Nutrients, Vol. 11, Pages 2046: A Longitudinal Assessment of Diet Quality and Risks Associated with Malnutrition in Socioeconomic and Racially Diverse Adults Nutrients doi: 10.3390/nu11092046 Authors: Marie Fanelli Kuczmarski Emily Stave Shupe Ryan T. Pohlig Rita Rawal Alan B. Zonderman Michele K. Evans Little is known about the effects of diet quality through adulthood and its association with malnutrition later in life. The first research objective was to evaluate diet...
Nutrients, Vol. 11, Pages 2052: Inflammatory Dietary Pattern Predicts Dyslipidemia and Anemia in Middle-Aged and Older Taiwanese Adults with Declined Kidney Function: A Cross-Sectional Population Study from 2008 to 2010 Nutrients doi: 10.3390/nu11092052 Authors: Adi Lukas Kurniawan Chien-Yeh Hsu Hsiao-Hsien Rau Li-Yin Lin Jane C-J Chao Dyslipidemia, anemia, and inflammation are associated with declined kidney function. This study investigated the association of inflammatory...
Nutrients, Vol. 11, Pages 2053: Does an Age-Specific Treatment Program Augment the Efficacy of a Cognitive-Behavioral Weight Loss Program in Adolescence and Young Adulthood? Results from a Controlled Study Nutrients doi: 10.3390/nu11092053 Authors: Petra Warschburger Jana Zitzmann Research on weight-loss interventions in emerging adulthood is warranted. Therefore, a cognitive-behavioral group treatment (CBT), including development-specific topics for adolescents and young adults with...
Nutrients, Vol. 11, Pages 2048: Probiotics in Irritable Bowel Syndrome: An Up-to-Date Systematic Review Nutrients doi: 10.3390/nu11092048 Authors: Hanna Fjeldheim Dale Stella Hellgren Rasmussen Özgün Ömer Asiller Gülen Arslan Lied Irritable bowel syndrome (IBS) is a frequent functional gastrointestinal disorder, and alterations in the gut microbiota composition contributes to symptom generation. The exact mechanisms of probiotics in the human body are not fully understood, but...
Nutrients, Vol. 11, Pages 2049: Sparassis crispa Intake Improves the Reduced Lipopolysaccharide-Induced TNF-α Production That Occurs upon Exhaustive Exercise in Mice Nutrients doi: 10.3390/nu11092049 Authors: Masataka Uchida Naoki Horii Natsuki Hasegawa Eri Oyanagi Hiromi Yano Motoyuki Iemitsu Our previous study showed that lipopolysaccharide (LPS)-induced tumor necrosis factor (TNF)-α production is inhibited by acute exhaustive exercise in mice, leading to transient...
Nutrients, Vol. 11, Pages 2050: Taste Perception of Nutrients Found in Nutritional Supplements: A Review Nutrients doi: 10.3390/nu11092050 Authors: Thomas Delompré Elisabeth Guichard Loïc Briand Christian Salles Nutritional supplements are prescribed when one’s nutritional status is not conducive to good health. These foodstuffs constitute concentrated sources of nutrients such as vitamins, minerals, amino acids, and fatty acids. For nutritional supplements to be effective,...
Nutrients, Vol. 11, Pages 2047: Comparative Meta-Analysis of the Effect of Concentrated, Hydrolyzed, and Isolated Whey Protein Supplementation on Body Composition of Physical Activity Practitioners Nutrients doi: 10.3390/nu11092047 Authors: Luis Henrique A. Castro Flávio Henrique S. de Araújo Mi Ye M. Olimpio Raquel B. de B. Primo Thiago T. Pereira Luiz Augusto F. Lopes Erasmo B. S. de M. Trindade Ricardo Fernandes Silvia A. Oesterreich Whey protein (WP) is a...
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Pharmaceuticals, Vol. 12, Pages 129: The Antitumor Didox Acts as an Iron Chelator in Hepatocellular Carcinoma Cells Pharmaceuticals doi: 10.3390/ph12030129 Authors: Michela Asperti Luca Cantamessa Simone Ghidinelli Magdalena Gryzik Andrea Denardo Arianna Giacomini Giovanna Longhi Alessandro Fanzani Paolo Arosio Maura Poli Ribonucleotide reductase (RR) is the rate-limiting enzyme that controls the deoxynucleotide triphosphate synthesis and it is an important...
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Pharmaceutics, Vol. 11, Pages 453: Effectiveness of a Pharmacogenetic Tool at Improving Treatment Efficacy in Major Depressive Disorder: A Meta-Analysis of Three Clinical Studies Pharmaceutics doi: 10.3390/pharmaceutics11090453 Authors: Vilches Tuson Vieta Álvarez Espadaler Several pharmacogenetic tests to support drug selection in psychiatric patients have recently become available. The current meta-analysis aimed to assess the clinical utility of a commercial pharmacogenetic-based...
Pharmaceutics, Vol. 11, Pages 452: Understanding and Kinetic Modeling of Complex Degradation Pathways in the Solid Dosage Form: The Case of Saxagliptin Pharmaceutics doi: 10.3390/pharmaceutics11090452 Authors: Robnik Likozar Wang Stanić Ljubin Časar Drug substance degradation kinetics in solid dosage forms is rarely mechanistically modeled due to several potential micro-environmental and manufacturing related effects that need to be integrated into rate laws. The aim...
Pharmaceutics, Vol. 11, Pages 451: Microencapsulation Curcuminoids for Effective Delivery in Pharmaceutical Application Pharmaceutics doi: 10.3390/pharmaceutics11090451 Authors: Ang Darwis Por Yam Curcuminoids have been long proven to possess antioxidant, anti-inflammatory and antibacterial properties which are crucial in their role as a pharmacological active agent. However, its poor solubility, high oxidative degradation, light sensitivity and poor bioavailability have...
Pharmaceutics, Vol. 11, Pages 454: Systematic Meta-Analysis Identifies Co-Expressed Kinases and GPCRs in Ovarian Cancer Tissues Revealing a Potential for Targeted Kinase Inhibitor Delivery Pharmaceutics doi: 10.3390/pharmaceutics11090454 Authors: Albrecht Kübler The use of many anticancer drugs is problematic due to severe adverse effects. While the recent clinical launch of several kinase inhibitors led to tremendous progress, these targeted agents tend to be of non-specific nature...
Pharmaceutics, Vol. 11, Pages 450: Combination of Proton Therapy and Radionuclide Therapy in Mice: Preclinical Pilot Study at the Paul Scherrer Institute Pharmaceutics doi: 10.3390/pharmaceutics11090450 Authors: Cristina Müller Maria De Prado Leal Marco D. Dominietto Christoph A. Umbricht Sairos Safai Rosalind L. Perrin Martina Egloff Peter Bernhardt Nicholas P. van der Meulen Damien C. Weber Roger Schibli Antony J. Lomax Proton therapy (PT) is a treatment...
Pharmaceutics, Vol. 11, Pages 449: Preparation of Lutein-Loaded PVA/Sodium Alginate Nanofibers and Investigation of Its Release Behavior Pharmaceutics doi: 10.3390/pharmaceutics11090449 Authors: Xinxu Han Peipei Huo Zhongfeng Ding Parveen Kumar Bo Liu This investigation aims to study the characteristics and release properties of lutein-loaded polyvinyl alcohol/sodium alginate (PVA/SA) nanofibers prepared by electrospinning. In order to increase PVA/SA nanofibers’...
Pharmaceutics, Vol. 11, Pages 446: Computational Drug Repurposing Algorithm Targeting TRPA1 Calcium Channel as a Potential Therapeutic Solution for Multiple Sclerosis Pharmaceutics doi: 10.3390/pharmaceutics11090446 Authors: Dragos Paul Mihai George Mihai Nitulescu George Nicolae Daniel Ion Cosmin Ionut Ciotu Cornel Chirita Simona Negres Multiple sclerosis (MS) is a chronic autoimmune disease affecting the central nervous system (CNS) through neurodegeneration and demyelination,...
Pharmaceutics, Vol. 11, Pages 448: Nanosystems as Vehicles for the Delivery of Antimicrobial Peptides (AMPs) Pharmaceutics doi: 10.3390/pharmaceutics11090448 Authors: Ángela Martin-Serrano Rafael Gómez Paula Ortega F. Javier de la Mata Recently, antimicrobial peptides (AMPs), also called host defence peptides (HDPs), are attracting great interest, as they are a highly viable alternative in the search of new approaches to the resistance presented by bacteria against antibiotics...
Pharmaceutics, Vol. 11, Pages 447: Film Dressings Based on Hydrogels: Simultaneous and Sustained-Release of Bioactive Compounds with Wound Healing Properties Pharmaceutics doi: 10.3390/pharmaceutics11090447 Authors: Fabian Ávila-Salas Adolfo Marican Soledad Pinochet Gustavo Carreño Oscar Valdés Bernardo Venegas Wendy Donoso Gustavo Cabrera-Barjas Sekar Vijayakumar Esteban F. Durán-Lara This research proposes the rational modeling, synthesis and evaluation of...
Pharmaceutics, Vol. 11, Pages 445: Skin-on-a-Chip Device for Ex Vivo Monitoring of Transdermal Delivery of Drugs—Design, Fabrication, and Testing Pharmaceutics doi: 10.3390/pharmaceutics11090445 Authors: Bence Lukács Ágnes Bajza Dorottya Kocsis Attila Csorba István Antal Kristóf Iván András József Laki Franciska Erdő To develop proper drug formulations and to optimize the delivery of their active ingredients through the dermal barrier, the Franz diffusion cell system...
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Pharmacy, Vol. 7, Pages 129: Deprescribing: Practical Ways to Support Person-Centred, Evidence-Based Deprescribing Pharmacy doi: 10.3390/pharmacy7030129 Authors: Katherine Le Bosquet Nina Barnett John Minshull Deprescribing is complex and multifactorial with multiple approaches described in the literature. Internationally, there are guidelines and tools available to aid clinicians and patients to identify and safely withdraw inappropriate medications, post a shared decision-making...
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Plants, Vol. 8, Pages 321: Proteome Profiling of the Mutagen-Induced Morphological and Yield Macro-Mutant Lines of Nigella sativa L. Plants doi: 10.3390/plants8090321 Authors: Ambreen Asif Mohammad Yunus K. Ansari Abeer Hashem Baby Tabassum Elsayed Fathi Abd_Allah Altaf Ahmad In the present investigation, the leaf proteome profile of the macro-mutant lines of Nigella sativa L. was analyzed to identify the key proteins involved in the expression of traits associated with...
Plants, Vol. 8, Pages 320: Decrease in Bat Diversity Points towards a Potential Threshold Density for Black Cherry Management: A Case Study from Germany Plants doi: 10.3390/plants8090320 Authors: Jonas Geschke In times of land use changes towards more close-to-nature forestry, the application of bioindicators becomes an interesting tool for effective land-use management schemes. Forest managers are increasingly confronted by alien tree species. Therefore, this case study aimed to investigate...
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Religions, Vol. 10, Pages 510: Past as Prophecy: Indigenous Diplomacies beyond Liberal Settler Regimes of Recognition, as Told in Shell Religions doi: 10.3390/rel10090510 Authors: Lee Bloch According to a prophecy told in a small, Muskogee-identified community in the US South, the seeds of Indigenous ways of knowing and relating to more-than-human kin will once again flourish in the ruins of colonial orders. Even settlers will be forced to turn to Indigenous knowledges because “they...
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Sci. Pharm., Vol. 87, Pages 22: Anti-Inflammatory and Antioxidant Activities of Medicinal Plants Used by Traditional Healers for Antiulcer Treatment Scientia Pharmaceutica doi: 10.3390/scipharm87030022 Authors: Kanokkarn Phromnoi Puksiri Sinchaiyakij Chakkrit Khanaree Piyawan Nuntaboon Yupa Chanwikrai Thida Chaiwangsri Maitree Suttajit For centuries, many kinds of native plants and their products have been used for the treatment of gastric ulcers by traditional healers...
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Social Sciences, Vol. 8, Pages 251: Trust and Distrust: Listening to Children about Their Relationships with Professionals Social Sciences doi: 10.3390/socsci8090251 Authors: Hayley Davies This article explores trust in children’s relationships with professionals in the context of safeguarding concerns. With exception, existing research with children about trust in professionals often fails to unpick trust. Using sociological conceptualisations of trust, most often considered...
Social Sciences, Vol. 8, Pages 250: Parents’ Strategies in Dealing with Constructions of Gendered Responsibilities at Their Workplaces Social Sciences doi: 10.3390/socsci8090250 Authors: Gerlinde Mauerer Eva-Maria Schmidt This paper, which is based on qualitative research conducted in Austria, focuses on current gender inequalities between parents in fulfilling their parental responsibilities, which means reconciling the responsibilities of childcare and earning a living. Austria...
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Sports, Vol. 7, Pages 203: Multiple Fitness Improvements Found after 6-Months of High Intensity Functional Training Sports doi: 10.3390/sports7090203 Authors: Sarah J. Cosgrove Derek A. Crawford Katie M. Heinrich While short-term high intensity functional training (HIFT) effects have been established, fitness improvements from program participation exceeding 16 weeks are unknown. This study examined the effectiveness of participation in HIFT through CrossFit. During 2013–2014,...
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Toxins, Vol. 11, Pages 512: Production of β-methylamino-L-alanine (BMAA) and Its Isomers by Freshwater Diatoms Toxins doi: 10.3390/toxins11090512 Authors: Jake P. Violi Jordan A. Facey Simon M. Mitrovic Anne Colville Kenneth J. Rodgers β-methylamino-L-alanine (BMAA) is a non-protein amino acid that has been implicated as a risk factor for motor neurone disease (MND). BMAA is produced by a wide range of cyanobacteria globally and by a small number of marine diatoms....
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TropicalMed, Vol. 4, Pages 117: Geographical Distribution of β-Lactam Resistance among Klebsiella spp. from Selected Health Facilities in Ghana Tropical Medicine and Infectious Disease doi: 10.3390/tropicalmed4030117 Authors: Elvis Quansah Prince Amoah Barnie Desmond Omane Acheampong Dorcas Obiri-Yeboah Richael Odarkor Mills Ebenezer Asmah Obed Cudjoe Isaac Dadzie β-Lactam-resistant Klebsiella isolates continue to cause multidrug resistance infections worldwide....
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Vaccines, Vol. 7, Pages 105: Peptide-Based Vaccination for Antibody Responses Against HIV Vaccines doi: 10.3390/vaccines7030105 Authors: Combadière Beaujean Chaudesaigues Vieillard HIV-1 is responsible for a global pandemic of 35 million people and continues to spread at a rate of >2 million new infections/year. It is widely acknowledged that a protective vaccine would be the most effective means to reduce HIV-1 spread and ultimately eliminate the pandemic, whereas...
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Viruses, Vol. 11, Pages 814: Evolutionary Dynamics of the Lineage 2 West Nile Virus That Caused the Largest European Epidemic: Italy 2011–2018 Viruses doi: 10.3390/v11090814 Authors: Carla Veo Carla della Ventura Ana Moreno Francesca Rovida Elena Percivalle Sabrina Canziani Debora Torri Mattia Calzolari Fausto Baldanti Massimo Galli Gianguglielmo Zehender Lineage 2 West Nile virus (WNV) caused a vast epidemic in Europe in 2018, with the highest incidence...
Viruses, Vol. 11, Pages 813: Strain-Dependent Porcine Circovirus Type 2 (PCV2) Entry and Replication in T-Lymphoblasts Viruses doi: 10.3390/v11090813 Authors: Wei Van Renne Nauwynck Porcine circovirus type 2 (PCV2) is the etiological agent of PCV2-associated diseases (PCVAD). PCV2 targets lymphoblasts, and pigs suffering from PCVAD display lymphocyte depletion in lymphoid tissues. PCV2 infection of lymphoblasts has not been studied. Here, the replication cycle of PCV2 (abortion...
Viruses, Vol. 11, Pages 812: Virus Shedding of Avian Influenza in Poultry: A Systematic Review and Meta-Analysis Viruses doi: 10.3390/v11090812 Authors: Germeraad Sanders Hagenaars Jong Beerens Gonzales Understanding virus shedding patterns of avian influenza virus (AIV) in poultry is important for understanding host-pathogen interactions and developing effective control strategies. Many AIV strains were studied in challenge experiments in poultry, but no study has...
Viruses, Vol. 11, Pages 811: Long-Acting HIV-1 Fusion Inhibitory Peptides and their Mechanisms of Action Viruses doi: 10.3390/v11090811 Authors: Chen Wang Shuihong Cheng Yuanyuan Zhang Yibo Ding Huihui Chong Hui Xing Shibo Jiang Xuebing Li Liying Ma The clinical application of HIV fusion inhibitor, enfuvirtide (T20), was limited mainly because of its short half-life. Here we designed and synthesized two PEGylated C34 peptides, PEG2kC34 and PEG5kC34, with the PEG...
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Vision, Vol. 3, Pages 44: Spatial Frequency Tuning and Transfer of Perceptual Learning for Motion Coherence Reflects the Tuning Properties of Global Motion Processing Vision doi: 10.3390/vision3030044 Authors: Jordi Asher Vincenzo Romei Paul Hibbard Perceptual learning is typically highly specific to the stimuli and task used during training. However, recently, it has been shown that training on global motion can transfer to untrained tasks, reflecting the generalising properties...
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Water, Vol. 11, Pages 1827: Effects of Climate Change and Flow Regulation on the Flow Characteristics of a Low-Relief River within Southern Boreal Climate Area Water doi: 10.3390/w11091827 Authors: Kasvi Lotsari Kumpumäki Dubrovin Veijalainen We investigated how hydro-climatological changes would affect fluvial forces and inundated area during a typical high-flow situation (MHQ, mean high discharge), and how adaptive regulation could attenuate the climate change impacts...
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