Πέμπτη 2 Απριλίου 2020


Inflammation-induced hypoparathyroidism triggered by combination immune checkpoint blockade for melanoma.
Related ArticlesInflammation-induced hypoparathyroidism triggered by combination immune checkpoint blockade for melanoma. J Immunother Cancer. 2019 02 21;7(1):52 Authors: Trinh B, Sanchez GO, Herzig P, Läubli H Abstract BACKGROUND: Treatment with a combination of PD-1 and CTLA-4 targeted checkpoint inhibition has improved outcome of melanoma patients and led to durable remissions but is also associated with significant toxicities. Endocrinopathies...
Rare Cancers
Wed Apr 01, 2020 13:15
A Rare Case of Cutaneous Metastases Secondary to Hepatocellular Carcinoma.
Related ArticlesA Rare Case of Cutaneous Metastases Secondary to Hepatocellular Carcinoma. Clin Gastroenterol Hepatol. 2019 02;17(3):e17 Authors: Alsahhar JS, Idriss R, Bahirwani R PMID: 29353009 [PubMed - indexed for MEDLINE]
Rare Cancers
Wed Apr 01, 2020 13:15
New anatomical information on Dsungaripterus weii Young, 1964 with focus on the palatal region
Pterosaur specimens with complete and well-preserved palatal region are rare. Here we describe new and previously collected specimens of the pterodactyloid pterosaur Dsungaripterus weii that are three-dimensionally preserved and provide new anatomical information for this species. Among the unique features is a lateral process of the pterygoid divided into two parts: an anterior thin, parabolic arc shaped element that separates the secondary subtemporal and the subtemporal fenestrae, followed by...
PeerJ Computer Science
Wed Apr 01, 2020 03:00
Prediction of antiviral drugs against African swine fever viruses based on protein–protein interaction analysis
The African swine fever virus (ASFV) has severely influenced the swine industry of the world. Unfortunately, there is currently no effective antiviral drug or vaccine against the virus. Identification of new anti-ASFV drugs is urgently needed. Here, an up-to-date set of protein–protein interactions between ASFV and swine were curated by integration of protein–protein interactions from multiple sources. Thirty-eight swine proteins were observed to interact with ASFVs and were defined as ASFV-interacting...
PeerJ Computer Science
Wed Apr 01, 2020 03:00
The efficiency of universal mitochondrial DNA barcodes for species discrimination of Pomacea canaliculata and Pomacea maculata
Invasive apple snails, Pomacea canaliculata and P. maculata, have a widespread distribution globally and are regarded as devastating pests of agricultural wetlands. The two species are morphologically similar, which hinders species identification via morphological approaches and species-specific management efforts. Advances in molecular genetics may contribute effective diagnostic tools to potentially resolve morphological ambiguity. DNA barcoding has revolutionized the field of taxonomy by providing...
PeerJ Computer Science
Wed Apr 01, 2020 03:00
Artificial intelligence system can achieve comparable results to experts for bone age assessment of Chinese children with abnormal growth and development
Objective Bone age (BA) is a crucial indicator for revealing the growth and development of children. This study tested the performance of a fully automated artificial intelligence (AI) system for BA assessment of Chinese children with abnormal growth and development. Materials and Methods A fully automated AI system based on the Greulich and Pyle (GP) method was developed for Chinese children by using 8,000 BA radiographs...
PeerJ Computer Science
Wed Apr 01, 2020 03:00
Interaction effects of aging, word frequency, and predictability on saccade length in Chinese reading
Background It was well known that age has an impact on word processing (word frequency or predictability) in terms of fixating time during reading. However, little is known about whether or not age modulates these impacts on saccade behaviors in Chinese reading (i.e., length of incoming/outgoing saccades for a target word). Methods Age groups, predictability, and frequency of target words were manipulated in the present...
PeerJ Computer Science
Wed Apr 01, 2020 03:00
Palustrine forested wetland vegetation communities change across an elevation gradient, Washington State, USA
Background Forested wetlands support distinct vegetation and hydrology relative to upland forests and shrub-dominated or open water wetlands. Although forested wetland plant communities comprise unique habitats, these ecosystems’ community structure is not well documented in the U.S. Pacific Northwest. Here I surveyed forested wetland vegetation to identify changes in community composition and structure across an elevation gradient that corresponds to flooding stress, asking: (1) How do forested...
PeerJ Computer Science
Wed Apr 01, 2020 03:00
Comparison of visible and UVA phototoxicity in neural culture systems micropatterned with digital projection photolithography.
Related ArticlesComparison of visible and UVA phototoxicity in neural culture systems micropatterned with digital projection photolithography. J Biomed Mater Res A. 2019 01;107(1):134-144 Authors: Khoshakhlagh P, Bowser DA, Brown JQ, Moore MJ Abstract Photopolymerization provides a favorable method for hydrogel formation due to its simplicity, convenience, and versatility. However, the light exposure required to initiate photopolymerization is known...
low levels of ultrav...
Wed Apr 01, 2020 13:14
Outcomes of sinonasal mucosal melanomas with endoscopic and open resection: a retrospective cohort study.
Related ArticlesOutcomes of sinonasal mucosal melanomas with endoscopic and open resection: a retrospective cohort study. J Neurooncol. 2020 Mar 29;: Authors: Almutuawa DM, Strohl MP, Gruss C, van Zante A, Yom SS, McDermott MW, El-Sayed IH Abstract PURPOSE: To compare the outcomes of Sinonasal Mucosal Melanomas (SNMM) treated with endoscopic and open resection. METHODS: A retrospective case review of 20 patients with SNMM treated surgically...
Skull Base
Wed Apr 01, 2020 13:13
[Subtotal petrosectomy - indications, surgical technique, experiences in Pécs].
Related Articles[Subtotal petrosectomy - indications, surgical technique, experiences in Pécs]. Orv Hetil. 2020 Apr;161(14):544-553 Authors: Gerlinger I, Molnár K, Nepp N, Tóth I, Tóth T, Szanyi I, Bakó P, Pap I Abstract Introduction: Subtotal petrosectomy (STP) has been known for decades and it is considered being on the borderline between ear and skull-base surgery. Due to its excessive radicalism and adverse effects on hearing, it has been a forgotten...
Skull Base
Wed Apr 01, 2020 13:13

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