Background: Trigeminal neuralgia (TN) is a rare and debilitating craniofacial pain syndrome often caused by vascular compression of the trigeminal nerve. Gamma Knife radiosurgery (GKRS) has been shown to offer a less invasive yet effective treatment method for pain reduction in TN. In this case report, we observed radiological evidence of resolved neurovascular compression after 11 years for a patient with recurrent TN and prior GKRS. Case Report: A 72-year-old female presented with TN and radiological...
Thu Sep 05, 2019 17:05
Publication date: Available online 4 September 2019Source: Journal of Neuroscience MethodsAuthor(s): Natalia Kosior, Terri L. Petkau, Colúm Connolly, Ge Lu, Blair R. LeavittAbstractBackgroundTheCre/loxP system allows for the temporal and spatial investigation of the expression of a single gene in the nervous system. Current methods of validating conditional knock-out mouse models rely on heterogeneous brain tissue or primary culture. These methods may assess the extent of genetic knockdown in the...
Thu Sep 05, 2019 13:41
Abstract Purpose Diffuse intrinsic pontine glioma (DIPG) is a lethal high-grade pediatric brainstem tumor without a cure. Despite numerous clinical trials over the last decades, the prognosis has remained poor. The aim of this update was to report on the status and outcomes of all clinical trials for DIPG performed to better understand the landscape of research efforts for this diagnosis to date. ...
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Publication date: 15 November 2019Source: NeuroImage, Volume 202Author(s): Elisabeth Parés-Pujolràs, Yong-Wook Kim, Chang-Hwan Im, Patrick HaggardAbstractAn experience of intention to move accompanies execution of some voluntary actions. The Readiness Potential (RP) is an increasing negativity over motor brain areas prior to voluntary movement. Classical studies suggested that the RP starts before intention is consciously accessed as measured by offline recall-based reports, yet the interpretation...
Thu Sep 05, 2019 13:33
BACKGROUND AND PURPOSE:The internal cerebral vein begins at the foramen of Monro by the union of the thalamostriate and the anterior septal veins. The lateral direct vein is its other major tributary. Numerous researchers have reported differences in internal cerebral vein branching patterns but did not classify them. Hence, the objectives of this study were to evaluate the anatomy of the internal cerebral vein and its primary tributaries and classify them depending on their course patterns using...
Thu Sep 05, 2019 19:18
BACKGROUND AND PURPOSE:The Woven EndoBridge 17 has recently been introduced to the market for facilitated endovascular treatment of small bifurcation aneurysms (≤7 mm) with low-profile microcatheters. We compared the Woven EndoBridge 17 with its predecessor versions in terms of procedural safety and feasibility.MATERIALS AND METHODS:This was a multicenter review of aneurysms ranging from 3 to 7 mm treated with the Woven EndoBridge between 2011 and 2019. Aneurysm characteristics, procedural parameters,...
Thu Sep 05, 2019 19:18
BACKGROUND AND PURPOSE:Secondary prevention of ischemic stroke depends on determining the cause of the initial ischemic event, but standard investigations often fail to identify a cause or identify multiple potential causes. The purpose of this study was to characterize the impact of intracranial vessel wall MR imaging on the etiologic classification of ischemic stroke.MATERIALS AND METHODS:This was a single-center, retrospective study of 205 consecutive patients who were referred for vessel wall...
Thu Sep 05, 2019 19:18
Thu Sep 05, 2019 19:18
Abstract: A 35-year-old healthy African-American woman presented with a 4-month history of gradual loss of vision in the right eye from an optic neuropathy. MRI of the orbits with gadolinium showed isolated thickening and enhancement of the right optic nerve sheath. Chest x-ray and CT-scan of the chest were performed and showed bilateral hilar and mediastinal lymphadenopathy. This was suggestive of sarcoidosis, and the diagnosis was confirmed with histopathology. The patient promptly recovered...
Thu Aug 29, 2019 03:00
No abstract available
Thu Aug 29, 2019 03:00
Publication date: Available online 4 September 2019Source: Brain Research BulletinAuthor(s): Li Liu, Huang Xu, Shumin Ding, Dongyan Wang, Guoqiang Song, Xianfeng HuangAbstractAlzheimer’s disease (AD), characterized by a progressive impairment of memory and cognition, is a major health problem in both developing and developed countries. Currently, no drugs can reverse the progression of AD. Phosphodiesterase 5 (PDE5) is a critical component of the cyclic guanosine monophosphate/protein kinase G (cGMP/PKG)...
Thu Sep 05, 2019 13:15
Publication date: November 2019Source: World Neurosurgery, Volume 131Author(s): Bernard R. Bendok, Karl R. Abi-Aad, Rudy J. Rahme, Evelyn L. Turcotte, Matthew E. Welz, Devi P. Patra, Ryan Hess, Brian Kalen, Chandan Krishna, Hunt H. BatjerIn this video, we present the case of a 61-year-old female who was brought to the emergency department after she had partial complex seizures. Computed tomography and magnetic resonance imaging of the brain revealed a right temporal lobe mass, which was initially...
Thu Sep 05, 2019 13:33
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