Nutrients, Vol. 11, Pages 2209: Dietary Patterns and Cardiometabolic Outcomes in Diabetes: A Summary of Systematic Reviews and Meta-Analyses Nutrients doi: 10.3390/nu11092209 Authors: Hana Kahleova Jordi Salas-Salvadó Dario Rahelić Cyril WC Kendall Emilie Rembert John L Sievenpiper The Diabetes and Nutrition Study Group (DNSG) of the European Association for the Study of Diabetes (EASD) conducted a review of existing systematic reviews and meta-analyses to explain the...
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Particles, Vol. 2, Pages 411-443: Meson Condensation Particles doi: 10.3390/particles2030025 Authors: Massimo Mannarelli We give a pedagogical review of the properties of the various meson condensation phases triggered by a large isospin or strangeness imbalance. We argue that these phases are extremely interesting and powerful playground for exploring the properties of hadronic matter. The reason is that they are realized in a regime in which various theoretical methods overlap with...
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Pharmaceuticals, Vol. 12, Pages 134: Special Issue “Anticancer Drugs” Pharmaceuticals doi: 10.3390/ph12030134 Authors: Mary J. Meegan Niamh M. O’Boyle The focus of this Special Issue of Pharmaceuticals is on the design, synthesis, and molecular mechanism of action of novel antitumor, drugs with a special emphasis on the relationship between the chemical structure and the biological activity of the molecules. This Special Issue also provides an understanding of the biologic and genotypic...
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Pharmaceutics, Vol. 11, Pages 478: Therapeutic Effects in a Transient Middle Cerebral Artery Occlusion Rat Model by Nose-To-Brain Delivery of Anti-TNF-Alpha siRNA with Cell-Penetrating Peptide-Modified Polymer Micelles Pharmaceutics doi: 10.3390/pharmaceutics11090478 Authors: Takanori Kanazawa Takumi Kurano Hisako Ibaraki Yuuki Takashima Toyofumi Suzuki Yasuo Seta We previously reported that siRNA delivery to the brain is improved by the nose-to-brain delivery route and...
Pharmaceutics, Vol. 11, Pages 477: Magnetoliposomes Containing Calcium Ferrite Nanoparticles for Applications in Breast Cancer Therapy Pharmaceutics doi: 10.3390/pharmaceutics11090477 Authors: Pereira Cardoso Rodrigues Amorim Amaral Almeida Queiroz Martinho Baltazar Calhelha Ferreira Coutinho Castanheira Magnetoliposomes containing calcium ferrite (CaFe2O4) nanoparticles were developed and characterized for the first time. CaFe2O4 nanoparticles...
Pharmaceutics, Vol. 11, Pages 476: Ex Vivo Conjunctival Retention and Transconjunctival Transport of Poorly Soluble Drugs Using Polymeric Micelles Pharmaceutics doi: 10.3390/pharmaceutics11090476 Authors: Pescina Lucca Govoni Padula Favero Cantù Santi Nicoli This paper addresses the problem of ocular delivery of lipophilic drugs. The aim of the paper is the evaluation of polymeric micelles, prepared using TPGS (d-α-Tocopheryl polyethylene glycol...
Pharmaceutics, Vol. 11, Pages 475: Microencapsulation of Enteric Bacteriophages in a pH-Responsive Solid Oral Dosage Formulation Using a Scalable Membrane Emulsification Process Pharmaceutics doi: 10.3390/pharmaceutics11090475 Authors: Vinner Richards Leppanen Sagona Malik A scalable low-shear membrane emulsification process was used to produce microencapsulated Escherichia coli-phages in a solid oral dosage form. Uniform pH-responsive composite microparticles (mean...
Pharmaceutics, Vol. 11, Pages 473: A Role for Nanoparticles in Treating Traumatic Brain Injury Pharmaceutics doi: 10.3390/pharmaceutics11090473 Authors: Badrul Alam Bony Forrest M. Kievit Traumatic brain injury (TBI) is one of the main causes of disability in children and young adults, as well as a significant concern for elderly individuals. Depending on the severity, TBI can have a long-term impact on the quality of life for survivors of all ages. The primary brain injury can result...
Pharmaceutics, Vol. 11, Pages 474: A Novel Framework to Aid the Development of Design Space across Multi-Unit Operation Pharmaceutical Processes—A Case Study of Panax Notoginseng Saponins Immediate Release Tablet Pharmaceutics doi: 10.3390/pharmaceutics11090474 Authors: Fei Sun Bing Xu Shengyun Dai Yi Zhang Zhaozhou Lin Yanjiang Qiao The fundamental principle of Quality by Design (QbD) is that the product quality should be designed into the process through an upstream...
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Plants, Vol. 8, Pages 350: Antimicrobial Activity, Antioxidant Potential, Cytotoxicity and Phytochemical Profiling of Four Plants Locally Used against Skin Diseases Plants doi: 10.3390/plants8090350 Authors: John A. Asong Stephen O. Amoo Lyndy J. McGaw Sanah M. Nkadimeng Adeyemi O. Aremu Wilfred Otang-Mbeng Although orthodox medications are available for skin diseases, expensive dermatological services have necessitated the use of medicinal plants as a cheaper alternative....
Plants, Vol. 8, Pages 349: Selection of Parental Material to Maximize Heterosis Using SNP and SilicoDarT Markers in Maize Plants doi: 10.3390/plants8090349 Authors: Agnieszka Tomkowiak Jan Bocianowski Dominika Radzikowska Przemysław Łukasz Kowalczewski The chief aim of plant breeding is to improve varieties so as to increase their yield and breeding traits. One of the first stages of breeding is the selection of parental forms from the available gene pool of existing varieties....
Plants, Vol. 8, Pages 348: Understanding the Role of the Antioxidant System and the Tetrapyrrole Cycle in Iron Deficiency Chlorosis Plants doi: 10.3390/plants8090348 Authors: Carla S. Santos Rengin Ozgur Baris Uzilday Ismail Turkan Mariana Roriz António O.S.S. Rangel Susana M.P. Carvalho Marta W. Vasconcelos Iron deficiency chlorosis (IDC) is an abiotic stress often experienced by soybean, owing to the low solubility of iron in alkaline soils. Here, soybean lines...
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Psych, Vol. 1, Pages 469-481: The EmojiGrid as a Tool to Assess Experienced and Perceived Emotions Psych doi: 10.3390/psych1010036 Authors: Toet van Erp In a recent study on food-evoked emotions, we observed that people often misunderstood the currently available affective self-report tools. We, therefore, developed a new intuitive and language-independent self-report instrument called the EmojiGrid: a rectangular response grid labeled with facial icons (emoji) that express different...
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Religions, Vol. 10, Pages 529: Being Christian through External Giving Religions doi: 10.3390/rel10090529 Authors: Steve Wai Lung Cheung Khun Eng Kuah This study examines how Christian informants understand and practice external (charitable) giving outside of their church, both in terms of money and volunteering time and effort. While existing quantitative researches have informed us primarily about the determinants of giving in the West, we carry out a small case study in a church...
Religions, Vol. 10, Pages 528: Payback, Forgiveness, Accountability: Exercising Responsible Agency in the Midst of Structured Racial Harm Religions doi: 10.3390/rel10090528 Authors: Michael P. Jaycox In a context of political conflict, the practice of vengeance, the paying back of harm in exchange for harm suffered, is obviously an ethical problem. The practice of forgiveness is equally though differently problematic when applied to political conflict despite the fact that it is a moral...
Religions, Vol. 10, Pages 527: Religiosity, Religious Practice, and Antisemitism in Present-Day Hungary Religions doi: 10.3390/rel10090527 Authors: Ildikó Barna András Kovács Since 1995, Surveys on antisemitism using national representative samples have been regularly carried out in Hungary. In this article, we used data from the 2011 and 2017 surveys to explore the relationship between three types of antisemitism, namely religious, secular, and emotional. Moreover, we scrutinized...
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Robotics, Vol. 8, Pages 81: Virtualization of Robotic Hands Using Mobile Devices Robotics doi: 10.3390/robotics8030081 Authors: Santiago T. Puente Lucía Más Fernando Torres and Francisco A. Candelas This article presents a multiplatform application for the tele-operation of a robot hand using virtualization in Unity 3D. This approach grants usability to users that need to control a robotic hand, allowing supervision in a collaborative way. This paper focuses on a user application...
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Sci, Vol. 1, Pages 53: Organic Molecules: Is It Possible to Distinguish Aromatics from Aliphatics Collected by Space Missions in High Speed Impacts? Sci doi: 10.3390/sci1020053 Authors: Mark Burchell Kathryn Harriss A prime site of astrobiological interest within the Solar System is the interior ocean of Enceladus. This ocean has already been shown to contain organic molecules and is thought to have the conditions necessary for more complex organic biomolecules to emerge and potentially...
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Social Sciences, Vol. 8, Pages 262: Integrating Social Scientific Perspectives on the Quantified Employee Self Social Sciences doi: 10.3390/socsci8090262 Authors: Thomas Calvard A key technological trend in big data science is that of the quantified self, whereby individuals can self-track their health and well-being using various sources of information. The aim of this article was to integrate multidimensional views on the positive and negative implications of the quantified self for...
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Societies, Vol. 9, Pages 65: Gaining Legitimacy in Post-Qaddafi Libya: Analysing Attempts of the Muslim Brotherhood Societies doi: 10.3390/soc9030065 Authors: Inga Kristina Trauthig The Libyan Muslim Brotherhood needed to manoeuvre underground for several decades, just as most opposition groups in Libya had to—because of the repression from the Qaddafi regime. In 2012, however, the political wing of the Libyan Muslim Brotherhood (LMB), the Justice and Construction Party (JCP,...
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Sports, Vol. 7, Pages 212: Identifying Unique Contributions of the Coach–Athlete Working Alliance, Psychological Resilience and Perceived Stress on Athlete Burnout among Norwegian Junior Athletes Sports doi: 10.3390/sports7090212 Authors: Emilie F. W. Raanes Maria Hrozanova Frode Moen The main purpose of the current study was to examine how the coach-athlete working alliance, psychological resilience and perceived stress are uniquely associated with burnout among junior athletes...
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Technologies, Vol. 7, Pages 67: Evaluation of Wirelessly Transmitted Video Quality Using a Modular Fuzzy Logic System Technologies doi: 10.3390/technologies7030067 Authors: Salama Saatchi Video transmission over wireless computer networks is increasingly popular as new applications emerge and wireless networks become more widespread and reliable. An ability to quantify the quality of a video transmitted using a wireless computer network is important for determining network performance...
Technologies, Vol. 7, Pages 66: A Bayesian Study of the Dynamic Effect of Comorbidities on Hospital Outcomes of Care for Congestive Heart Failure Patients Technologies doi: 10.3390/technologies7030066 Authors: Dimitrios Zikos Stelios Zimeras Neli Ragina Comorbidities can have a cumulative effect on hospital outcomes of care, such as the length of stay (LOS), and hospital mortality. This study examines patients hospitalized with congestive heart failure (CHF), a life-threatening...
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Toxins, Vol. 11, Pages 538: The Cadherin Cry1Ac Binding-Region is Necessary for the Cooperative Effect with ABCC2 Transporter Enhancing Insecticidal Activity of Bacillus thuringiensis Cry1Ac Toxin Toxins doi: 10.3390/toxins11090538 Authors: Ma Zhang Xiao Yang Liu Peng Yang Bravo Soberón Liu Bacillus thuringiensis Cry1Ac toxin binds to midgut proteins, as cadherin (CAD) and ABCC2 transporter, to form pores leading to larval death. In cell lines, co-expression...
Toxins, Vol. 11, Pages 537: Twenty-Eight Fungal Secondary Metabolites Detected in Pig Feed Samples: Their Occurrence, Relevance and Cytotoxic Effects In Vitro Toxins doi: 10.3390/toxins11090537 Authors: Barbara Novak Valentina Rainer Michael Sulyok Dietmar Haltrich Gerd Schatzmayr Elisabeth Mayer Feed samples are frequently contaminated by a wide range of chemically diverse natural products, which can be determined using highly sensitive analytical techniques. Next to...
Toxins, Vol. 11, Pages 535: Molecular Characterization of Equine Staphylococcus aureus Isolates Exhibiting Reduced Oxacillin Susceptibility Toxins doi: 10.3390/toxins11090535 Authors: Scholtzek Hanke Walther Eichhorn Stöckle Klein Gehlen Lübke-Becker Schwarz Feßler The detection of borderline oxacillin-resistant Staphylococcus aureus (BORSA) represents a challenge to both, veterinary and human laboratories. Between 2015 and 2017, 19 equine S. aureus...
Toxins, Vol. 11, Pages 536: The Effect of Blue Light on the Production of Citrinin in Monascus purpureus M9 by Regulating the mraox Gene through lncRNA AOANCR Toxins doi: 10.3390/toxins11090536 Authors: Yang Wang Li Guo Yang Chen Wang Blue light, as an important environmental factor, can regulate the production of various secondary metabolites of Monascus purpureus M9, including mycotoxin-citrinin, pigments, and monacolin K. The analysis of citrinin in Monascus...
Toxins, Vol. 11, Pages 534: Impact of the Lipopolysaccharide Chemotype of Salmonella Enterica Serovar Typhimurium on Virulence in Gnotobiotic Piglets Toxins doi: 10.3390/toxins11090534 Authors: Alla Splichalova Zdislava Splichalova Daniela Karasova Ivan Rychlik Paolo Trevisi Marek Sinkora Igor Splichal Salmonella Typhimurium is an enteric pathogen that causes acute and chronic infections in humans and animals. One-week-old germ-free piglets were orally colonized/infected...
Toxins, Vol. 11, Pages 533: Rationally Designed Synthetic Haptens to Generate Anti-Ciguatoxin Monoclonal Antibodies, and Development of a Practical Sandwich ELISA to Detect Ciguatoxins Toxins doi: 10.3390/toxins11090533 Authors: Takeshi Tsumuraya Masahiro Hirama “Ciguatera” fish poisoning (CFP) is one of the well-known food poisoning caused by the ingestion of fish that have accumulated trace amounts of ciguatoxins (CTXs). CFP affects more than 50,000 individuals...
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Urban Science, Vol. 3, Pages 100: A Machine Learning Approach to Study the Relationship between Features of the Urban Environment and Street Value Urban Science doi: 10.3390/urbansci3030100 Authors: Venerandi Fusco Tettamanzi Emsellem Understanding what aspects of the urban environment are associated with bettersocioeconomic/liveability outcomes is a long standing research topic. Several quantitative studieshave investigated such relationships. However, most of such...
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Vaccines, Vol. 7, Pages 114: Tick Bites Induce Anti-α-Gal Antibodies in Dogs Vaccines doi: 10.3390/vaccines7030114 Authors: Adnan Hodžić Lourdes Mateos-Hernández Michael Leschnik Pilar Alberdi Ryan O. M. Rego Marinela Contreras Margarita Villar José de la Fuente Alejandro Cabezas-Cruz Georg Gerhard Duscher Due to the functional inactivation of the gene encoding for the enzyme that is involved in the oligosaccharide galactose-α-1,3-galactose (α-Gal)...
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Veterinary Sciences, Vol. 6, Pages 74: Long-Term Effects of Dietary Olive Oil and Hydrogenated Vegetable Oil on Expression of Lipogenic Genes in Subcutaneous Adipose Tissue of Dairy Cows Veterinary Sciences doi: 10.3390/vetsci6030074 Authors: Einar Vargas-Bello-Pérez Massimo Bionaz Pietro Sciarresi-Arechabala Nathaly Cancino-Padilla María Sol Morales Jaime Romero Heidi Leskinen Philip C. Garnsworthy Juan J. Loor The objective of this study was to characterize...
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Viruses, Vol. 11, Pages 860: Genetic Diversity of the Hepatitis B Virus Subgenotypes in Brazil Viruses doi: 10.3390/v11090860 Authors: Barbara V. Lago Marcia P. do Espirito-Santo Vanessa D. Costa Vanessa A. Marques Livia M. Villar Lia L. Lewis-Ximenez Elisabeth Lampe Francisco C. A. Mello Hepatitis B virus (HBV) subgenotypes may be related to clinical outcomes and response to antiviral therapy. Most Brazilian studies on HBV subgenotypes are restricted to some regions...
Viruses, Vol. 11, Pages 859: Recombination in Enteroviruses, a Multi-Step Modular Evolutionary Process Viruses doi: 10.3390/v11090859 Authors: Muslin Kain Bessaud Blondel Delpeyroux RNA recombination is a major driving force in the evolution and genetic architecture shaping of enteroviruses. In particular, intertypic recombination is implicated in the emergence of most pathogenic circulating vaccine-derived polioviruses, which have caused numerous outbreaks of paralytic...
Viruses, Vol. 11, Pages 855: Puumala and Tula Virus Differ in Replication Kinetics and Innate Immune Stimulation in Human Endothelial Cells and Macrophages Viruses doi: 10.3390/v11090855 Authors: Bourquain Bodenstein Schürer Schaade Old world hantaviruses cause hemorrhagic fever with renal syndrome (HFRS) upon zoonotic transmission to humans. In Europe, the Puumala virus (PUUV) is the main causative agent of HFRS. Tula virus (TULV) is also widely distributed in Europe, but...
Viruses, Vol. 11, Pages 858: Hematological Malignancies and HBV Reactivation Risk: Suggestions for Clinical Management Viruses doi: 10.3390/v11090858 Authors: Alessandra Zannella Massimo Marignani Paola Begini It is well known that hepatitis B virus reactivation (HBVr) can occur among patients undergoing treatment for hematological malignancies (HM). The evaluation of HBVr risk in patients undergoing immunosuppressive treatments is a multidimensional process, which includes conducting...
Viruses, Vol. 11, Pages 856: Vesiculopolins, a New Class of Anti-Vesiculoviral Compounds, Inhibit Transcription Initiation of Vesiculoviruses Viruses doi: 10.3390/v11090856 Authors: Ogino Fedorov Adams Okada Ito Sugiyama Ogino Vesicular stomatitis virus (VSV) represents a promising platform for developing oncolytic viruses, as well as vaccines against significant human pathogens. To safely control VSV infection in humans, small-molecule drugs that selectively...
Viruses, Vol. 11, Pages 854: Diversity and Host Specificity Revealed by Biological Characterization and Whole Genome Sequencing of Bacteriophages Infecting Salmonella enterica Viruses doi: 10.3390/v11090854 Authors: Fong Tremblay Delaquis Goodridge Levesque Moineau Suttle Wang Phages infecting members of the opportunistic human pathogen, Salmonella enterica, are widespread in natural environments and offer a potential source of agents that could be used...
Viruses, Vol. 11, Pages 857: Highly Divergent Genetic Variants of Soricid-Borne Altai Virus (Hantaviridae) in Eurasia Suggest Ancient Host-Switching Events Viruses doi: 10.3390/v11090857 Authors: Kang Gu Yashina Cook Yanagihara With the recent discovery of genetically distinct hantaviruses (family Hantaviridae) in shrews (order Eulipotyphla, family Soricidae), the once-conventional view that rodents (order Rodentia) served as the primordial reservoir hosts now appears...
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