαν σιτιστεί με διατροφή πλούσια σε λιπαρά απέκτησαν απογόνους που μεγαλώνοντας μάθαιναν με βραδύτερο ρυθμό και είχαν διαρκώς μη φυσιολογικά επίπεδα συστατικών απαραίτητων για την υγιή ανάπτυξη του εγκεφάλου και του μεταβολισμού. Στα πειράματα που έκαναν οι ειδικοί της Ιατρικής Σχολής Johns Hopkins και δημοσίευσαν στο Experimental Neurology, έγκυοι αρουραίοι έκαναν επανειλημμένα μια διατροφή όμοια σε λιπαρά με μια κλασσική...
Wed Sep 04, 2019 09:14
Οι αλλαγές στο DNA κατά τη διάρκεια της ζωής ενός ανθρώπου μπορεί να αυξήσουν σημαντικά την ευαλωτότητά του σε καρδιακές παθήσεις και ασθένειες που σχετίζονται με την ηλικία, υποστηρίζει νέα έρευνα από επιστήμονες των Πανεπιστημίων του Εδιμβούργου και της Γλασκώβης που δημοσιεύθηκε στο Current Biology. Κάποιες μεταβολές, γνωστές ως επίκτητες (σωματικές) μεταλλάξεις, μπορούν να επηρεάσουν σημαντικά τον τρόπο με τον οποίο τα αιμοφόρα αγγεία λειτουργούν, ενώ σχετίζονται με τον καρκίνο του αίματος και...
Wed Sep 04, 2019 08:37
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