BACKGROUND Intralesional methotrexate (il-MTX) has been used as neoadjuvant therapy for cutaneous squamous cell carcinoma (cSCC) but studies on its effects on tumor thickness are lacking. OBJECTIVE The objective of this study was to evaluate il-MTX response with ultrasound examination. METHODS The authors conducted a prospective study in 40 patients with histologically confirmed cSCC. Neodjuvant il-MTX therapy was administered before surgery. Ultrasound evaluation was performed before...
Wed Apr 01, 2020 03:00
No abstract available
Wed Apr 01, 2020 03:00
No abstract available
Wed Apr 01, 2020 03:00
BACKGROUND Striae distensae have notoriously been difficult to treat due to their extensive involvement of nonfacial skin. Microneedling with its lack of thermal injury during microneedling treatment renders it a viable treatment option in darker skin tones and nonfacial regions due to the reduced risk of postinflammatory hyperpigmentation. OBJECTIVE To describe the clinical results and side effects of microneedling in a series of 25 individuals with striae distensae. MATERIALS AND METHODS...
Wed Apr 01, 2020 03:00
No abstract available
Wed Apr 01, 2020 03:00
BACKGROUND There is a growing trend toward the use of blunt-tip microcannulas for the treatment of midface volume loss with injectable hyaluronic acid. OBJECTIVE To evaluate the safety and efficacy of large gel particle hyaluronic acid with lidocaine, injected with a blunt-tip microcannula, for cheek augmentation and the correction of age-related midface contour deficiency. MATERIALS AND METHODS Sixty subjects with mild to substantial loss of midface fullness were treated to optimal...
Wed Apr 01, 2020 03:00
No abstract available
Wed Apr 01, 2020 03:00
No abstract available
Wed Apr 01, 2020 03:00
BACKGROUND The V-Y island advancement flap is a useful reconstruction technique for nasal alar defects, but flap mobility is limited by the insertion of the muscles of facial expression into the dermis of the alae. OBJECTIVE To describe a V-Y muscle sling myocutaneous island advancement flap (SMIAF) for improved mobility and intrasubunit reconstruction of alar defects. MATERIALS AND METHODS A retrospective review of patient records and preoperative and postoperative photographs was performed...
Wed Apr 01, 2020 03:00
BACKGROUND Full-face aesthetic treatment involving several treatment modalities may improve facial aesthetic outcome. OBJECTIVE To evaluate clinical outcomes and patient perceptions of monotherapy with either abobotulinumtoxinA (ABO) or hyaluronic acid (HA) filler followed by full-face combination treatments of ABO, HA filler, and skin-boosting HA (RSB). MATERIALS AND METHODS Subjects aged 35 to 50 years were randomized to monotherapy with 50 s.U ABO in the glabella or ≤1 mL HA filler...
Wed Apr 01, 2020 03:00
No abstract available
Wed Apr 01, 2020 03:00
BACKGROUND OnabotulinumtoxinA treatment for glabellar lines (GL) or crow's-feet lines (CFL) was previously studied in Japanese subjects. OBJECTIVE To assess safety and efficacy of repeated onabotulinumtoxinA for moderate to severe GL and CFL in Japanese subjects. METHODS This 13-month, double-blind, Phase 3 study randomized subjects to onabotulinumtoxinA 44 U (n = 48) or 32 U (n = 53) for CFL and GL for up to 5 treatments (CFL: 24 U or 12 U; GL: 20 U). Outcomes included proportion of...
Wed Apr 01, 2020 03:00
No abstract available
Wed Apr 01, 2020 03:00
BACKGROUND Bleomycin sclerotherapy is ineffective for treating capillary malformations (CMs) because bleomycin cannot adequately be injected into the small-diameter capillary lumina. Electrosclerotherapy (EST) might be a new treatment modality for CMs, as it combines bleomycin sclerotherapy and “electroporation”—an electric field applied to the tissue. Electroporation disrupts the transmembrane potential, facilitating bleomycin transportation across the vessel wall, hypothetically leading to targeted...
Wed Apr 01, 2020 03:00
BACKGROUND Platelet-rich plasma (PRP) is an increasingly popular treatment modality for various dermatologic conditions, but there are limitations in both the published literature and clinician knowledge. OBJECTIVE To create a high-yield, in-depth analysis of PRP in procedural dermatology by reviewing available data on its role in hair restoration, soft-tissue remodeling, resurfacing, and rejuvenation; identifying practice gaps and controversies; and making suggestions for future research...
Wed Apr 01, 2020 03:00
No abstract available
Wed Apr 01, 2020 03:00
BACKGROUND Lentigo maligna (LM) is associated with disproportionately high surgical morbidity. OBJECTIVE The authors report on 2 strategies to reduce the surgical morbidity associated with LM. METHODS Forty LM lesions were removed with excisional biopsies without margins and closed with purse-string sutures. Invasive cases underwent staged excisions with 10-mm margins. Cases without invasion were treated with neoadjuvant topical imiquimod 5% cream (5 d/wk × 8 weeks) followed by conservative...
Wed Apr 01, 2020 03:00
BACKGROUND Telemedicine is an emerging field with numerous applications within medicine. Previous review articles describe its use within plastic surgery and otolaryngology but none, to the authors' knowledge, within dermatologic surgery. OBJECTIVE To provide a review of the applications of telemedicine within dermatologic surgery. MATERIALS AND METHODS A PubMed search of articles published on teledermatology was conducted in July 2018. Articles were selected based on their relevance...
Wed Apr 01, 2020 03:00
No abstract available
Wed Apr 01, 2020 03:00
BACKGROUND Telemedicine is improving access to subspecialty care within the Veterans Health Administration (VHA). Mohs micrographic surgery (MMS) is a surgical modality used to treat nonmelanoma skin cancers. OBJECTIVE This study evaluates the use of teledermatology for preoperative consultation for MMS. METHODS AND MATERIALS A retrospective analysis of interfacility MMS referrals to the Bronx Veterans Affairs Medical Center (VAMC) was conducted. The consult failure rates (CFRs), treatment...
Wed Apr 01, 2020 03:00
No abstract available
Wed Apr 01, 2020 03:00
BACKGROUND Postoperative concerns after Mohs micrographic surgery (MMS) are not well characterized. OBJECTIVE To better define patient concerns and contributing characteristics in the immediate postoperative period after MMS. MATERIALS AND METHODS A standardized telephone encounter template was implemented to better assess patient concerns in the 24-hour postoperative period. A review was then performed of patients undergoing MMS from October 2016 to July 2017 to assess for the most...
Wed Apr 01, 2020 03:00
No abstract available
Wed Apr 01, 2020 03:00
Commentary on Patient Concerns in the Immediate Postoperative Period After Mohs Micrographic Surgery
No abstract available
Wed Apr 01, 2020 03:00
No abstract available
Wed Apr 01, 2020 03:00
BACKGROUND Repair of periocular defects poses unique functional and aesthetic challenges. Data on the safety of periocular repairs by Mohs surgeons are limited. OBJECTIVE Analyze the frequency and types of postreconstruction complications encountered with periocular repairs performed by Mohs surgeons, identify risk factors associated with complications, and enumerate interventions for complications encountered. MATERIALS AND METHODS An institutional review board–approved retrospective...
Wed Apr 01, 2020 03:00
No abstract available
Wed Apr 01, 2020 03:00
BACKGROUND Pathologists sometimes include commentary on margin involvement in shave biopsy reports of keratinocyte carcinoma (KC). This practice can lead to confusion regarding the need for further treatment. There is limited literature evaluating the reliability of reported histologic margin status in shave biopsies of KC. OBJECTIVE To evaluate the negative predictive value (NPV) of reported clear shave biopsy margins in basal and squamous cell carcinomas to determine whether this assessment...
Wed Apr 01, 2020 03:00
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