Publication date: Available online 9 September 2019Source: World NeurosurgeryAuthor(s): John K. Houten, Jordan Pasternack, Robert P. NortonAbstractBackgroundA preponderance of common signs and symptoms of cervical myelopathy (CM) manifest in the upper extremities and include hand numbness, hand clumsiness, and distal upper extremity weakness. Cervical myelopathy presenting without symptoms in the upper extremities is rare and this study aims to better understand the incidence and character of such...
Fri Sep 13, 2019 17:14
Publication date: Available online 10 September 2019Source: World NeurosurgeryAuthor(s): Abdurrahman Çetin, Burcu Biltekin, Sevgin DegirmenciogluAbstractObjectiveThe anticarcinogenic effect of ellagic acid (EA), one of natural phenols of fruits and vegetables, has been investigated in several types of tumors, while the combining effect with Bevacizumab (BEV), a common drug used in the treatment of recurrent glioma, on glioblastoma has never been reported yet. Here, we aimed to observe the combining...
Fri Sep 13, 2019 17:14
Publication date: Available online 10 September 2019Source: World NeurosurgeryAuthor(s): Louis-Marie Terrier, Marc Lévêque, Aymeric AmelotAbstractBackgroundPioneered in 1936 by Portuguese neurologist and politician Egas Moniz, lobotomy was a definitive lesional surgery on the brain, which consisted in splitting white fibers in the frontal lobes. Sixteen years later, the first anti-psychotic medication appeared at Sainte-Anne mental hospital in Paris, brutally reducing the amount of surgical lobotomies...
Fri Sep 13, 2019 17:14
Publication date: Available online 10 September 2019Source: World NeurosurgeryAuthor(s): Walter C. Jean, Trong Huynh, Alexander X. Tai, Daniel R. Felbaum, Hasan R. Syed, Hung M. NgoAbstractBackgroundThe health care expenditure in Vietnam is equivalent to 1% of that in the United States. For most patients with brain arteriovenous malformations (AVM), surgery is the only available treatment modality. This study reports on the outcomes on AVM microsurgery in this resource restricted environment.MethodsThis...
Fri Sep 13, 2019 17:14
Attenuation of white matter damage following Deferoxamine treatment in rats after spinal cord injury
Publication date: Available online 10 September 2019Source: World NeurosurgeryAuthor(s): Jiantao Shi, Rongrui Tang, Yi Zhou, Jishu Xian, Chenghai Zuo, Long Wang, Jie Wang, Hua Feng, Shengli HuAbstractBackgroundand purpose —With little information available on axonal and myelin damage surrounding the contusion, the study of spinal cord injury (SCI) so far has focused on neuronal death. In this study, we investigated the role of iron overload in long-term oligodendroglia death and progressive white...
Fri Sep 13, 2019 17:14
Publication date: Available online 10 September 2019Source: World NeurosurgeryAuthor(s): Akal Sethi, Daniel Cavalcante, D. Ryan OrmondAbstract:Background; Transcallosal microscopic and endoscopic excisions are both well established; approaches to colloid cyst resection; however, there has been no clear consensus; regarding the favored approach.ObjectiveTo perform a systematic review comparing the transcallosal microscopic and endoscopic transcortical approaches for colloid cyst excision.MethodsWe...
Fri Sep 13, 2019 17:14
Publication date: Available online 10 September 2019Source: World NeurosurgeryAuthor(s): Koichi Miki, Hiroshi Abe, Masani Nonaka, Takashi Morishita, Mitsutoshi Iwaasa, Hisatomi Arima, Tooru InoueAbstractBackgroundThe spot sign (SS) in spontaneous intracerebral hemorrhage (sICH) has been reported to be a predictive factor of poor outcome, however, how SS is related with the clinical outcome remain unclear. We aimed to investigate how etiology associated with SS affects the clinical outcome of endoscopic...
Fri Sep 13, 2019 17:14
Publication date: Available online 10 September 2019Source: World NeurosurgeryAuthor(s): Alfio Spina, Filippo Gagliardi, Javier Abarca-Olivas, Michele Bailo, Nicola Boari, Pablo Gonzalez-Lopez, Cristian Gragnaniello, Anthony J. Caputy, Pietro MortiniAbstractObjectiveAnterior craniovertebral junction (CVJ) surgery is still one of the most debated neurosurgical topics. Transoral approach (TOA) has been considered the choice to this region however; it has shown some limitations and a not negligible...
Fri Sep 13, 2019 17:14
Publication date: Available online 10 September 2019Source: World NeurosurgeryAuthor(s): Jiawei Chen, Chongxian Hou, Peng Wang, Yong Yang, Dong ZhouAbstract：ObjectiveThe tumor microenvironment greatly influences tumor formation, invasion, and progression. The ESTIMATE algorithm quantifies stromal and immune components in a tumor, reflecting the tumor microenvironment. This study aimed to explore key prognostic genes in grade II/III glioma microenvironment.MethodsWe obtained stromal/immune scores...
Fri Sep 13, 2019 17:14
Publication date: Available online 10 September 2019Source: World NeurosurgeryAuthor(s): Jeffrey I. Traylor, Rajan Patel, Ahmed Habib, Matthew Muir, Dhiego Chaves de Almeida Bastos, Ganesh Rao, Sujit S. PrabhuAbstractObjectivePosterior fossa tumors are rare in adults and pose a challenge to treat due to the bony contour of the posterior fossa, complex anatomical structures including deep venous sinuses, and the proximity of the fourth ventricle and brain stem. We describe our experience with LITT...
Fri Sep 13, 2019 17:14
Publication date: Available online 10 September 2019Source: World NeurosurgeryAuthor(s): Georges Pfister, Ammar Ghabi, Anne de Carbonnières, Christophe Oberlin, Zoubir Belkheyar, Laurent MathieuAbstractObjectivesThis work sought to elucidate the conditions of direct suturing of sciatic nerve defects in high-degree knee flexion. We aimed to establish a correlation between the defect length, the defect location, the degree of knee flexion, and the eventual need for hip immobilization in extension.MethodsAn...
Fri Sep 13, 2019 17:14
Publication date: Available online 10 September 2019Source: World NeurosurgeryAuthor(s): Arng Jack,Chong, Sher-Wei Lim, Yao-lin Lee, Chung-Ching Chio, Chin-Hung Chang, Jinn-Rung KuoAbstractBackgroundHigh cholesterol has been correlated with a higher risk of cerebrovascular diseases. Whether pre-existing high cholesterol exacerbates traumatic brain injury (TBI), and whether treatment with the cholesterol lowering agent simvastatin has neuroprotective effects, especially anti-neuroinflammtory effects,...
Fri Sep 13, 2019 17:14
Publication date: Available online 10 September 2019Source: World NeurosurgeryAuthor(s): Fusao Ikawa, Nobuaki Michihata, Yasuhiko Akiyama, Koji Iihara, Fumihiro Matano, Akio Morita, Yoko Kato, Koji Iida, Kaoru Kurisu, Kiyohide Fushimi, Hideo YasunagaAbstractBackgroundThis study aimed to clarify the risk factors of treatment for unruptured cerebral aneurysms (UCAs) in elderly patients by comparing the morbidity at discharge between surgical clipping and endovascular coiling in non-elderly (<65...
Fri Sep 13, 2019 17:14
Publication date: Available online 11 September 2019Source: World NeurosurgeryAuthor(s): Giulio Cecchini, Thomas J. Sorenson, Christopher S. Graffeo, Giovanni Vitale, Francesco Di BiaseAbstractIntracranial epidermoid cysts are developmental central nervous system abnormalities that arise from erroneous ectodermal inclusion during neural tube closure. Epidermoids are relatively common representing 1% of all intracranial masses and are particularly predominant in the cerebellopontine angle (CPA), where...
Fri Sep 13, 2019 17:14
Publication date: Available online 11 September 2019Source: World NeurosurgeryAuthor(s): Hao Chen, Jun-Song Yang, Peng Zou, Yuan-Tin Zhao, Tuan-Jiang Liu, Ye Tian, Ke-Yuan Ding, Peng Liu, Jia-Nan Zhang, Ding-Jun HaoObjectiveTo first explore the safety and efficacy of H2O2 in controlling blood loss and SSI after multi-segmental lumbar spine surgery.Methods2626 patients who underwent multi-segmental lumbar spinal surgery between January 2015 and January 2018 were included in this study. According to...
Fri Sep 13, 2019 17:14
Publication date: Available online 11 September 2019Source: World NeurosurgeryAuthor(s): Shkarubo Alexey Nikolaevich, Nikolenko Vladimir Nikolaevich, Chernov Ilia Valerievich, Andreev Dmitry Nikolaevich, Shkarubo Mikhail Alekseevich, Chmutin Kirill Gennadievich, Sinelnikov Mikhail YegorovichAbstract.Interest in endoscopic transnasal access has increased with continued technological advances in endoscopic technology. Objective: The goals of this study were to review the normal anatomy in transnasal...
Fri Sep 13, 2019 17:14
Publication date: Available online 11 September 2019Source: World NeurosurgeryAuthor(s): Seung Hoon Lim, Chang Kyu Park, Bong Jin Park, Young Jin Lim.AbstractObjectiveVestibular schwannomas (VS) can either be solid or contain variable amounts of cystic components. It is established that gamma knife radiosurgery (GKS) was an effective treatment modality for solid VS. However, in case of the cystic VS, Given the somewhat unpredictable growth of the cystic portion of these tumors, microsurgery is often...
Fri Sep 13, 2019 17:14
Publication date: Available online 11 September 2019Source: World NeurosurgeryAuthor(s): Christopher Wu, Ching-Yu Lee, Tsung-Jen Huang, Meng-Huang Wu
Fri Sep 13, 2019 17:14
Publication date: Available online 11 September 2019Source: World NeurosurgeryAuthor(s): Xiao-Dong Zhai, Jia-Xing Yu, Chuan-Jie Li, Jian Ren, Zhe Ji, Chuan He, Ming Ye, Peng Hu, Hong-Qi ZhangAbstractBackgroundCompared with intracranial aneurysms (IAs) at other locations, pericallosal artery aneurysms (PAAs) demonstrate an extremely high risk of rupture. However, due to their rarity, our understanding of their morphological characteristics was limited, and whether the morphological characteristics...
Fri Sep 13, 2019 17:14
Publication date: Available online 11 September 2019Source: World NeurosurgeryAuthor(s): Roberto Rodriguez Rubio, Vera Vigo, Sirin Gandhi, Halima Tabani, Ali Tayebi Meybodi, Ethan A. Winkler, Adib A. Abla, Michael T. Lawton, Arnau BenetAbstractIntroductionDistal ophthalmic artery (OpA) aneurysms are a rare subset of vascular lesions with lack of optimal treatment. The management of these aneurysms may require complete occlusion of the parent vessel, carrying a risk of permanent visual impairment...
Fri Sep 13, 2019 17:14
Publication date: Available online 11 September 2019Source: World NeurosurgeryAuthor(s): V.R. Gupta, C. Giller, R. Kolhe, S.E. Forseen, S. SharmaAbstractBackgroundPolymorphous low-grade neuroepithelial tumor of the young (PLNTY) is a recently recognized epileptogenic neuroepithelial tumor. Despite its distinctiveness, its polymorphous histology and the nature of its oligodendrocyte-like cells remain unclear.Case DescriptionA 30-year-old right-handed male was diagnosed with intractable epilepsy since...
Fri Sep 13, 2019 17:14
Publication date: Available online 11 September 2019Source: World NeurosurgeryAuthor(s): Jianping Song, Peixi Liu, Zhiguang Pan, Kai Quan, Xiaochun Zhao, Wei ZhuAbstractThalamic cavernous malformations (CM) are highly surgically challenging. In this illustrative video, we present a case of a 36-year-old male with a CM located at the left medial thalamus, which was successfully treated via a contralateral anterior interhemispheric transcallosal approach. An informed consent was obtained from the patient....
Fri Sep 13, 2019 17:14
Publication date: Available online 11 September 2019Source: World NeurosurgeryAuthor(s): Sabino Luzzi, Alice Giotta Lucifero, Mattia Del Maestro, Giovanni Marfia, Stefania Elena Navone, Matias Baldoncini, Maximiliano Nuñez, Alvaro Campero, Samer K. Elbabaa, Renato GalzioAbstractBackgroundSchwannomas encompassing the superior parapharyngeal space are challenging lesions because of the anatomical complexity of this region and the frequent involvement of the neurovascular structures of the jugular foramen....
Fri Sep 13, 2019 17:14
Publication date: Available online 11 September 2019Source: World NeurosurgeryAuthor(s): Loren N. Riedy, Miri Kim, Jonathan J. Yun, Ewa Borys, Vikram C. PrabhuAbstractBackgroundMalignant transformation of a mature intracranial teratoma into an adenocarcinoma is an extremely rare event and portends a poor prognosis. The clinical progression, radiographic changes, histopathology, and immunohistochemistry of these unique cases may provide clues as to this transformation. CDX-2 is a specific and robust...
Fri Sep 13, 2019 17:14
Publication date: Available online 11 September 2019Source: World NeurosurgeryAuthor(s): Ran Lador, Gilad Regev, Khalil Salame, Morsi Khashan, Zvi Lidar
Fri Sep 13, 2019 17:14
Publication date: Available online 12 September 2019Source: World NeurosurgeryAuthor(s): Guo Ran, Kaizheng Chen, Yanzhe Huang, Chunbo Hu, Xia ShenAbstractObjectiveTo evaluate whether use of partial nondepolarizing neuromuscular blocking agents (NMBAs), at a train of four (TOF) level 1, compromise the facial nerve monitoring during vestibular schwanoma (VS) resection.MethodsSixty consecutive patients undergoing vestibular schwanoma resection were enrolled into partial peripheral neuromuscular blockade...
Fri Sep 13, 2019 17:14
Publication date: Available online 12 September 2019Source: World NeurosurgeryAuthor(s): Kaiyu Liu, Hengrui Chang, Lifei Wang, Chunlei Wang, Tao Chen, Xianzhong MengAbstractPurposeAlthough many risk factors for cage retropulsion (CR) following lumbar interbody fusion (LIF) have been described in the literature, they still remain controversial. The purpose of this study is to investigate the risk factors for CR after LIF.MethodsThe literature was searched in Pubmed, Cochrane library and Embase from...
Fri Sep 13, 2019 17:14
Publication date: Available online 12 September 2019Source: World NeurosurgeryAuthor(s): Fusao Ikawa, Nobuaki Michihata, Koji Iihara, Yasuhiko Akiyama, Akio Morita, Kiyohide Fushimi, Hideo Yasunaga, Kaoru KurisuAbstractObjectiveThere has been no precise guide for treatment management of aneurysmal subarachnoid hemorrhage (aSAH) based on the patient’s age and treatment method. This study clarifies each risk management for aSAH according to age and treatment method listed in a nationwide database.MethodsWe...
Fri Sep 13, 2019 17:14
Publication date: Available online 12 September 2019Source: World NeurosurgeryAuthor(s): Alaa S. Montaser, Daniel M. Prevedello, Matias Gomez, Lucas Lima, André Beer-Furlan, Diego Servian, Bradley A. Otto, Ricardo L. CarrauAbstract:BackgroundIntracranial aneurysms located in the midline region represent formidable challenge owing to their deep location.ObjectiveThe purpose of this study is to assess feasibility and identify the limitations of endoscopic endonasal clipping of intracranial aneurysms....
Fri Sep 13, 2019 17:14
Publication date: Available online 12 September 2019Source: World NeurosurgeryAuthor(s): Daina Kashiwazaki, Hisayasu Saito, Haruto Uchino, Naoki Akioka, Emiko Hori, Takashi Shibata, Takahiro Tomita, Takuya Akai, Naoya Kuwayama, Satoshi Kuroda
Fri Sep 13, 2019 17:14
Publication date: Available online 12 September 2019Source: World NeurosurgeryAuthor(s): Carlo Bortolotti, Giacomo Bertolini, Thomas J. Sorenson, Luigi Cirillo, Giuseppe Lanzino, Carmelo Sturiale
Fri Sep 13, 2019 17:14
Publication date: Available online 12 September 2019Source: World NeurosurgeryAuthor(s): Shiying Gai, Nan Lv, Qi Zhang, Qiao Zuo, Jianmin Liu, Qinghai HuangAbstractObjectiveWe present a case of multiple myxoma-related intracranial aneurysms and review the recent relevant literatures to investigate their natural course and reasonable treatment algorithm.MethodA new case of multiple myxoma-related intracranial aneurysms was reported and a search of current literature in PubMed was performed. Keywords...
Fri Sep 13, 2019 17:14
Publication date: Available online 12 September 2019Source: World NeurosurgeryAuthor(s): Aditya V. Karhade, Paul T. Ogink, Quirina C.B.S. Thio, Thomas D. Cha, Stuart H. Hershman, Andrew J. Schoenfeld, Christopher M. Bono, Joseph H. SchwabAbstract:ObjectiveAge and comorbidity burden of anterior cervical discectomy and fusion (ACDF) patients have increased significantly over the past two decades, resulting in increased expenditures. Non-home discharge after ACDF contributes to increased direct and...
Fri Sep 13, 2019 17:14
Publication date: Available online 12 September 2019Source: World NeurosurgeryAuthor(s): Herschel Wilde, Austin S. Gamblin, Jared Reese, Jason G. Garry, Jian Guan, Janel Mortenson, Alexandra Flis, Jeffrey P. Rosenbluth, Michael Karsy, Erica F. Bisson, Andrew T. DaileyAbstractObjectiveSpine fractures, including associated spinal cord injury, account for 3–6% of all skeletal fractures annually in the U.S.. Patients who undergo interhospital transfer after injury may have a greater likelihood of nonroutine...
Fri Sep 13, 2019 17:14
Publication date: Available online 12 September 2019Source: World NeurosurgeryAuthor(s): Li-Min Zhang, Rui Li, Wen-Bo Sun, Xu-Peng Wang, Man-Man Qi, Yang Bai, Jing Bai, Weichao ZhengAbstractBackgroundTo investigate the role of Low-dose, Early Fresh frozen plasma Transfusion (LEFT) therapy in preventing peri-operative coagulopathy and improving long-term outcome after severe traumatic brain injury (TBI).MethodsA prospected, single-centre, parallel-group, randomized trial was designed. Patients with...
Fri Sep 13, 2019 17:14
Publication date: Available online 12 September 2019Source: World NeurosurgeryAuthor(s): Sunil Munakomi, Aliza Bajracharya
Fri Sep 13, 2019 17:14
Publication date: Available online 12 September 2019Source: World NeurosurgeryAuthor(s): Juan F. Villalonga, Tomas Ries Centeno, Amparo Sáenz, Domenico Solari, Andrés Cervio, Alvaro CamperoAbstractBackgroundThe use of the recent concept of sellar barrier revealed that a specific group of patients were difficult to categorize. For this reason, we propose to add a new subtype: The mixed sellar barrier. The aim of this work is to define the new mixed barrier subtype and analyze this in a series of operated...
Fri Sep 13, 2019 17:14
Management of extracranial blunt cerebrovascular injuries: experience with an aspirin-based approach
Publication date: Available online 12 September 2019Source: World NeurosurgeryAuthor(s): Joshua S. Catapano, Sharjeel Israr, Alexander C. Whiting, Omar M. Hussain, Laura A. Snyder, Felipe C. Albuquerque, Andrew F. Ducruet, Peter Nakaji, Michael T. Lawton, Jordan A. Weinberg, Joseph M. ZabramskiAbstractBackgroundOptimal management of patients with extracranial blunt cerebrovascular injury (BCVI) remains controversial, with both anticoagulation and antiplatelet therapy being recommended. The purpose...
Fri Sep 13, 2019 17:14
Publication date: Available online 13 September 2019Source: World NeurosurgeryAuthor(s): Sam Supreeth, Khalifa A. Al Ghafri, Renjit Kumar J, Zakariya Y. Al BalushiAbstractWe report a very rare case of Spondylodiscitis with epidural collection due to Candida Auris which has a lowest incidence in spine. Candida Auris was confirmed by VITEK-2 and MALDI-TOF on the biopsy sample. Patient underwent instrumented posterior lumbar fusion with bone graft followed by antifungal Caspofungin for a duration of...
Fri Sep 13, 2019 17:14
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